Exploratory GABAa-informed control network modulates hyperarousal brain dynamics in chronic insomnia by Liyong Yu, Liang Gong, Xiaoqin Chen, Yuqi He, Rong Li, Xiaojuan Hong, Qi Zhang, Siyi Yu

Get full text

HCF-1 as a key modulator of OGT function and O-GlcNAcylation in the liver by Vaibhav Kapuria, Ayushma, Winship Herr, Shilpi Minocha

Get full text

Research on Modulation Format Recognition for Underwater Visible Light Communication based on BiGRU by GAO Wendi, WANG Yunkai, XU Chi, XU Zengyi, CHI Nan

“…【Results】Experimental results demonstrate that under various transmission voltage conditions, the algorithm achieves recognition accuracy rates exceeding 96% for ten different Quadrature Amplitude Modulation (QAM) and Amplitude Phase Shift Keying (APSK) signal modulation formats, including 2QAM, 4QAM, 8QAM, 8APSK, 16QAM, 16APSK, 32QAM, 32APSK, 64QAM and 64APSK. …”
Get full text

Simultaneous TGF-β and GITR pathway modulation promotes anti-tumor immunity in glioma by Daniela Lorizio, Manuela Silginer, Julia Friesen, Alan L. Epstein, Michael Weller, Patrick Roth

“…Transforming growth factor (TGF)-β signaling drives tumor progression and prevents effective T cell activity. Notably, both regulatory T cells (Tregs) and effector T cells within glioblastoma and other tumors express high levels of the immune checkpoint receptor, glucocorticoid-induced tumor necrosis factor receptor (GITR), which modulates T cell activation and function. …”
Get full text

Muscle Type-Specific Modulation of Autophagy Signaling in Obesity: Effects of Caloric Restriction and Exercise by Fujue Ji, Jong-Hee Kim

Get full text

Modulation of Giant Magnetoimpedance Effect in Co-Based Amorphous Wires by Carbon-Based Nanocoatings by Zhen Yang, Jiabao Huang, Jingyuan Chen, Chong Lei

“…Our findings provide valuable insights into the modulation of GMI properties in Co-AWs, paving the way for their optimized application in advanced magnetic sensor technologies.…”
Get full text

Nitrogen Fertilization Shapes Soil Microbial Diversity and Ecosystem Multifunctionality by Modulating Soil Nutrients by Yaoquan Zhang, Zhuzhu Luo, Liangliang Li, Lili Nian, Lingling Li, Yining Niu, Renyuan He, Jiahe Liu

Get full text

Modulating mitochondria with natural extract compounds: from bench to clinical therapeutic opportunities for COPD by Qiao Wang, Ziling Zeng, Linlin Guo, Kent E. Williams, Yun Zhang, Yun Zhang, Hongmei Tang, Hang Hu, Hang Hu, Gang Qin, Kaijin Wang, Xing Wang

Get full text

Reticulospinal modulation of muscle activation and electromechanical coupling: evidence from the StartReact paradigm by Antonia Maria Eilfort, Antonia Maria Eilfort, Antonia Maria Eilfort, Linard Filli, Linard Filli, Linard Filli

“…EMD was defined as the time interval between EMG onset and movement initiation.ResultsOur results revealed faster and more pronounced muscle activation and movement performance in response to LAS compared to MAS. Notably, EMD was significantly reduced in LAS trials, suggesting that enhanced RS drive facilitates more rapid electromechanical coupling.DiscussionThese findings suggest that RS drive not only shortens muscular reaction times – characteristic of the StartReact effect - but also modulates muscle activation and movement dynamics in a way that accelerates the transition from muscle activation to movement. …”
Get full text

The RAE1-STOP1 module regulates ABA sensitivity in early seedlings of Arabidopsis by Yuqing Zhang, Min Huang, Yinyin Liu, Mengmeng Yang, Yuqi Hou, Chao-Feng Huang, Ning Ning Wang, Lei Li

Get full text

Vagus nerve modulates acute-on-chronic liver failure progression via CXCL9 by Li Wu, Jie Li, Ju Zou, Daolin Tang, Ruochan Chen, Yanjie Yin

