Symptom Network and Subgroup Analysis in Patients with Exacerbation of Chronic Obstructive Pulmonary Disease: A Cross-Sectional Study by Yu C, Xu M, Pang X, Zhang Y, Cao X, Xu Y, Huang S, Zhao H, Chen C

“…Chunchun Yu,1 Mengying Xu,1 Xinyue Pang,2 Yuting Zhang,3 Xinmei Cao,2 Yixin Xu,1 Shuai Huang,1 Hongjun Zhao,4 Chengshui Chen1,3,4 1Key Laboratory of Interventional Pulmonology of Zhejiang Province, Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, People’s Republic of China; 2Zhejiang Province, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, People’s Republic of China; 3Cixi Biomedical Research Institute, Wenzhou Medical University, Wenzhou, Zhejiang, 315302, People’s Republic of China; 4Zhejiang Province Engineering Research Center for Endoscope Instruments and Technology Development, Department of Pulmonary and Critical Care Medicine, Quzhou People’s Hospital, The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou, 324000, People’s Republic of ChinaCorrespondence: Hongjun Zhao; Chengshui Chen, Zhejiang Province Engineering Research Center for Endoscope Instruments and Technology Development, Department of Pulmonary and Critical Care Medicine, Quzhou People’s Hospital, The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou, 324000, People’s Republic of China, Email zhaohongjun@wmu.edu.cn; chenchengshui@wmu.edu.cnPurpose: This study aims to construct a contemporaneous symptom network of inpatients with Exacerbation of Chronic Obstructive Pulmonary Disease (ECOPD) based on the symptom cluster, identify core and bridge symptoms, and patient subgroups with different symptom clusters based on individual differences in the intensity of patient symptom experiences.Patients and Methods: This study used convenience sampling to collect demographic, symptom, auxiliary examination, and prognosis information of 208 inpatients with ECOPD from April 2022 to October 2023. …”
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Identification of telomere maintenance related biomarkers and regulatory mechanisms in chronic obstructive pulmonary disease by machine learning algorithm by Haiyan Cao, Xiangjian Chu

“…Abstract Chronic obstructive pulmonary disease (COPD) is a progressive respiratory disease that accelerates the aging process of the lung. …”
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Causal analysis of education attainment and brain structure in chronic obstructive pulmonary disease: a Mendelian randomization study by Shaochu Zheng, Xiaotong Liu, Jinliang Kong, Jing Luo

“…Methods First, we performed a two-sample Mendelian randomization (MR) analysis to investigate the relationship between educational attainment and COPD. …”
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Evaluation of DAZ1 Gene Expression in Spermatogenic Failure among Infertile Non-Obstructive Azoospermic Iraqi Males by I Abd Ali Al-Humairi, HA Karbal, AA Abid Albdairi

“…Background and Objective: Non-obstructive azoospermia (NOA) is one of the causes of male infertility. …”
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Identifying the Core Symptoms in Chinese Patients of Chronic Obstructive Pulmonary Disease: A Contemporaneous Symptom Network Analysis by Yang Z, Cui M, Zhang J, Wang Z, Yao G, Fu X

“…Latent profile analysis (LPA) was conducted to identify symptom subgroups, while network analysis was used to reveal core symptoms among subgroups identified by LPA.Results: Based on symptom experiences, two subgroups of patients were identified: the “low” symptom burden subgroup and the “high” symptom burden subgroup. In both the total sample and the low symptom burden subgroup, “feeling sad” was identified as the core symptom, whereas “feeling drowsy” was the core symptom in the high symptom burden subgroup. …”
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Relationship between Nasal Septum Deviation and Size of Inferior Turbinate in Obstructive Sleep Apnea: A Systematic Review by K.M Veena, A. M Mohamed Sharuff, Prashanth Shenoy, Laxmikanth Chatra, Rachana V. Prabhu, Prathima Shetty

“…Background: Obstructive sleep apnea is increasing in prevalence, with multiple risk factors, but the relationship between nasal septum deviations and inferior turbinate size remains controversial. …”
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Evaluating Hypoglossal Nerve Stimulation Outcomes in Obstructive Sleep Apnea: Impact of Predisposing Conditions in a Retrospective Cohort by Lina Adwer

“… Background: This retrospective study aimed to analyze treatment outcomes for patients receiving a hypoglossal nerve stimulation (HNS) device for obstructive sleep apnea (OSA). Methods: Chart reviews were conducted for HNS patients who underwent a post-implantation polysomnography (PSG) (typically performed approximately 2 months after device activation) to assess therapeutic response and optimize stimulation settings. …”
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Different Airway Inflammatory Phenotypes Correlate with Specific Fungal and Bacterial Microbiota in Asthma and Chronic Obstructive Pulmonary Disease by Rui Yang, Qiao Zhang, Zhidong Ren, Hong Li, Qianli Ma

“…Methods. Induced sputum samples were collected from 45 asthma subjects and 39 COPD subjects. …”
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Obstructive sleep apnea and hypopnea syndrome in patients admitted in a tertiary hospital in Cameroon: Prevalence and associated factors. by Virginie Poka-Mayap, Dodo Balkissou Adamou, Massongo Massongo, Steve Voufouo Sonwa, Jacqueline Alime, Ben Patrick Michel Moutlen, Alfred Kongnyu Njamnshi, Andre Noseda, Eric Walter Pefura-Yone

“…<h4>Purpose</h4>Obstructive sleep apnea and hypopnea syndrome (OSAHS) is poorly documented in Sub-Saharan Africa, especially in the hospital setting. …”
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The lower airways microbiome and antimicrobial peptides in idiopathic pulmonary fibrosis differ from chronic obstructive pulmonary disease. by Kristel S Knudsen, Sverre Lehmann, Rune Nielsen, Solveig Tangedal, Ingvild Haaland, Pieter S Hiemstra, Tomas M Eagan

