Risk of physical health comorbidities in autistic adults: clinical nested cross-sectional study by Megan Hunt, Jack F. G. Underwood, Leon Hubbard, Jeremy Hall

“…Method We undertook a nested cross-sectional study, using a sample from the National Centre for Mental Health database. …”
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Impact of Sleep Respiratory Disorders on Endothelial Function in Children by Luigia Brunetti, Ruggiero Francavilla, Pietro Scicchitano, Valentina Tranchino, Maria Loscialpo, Michele Gesualdo, Annapaola Zito, Fara Fornarelli, Marco Sassara, Paola Giordano, Vito Leonardo Miniello, Marco Matteo Ciccone

“…Obstructive sleep apnea syndrome (OSAS) in children can induce endothelial dysfunction, a well-known early marker of atherosclerosis. …”
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Hypothesis on the role of cholesterol crystals in spontaneously ruptured aortic plaques: Potential triggers for inflammation and systemic effects by Chikao Yutani, Hirotaka Noda, Nobuzo Iwa, Sei Komatsu, Satoru Takahashi, Yoshiharu Higuchi, Kazuhisa Kodama

“…Spontaneously ruptured aortic plaques (SRAPs) are frequently observed via non-obstructive general angioscopy (NOGA) in patients with or suspected coronary artery disease. …”
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Functional analysis of a new splicing mutation in the <em>MYBPC3</em> gene in hypertrophic cardiomyopathy by R. R. Salakhov, M. V. Golubenko, M. Y. Skoblov, R. R. Savchenko, N. R. Valiakhmetov, E. N. Pavlyukova, M. S. Nazarenko

“…The study was conducted using a DNA sample obtained from a patient with hypertrophic cardiomyopathy, in whom a previously undescribed variant was identified in the splice donor site of intron 21. …”
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Telomere length in sleep disorders by Gülüstan Eşel, Özlem Olguner Eker, Ayaz Amraliyev, Akif Asdemir, Elif Özge Biçer, Damla Badur Mermer, Munis Dündar, Ertuğrul Eşel, Sevda İsmailoğulları

“…This study aims to demonstrate telomere length in sleep disorders. Methods: The study sample consisted of 116 participants, 94 patients and 22 healthy participants. …”
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First report of Angiostrongylus vasorum in an African golden wolf (Canis lupaster) in Algeria by Noureddine Mechouck, Georgiana Deak, Angela Monica Ionică, Corina Toma, Andrada Gabriela Negoescu, Marian Taulescu, Zihad Bouslama, Andrei Daniel Mihalca

“…Results Histological examination revealed the presence of nematode eggs and larvae in the alveolar space and chronic obstructive vascular changes were detected in a single golden African wolf (Canis lupaster) collected from the department of Constantine. …”
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Ozone exposure and health effects: a protocol for an umbrella review and effect-specific systematic maps by Joachim Heinrich, Dennis Nowak, Iana Markevych, Tianyu Zhao, Christian Janßen, Nadine Steckling-Muschack

“…Because the association between ozone exposure and chronic obstructive pulmonary disease (COPD) is relatively well investigated, we will at least conduct one systematic map of ozone and COPD.Ethics and dissemination No ethical approval is required for this study. …”
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Using and implementing care bundles for patients with acute admission for COPD: qualitative study of healthcare professionals’ experience in four hospitals in England by Sarah Purdy, Katherine Morton, Anna King, Sue Jenkins, Ali Shaw, Melanie Chalder, James Calvert

“…Within a wider multi-method evaluation of care bundles for adults with an emergency admission for acute exacerbations of chronic obstructive pulmonary disease, a qualitative study was conducted. …”
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Moraxella catarrhalis: A Cause of Concern with Emerging Resistance and Presence of BRO Beta-Lactamase Gene—Report from a Tertiary Care Hospital in South India by Savitha Raveendran, Gauri Kumar, R. N. Sivanandan, Mary Dias

“…Strains of M. catarrhalis were isolated from the respiratory samples submitted to the microbiology laboratory. …”
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Correlation of Platelet Indices with Severity of Gastroesophageal Varices in Patients of Liver Cirrhosis: A Research Protocol by Parav Tantia, Sourya Acharya

“…The Chi-square test and Independent sample t-test will be used to evaluate the association between various categorical variables and continuous variables. …”
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Validation of an AI-Powered Smart Dry Powder Inhaler (RS01X) for Asthma and COPD in a Clinical Setting by Chamaon D, Sportel E, Elferink ECM, van der Palen J

