Thrombocytosis and bleeding in myeloproliferative neoplasms: exploring clinical diversity and risk of acquired von Willebrand syndrome—insights from a UK center by Giulia Simini, Andrew Innes, Saravanan Vinayagam, Golzar Mobayen, Nilanthi Karawitage, Simone Claudiani, Zain Odho, Mike Laffan, Deepa J. Arachchillage

“…Platelet count may have a direct link to these complications. Objectives: To share our MPN clinic’s experience with hemostatic testing and bleeding outcomes in patients with platelets ≥ 800 × 109/L. …”
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Stable improvement in hand muscle strength in incomplete spinal cord injury patients by long-term paired associative stimulation—a case series study by Kirsi Holopainen, Aleksandra Tolmacheva, Ines Bersch, Piia Haakana, Piia Haakana, Markus Pohjonen, Erika Kirveskari, Erika Kirveskari, Jari Arokoski, Anastasia Shulga, Anastasia Shulga

“…In muscles innervated by stimulated nerves, strength increased on average by 24.5% from pre- to post-conditions (p = 0.013). The achieved strength level was maintained for a minimum of 6 months after completing the stimulations. …”
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Interpersonal counselling for adolescent depression delivered by youth mental health workers without core professional training: the ICALM feasibility RCT by Jon Wilson, Viktoria Cestaro, Eirini Charami-Roupa, Timothy Clarke, Aoife Dunne, Brioney Gee, Sharon Jarrett, Thando Katangwe-Chigamba, Andrew Laphan, Susie McIvor, Richard Meiser-Stedman, Jamie Murdoch, Thomas Rhodes, Carys Seeley, Lee Shepstone, David Turner, Paul Wilkinson

“…Early psychological interventions to meet growing demand with limited resources are crucial. Objectives The study aimed to explore the effectiveness and cost effectiveness of interpersonal counselling for adolescents by (1) assessing the feasibility and acceptability of trial procedures; (2) exploring the delivery of, and differences between, interpersonal counselling for adolescents and treatment as usual; (3) evaluating the extent of contamination of the control arm and if it should be mitigated against in a future trial; and (4) investigating whether the interval estimate of benefit of interpersonal counselling for adolescents over treatment as usual in depression post treatment includes a clinically significant effect. …”
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Determination of the optimal ejaculate concentration of a buffalo bull for successful semen cryopreservation by Krishna Bansal, Krishna Bansal, Dinesh Jhamb, Usha Yadav, Usha Yadav, Mamta Meel, Mamta Meel, Akanksha Gupta, Akanksha Gupta, Renu Bala, Meenakshi Virmani, Meeti Punetha, Dharmendra Kumar, Pradeep Kumar

“…The second objective was to evaluate the post-thaw sperm quality of ejaculates that initially met the criteria for cryopreservation. …”
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Evaluation of exo-long noncoding RNA MALAT1 in OSCC in comparison to dysplastic and normal: A cross-sectional study by Ramya Sekar, Selvaraj Jayaraman, VishnuPriya Veeraraghavan, Kalaiselvi Krishnamoorthy, Shubhra Chauhan Aramanai, Sathan Raj Natarajan

“…Objective: This study explores the role of MALAT1 as a valuable target for creating minimally-invasive diagnostic methods and personalized treatments in the management of OSCC. …”
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Contrasting Patterns of Raccoon (Procyon lotor) Spatial Population Genomics Throughout a Rabies Management Area in Eastern North America by Matthew W. Hopken, Clara P. Mankowski, Christine Thurber, Antoinette J. Piaggio, Kathleen M. Nelson, Richard B. Chipman, Zaid Abdo, Tore Buchanan, Ariane Massé, Amy T. Gilbert

“…We combined samples from an extensive raccoon tissue repository with a RADcapture panel of 1000 microhaplotype loci to conduct spatial genetic analyses of raccoon populations in eastern North America. Our objective was to estimate patterns of genetic diversity on the landscape that may inform raccoon rabies management. …”
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Development and validation of a prognostic model to predict relapse in adults with remitted depression in primary care: secondary analysis of pooled individual participant data fro... by Simon Gilbody, Dean McMillan, Bob Phillips, Kym I E Snell, Richard D Riley, David A Richards, Jaime Delgadillo, Shehzad Ali, Chris Salisbury, Lewis W Paton, Lucinda Archer, Peter A Coventry, Stephen Pilling, Andrew S Moriarty, Joshua E J Buckman, Nick Meader, Carolyn A Chew Graham

