Shortening duration of untreated illness in young people with first episode eating disorders: protocol of a randomised controlled feasibility trial of a smartphone friendly multi-m... by Luiza Grycuk, Dina Monssen, Molly R. Davies, Helen Sharpe, Karina L. Allen, Vibhore Prasad, Rachel Potterton, Priya Popat, Victoria A. Mountford, Sheryllin McNeil, Vanessa Lawrence, Nina Grant, Kimberley A. Goldsmith, Danielle Glennon, Sarah Byford, Amy Brown, Ulrike Schmidt

“…Methods We will carry out a randomised controlled feasibility trial comparing the FREED-M tool with a control intervention where individuals are sign-posted to an ED charity website. The objectives of the proposed trial are to establish/estimate: (a) attrition rates at follow-up (primary feasibility outcome); (b) participant recruitment; (c) intervention uptake, completion rates and acceptability; (d) intervention effect sizes and standard deviations for outcomes to inform the sample size calculation for a large-scale randomised controlled trial (RCT); (e) stakeholder views on the intervention. …”
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How well do coverage surveys and programmatically reported mass drug administration coverage match? Results from 214 mass drug administration campaigns in 15 countries, 2008–2017 by Karsor Kollie, Nebiyu Negussu, Scott D Nash, Donal Bisanzio, Fiona M Fleming, Pamela S Mbabazi, Richard Reithinger, Kathryn L Zoerhoff, Katherine Gass, John Kraemer, Brian B Fuller, Lynsey Blair, Roland Bougma, Aboulaye Meite, Bizuayehu Gashaw, Nana-Kwadwo Biritwum, Jean Frantz Lemoine, Helena Ullyartha Pangaribuan, Eksi Wijayanti, Clara Fabienne Rasoamanamihaja, Lazarus Juziwelo, Square Mkwanda, Pradip Rimal, Issa Gnandou, Bocar Diop, Ameyo Monique Dorkenoo, Rachel Bronzan, Edridah Muheki Tukahebwa, Fatima Kabole, Violetta Yevstigneyeva, Lauren Courtney, Joseph Koroma, Egide Endayishimye, Margaret C Baker

“…Surveyed treatment coverage came from post-MDA community-based coverage evaluation surveys, which were conducted as per standardised WHO recommended methodology.Results Coverage estimates using routine reporting and surveys gave the same result in terms of whether the minimum coverage threshold was reached in 72% of the MDAs surveyed in the Africa region and in 52% in the Asia region. …”
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Clinical Outcomes and Healthcare Utilization in Patients Receiving Maintenance Dialysis After the Onset of the COVID-19 Pandemic in Ontario, Canada by Kyla L. Naylor, Nivethika Jeyakumar, Yuguang Kang, Stephanie N. Dixon, Amit X. Garg, Ahmed Al-Jaishi, Peter G. Blake, Rahul Chanchlani, Longdi Fu, Ziv Harel, Jane Ip, Ahbijat Kitchlu, Jeffrey C. Kwong, Gihad Nesrallah, Matthew J. Oliver, Therese A. Stukel, Ron Wald, Matthew Weir, Kevin Yau

“…Methods: We used Poisson generalized estimating equations to model pre-COVID outcome trends and used these to predict post-COVID outcomes and to estimate the relative change (i.e., the ratio of the observed to the expected rate). …”
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基于患者指南的健康教育对缺血性卒中患者二级预防用药依从性的影响(Effects of Health Education Based on the Patient Version of Guidelines on Medication Compliance in Secondary Prevention among Patients with Ischemic... by 王瑞香1，朱思静1，梁嘉贵2，晏利姣3，蓝远霞1 (WANG Ruixiang1, ZHU Sijing1, LIANG Jiagui2, YAN Lijiao3, LAN Yuanxia1 )

“…The scores of disease knowledge and post-intervention nursing satisfaction of the two groups were collected before and after intervention. …”
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Clinical Outcomes and Health Care Utilization in Patients with Advanced Chronic Kidney Disease not on Dialysis After the Onset of the COVID-19 Pandemic in Ontario, Canada by Carol Wang, Yuguang Kang, Stephanie N. Dixon, Nivethika Jeyakumar, K. Scott Brimble, Amit X. Garg, Peter G. Blake, Therese A. Stukel, Matthew J. Oliver, Ahmed Al-Jaishi, Kristin K. Clemens, Longdi Fu, Jane Ip, Susan McKenzie, Louise Moist, Amber O. Molnar, Flory Muanda-Tsobo, Marian Reich, Pavel Roshanov, Samuel A. Silver, Ronald Wald, Matthew A. Weir, Kevin Yau, Ann Young, Kyla L. Naylor

