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Exploring the Therapeutic and Gut Microbiota-Modulating Effects of Qingreliangxuefang on IMQ-Induced Psoriasis
Published 2025-04-01“…Changes in the gut microbiota were analyzed via 16SrDNA sequencing, and T cell subsets were assessed using flow cytometry.Results: Network pharmacology analysis suggested that QRLXF ameliorated psoriasis by modulating Th17 cell differentiation. Further experiments confirmed the anti-inflammatory effects and relief of psoriatic lesions in IMQ-induced mice. 16SrDNA sequencing revealed significant shifts in the gut microbiota, notably increases in Ligilactobacillus and Lactobacillus genera and decreases in Anaerotruncus, Negativibacillus, Bilophila, and Mucispirillum, suggesting a potential relationship between specific microbiota changes and Th17 cell differentiation.Conclusion: QRLXF alleviated psoriatic dermatitis by regulating Th17 cell responses and modifying gut microbiota profiles, highlighting its therapeutic potential for psoriasis treatment.Plain Language Summary: Psoriasis affects millions globally. …”
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102
Modulation of endogenous plasmalogens by genetic ablation of lysoplasmalogenase (Tmem86b) in mice
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103
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104
Hyperactive Repeating Fast Radio Bursts from Rotation-modulated Starquakes on Magnetars
Published 2025-01-01“…Our results show that the assumption that all FRBs are repeaters is compatible with our model. Notably, we find that hyperactive repeaters tend to have small magnetic inclination angles in order to hide their periodicity. …”
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105
Monolithic silicon nitride electro-optic modulator enabled by optically-assisted poling
Published 2025-04-01“…Abstract Electro-optic (EO) modulation is a key functionality to have on-chip. However, achieving a notable linear EO effect in stoichiometric silicon nitride has been a persistent challenge due to the material’s intrinsic properties. …”
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106
Application of biological modulator in broiler litter to control Salmonella Heidelberg E2
Published 2025-07-01“…Among the proposed strategies for the prevention of this pathogen, the application of biological modulators that act to reduce this pathogen is of particular importance. …”
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107
OTFS modulation exploration for robust 6G communications in high mobility scenarios
Published 2025-01-01“…Orthogonal Time-frequency-space (OTFS) modulation represents a pioneering advancement, tailored to the requirements of prospective sixth-generation (6G) wireless networks. …”
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108
Decellularized Adipose Matrix Rejuvenates Photoaged Skin through Immune Microenvironment Modulation
Published 2025-01-01“…Conclusion: DAM offers a novel therapeutic approach for skin rejuvenation by modulating the immune microenvironment, demonstrating notable clinical potential.…”
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109
Temperature Modulates Nutrient Metabolism and Antioxidative Fluctuations in <i>Riptortus pedestris</i>
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110
Integration of the vegetation phenology module improves ecohydrological simulation by the SWAT-Carbon model
Published 2025-04-01“…Although the Soil and Water Assessment Tool (SWAT) has been widely used for estimating hydrological cycles, its lack of integration with the phenology module has led to substantial uncertainties. In this study, we developed a process-based vegetation phenology module and coupled it with the SWAT-Carbon model to investigate the effects of vegetation dynamics on runoff in the upper reaches of the Jinsha River watershed in China. …”
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111
Chronic Stress Modulates Microglial Activation Dynamics, Shaping Priming Responses to Subsequent Stress
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112
Precipitation Patterns and Their Role in Modulating Nitrous Oxide Emissions from Arid Desert Soil
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113
Prodynorphin-expressing neurons in the ventromedial hypothalamus respond to the predatory odor and modulate defensive behaviors
Published 2025-09-01“…These findings indicate that PDYN-expressing neurons in the VMH are specifically tuned to detect threat stimuli and play a role in modulating defensive behaviors.…”
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114
Characterization of Cost-Saving Monofacial PERC Module under Field Conditions in South Korea
Published 2023-01-01“…This study investigated the performance of a monofacial module employing a cost-saving bifacial cell installed at a carport in South Korea. …”
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115
Modulation by NPY/NPF-like receptor underlies experience-dependent, sexually dimorphic learning
Published 2025-01-01“…Transcriptomic and behavioral analysis revealed that the neuropeptide receptor npr-5, an ortholog of the mammalian NPY/NPF-like receptor, regulates male learning by modulating neuronal activity. Furthermore, we show the dependency of the males’ decision-making on their sexual status and demonstrate the role of npr-5 as a modulator of incoming sensory cues. …”
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116
Mixed signal modulation recognition method based on temporal depth residual shrinkage network
Published 2024-10-01“…There were three key modules in the model: a residual module, a shrinkage module, and a LSTM module. …”
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117
Theoretical study of XUV pulse shaping due to the modulation of an IR pulse in macroscopic systems
Published 2025-01-01“…Here, we examine the evolution of spectral reshaping driven by laser-imposed initial phase modulation during pulse propagation. We present an analytical framework that elucidates the physical mechanism underlying the emergence of these propagation-induced spectral structures, and validate it through numerical simulations. …”
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118
Deep Learning Image Compression Method Based On Efficient Channel-Time Attention Module
Published 2025-05-01“…However, traditional image compression methods face significant limitations in both quality and efficiency when applied to high-resolution imagery in such scenarios.To address these challenges, this paper proposes a deep learning–based image compression approach incorporating an Efficient Channel-Temporal Attention Module (ETAM). The ETAM module integrates Efficient Channel Attention (ECA-Net) and a Temporal Attention Module (TAM) to jointly enhance the extraction of spatial and temporal features, thereby improving compression efficiency and reconstruction quality.Experimental results demonstrate that the proposed method consistently outperforms both traditional and state-of-the-art deep learning–based compression techniques across multiple evaluation metrics, including PSNR, SSIM, and LPIPS. …”
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119
PCSK9 Modulates Macrophage Polarization-Mediated Ventricular Remodeling after Myocardial Infarction
Published 2022-01-01“…However, whether PCSK9 affects myocardial repair and the molecular mechanism of PCSK9 modulation of immune inflammation after AMI are not known. …”
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120
Rhizobium biostimulation of blackberry modulates survival pathways in Caenorhabditis elegans across biological kingdoms
Published 2025-07-01“…Inoculated plants exhibited a significant increase in yield and elevated levels of phenolic compounds, notably sanguiin H6 and cyanidin-3-O-glucoside, as quantified by HPLC-DAD-MS. …”
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