Extracellular vesicles of minimalistic Mollicutes as mediators of immune modulation and horizontal gene transfer by Theresa Maria Wagner, Sergi Torres-Puig, Thatcha Yimthin, Rossitza N. Irobalieva, Manfred Heller, Sabine Kaessmeyer, Thomas Démoulins, Jörg Jores

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Modulating the developing gut microbiota with 2’-fucosyllactose and pooled human milk oligosaccharides by Simone Renwick, Annalee Furst, Mikael Knip, on behalf of the DIABIMMUNE Study Group, Lars Bode, Jayne S. Danska, Emma Allen-Vercoe

“…Results Exposure to pHMOs induced significant shifts in both the microbial community composition and metabolic output, including an increased abundance of several genera, notably Bacteroides, and the production of health-associated metabolites. …”
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Asparagine endopeptidase regulates lysosome homeostasis via modulating endomembrane phosphoinositide composition by Linli Yao, GuangHui Zi, Miao He, Yuhong Xu, Lulu Wang, Baowei Peng

“…Our findings demonstrate that AEP regulates cellular autophagy by modulating lysosomal function through its control over endo/lysosomal PI3K activity. …”
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Mechanism of Cationic Peptide‐Induced Assembly of Gold Nanoparticles: Modulation of Electrostatic Repulsion by Benjamin Lam, Robert Ramji, Margaret Mullooly, Kristina D. Closser, Tod A. Pascal, Jesse V. Jokerst

“…Notably, histidine‐based and tyrosine‐based peptides could reversibly aggregate the AuNPs in response to the pH.…”
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Nitrogen source orchestrates pH modulation and secondary metabolism in Trichoderma harzianum by Stefania Vitale, Felice Salzano, Alessia Staropoli, Roberta Marra, David Turrà, Matteo Lorito, Francesco Vinale

“…This nitrogen-dependent pH modulation pattern was conserved across Trichoderma species, as demonstrated by parallel responses in T. asperellum. …”
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hsa-mir-483-3p modulates delayed breast cancer recurrence by Ok-Hyeon Kim, Tae Jin Jeon, Hana Kang, Eun Seo Chang, Soon Auck Hong, Min Kyoon Kim, Hyun Jung Lee

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CUEDC2 modulates cardiomyocyte oxidative capacity by regulating GPX1 stability by Zhao Jian, Bing Liang, Xin Pan, Guang Xu, Sai‐Sai Guo, Ting Li, Tao Zhou, Ying‐Bin Xiao, Ai‐Ling Li

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Hypoxia-induced RHCG as a key regulator in psoriasis and its modulation by secukinumab by Shun Guo, Qian Zhang, Yuan-jie Liu, Yun-yao Hu, Cong Liu, Hui Shen, Jia Liu

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Modulating the serine metabolism in human differentiated astrocytes: an integrated multi omics approach by Farida Tripodi, Elisa Maffioli, Silvia Sacchi, Valentina Rabattoni, Zoraide Motta, Claudia Bearzi, Gabriella Tedeschi, Gabriella Tedeschi, Loredano Pollegioni, Paola Coccetti

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Carnosine modulates Aβ-induced transcriptional aberrations in murine microglial cells by Veronica Rivi, Giuseppe Carota, Fabio Tascedda, Johanna M.C. Blom, Filippo Caraci, Cristina Benatti, Giuseppe Caruso

“…These results underscore carnosine's potential to modulate immune responses, enhance microglial activity, and provide neuroprotection in Aβ-induced conditions. …”
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Dietary macronutrients modulate the proteome of brown adipose tissue in males and their female offspring by Erin L. Macartney, Alistair M. Senior, Angela J. Crean, Lewin Small, Lou Ruffino, Tamara J. Pulpitel, Marcelo A. Nobrega, Romain Barrès, Stephen J. Simpson

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Nitrogen deposition modulates invasibility and stability of plant communities in microplastic-contaminated wetlands by Ziyi Wang, Mengxuan He, Zirui Meng, Jingqi Lang, Xueqiang Lu, Qing Xue, Limin Liang, Xunqiang Mo

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Urban underlying surface modulates summertime thunderstorm processes and associated lightning activities by T. Shi, T. Shi, Y. Yang, G. Lu, Z. Zheng, Y. Zi, Y. Tian, L. Liu, S. Lolli

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Therapeutic potential of Litsea cubeba essential oil in modulating inflammation and the gut microbiome by Liqiong Xia, Ran Li, Ran Li, Ting Tao, Ruimin Zhong, Haifang Du, Ziling Liao, Zhanghua Sun, Changqiong Xu, Changqiong Xu

“…However, unfettered and excessive inflammation can be instrumental in engendering a plethora of chronic ailments and detrimental health repercussions, notably within the gastrointestinal tract. Lipopolysaccharides (LPS) from bacteria are potent endotoxins capable of instigating intestinal inflammation through the disruption of the intestinal epithelial barrier and the stimulation of a pro-inflammatory immune response. …”
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Allosteric modulation of serotonin and dopamine transporters: New insights from computations and experiments by Hoang Nguyen, Mary Hongying Cheng, Ji Young Lee, Shaili Aggarwal, Ole Valente Mortensen, Ivet Bahar

“…They also provide a basis for designing allosteric modulators that may provide better control of specific interactions and cellular pathways, rather than indiscriminately inhibiting the transporter by targeting its orthosteric site.…”
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OSBPL3 modulates the immunosuppressive microenvironment and predicts therapeutic outcomes in pancreatic cancer by Qihui Sun, Xiaoqi Zhu, Qi Zou, Yang Chen, Tingting Wen, Tingting Jiang, Xiaojia Li, Fang Wei, Keping Xie, Jia Liu

“…Results Our risk prediction model, developed using machine learning algorithms, demonstrated high predictive accuracy across multiple datasets. Notably, the “rf” algorithm model showed an AUC of 1 in the training set and AUCs of 0.887 and 0.977 in two validation datasets. …”
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APOE4 reshapes the lipid droplet proteome and modulates microglial inflammatory responses by Cassi M. Friday, Isaiah O. Stephens, Cathryn T. Smith, Sangderk Lee, Diksha Satish, Nicholas A. Devanney, Sarah Cohen, Josh M. Morganti, Scott M. Gordon, Lance A. Johnson

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Epigenetic modulation elicits an NK cell-mediated immune response in urothelial carcinoma by Himani Kumari, Ciao-Ni Chen, Hsin-An Shih, Chih-Chieh Yeh, Tsung-Yu Tseng, Hsing-Fen Tsai, Jie Ting Low, Chin Pui Chan, Guan-Ling Lin, Wan-Hong Huang, Chao-Ling Yao, Steven Lin, Cheng-Huang Shen, Michael W. Y. Chan

“…This enhancement is attributed to the epigenetic activation of NKG2D ligands, notably through increased H3K27ac enrichment and reduced enrichment of H3K27me3 at the ULBP2 promoter region in UC cells. …”
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Chchd10: A Novel Metabolic Sensor Modulating Adipose Tissue Homeostasis by Xiaoping Wu, Zixuan Zhang, Jingjing Li, Jiuyu Zong, Lufengzi Yuan, Lingling Shu, Lai Yee Cheong, Xiaowen Huang, Mengxue Jiang, Zhihui Ping, Aimin Xu, Ruby L.C. Hoo

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Modulation of flowering by an alternatively spliced AGL18-1 transcript in Brassica juncea by Qinlin Deng, Huanhuan Lu, Dakun Liu, Yifang Huang, Junjie Feng, Dayong Wei, Zhimin Wang, Qinglin Tang

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