“…Poisson generalized estimating equations were used to predict post-COVID-19 patient outcomes and health utilization based on pre-COVID trends, estimating relative changes between the observed and expected outcomes. …”
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Competition in the product market, CEO's power, and readability of financial reports by Shokrollah Khajavi, Soraya Weysihesar, Ali Asghar Dehghani Saadi

“…Regarding the time dimension of the data, it is retrospective and post-event. To achieve the objectives of the research, 105 companies listed on the Tehran Stock Exchange were examined for the period from 2016 to 2022. …”
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Pramipexole in addition to mood stabilisers for treatment-resistant bipolar depression: the PAX-BD randomised double-blind placebo-controlled trial by Hamish McAllister-Williams, Nicola Goudie, Lumbini Azim, Victoria Bartle, Michael Berger, Chrissie Butcher, Thomas Chadwick, Emily Clare, Paul Courtney, Lyndsey Dixon, Nichola Duffelen, Tony Fouweather, William Gann, John Geddes, Sumeet Gupta, Beth Hall, Timea Helter, Paul Hindmarch, Eva-Maria Holstein, Ward Lawrence, Phil Mawson, Iain McKinnon, Adam Milne, Aisling Molloy, Abigail Moore, Richard Morriss, Anisha Nakulan, Judit Simon, Daniel Smith, Bryony Stokes-Crossley, Paul Stokes, Andrew Swain, Zoë Walmsley, Christopher Weetman, Allan H Young, Stuart Watson

“…Secondary objectives To examine the impact of pramipexole on mood and anxiety symptoms, psychosocial function (over 48 weeks), and pleasure (over 12 weeks). …”
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The clinical utility and safety of biomarker-guided immunosuppression withdrawal in liver transplantation: the LIFT prospective RCT by Julien Vionnet, Rosa Miquel, Juan G Abraldes, Juan-Jose Lozano, Pablo Ruiz, Miquel Navasa, Aileen Marshall, Frederik Nevens, William Gelson, Joanna Leithead, Steven Masson, Elmar Jaeckel, Richard Taubert, Phaedra Tachtatzis, Dennis Eurich, Kenneth Simpson, Eliano Bonaccorsi-Riani, James Ferguson, Alberto Quaglia, Maria Elstad, Marc Delord, Abdel Douiri, Alberto Sánchez-Fueyo

“…In a study completed in 2012, it was possible to identify liver transplant patients who had developed tolerance with high precision by conducting a genetic test in a liver biopsy. The objective of the current clinical trial was to validate this test of tolerance. …”
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Perioperative Blood Transfusion Is Associated with Worse Survival in Patients Undergoing Radical Cystectomy after Neoadjuvant Chemotherapy for Muscle-Invasive Bladder Cancer by Tessa Ladner, Anna J. Black, Homayoun Zargar, Jonathan L. Wright, Andrew C. Thorpe, Todd M. Morgan, Jeff M. Holzbeierlein, Michael S. Cookson, Niels-Erik Jacobsen, Adrian S. Fairey, Colin P. N. Dinney, Maria C. Mir, Laura-Maria Krabbe, Jeffrey S. Montgomery, Nikhil Vasdev, Evan Y. Yu, Evanguelos Xylinas, Andrew J. Stephenson, Jay B. Shah, Siamak Daneshmand, Kamran Zargar-Shoshtari, Philippe E. Spiess, Laura S. Mertens, Bas W. G. van Rhijn, Petros Grivas, Wassim Kassouf, Marc A. Dall’Era, Srikala S. Sridhar, Jonathan S. McGrath, Jonathan Aning, Shahrokh F. Shariat, Trinity J. Bivalacqua, Scott A. North, Daniel A. Barocas, Yair Lotan, Peter C. Black

“…<b>Objectives:</b> Perioperative blood transfusion (PBT) has been associated with worse survival after radical cystectomy (RC) in patients with muscle-invasive bladder cancer (MIBC). …”
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Enhanced recovery pathway for older people with hip fracture and cognitive impairment in acute hospitals: the PERFECTED research programme including an RCT by Chris Fox, Simon P Hammond, Lee Shepstone, Fiona Poland, Catherine Henderson, Tamara Backhouse, Bridget Penhale, Simon Donell, Martin Knapp, Douglas Lewins, Alasdair MacLullich, Martyn Patel, Opinder Sahota, Toby O Smith, Justin Waring, Jane L Cross

“…Data suggest that sources yielded inconsistent estimates for inpatient days and for emergency department visits but more consistent estimates for outpatient attendances. …”
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Robotic ileal ureter replacement for panureteral stricture disease: a step-by-step guide by Emily Ji, Devin Boehm, Jonathan Rosenfeld, Rebecca Arteaga, Jaewoo Kim, Aidan Raikar, Ziho Lee