“…We aimed to investigate possible microbiome characteristics and key antimicrobial peptides and proteins in idiopathic pulmonary fibrosis (IPF) and chronic obstructive pulmonary disease (COPD).<h4>Methods</h4>12 IPF patients, 12 COPD patients and 12 healthy controls were sampled with oral wash (OW), protected bronchoalveolar lavage (PBAL) and right lung protected sterile brushings (rPSB). …”
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Predictive Value of Natriuretic Peptide Tests and Ischemia Modified Albumin Levels in the Diagnosis of Obstructive Sleep Apnoea Syndrome by Hamza Ogun, Eray Metin Güler, Beyza Nur Özkan, Muhammed Yunus Bektay, Abdullah Kansu, Ömer Faruk Çalım

“…Objective:To investigate the relationship between obstructive sleep apnoea (OSA) severity and oxygen desaturation with biomarkers including ischaemia-modified albumin (IMA), interleukin-1β (IL-1β), thiol/ disulphide homeostasis parameters, and cardiac biomarkers (BNP, NT-proBNP). …”
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Association of Tumor Necrosis Factor Alpha and Lymphotoxin Alpha Gene Polymorphisms with the Presence of Chronic Obstructive Pulmonary Disease by Amira P Tarigan, Tamsil Syafiuddin, Faisal Yunus, Suradi Suradi

“… Aim: to analyze the occurrence of chronic obstructive pulmonary disease (COPD) and its association with the polymorphisms of -308G/A, -238G/A of TNFα gene and +252A/G LTα gene polymorphism in smokers. …”
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Correlation of mean platelet volume and red blood cell distribution width with obstructive sleep apnoea syndrome severity by Kyriaki Cholidou, Nektarios Anagnostopoulos, Konstantinos Bartziokas, Konstantinos Vafeiadis, Agamemnon Bakakos, Aggelos Vontetsianos, Vasiliki Gogou, Zoi Sotiropoulou, Christina Anagnostopoulou, Anna Papasarantou, Paschalis Steiropoulos, Petros Bakakos, Andriana I. Papaioannou

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Association of Tumor Necrosis Factor Alpha and Lymphotoxin Alpha Gene Polymorphisms with the Presence of Chronic Obstructive Pulmonary Disease by Amira P Tarigan, Tamsil Syafiuddin, Faisal Yunus, Suradi Suradi

“… Aim: to analyze the occurrence of chronic obstructive pulmonary disease (COPD) and its association with the polymorphisms of -308G/A, -238G/A of TNFα gene and +252A/G LTα gene polymorphism in smokers. …”
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Association of Tumor Necrosis Factor Alpha and Lymphotoxin Alpha Gene Polymorphisms with the Presence of Chronic Obstructive Pulmonary Disease by Amira P Tarigan, Tamsil Syafiuddin, Faisal Yunus, Suradi Suradi

“… Aim: to analyze the occurrence of chronic obstructive pulmonary disease (COPD) and its association with the polymorphisms of -308G/A, -238G/A of TNFα gene and +252A/G LTα gene polymorphism in smokers. …”
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Percutaneous nephrostomy versus ureteral stent in hydronephrosis secondary to obstructive urolithiasis: A systematic review and meta-analysis by Andreia Cardoso, Aparício Coutinho, Gonçalo Neto, Sara Anacleto, Catarina Laranjo Tinoco, Nuno Morais, Mário Cerqueira-Alves, Estevão Lima, Paulo Mota

“…Nevertheless, further studies with larger samples and a randomized controlled design are suggested.…”
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Respiratory events associated with concomitant opioid and sedative use among Medicare beneficiaries with chronic obstructive pulmonary disease by Tham Thi Le, Siyeon Park, Michelle Choi, Marniker Wijesinha, Bilal Khokhar, Linda Simoni-Wastila

“…Background Opioids and sedatives are commonly prescribed in chronic obstructive pulmonary disease (COPD) patients for symptoms of dyspnoea, pain, insomnia, depression and anxiety. …”
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A systematic review and meta-analysis of the association between serotonergic gene polymorphisms and obstructive sleep apnea syndrome. by Huajun Xu, Jian Guan, Hongliang Yi, Shankai Yin

“…<h4>Background</h4>5-Hydroxytryptamine receptor (5-HTR) and 5-hydroxytryptamine transporter (5-HTT) gene polymorphisms have been reported to be associated with susceptibility to obstructive sleep apnea syndrome (OSAS). The associations, derived from sporadic, inconsistent, small-sample-size studies, need to be evaluated further in a meta-analysis.…”
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Causal Associations Between Chronic Obstructive Pulmonary Disease and Common Comorbidities: Evidence from Comprehensive Genetic Methods by Ji J, Zhao Q, Yuan J, Yuan Z, Gao N

“…Therefore, causal relationships between diseases need to be explored by means of causal inference methods.Materials and Methods: Genetic correlation and two-sample Mendelian randomization (MR) analysis were explored to assess the causal relationship between exposures and outcomes with the genome-wide association studies (GWAS) dataset. …”
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The extracellular CIRP as a predictive marker for the endothelial dysfunction in chronic obstructive pulmonary disease combined with pulmonary hypertension by Yun Yao, Haibo Jiang, Dalin Xu, Bing Zhang, Feng Yao, Wei Guo

“…Abstract Background Pulmonary hypertension (PH) is a serious complication of chronic obstructive pulmonary disease (COPD), distinguished by pulmonary endothelial dysfunction. …”
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