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Ardisia japonica (Thunb.) Blume and Lespedeza cuneata G. Don may treat chronic obstructive pulmonary disease by targeting HK2 and PTAFR
Published 2025-05-01“…Additionally, functional analysis, immune factor profiling, molecular docking, and reverse transcription-polymerase chain reaction (RT-qPCR) were performed.ResultsHK2 and PTAFR emerged as critical genes for COPD treatment, exhibiting significantly elevated expression in COPD samples. RT-qPCR confirmed the significantly higher expression of HK2 (P = 0.0425) in COPD samples. …”
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242
An updated meta-analysis of the association between tumor necrosis factor-α -308G/A polymorphism and obstructive sleep apnea-hypopnea syndrome.
Published 2014-01-01“…Further studies with larger sample should be performed to confirm our findings.…”
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The D-Dimer to Albumin Ratio Could Predict Hospital Readmission Within One Year in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Published 2024-11-01“…Baseline data and blood samples were collected, and patients were followed up for one year after inclusion. …”
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245
Primary care for people with severe mental illness and comorbid obstructive airways disease: a qualitative study of patient perspectives with integrated stakeholder feedback
Published 2022-03-01“…Objectives To explore patient and stakeholder perspectives on primary respiratory care for people with severe mental illness (SMI) and comorbid obstructive airways disease (OAD).Design Qualitative, semistructured qualitative interviews were undertaken with a purposive sample of people with a diagnosis of SMI (bipolar illness, schizophrenia, affective disorder with psychosis) and comorbid asthma or chronic obstructive pulmonary disease. …”
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Effect of Qingjin Huatan decoction on pulmonary function and inflammatory mediators in stable chronic obstructive pulmonary disease: A systematic review and meta-analysis.
Published 2025-01-01“…<h4>Background</h4>The inflammatory response is the main pathophysiological basis of stable chronic obstructive pulmonary disease (COPD). It is a key factor that leads to frequent exacerbations and disease progression. …”
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The longitudinal impact of low-dose morphine on diurnal cortisol profiles in people with chronic breathlessness and chronic obstructive pulmonary disease (COPD): an exploratory stu...
Published 2025-04-01“…Methods This was an optional, hypothesis-generating sub-study embedded in a multi-site, randomised, double-blind, placebo-controlled trial (RCT) of regular, low-dose morphine for chronic breathlessness and chronic obstructive pulmonary disease. In a blinded dose-increment algorithm by week three, doses were 0 mg-32 mg. …”
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Bacterial Profiles and Antibiotic Resistance in Chronic Obstructive Pulmonary Disease Patients with Exacerbation and Type 2 Respiratory Failure at Adam Malik General Hospital
Published 2024-09-01“…Abstract Chronic obstructive pulmonary disease (COPD) is a prevalent condition characterized by persistent respiratory symptoms and airflow limitation. …”
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Validating the pathogenic mechanism of chronic obstructive pulmonary disease induced by negative emotions via Mendelian randomization and traditional Chinese medicine theory of emo...
Published 2025-06-01“…Objective: We employed Mendelian randomization (MR) to test the traditional Chinese medicine (TCM) theory of emotional pathogenesis concept and explore the causal relationship between negative emotions and chronic obstructive pulmonary disease (COPD). Methods: Data of negative emotions, bronchitis, emphysema, and C-reactive protein (CRP) levels were downloaded from genome-wide association study (GWAS) public database for a two-sample MR analysis. …”
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Internal Medicine Resident’s Knowledge and Attitudes towards Obstructive Sleep Apnoea in Riyadh City, Saudi Arabia: A Survey-based Cross-sectional Study
Published 2025-01-01“…Participants were chosen using a convenience sampling technique. An online questionnaire was sent to each potential participant via E-mail or WhatsApp, including a previously validated Obstructive Sleep Apnoea Knowledge and Attitude questionnaire. …”
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Experiences of Home‐Based Pulmonary Rehabilitation With mHealth and Centre‐Based Pulmonary Rehabilitation in People With Chronic Obstructive Pulmonary Disease: A Qualitative Study...
Published 2025-04-01“…Methods Convenience then purposive sampling was used to recruit participants enrolled in a randomised controlled trial after completion or withdrawal from either m‐PR or CB‐PR. …”
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Tele-Pulmonary Rehabilitation and Mediterranean-like Lifestyle, Adjunctively to Continuous Positive Airway Pressure in Obstructive Sleep Apnea Patients: Effects in Fitness and Oxid...
Published 2024-09-01“…Obstructive sleep apnea (OSA), often overlooked by clinicians, may lead to negative outcomes if left untreated. …”
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Prevalence of chronic obstructive pulmonary disease in high-risk populations at low, intermediate, high altitudes: a population based cross-sectional study in Yunnan Province, Chin...
Published 2025-03-01“…Abstract Background Chronic obstructive pulmonary disease (COPD) represents a significant public health challenge. …”
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Bacterial Isolates and Antibacterial Resistance Patterns in a Patient with Acute Exacerbation of Chronic Obstructive Pulmonary Disease in a Tertiary Teaching Hospital, Southwest Et...
Published 2022-01-01“…Introduction. Chronic obstructive pulmonary disease (COPD) is a major cause of chronic morbidity and mortality worldwide. …”
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Placement of a self-expandable metallic stent as a bridge to surgery for large bowel obstruction induced by effective neoadjuvant therapy: report of three cases
Published 2018-08-01“…Abstract Background Self-expandable metallic stent placement is a widely performed palliative procedure or bridge to surgery for obstructive colorectal cancer. However, the feasibility of this procedure for large bowel obstruction induced by effective neoadjuvant therapy is unclear. …”
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Enhancing Adherence to Continuous Positive Airway Pressure Therapy in Patients With Obstructive Sleep Apnea Using Augmented Reality: Protocol for a Randomized Controlled Trial
Published 2025-05-01“… BackgroundContinuous positive airway pressure (CPAP) therapy is the gold standard treatment for treating obstructive sleep apnea (OSA). However, patient adherence to CPAP therapy remains a critical challenge, with many individuals finding it difficult to maintain consistent use due to discomfort, lack of understanding, or perceived inconvenience. …”
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A machine learning framework for short-term prediction of chronic obstructive pulmonary disease exacerbations using personal air quality monitors and lifestyle data
Published 2025-01-01“…Abstract Chronic Obstructive Pulmonary Disease (COPD) is a heterogeneous disease with a variety of symptoms including, persistent coughing and mucus production, shortness of breath, wheezing, and chest tightness. …”
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Relationship between gene polymorphisms of pulmonary alveolar surfactant protein D and genetic susceptibility in elderly Han patients with chronic obstructive pulmonary disease in...
Published 2025-07-01“…The blood samples were collected to obtain SP-D gene polymorphisms (frequencies of alleles and genotypes at rs721917 and rs2245121 loci) by PCR restriction fragment length polymorphism. …”
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