“…We lack evidence-based tools to estimate an individual’s risk of relapse after treatment in primary care, which may help us more effectively target relapse prevention.Objective The objective was to develop and validate a prognostic model to predict risk of relapse of depression in primary care.Methods Multilevel logistic regression models were developed, using individual participant data from seven primary care-based studies (n=1244), to predict relapse of depression. …”
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Specimen oriented intraoperative margin assessment in oral cavity and oropharyngeal squamous cell carcinoma by P. Horwich, C. MacKay, M. Bullock, S. M. Taylor, R. Hart, J. Trites, L. Geldenhuys, B. Williams, M. H. Rigby

“…Abstract Objective Evaluate the oncologic outcomes and cost analysis of transitioning to a specimen oriented intraoperative margin assessment protocol from a tumour bed sampling protocol in oral cavity (OCSCC) and oropharyngeal squamous cell carcinoma (OPSCC). …”
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Changes in unhealthy food consumption among vulnerable elementary-aged children in the United States during the COVID-19 pandemic: a serial cross-sectional analysis by Nivedhitha Parthasarathy, Nalini Ranjit, Ru-Jye Chuang, Christine Markham, Mike Pomeroy, Jacqueline Noyola, Deepali K. Ernest, Shreela V. Sharma

“…No significant interaction between time period and HSED was observed on either scale. However, the post-regression estimates from the adjusted interaction model showed a significant association between convenience/fast food consumption and HSED in pre- and mid-pandemic periods.ConclusionThe study highlights the nuances of socioeconomic dynamics on the diet behaviors of children from low-income families during a natural disaster.…”
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Relation between bone mineral density and oxidative stress in Egyptian patients with chronic kidney disease: a cross sectional study by Samah M. Akab, Hanaa Elsayed Abozeid, Seham A. Elazab, Sherien Abdallh Fathy Elazab, Noran ElBazzar, Eman Refaat Youness, Mohamed Ahmed Shahba, Hisham A. Orban, Hanaa Reyad Abdallah, Moushira Zaki

“…The investigation of this relation is of pronounced importance in decreasing the occurrence of osteoporosis among CKD cases. Objectives To evaluate the association between BMD and OS in CKD patients. …”
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One Health intervention for elimination of animal to human disease transmission of Anthrax in an endemic district of Odisha: A baseline and endline study by Dr. Debaprasad Parai, Mr. Matrujyoti Pattnaik, Dr. Hari Ram Choudhary, Dr Arun Kumar Padhi, Dr. Niranjana Sahoo, Dr. Sanghamitra Pati, Dr Debdutta Bhattacharya

“…Descriptive statistics were reported and logistic regression was performed to estimate the relationship between the variables and knowledge of anthrax. …”
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A systematic review of histopathological assessments in Peste des petits ruminants by Saira Awaz, Iram Maqsood, Hanif Ur Rahman, Baitullah Khan, Gul Muhammad, Imtiaz Ali Shah, Asima Azam, Ayesha Hidayat, Almas Faryal Nizam

“…Information were the authors and publication year, research methodology and histopathological results linked to PPR, factors influencing these outcomes (including treatment type, immunisation technique, and time post-infection), and the authors' conclusions and recommendations. …”
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Heart transplantation in patients undergoing extracorporeal cardiopulmonary resuscitation in in‑hospital cardiac arrest by V. N. Poptsov, E. A. Spirina, A. K. Solodovnikova, A. S. Epremyan, A. A. Kuznetsova, A. S. Ignatkina, G. B. Glinkin, S. A. Budagaev

“…Objective: to analyze heart transplant (HT) outcomes in patients who suffered cardiac arrest requiring extracorporeal cardiopulmonary resuscitation (ECPR) by peripheral veno-arterial extracorporeal membrane oxygenation (VA-ECMO). …”
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Bariatric Surgery in the United Kingdom: A Cohort Study of Weight Loss and Clinical Outcomes in Routine Clinical Care. by Ian J Douglas, Krishnan Bhaskaran, Rachel L Batterham, Liam Smeeth