“…Objective: Traditionally, open ileal ureter replacement (IUR) was a reconstructive option for patients with long-segment ureteral strictures not amenable to excision and primary anastomosis. …”
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SURVIVAL OUTCOMES OF AUTOLOGOUS STEM CELL TRANSPLANTATION IN LYMPHOMA PATIENTS by Elif Yıldız, Güven Çetin, Özge Pasin

“…Objective: Lymphomas, a diverse group of hematological malignancies, vary significantly in their prognosis, survival outcomes and response to treatment. …”
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Advancing dementia care: a review of Italy’s public health response within the WHO Global Action Plan and European strategies by Giancarlo Logroscino, Daniele Imperiale, Nicola Vanacore, Nicola Veronese, Giorgio Fumagalli, Cristina Basso, Federica Asta, Marco Canevelli, Eleonora Lacorte, Anna Maria Bargagli, Angela Giusti, Ilaria Bacigalupo, Guido Bellomo, Ilaria Palazzesi, Paola Piscopo, Emanuela Salvi, Valerio Zaccaria, Francesca Zambri, Martina Valletta, Massimo Corbo, Teresa Di Fiandra, Alessio Crestini, Francesco Saverio Mennini, Rosella Saulle, Alessandra Lombardi, Antonio Guaita, Luciano Sagliocca, Rosa Liperoti, MARCO TRABUCCHI, Maria Cotelli, Carlo Gabelli, Gianfranco Spalletta, Carlo Petrini, Vincenza Frisardi, Alice Fauci, Marcello Giordano, Luca Vignatelli, Luciana Riva, Camillo Marra, Francesco Nonino, Antonio Ancidoni, Simone Salemme, Domitilla Marconi, Sara Maria Pani, Nicoletta Locuratolo, Flavia Lucia Lombardo, Elisa Fabrizi, Francesco Sciancalepore, Patrizia Lorenzini, Alice Paggetti, Francesco Della Gatta, Annachiara Di Nolfi, Vittorio Palermo, Paolo Sciattella, Chiara Bini, Caterina Bianca Neve Aurora Bianchi, Fiammetta Landoni, Maria Assunta Giannini, Stefano Sensi, Cristina Lupinetti, Valeria Panetta, Antonio Matera, Francesca Lubian, Carla Melani, Gennarina Arabia, Maria Pompea Bernardi, Annarita Greco, Annalisa Di Palma, Andrea Fabbo, Federica Boschi, Antonino Riolo, Antonio Zaccardi, Antonio Mastromattei, Silvia Scalmana, Ernesto Palummeri, Elisa Lidonnici, Alessandro Amorosi, Lorenzo Blandi, Filippo Masera, Fabio Izzicupo, Alfonso Di Costanzo, Carla Severino, Patrizia Spallino, Piero Secreto, Elena Memeo, Stefano Piras, Serena Meloni, Tommaso Piccoli, Sara Madrigali, Antonella Notarelli, Micaela Gilli, Anna Laura Spinelli, Nando Scarpelli, Monica Seganfreddo, Alessandra Caci, Amalia Cecilia Bruni, Francesco Mazzoleni, Alessandro Pirani, Massimiliano Massaia, Luisa Bartorelli, Susanna Cipollari, Gabriella Porro, Mario Possenti, Manlio Matera, Patrizia Spadin, Paolo Caffarra, Andrea Capasso, Maria Pia Cozzari, Sabina Gainotti, Giuseppe Gambina, Marina Michela Gasparini, Andrea Stracciari, Gilda Losito, Elena Rendina, Federica Francescone, Francesca Galeotti, Teresa Di Fiandra, Flaminia Camilli, Elena Carbone, Giulia Carnevale, Daniela Coclite, Benedetta Contoli, Francesco Della Gatta, Annachiara Di Nolfi, Eugenio Distaso, Ylenia Druda, Sabrina Esposito, Francesco Giaquinto, Flavia L. Lombardo, Gabriella Martelli, Maria Masocco, Fabio Matascioli, Alberto Milanese, Valentina Minardi, Sandra Morelli, Antonello Napoletano, Maria Cristina Porrello, Giulia Remoli, Roberto Rivabene, Paola Scardetta, Roberta Vaccaro, Petronilla Battista, Consuelo Borgarelli, Chiara Cerami, Annalisa Chiari, Alfredo Costa, Alessandra Dodich, Elisa Faè, Elisa Favaretto, Lidia Fubini, Monica Gandelli, Donata Gollin, Claudio Ivaldi, Alessandro Lanzoni, Valentina Lavermicocca, Margherita Lazzarino, Giacomo Menabue, Maria Angela Molinari, Alessia Morelli, Fabrizio Piazza, Anna Peruzzi, Clara Ricci, Stefano Russo, Davide Zenaro, Alessandra Ceccarini, Scilla Pizzarelli, Zuzana Mitrova, Salvatore De Masi

