Measurement of Corneal Biomechanical Properties using Corneal Visualisation Scheimpflug Technology and Ocular Response Analyser in Healthy Saudi Female Adults: A Cross-sectional Study by Farah Maqsood, Noura Aldossari, Menwah Al Matrafi, Musarat Amina, Maram M Bawazir

“…The IOP, CCT, and the corneal biomechanical properties at the first applanation (time-T1, velocity-V1, length-L1, deformation amplitude-DA1), second applanation (time-T2, velocity-V2, length-L2, deformation amplitude-DA2), highest concavity (Highest Concavity Time-HCT, Highest Concavity Radius-HCR, Highest Concavity Deformation Amplitude-HCDA), and Peak Distance (PD) were evaluated by using Corneal Visualisation Scheimpflug Technology (CST) whereas, Ocular Response Analyser (ORA) was used for the comparison of biomechanical properties. …”
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Psychometric validation of the Chronic Ocular Pain Questionnaire (COP-Q) by Amy Findley, Brigitte J. Sloesen, Nicola Hodson, Agkreta Leventi, Ben Pascoe, Rob Arbuckle, Paul O’Brien, Christel Naujoks, Michela Montecchi-Palmer, Diana Plaza, Paul M. Karpecki, Pedram Hamrah

“…Abstract Background The Chronic Ocular Pain Questionnaire (COP-Q) is a newly developed patient-reported outcome (PRO) measure intended to assess symptoms and impacts associated with Chronic Ocular Surface Pain (COSP). …”
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Psychophysiological Acute Effects of Functional Neurology Intervention on Vestibulo-Ocular Reflex Dysfunction by Guillermo Escribano-Colmena, Jorge Rey-Mota, Ana Isabel Beltrán-Velasco, Vicente Javier Clemente-Suárez

“…<b>Conclusions</b>: The results of this study demonstrate that a single functional neurology intervention significantly improved psychophysiological responses and neuromuscular reflex performance in participants with vestibulo-ocular reflex (VOR) cancellation dysfunction. …”
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Application of lacrimal gland ultrasonography in the evaluation of chronic ocular graft-versus-host-disease by Mingxia Zhong, Siyuan Liu, Jinghan Luo, Qin Zhang, Zhou Yang, Shanshan Zhang

“…Lacrimal gland structures were assessed by B-mode and Doppler ultrasonography to measure parameters such as the long diameter, thick diameter, homogeneity and parenchymal vascularization. Statistical analyses were performed to determine differences in ocular surface conditions and lacrimal gland ultrasonographic parameters between groups as well as to determine the correlation between ocular surface condition and lacrimal gland ultrasonographic findings.Result(1) Patients with definite and probable oGVHD exhibited a significantly longer duration after allo-HSCT compared to non-oGVHD patients (H=11.264, p&lt;0.01), The median durations were 247(164,894) days and 525(310,928) days, respectively, compared to 204(169,323.25) days for non-oGVHD patients. (2) Compared to non-oGVHD patients, both definite oGVHD patients and probable oGVHD patients showed lower average of Schirmer test (H=31.188, p&lt;0.01), TBUT (H=11.853, p&lt;0.01), tear meniscus height (H=13.630, p&lt;0.01) and higher average of OSDI (F=27.992, p&lt;0.01), corneal staining scores (χ²=23.66, p&lt;0.05) and temporal conjunctival staining scores (χ²=14.84, p&lt;0.05). (3) The B-mode and Doppler ultrasonography parameters in lacrimal glands including long diameter, thick diameter, homogeneity and parenchymal vascularization did not exhibit significant differences between the three groups. (4) The long diameter in lacrimal ultrasonography had significantly positive correlations with tear meniscus height (r=0.297, p&lt;0.05) and significantly negative correlations with temporal conjunctival staining scores (r=-0.313, p&lt;0.05) and staining total scores (r=-0.285, p&lt;0.05). …”
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Otolith Degeneration with Aging: Insights from Video Ocular Counter-Roll (vOCR) Assessment by Melissa Castillo-Bustamante, Jorge Madrigal, Elizabeth Andalón-Dueñas, Johanna Marcela Vanegas, Ireri Espinoza

“…Background: Vestibular assessments, such as the video ocular counter roll (vOCR) test, offer valuable insights into the interactions between age, otolith function, and vestibular performance. …”
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The Association Between Refraction, Ocular Biometry, and a Child&rsquo;s Behavior Assessed by Conners&rsquo; Parental Rating Scale by Cohen Y, Eidel M, Greenberger Y, Vidan A, Chassid O

“…Cycloplegic refraction and ocular biometry were performed. Correlation analyses among the 14 behavioral scores, refraction, and biometry were performed. …”
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Targeting glial fibrillary acidic protein in glaucoma: a monoclonal antibody approach to modulate glial reactivity and neuroinflammation for neuroprotection by Chaoqiang Guan, Linglin Zhang, Kristian Nzogang Fomo, Jie Yang, Norbert Pfeiffer, Franz H. Grus