“…Comprehensive evidence of the long-term effects of contemporary surgery on a broad range of clinical outcomes in large populations treated in routine clinical practice is lacking. The objective of this study was to measure the association between bariatric surgery, weight, body mass index, and obesity-related co-morbidities.…”
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Improving Mental Health and Well-Being Through the Paradym App: Quantitative Study of Real-World Data by Athina Marina Metaxa, Shaun Liverpool, Mia Eisenstadt, John Pollard, Courtney Carlsson

“…MethodsThis is a pre-post, single-arm evaluation of real-world data provided by users of the Paradym app. …”
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Comparison of Removal Characteristics of Organophosphorus Flame Retardants Using Ozone and UV-Based Advanced Oxidation Processes in the Downstream of Nakdong River by Woorim Lee, Changdong Seo, Jaedon Shin, Yunho Lee, Heejong Son

“…Objectives This study aimed to evaluate the removal efficiency of trace organic contaminants (TrOCs) in UVbased advanced oxidation processes (AOPs) as an alternative to the post-ozonation process in a drinking water treatment plant (DWTP) in the downstream of Nakdong River. …”
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Psychological distress among refugees in Germany: a cross-sectional analysis of individual and contextual risk factors and potential consequences for integration using a nationally... by Ana Nanette Tibubos, Lena Walther, Hannes Kröger, Thi Minh Tam Ta, Christian von Scheve, Jürgen Schupp, Eric Hahn, Malek Bajbouj

“…We estimated the prevalence of psychological distress in a large refugee population in Germany and assessed its association with host country factors amenable to policy intervention and integration indicators.Design A cross-sectional and population-based secondary analysis of the 2017 wave of the IAB-BAMF-SOEP refugee survey.Setting Germany.Participants 2639 adult refugees who arrived in Germany between 2013 and 2016.Main outcome measures Psychological distress involving symptoms of depression, anxiety and post-traumatic stress disorder was measured using the Refugee Health Screener-13.Results Almost half of the population surveyed (41.2% (95% CI: 37.9% to 44.6%)) was affected by mild, moderate or severe levels of psychological distress. 10.9% (8.4% to 13.5%) of the population screened positive for severe distress indicative of an urgent need for care. …”
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Confronting food insecurity through agricultural interventions: the Farmer FIRST program in India by Purushothaman Venkatesan, Nilakandan Sivaramane, Ch Srinivasa Rao, Ramanujam Venkattakumar, Sethuraman Sivakumar, Palanisamy Mooventhan, Rajarshi Roy Burman, Bommu Kalyani, Lalitha Navya Challa

“…The results revealed that post-intervention of the FFP, cereal availability increased by 147.74% in the Northern Plain, while pulses recorded over 200% growth in three regions. …”
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High-BMI-related low back pain in China: a GBD-based observational study on sex–age trends and projections (1990–2021) by Juxiang Xu, Jianhua Li, Heqing Huang, Tiangao Lin, Zhiping Liao, Weibo Zhang, Jianing Wu, Fangchao Wu

“…Bayesian age–period cohort (BAPC) model was used to estimate the trend of burden of low back pain attributable to high BMI from 2022 to 2036. …”
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Clinical and cost-effectiveness of detailed anomaly ultrasound screening in the first trimester: a mixed-methods study by Jehan N Karim, Helen Campbell, Pranav Pandya, Edward C F Wilson, Zarko Alfirevic, Trish Chudleigh, Elizabeth Duff, Jane Fisher, Hilary Goodman, Lisa Hinton, Christos Ioannou, Edmund Juszczak, Louise Linsell, Heather L Longworth, Kypros H Nicolaides, Anne Rhodes, Gordon Smith, Basky Thilaganathan, Jim Thornton, Gillian Yaz, Oliver Rivero-Arias, Aris T Papageorghiou

“…The rarity of the conditions made estimation of longer-term maternal and infant costs and quality-adjusted life-years challenging, resulting in likely under-estimation of healthcare costs. …”
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