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CLINICAL PRESENTATION AND OUTCOMES OF PATIENTS WITH MYELODYSPLASTIC SYNDROME INTRODUCTION by Jehanzeb Ur Rehman

“…Objective: Myelodysplastic Syndrome (MDS) is a clonal hematopoietic disorder that is characterized by dysplasia along with anaemia, thrombocytopenia or neutropenia and a risk of progression to Acute Myeloid Leukaemia (AML). …”
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Bisoprolol for patients with chronic obstructive pulmonary disease at high risk of exacerbation: the BICS RCT by Graham Devereux, Seonaidh Cotton, Mintu Nath, Nicola McMeekin, Karen Campbell, Rekha Chaudhuri, Gourab Choudhury, Anthony De Soyza, Shona Fielding, Simon Gompertz, John Haughney, Amanda Lee, Graeme MacLennan, Alyn Morice, John Norrie, David Price, Philip Short, Jorgen Vestbo, Paul Walker, Jadwiga Wedzicha, Andrew Wilson, Olivia Wu, Brian Lipworth

“…Results In total, 519 participants were recruited and randomised. Four post-randomisation exclusions left 259 in the bisoprolol group and 256 in the placebo group. …”
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Evaluation of prognostic models to improve prediction of metastasis in patients following potentially curative treatment for primary colorectal cancer: the PROSPECT trial by Vicky Goh, Susan Mallett, Manuel Rodriguez-Justo, Victor Boulter, Rob Glynne-Jones, Saif Khan, Sarah Lessels, Dominic Patel, Davide Prezzi, Stuart Taylor, Steve Halligan

“…Objectives Our primary objective was to improve prediction of outcomes from colorectal cancer by developing a multivariable prognostic model of disease-free survival. …”
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Contemporary manifestations of patriotism with particular information on social media by Julia Nowicka

“…Objectives Identification of contemporary forms of Polish patriotism. …”
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Ivacaftor–tezacaftor–elexacaftor, tezacaftor–ivacaftor and lumacaftor–ivacaftor for treating cystic fibrosis: a systematic review and economic evaluation by Steven J Edwards, Benjamin G Farrar, Kate Ennis, Nicole Downes, Victoria Wakefield, Isaac Mackenzie, Archie Walters, Tracey Jhita

“…The clinical effectiveness and safety of CFTR modulator combination therapies has been studied in clinical trials, and through real-world data collection, notably through a data collection agreement between the National Institute for Health and Care Excellence (NICE), the UK Cystic Fibrosis Trust, Vertex Pharmaceuticals (Boston, MA, USA), NHS England and NHS Improvement. Objectives The objective of this research is to compare the clinical effectiveness and cost-effectiveness of LUM/IVA, TEZ/IVA and ELX/TEZ/IVA with each other and with ECM for treating CF in England for people with at least one F508del mutation. …”
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The cost of delivering COVID-19 vaccines in four districts in Malawi by Anika Ruisch, Simon Ntopi, Ishani Mathur, Maeve Conlin, Anna McCaffrey, Damian G. Walker, Christian Suharlim

“…This study has two objectives, firstly to estimate the costs of delivering COVID-19 vaccine delivery using primary data collected in Malawi, and secondly comparing these estimates to modeled estimates based on secondary data, to contribute to a growing evidence base on the cost of the COVID-19 vaccination delivery in LICs. …”
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Optimising neonatal services for very preterm births between 27+0 and 31+6 weeks gestation in England: the OPTI-PREM mixed-methods study by Thillagavathie Pillay, Oliver Rivero-Arias, Natalie Armstrong, Sarah E Seaton, Miaoqing Yang, Victor L Banda, Kelvin Dawson, Abdul QT Ismail, Vasiliki Bountziouka, Caroline Cupit, Alexis Paton, Bradley N Manktelow, Elizabeth S Draper, Neena Modi, Helen E Campbell, Elaine M Boyle

“…Workstream 3: (a) Cost of neonatal care provided for very preterm babies born at 27–31 weeks gestation in neonatal intensive care unit and local neonatal unit in England within the National Health Service setting Objective To estimate neonatal costs to hospital discharge for very preterm babies born at 27–31 weeks gestation in NICU and LNU. …”
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