When Do Trait‐Based Higher Order Interactions and Individual Variation Promote Robust Species Coexistence? by Gaurav Baruah, György Barabás, Robert John

“…Theoretical studies on HOIs, where a third species modulates pairwise species competition, tend to assign them at random, even though they could be mediated and structured by one‐dimensional traits. …”
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Unveiling the Polypharmacological Potency of FDA-Approved Rebamipide for Alzheimer’s Disease by Israa J. Hakeem, Hadil Alahdal, Hanadi M. Baeissa, Tahani Bakhsh, Misbahuddin Rafeeq, Alaa Hamed Habib, Mohammed Matoog Karami, Maryam A. AL-Ghamdi, Ghadeer Abdullah, Abeer Al Tuwaijri

“…<b>Results:</b> Rebamipide bound effectively to the NR1 ligand-binding core, suggesting modulation of glutamatergic signalling while reducing β-secretase production and regulating neurotransmitter homeostasis through inhibiting monoamine oxidase-A. …”
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Enhancing cognitive abilities through transcutaneous auricular vagus nerve stimulation: Findings from prefrontal functional connectivity analysis and virtual brain simulation by Sora An, Se Jin Oh, Shinhee Noh, Sang Beom Jun, Jee Eun Sung

“…Moreover, the changes in performance due to taVNS, which varied based on baseline performance, exhibited a notable alignment with the FC changes in the mPFC. …”
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Comparative analysis of gut microbiota in healthy and diarrheic foals by Di Zhu, Siyu Li, Zhixiang Xu, Md. F. Kulyar, Xu Bai, Yu Wang, Boya Wang, Emaan Khateeb, Dandan Deng, Lidan Wang, Yuji Chen, Aizhen Guo, Yaoqin Shen

“…The results unveiled significant reductions in gut bacterial and fungal diversities among foals experiencing diarrhea, accompanied by notable shifts in the composition of gut microbial communities. …”
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The role of MAPK pathway in gastric cancer: unveiling molecular crosstalk and therapeutic prospects by Weiwei Yuan, Yin Shi, Shiping Dai, Mao Deng, Kai Zhu, Yuanmin Xu, Zhangming Chen, Zhou Xu, Tianlong Zhang, Song Liang

“…Abstract Gastric cancer remains a significant health burden globally, especially prevalent in Asian and European regions. Despite a notable decline in incidence in the United States and Western Europe over recent decades, the disease’s persistence underscores the urgency for advanced research in its pathogenesis and treatment strategies. …”
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Altered connection properties of the left dorsolateral superior frontal gyrus in de novo drug-naïve insomnia disorder by Hui Wang, Xianjun Ma, Xingru Xu, Qian Ning, Benyu Qiao, Bofeng Yang, Na Sun, Dong Xu, Xin Tang

“…The results indicate that altered DC properties of the left dorsolateral SFG might serve as a diagnostic marker for ID and a potential therapeutic target for brain function modulation.…”
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Structural characteristics of Brassica rapa L. Polysaccharide and its bioactivity on alcoholic liver injury by Xin Xu, Xinxin Yang, Meng Wang, Jingrong Zhu, Jing Li, Caiyue Chen, Jiameng Liu, Jiahuan Zheng, Bei Fan, Fengzhong Wang, Jing Sun

“…Strong antioxidant activity was displayed by BRLPP, which showed notable scavenging effects on DPPH and ABTS+ radicals. …”
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The janus face of astrocytes in multiple sclerosis: Balancing protection and pathology by Ahmad A. Abulaban, Hayder M. Al-kuraishy, Ali I. Al-Gareeb, Ali K. Albuhadily, Mustafa M. Shokr, Athanasios Alexiou, Marios Papadakis, Gaber El-Saber Batiha

“…Emerging therapies like dimethyl fumarate (DMF) and fingolimod modulate astrocyte reactivity, targeting oxidative stress and sphingosine-1-phosphate receptors to mitigate neuroinflammation. …”
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Adipose-derived exosomes ameliorate skeletal muscle atrophy via miR-146a-5p/IGF-1R signaling by Mengran Qin, Jiahao Zhu, Lipeng Xing, Yaotian Fan, Junyi Luo, Jiajie Sun, Ting Chen, Yongliang Zhang, Qianyun Xi

“…It can be transported through the pathway of exosomes derived from adipose tissue, ultimately ameliorating skeletal muscle atrophy and modulating body mass index (BMI). Graphical abstract…”
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Zinc toxicity induces intestinal cell death via inhibiting NAD+ synthesis in mice and IPEC-J2 cells by Lingjun Chen, Feifei Huang, Leilei Zhu, Xin Tian, Mohan Zhou, Jie Feng

“…This indicates that the modulation of NAD+ synthesis may prove an effective strategy for the minimization or elimination of Zn toxicity. …”
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Tactile imagery affects cortical responses to vibrotactile stimulation of the fingertip by Marina Morozova, Lev Yakovlev, Nikolay Syrov, Mikhail Lebedev, Alexander Kaplan

