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  1. 141

    Modeling the herpes zoster disease burden and its potential health impact on older adults >50 years of age in Brazil by Ariel Bardach, Jamile Ballivian, Ângela Maria Bagattini, Michelle Quarti Machado da Rosa, Max Moura de Oliveira, Jorge A. Gomez, Agustín Casarini

    Published 2025-12-01
    “…As the Brazilian healthcare system constitutes a complex combination of public-private financing, estimating the true impact of HZ is challenging. The objective was to ascertain the disease burden of HZ and estimate its attributable cost in older adults aged ≥50 y who are users of public and private health services. …”
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    Mediators of change in a condensed online exposure-based intervention provided soon after trauma: insights from a randomised controlled trial by Maria Bragesjö, Filip K. Arnberg, Erik Andersson

    Published 2024-12-01
    “…This study aimed to address this gap by analysing weekly data from a randomised trial involving a 3-week therapist-guided online intervention based on prolonged exposure compared to a waiting-list control group.Method: The objective was to investigate whether changes in each of the four subscales of the Posttraumatic Stress Disorder Checklist, fifth version (PCL-5; i.e. intrusions, avoidance behaviours, negative alternations in cognitions and hyperarousal) during the three-week intervention period mediated subsequent improvements in other post-traumatic stress symptoms at the controlled 1-month follow-up. …”
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    Observational study on early pulmonary complications following emergency abdominal surgeries in a tertiary care hospital in West Bengal by Anirban Hazra, Yogesh Chauhan, Premangshu Ghosh, Riddhisundar Samanta, Mohan Pradhan, Subhabrata Das

    Published 2025-03-01
    “…The consequences of developing a PPC are serious with doubled health-care costs, longer hospital stays, and higher mortality rates when compared to elective surgery. Aims and Objectives: This study was done to estimate the incidence of early post-operative pulmonary complications, the influence of pre-existing pulmonary morbidity and related factors in the development of PPC; and the outcome of management of PPC. …”
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    Effectiveness, safety and costs of the FreeStyle Libre glucose monitoring system for children and adolescents with type 1 diabetes in Spain: a prospective, uncontrolled, pre-post s... by Lilisbeth Perestelo-Pérez, Amado Rivero-Santana, Cristina Valcárcel-Nazco, Yolanda Álvarez-Pérez, Pedro Serrano-Aguilar, Yolanda Ramallo-Fariña, Lidia García-Pérez, Miguel Angel García-Bello, Himar Gonzalez-Pacheco, Ariadna Campos Martorell, Amparo González Vergaz, Ana María Prado Carro, Anunciación Beisti Ortego, Atilano José Carcavilla Urqui, Cristina Amparo Del Castillo Villaescusa, Estela Gil Poch, Francisco Javier Arroyo Diez, Gemma Novoa Gómez, Isabel González Casado, Juncal Martínez Ibáñez, Laura Cuadrado Piqueras, Leticia Reis Iglesias, Lucia Garzón Lorenzo, Luis Salamanca Fresno, María Asunción Martínez Brocca, María Aurea Rodríguez Blanco, María Del Mar Martínez López, María Jesús Ferreiro Rodríguez, María Ruiz del Campo, Nerea Itza Martín, Patricia García Navas, Rebeca García García

    Published 2023-12-01
    “…Objectives This study aimed to evaluate the effectiveness, safety and costs of FreeStyle Libre (FSL) glucose monitoring system for children and adolescents with type 1 diabetes mellitus (T1DM) in Spain.Design Prospective, multicentre pre-post study.Setting Thirteen Spanish public hospitals recruited patients from January 2019 to March 2020, with a 12-month follow-up.Participants 156 patients were included.Primary and secondary outcome measures Primary: glycated haemoglobin (HbA1c) change. …”
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  14. 154

    Feasibility study of using the PREDICT kidney tool for patients with localised renal cell carcinoma by Panayiotis Laouris, Chiara Re, Georgia Stimpson, Axel Bex, James Blackmur, Alexander Laird, Carley Batley, Grant D. Stewart, Hannah Harrison, Juliet A. Usher‐Smith

    Published 2025-04-01
    “…Study Design A multicentre, prospective feasibility study of incorporating the PREDICT Kidney risk communication tool into the first follow‐up consultation for localised RCC patients post‐surgery. Endpoints Patient uptake into the study, completeness of data collection, consultation duration, the acceptability of the tool to both patients and clinicians, clinician adherence to the study “best‐practice” guide, variability in tool usage across clinicians and sites and patient‐level clinical outcomes including subjective and objective comprehension of risk of recurrence and follow‐up, perceived risk of cancer recurrence, risk conviction, satisfaction with the information provided on risk of recurrence and follow‐up, and fear of cancer recurrence. …”
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  15. 155

    Expanding two-way texting for post-operative follow-up: A cost analysis of the implementation and scale-up in routine voluntary medical male circumcision settings in South Africa. by Molly Unsworth, Isabella Fabens, Geoffrey Setswe, Khumbulani Moyo, Jacqueline Pienaar, Calsile Makhele, Motshana Phohole, Nelson Igaba, Sizwe Hlongwane, Maria Sardini, Tracy Dong, Monisha Sharma, Hannock Tweya, Felex Ndebele, Marrianne Holec, Caryl Feldacker

    Published 2025-01-01
    “…A randomized controlled trial (RCT) using our fee-free, open-source, two-way texting (2wT) approach showed that males could independently monitor their healing with nurse-led telehealth support. 2wT was more cost-effective than routine visits for quality post-operative monitoring. The objectives of this study were:1) assess the additive cost of 2wT vs. standard of care (SoC) during a stepped wedge design (SWD) expansion trial; 2) determine the cost of augmenting 2wT implementation with dedicated personnel during peak VMMC periods; and 3) estimate the cost savings of 2wT from the payer perspective if scaled in routine settings. …”
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  16. 156

    PHF19 before and post induction treatment possess favorable potency of reflecting treatment response to protease inhibitors, event-free survival, and overall survival in multiple m... by Hongyu An, Shiming Chen, Xin Zhang, Shandong Ke, Jinyong Ke, Yalan Lu

    Published 2024-12-01
    “…This study intended to explore the potency of PHF19 at baseline and post induction treatment in estimating treatment response to protease inhibitors and survival in MM patients.Methods This retrospective study screened 69 MM patients who received protease inhibitors with bone marrow (BM) samples available at both baseline and post induction treatment. …”
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  17. 157

    A Statistical Framework to Detect and Quantify Operator-Learning Curves in Medical Device Safety Evaluation by Ssemaganda HC, Davis SE, Govindarajulu US, Koola JD, Mao J, Westerman DM, Perkins AM, Speroff T, Ramsay CR, Sedrakyan A, Ohno-Machado L, Matheny ME, Resnic FS

    Published 2025-07-01
    “…This study warrants subsequent framework validation by using real-world clinical datasets.Keywords: post-market surveillance, generalized additive models, Levenberg-Marqualdt algorithm, learning curve…”
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    A study of the relationship between Bispectral index and age-adjusted minimum alveolar concentration during the maintenance phase of general anesthesia in elective surgery by Nishant Kumar, Gunjan Bansal, Aruna Jain

    Published 2024-11-01
    “…Background and Aims: Bispectral index (BIS) and minimum alveolar concentration (MAC) are commonly used to monitor the depth of anesthesia. The objective was to study the correlation between BIS and age-adjusted minimum alveolar concentration (aaMAC) during the maintenance phase of anesthesia. …”
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