“…Retinal ganglion cell (RGC) survival and glial responses were evaluated with immunostaining. Western blot and microarray analyses were performed to investigate molecular and pathway alterations. …”
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Deciphering mitochondrial dysfunction in keratoconus: Insights into ACSL4 from machine learning-based bulk and single-cell transcriptome analyses and experimental validation by Yuchen Cai, Tianyi Zhou, Xueyao Cai, Wenjun Shi, Hao Sun, Yao Fu

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Impact of Preoperative Prism Adaptation Test and Patch Test Measurements on Surgery in Concomitant Horizontal Strabismus: A Prospective Interventional Study by Rahul Singh, Disha Chaudhary, Charu Sagar, Vandana Kohli

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Endogenous acrolein accumulation in akr7a3 mutants causes microvascular dysfunction due to increased arachidonic acid metabolism by Xin Zhang, Johannes Gschwind, Vanessa Erben, Katrin Bennewitz, Xiaogang Li, Carsten Sticht, Gernot Poschet, Ingrid Hausser, Thomas Fleming, Julia Szendroedi, Peter Paul Nawroth, Jens Kroll

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Retinal microvascular and microcirculatory responses related to cognition improvement following yoga training in patients with Parkinson’s disease by Hong Jiang, Kirill Stremousov, Yunhai Dai, Bonnie Levin, Amanda Virgets, Andrew Hoover, Kylie J. Martinez, Joseph Signorile, Jianhua Wang

“…Pearson correlation analyses determined the relationship between the changes in retinal microcirculatory responses and cognitive function. …”
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Antigen‐specific polyfunctional cytotoxic T cells differentiate intraocular from peripheral blood immune responses in posterior uveitis by Kaiser Alam, Arun Raina, Bibhuprasad Das, Sandhya Bhanja, Sayantan Ghosh, John V Forrester, Soumyava Basu

“…Abstract Objectives Peripheral blood is frequently used to study the immune response in human uveitis because of the inaccessibility of ocular tissue samples. …”
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Effect of repeated Low-Level red light therapy on axial length in myopic individuals: predictors for a good response by Daohuan Kang, Lu Yuan, Jia Feng, Rui Yu, Andrzej Grzybowski, Kai Jin, Wen Sun

“…Abstract Purpose This study aimed to investigate the effects of Repeated Low-Level Red Light (RLRL) therapy on axial length (AL) in myopic individuals and to identify key predictors for a good response to the treatment, with a focus on baseline ocular characteristics and treatment compliance. …”
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A Deep Learning Approach to Measure Visual Function in Zebrafish by Manjiri Patil, Annabel Birchall, Hammad Syed, Vanessa Rodwell, Ha-Jun Yoon, William H. J. Norton, Mervyn G. Thomas

“…Visual behaviour in zebrafish, often measured by the optokinetic reflex (OKR), serves as a valuable model for studying aspects of human neurological and ocular diseases and for conducting therapeutic or toxicology assays. …”
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Peripapillary retinal nerve fiber layer following vessel density correction at different IOP values by Jan Lestak, Martin Fus, Sarka Pitrova

“…IOP was measured using the Ocular Response Analyser (ORA). VD and RNFL were measured peripapillary by OCT (Avanti RTVue XR) in eight segments: Inferior Temporal - IT (1); Temporal Inferior - TI (2); Temporal Superior - TS (3); Superior Temporal - ST (4); Superior Nasal - SN (5); Nasal Superior - NS (6); Nasal Inferior - NI (7) and Inferior Nasal - IN (8). …”
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Metabolomic insights into vitreous humor with therapy outcome in type 2 diabetic retinopathy by Yuxu Hao, Xiangjun She, Gongyu Huang, Xuyang Chu, Shixin Zhao, Zhe Lv, Jiwei Tao, Yun Zhang

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Identifying prioritization of therapeutic targets for ankylosing spondylitis: a multi-omics Mendelian randomization study by Lingyu Dai, Lan Xia, Guannan Su, Yu Gao, Qingyan Jiang, Peizeng Yang

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Myopic choroidal neovascularization with dilated choroid vessels is prone to progression into subretinal fibrosis following anti-vascular endothelial growth factor therapy: a retro... by Xiangjun She, Qiwei Cai, Wangjing Yao, Shixin Zhao, Zhe Lv, Suyan Shan, Jiwei Tao, Yun Zhang

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Revealing the structural microenvironment of high metastatic risk uveal melanomas following decellularisation by Karen Aughton, Joshua Hattersley, Sarah E Coupland, Helen Kalirai

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“Infectious uveitis: a comprehensive systematic review of emerging trends and molecular pathogenesis using network analysis” by Muhammad Arif Asghar, Shixin Tang, Li Ping Wong, Peizeng Yang, Qinjian Zhao

“…Pathogenesis involves complex interactions between infectious agents and the ocular immune response, with key roles for cytokines and chemokines. …”
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