“…TI caused event-related desynchronization (ERD) of the contralateral μ-rhythm, with a notable correlation between ERD during imagery and real stimulation across subjects. …”
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Eagle-YOLOv8: UAV Object Detection Inspired by the Eagle-Eye Vision System by Dianwei Wang, Zehao Gao, Jie Fang, Yuanqing Li, Zhijie Xu

“…First, inspired by the double fovea mechanism of the eagle eye, we construct a long-focus attention module, which can promote the network to focus on the target and pay more attention to discriminative features. …”
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Omega-3 Fatty Acids and Exercise in Obesity Management: Independent and Synergistic Benefits in Metabolism and Knowledge Gaps by Viviana Sandoval, Álvaro Vergara-Nieto, Amanda Bentes, Saulo Silva, Carolina Núñez, Sergio Martínez-Huenchullán

“…Specifically, MICT improves body fat distribution and mitochondrial efficiency, whereas HIIT has notable effects on metabolic adaptability and insulin signaling. …”
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Lacticaseibacillus paracasei sh2020 induced antitumor immunity and synergized with anti-programmed cell death 1 to reduce tumor burden in mice by Shi-Long Zhang, Bing Han, Yu-Qin Mao, Zheng-Yan Zhang, Zhan-Ming Li, Chao-Yue Kong, You Wu, Guo-Qiang Chen, Li-Shun Wang

“…L. paracasei sh2020 showed the most notable anti-tumor immunity in the mice with gut dysbiosis. …”
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Post-operative supplementation with vitamin D after mucogingival surgery significantly enhances autophagy and improves life quality following feline chronic gingivostomatitis by Yung-Kai Huang, Chung-Wei Chen, Ting-Yi Renn, Ming-Yi Shen, Igor V. Klimenkov, Nikolay P. Sudakov, Sandeep Kumar Singh, Hung-Ming Chang

“…Moreover, both types of vitamin D considerably enhanced the expression of VDR and light chain 3B (LC3B, a biochemical marker for autophagy) within the affected tissues, with the most notable change observed in cats that received fat-soluble vitamin D. …”
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Diverse mechanisms of metaeffector activity in an intracellular bacterial pathogen, Legionella pneumophila by Malene L Urbanus, Andrew T Quaile, Peter J Stogios, Mariya Morar, Chitong Rao, Rosa Di Leo, Elena Evdokimova, Mandy Lam, Christina Oatway, Marianne E Cuff, Jerzy Osipiuk, Karolina Michalska, Boguslaw P Nocek, Mikko Taipale, Alexei Savchenko, Alexander W Ensminger

“…Metaeffectors, along with other, indirect, forms of effector–effector modulation, may be a common feature of many intracellular pathogens—with unrealized potential to inform our understanding of how pathogens regulate their interactions with the host cell.…”
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Non-Bovine Milk as Functional Foods with Focus on Their Antioxidant and Anti-Inflammatory Bioactivities by Yan Li, Qingshan Ma, Mengmeng Li, Wenqiang Liu, Yihong Liu, Menghan Wang, Changfa Wang, Muhammad Zahoor Khan

“…Camel and donkey milk demonstrate notable antioxidant and anti-inflammatory properties that may exceed those of conventional milk sources. …”
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Infiltration of innate and adoptive lymphoid cells in 4T1 and MC4-L2 breast cancer models by Reihane Rasooli Tehrani, Hossein Asgarian-Omran, Saeid Taghiloo, Reza Valadan, Soheil Azizi, Abolghasem Ajami

“…Results: Both tumor models showed a notable increase in T-cell frequency at the early stage of tumor growth. …”
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Remote sensing-based assessment of four decades of land use/land cover change in the Sigi River Watershed, East Usambara Mountains, Tanzania by Simon Chidodo, Simon Chidodo, Lulu Zhang, Azin Zarei, Karl-Heinz Feger

“…Slope steepness further modulated LULC dynamics, with steeper slopes across all elevations showing notable forest loss, while gentler slopes may have undergone earlier land conversion, preceding the study period.Discussion:The study underscores the importance of integrating topographic attributes into LULC assessments to better understand landscape transformation processes and support sustainable land-use planning and watershed management.…”
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Landscape of mobile genetic elements and their functional cargo across the gastrointestinal tract microbiomes in ruminants by Yijun Tang, Pengchao Zhan, Yingjian Wu, Tao Zhang, Di Yin, Yunlong Gao, Yueying Yu, Shengnan Qiu, Jiaqi Zhao, Xue Zhang, Zhe Ma, Yanting Chen, Liang Zhao, Shengyong Mao, Jinhu Huang, Wei-Hua Chen, Jinxin Liu

“…The findings provide a valuable resource for advancing research on microbial functionality and offer insights with potential applications for enhancing ruminant health and productivity, through strategies aimed at modulating the microbiome in agricultural contexts. …”
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