“…The inhalations differed in duration, volume and PIF, and orientation of the inhaler (horizontal (correct) and at a 45-degree angle (incorrect)). A paired sample t-test was performed to test for differences in the mean values between the smart DPI and the IPR. …”
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The Role of Neurotrophic Modulation in COPD and Its Influence on Airway Pathophysiology: A Systematic Review and Meta-Analysis by Zeeshan Hussain, Mona Rani, Soobia Pathan, Seemi Tanvir, Madeeha Minhas, Saif Ur Rahman, Muhammad Arsalan Shah

“… Background: Chronic obstructive pulmonary disease (COPD) is a chronic pulmonary disorder that is characterized by inflammation in the airways and their remodeling. …”
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Self-reported illnesses in Thatta: Evidence from a rural and underdeveloped district in Sindh province, Pakistan. by Muhammad Ashar Malik, Rahat Batool, Muhammad Ahmed, Imran Naeem Abbasi, Zafar Ahmed Fatmi, Sarah Saleem, Sameen Siddiqui

“…Urban inhabitants were more likely to have Chronic Obstructive Pulmonary Disorders (3.34%) and Diabetes (1.62%). …”
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Assessment of pharyngeal airway space with MRI In oral submucous fibrosis: A cross-sectional observational study by Ragavendiran Anandan, Krithika C. Lakshmi, Anuradha Ganesan, Yesoda AniyanK

“…Materials and methods: This study is a cross-sectional observational study that included a sample size of 42 patients. Group A consisted of 21 patients with OSMF, while Group B consisted of 21 volunteers without OSMF, who served as the control group. …”
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Transcriptional profiling of pediatric cholestatic livers identifies three distinct macrophage populations. by Sarah A Taylor, Shang-Yang Chen, Gaurav Gadhvi, Liang Feng, Kyle D Gromer, Hiam Abdala-Valencia, Kiwon Nam, Salina T Dominguez, Anna B Montgomery, Paul A Reyfman, Lorena Ostilla, Joshua B Wechsler, Carla M Cuda, Richard M Green, Harris Perlman, Deborah R Winter

“…<h4>Results</h4>We identified 3 distinct macrophage populations across cholestatic liver samples and annotated them as lipid-associated macrophages, monocyte-like macrophages, and adaptive macrophages based on their transcriptional profile. …”
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The predictive role of identifying frailty in assessing the need for palliative care in the elderly: the application of machine learning algorithm by Zahra Nejatifar, Ahad Alizadeh, Mohammad Amerzadeh, Shideh Omidian, Sima Rafiei

“…Methods The level of frailty in a sample of patients (total n = 140) was assessed using the checklist of frailty assessment, which encompasses five questions: measured decrease in body mass index (BMI), fatigue status, physical activity status, and walking speed. …”
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Effect of serum MMP-7 on the diagnostic accuracy of biliary atresia: systematic review and meta-analysis by Haojun Wang, Hui Liu, Wanfu Li, Ainiwaer Keranmu, Peng Liang, Yaqi Wang, Tao Zhang, Yeliaman Jiayilawu

“…BackgroundBiliary atresia (BA) is an obstructive fibrotic disorder that typically progresses to cirrhosis and, ultimately, death in children. …”
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Metabolism-related hepatokines change in biliary atresia: ANGPTL6 as a potential biomarker by Daiqiong Fang, Shuqi Hu, Jinfa Tou, Fengqin Dong, Shiqiao Peng

“…Abstract Objectives Biliary atresia (BA) is a severe obstructive cholangiopathy of early infancy that progresses to end-stage liver disease without any intervention. …”
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High-flow nasal cannula therapy for initial oxygen administration in acute hypercapnic respiratory failure: study protocol of randomised controlled unblinded trial by Bronagh Blackwood, Murali Shyamsundar, Asem Alnajada, Abdulmajeed Mobrad, Adeel Akhtar

“…Acute exacerbation of chronic obstructive pulmonary disease is the most common cause of AHRF. …”
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The Ser82 RAGE Variant Affects Lung Function and Serum RAGE in Smokers and sRAGE Production In Vitro. by Suzanne Miller, Amanda P Henry, Emily Hodge, Alexander K Kheirallah, Charlotte K Billington, Tracy L Rimington, Sangita K Bhaker, Ma'en Obeidat, Erik Melén, Simon K Merid, Caroline Swan, Catherine Gowland, Carl P Nelson, Ceri E Stewart, Charlotte E Bolton, Iain Kilty, Anders Malarstig, Stuart G Parker, Miriam F Moffatt, Andrew J Wardlaw, Ian P Hall, Ian Sayers

“…AGER/RAGE expression increased across developmental stages in human fetal lung at both the mRNA (38 samples) and protein levels (20 samples). Extensive AGER splicing was identified. …”
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