“…Blocking CXCL9 and CXCR3 ameliorated liver inflammation and increased ACLF-associated mortality in ACLF mice with vagotomy. scRNA-seq revealed that hepatic macrophages served as the major source of CXCL9 in ACLF and were validated by immunofluorescence staining and flow cytometry analysis. Notably, the expression of CXCL9 in macrophages was modulated by vagus nerve-mediated cholinergic signaling. …”
Get full text

Slope Position Modulates Soil Chemical Properties and Microbial Dynamics in Tea Plantation Ecosystems by Limei Li, Lijiao Chen, Hongxu Li, Yuxin Xia, Houqiao Wang, Qiaomei Wang, Wenxia Yuan, Miao Zhou, Juan Tian, Baijuan Wang

Get full text

A cytidine deaminase-like protein modulates pyrimidine nucleotide homeostasis in Trypanosoma brucei by Ana Moro-Bulnes, Cristina Bosch-Navarrete, Pablo Antequera-Parrilla, Santiago Castanys, Antonio E. Vidal, Luis Miguel Ruiz-Pérez, Guiomar Pérez-Moreno, Dolores González-Pacanowska

“…Using RNA interference (RNAi) and overexpression approaches, we demonstrate that TbCDA-like modulates pyrimidine nucleotide pools, influencing both ribonucleotide and deoxyribonucleotide profiles. …”
Get full text

Intralayer/Interlayer Codoping Stabilizes Polarity Modulation in 2D Semiconductors for Scalable Electronics by Guitian Qiu, Lingan Kong, Mengjiao Han, Qian Zhang, Majeed Ur Rehman, Jianxian Yi, Lede Xian, Xiankai Lin, Aumber Abbas, Jiwei Chen, Yingjie Luo, Wenbo Li, Zhongchao Wei, Hongyun Meng, Xiuliang Ma, Qijie Liang

Get full text

BPM Proteins Modulate Heat Stress Response in <i>Arabidopsis thaliana</i> Seedlings by Sandra Vitko, Dunja Leljak-Levanić, Nataša Bauer, Željka Vidaković-Cifrek

“…Heat stress induced HSP70 and HSP90 in all seedlings but expression remained notably higher in <i>amiR-bpm</i> after recovery. …”
Get full text

CDK12 antagonizes a viral suppressor of RNAi to modulate antiviral RNAi in Drosophila by Liqin Zhang, Yu Liang, Jiayu Qin, Chen Liu, Mengwei Shang, Xiaoming Sun

Get full text

Fucoidan Modulates Osteoarthritis Progression Through miR-22/HO-1 Pathway by Tsung-Hsun Hsieh, Jar-Yi Ho, Chih-Chien Wang, Feng-Cheng Liu, Chian-Her Lee, Herng-Sheng Lee, Yi-Jen Peng

“…Fucoidan treatment restored HO-1 expression while reducing inducible nitric oxide synthase and matrix metalloproteinase levels in IL-1β-stimulated cells. Notably, this study revealed that fucoidan modulates the miR-22/HO-1 pathway, a previously uncharacterized mechanism in OA. …”
Get full text

Compost Tea Combined with Fungicides Modulates Grapevine Bacteriome and Metabolome to Suppress Downy Mildew by Giuliano Bonanomi, Giuseppina Iacomino, Ayoub Idbella, Giandomenico Amoroso, Alessia Staropoli, Andrea De Sio, Franco Saccocci, Ahmed M. Abd-ElGawad, Mauro Moreno, Mohamed Idbella

Get full text

The role of foliar endophytes in modulating southern corn rust severity: implications for biocontrol strategies by Lujia Yang, Lili Li, Yingying Song, Yongsheng Zhang, Jie Yang, Hongying Cui, Wenxiu Guo, Suhong Lv, Xingyuan Men

“…Current SCR management strategies prioritize genetic resistance and chemical control, but how foliar endophytic fungal communities modulate host susceptibility to P. polysora remains poorly understood. …”
Get full text

FLNA, a disulfidptosis-related gene, modulates tumor immunity and progression in colorectal cancer by Qiong Li, Renhong Huang, Lingling Lv, Haifeng Ying, Yuan Wu, YuQing Huang, Yuxi Li, Wen Ma, Xiaoshuang Liu, Qinghui Meng, Fengying Xing, Yan Shen, Lan Zheng

“…These findings suggest that modulating disulfidptosis in conjunction with immunotherapy may offer a novel treatment paradigm for CRC.…”
Get full text