Troxerutin suppresses the stemness of osteosarcoma via the CD155/SRC/β-catenin signaling axis by Junkai Chen, Hongbo Li, Qinglin Jin, Xiaoguang Li, Yiwen Zhang, Jingnan Shen, Gang Huang, Junqiang Yin, Changye Zou, Xinyu Li, Xin He, Xianbiao Xie, Tiao Lin

“…However, despite the passage of three decades, there has been no notable enhancement in the overall survival rate of patients with osteosarcoma. …”
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Artemisinin supplementation in concentrated cottonseed protein basal diets enhances growth, antioxidant capacity, intestinal immunity and microbiota in hybrid grouper (Epinephelus... by Ling Pan, Qi Wang, Weikang Li, Xiaohui Dong, Shiwei Xie, Beiping Tan, Hongyu Liu, Yan Wang

“…Furthermore, it conferred notable advantages related to antioxidant activity, immune modulation, and intestinal health. …”
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Preliminary research indicates that mechanical force through Pioze1 enhances local immunity during NPWT treatment for spinal infections by Hao Xing, Junlin Pan, Huan Liu, Yanan Wang, Zhengqi Chang

“…It is hypothesized that the mechanical force employed in NPWT treatment stimulates the Piezo1 protein, thereby modulating local immune cells and factors, ultimately bolstering local immunity. …”
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Matching-adjusted indirect comparisons of efficacy outcomes between etrasimod and ozanimod for moderately to severely active ulcerative colitis by Vipul Jairath, Tim Raine, Thomas P Leahy, Ravi Potluri, Karolina Wosik, David Gruben, Joseph C Cappelleri, Peter Hur, Lauren Bartolome

“…Aim: Etrasimod and ozanimod are selective sphingosine 1-phosphate receptor modulators targeting the S1P1,4,5, and S1P1,5 receptors, respectively, for the treatment of patients with moderately to severely active ulcerative colitis (UC). …”

CD9 regulates proliferation, invasion, migration and radioresistance of esophageal squamous cell carcinoma by activating AKT/GSK3β signaling pathway by Liubing Hou, Liubing Hou, Zengyao Hao, Ge Zhang, Jiayuan Li, Yu Wang, Xiaoying Xue, Xiaoying Xue, Huandi Zhou, Huandi Zhou, Huandi Zhou

“…Mechanistically, CD9 modulated p-AKT (ser473) and p-Gsk3β (ser9) levels increased to 1.95-fold and 1.42-fold in overexpression models, respectively, with 58% and 33% reductions in knockdown group. …”
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Construction of a circRNA-miRNA-mRNA Regulatory Network for the Immune Regulation of Lung Adenocarcinoma by Hanyi Li, Xin Jin, Wei Li, Fan Ren, Tong Li, Xuanguang Li, Haochuan Yu, Dianxun Fu, Zuoqing Song, Song Xu

“…These circRNAs function through a sponge mechanism, interacting with microRNAs (miRNAs) to modulate mRNA expression levels. Nevertheless, the precise role of the circRNA-miRNA-mRNA regulatory network in immune regulation within lung adenocarcinoma (LUAD) remains inadequately understood. …”
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Recommended coupling to global meteorological fields for long-term tracer simulations with WRF-GHG by D. Ho, M. Gałkowski, M. Gałkowski, F. Reum, S. Botía, J. Marshall, K. U. Totsche, C. Gerbig

“…</p> <p>Here, we analyze transport uncertainties in the commonly used Weather Research and Forecasting (WRF) model coupled with the greenhouse gas module (WRF-GHG), enabling passive tracer transport simulation of <span class="inline-formula">CO₂</span> and <span class="inline-formula">CH₄</span>. …”
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Impact of straight slot impingement jets on heat transfer enhancement of TiO2/H2O nanofluid flow in a square channel: CFD analysis by Anil Kumar, Rajesh Maithani, Sachin Sharma, Ayushman Srivastav, Tabish Alam, Md Irfanul Haque Siddiqui, Dan Dobrotă, Nicolae-Florin Cofaru, Intesaaf Ashraf

“…The $$\:\text{T}\text{i}{\text{O}}_{2}/{\text{H}}_{2}\text{O}$$ nanofluid exhibits a notable enhancement in heat transfer performance compared to pure water. …”
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Multimodal dynamic retinal vessel analysis offers new insights in microvascular defects in Fabry’s disease by Abdelrahman Assaf, Konstantin Kotliar, Arno Schmidt-Trucksäss, Ines Lanzl

“…This was particularly notable in veins at all stages of the vascular reaction and in arteries at all stages except the baseline by more pronounced waves with periods of ~ 50–100 µm. …”
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Gastroprotective Effect of Abelmoschus esculentus (Ex-Maradi Okra Fruit Variety) Against Ethanol-Induced Ulcers in Rats by Muhammad, I., Matazu, K. I., Kankia, I. H., Nasir, A., Yau’, S., Shamsu, S., Suleiman, Z. A., Nasir, R., Sani, A. S., Lawal, R. G., Rawayau, M. A., Darma, I. S., Muhammad, A. N., Bahau’ddeen, S., Fardami, A. Y., Matazu, H. K.

“…Overall, its gastroprotective effects may be possibly mediated by its potential to modulate the antioxidant system and gastric acid levels. …”
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Recent advances in ultra-precision machining of lithium niobate crystals by Yebing TIAN, Chengwei WEI, Xiaomei SONG, Cheng QIAN

“…During fixed abrasive lapping, abrasive embedding is effectively prevented, and surface and subsurface damage are reduced. It also exhibits notable advantages for continuous batch grinding. …”
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Restorative Effects of Synbiotics on Colonic Ultrastructure and Oxidative Stress in Dogs with Chronic Enteropathy by Dipak Kumar Sahoo, Tracey Stewart, Emily M. Lindgreen, Bhakti Patel, Ashish Patel, Jigneshkumar N. Trivedi, Valerie Parker, Adam J. Rudinsky, Jenessa A. Winston, Agnes Bourgois-Mochel, Jonathan P. Mochel, Karin Allenspach, Romy M. Heilmann, Albert E. Jergens

“…To explore potential signaling pathways that might modulate MITO and ER stress, a transcriptomic analysis was also performed. …”
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