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    The Synthetic Cannabinoids ADB-FUBINACA Modulate Mitochondrial Function and Dynamics at Biologically Relevant Concentrations During In Vitro Neurodifferentiation by R.F. Malheiro, H. Carmo, F. Carvalho, J.P. Silva

    Published 2024-12-01
    “…Different mechanisms seem to underlie mitochondrial function-related effects, as only the modulation of energy supply was dependent on CB1R activation. …”
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    Natural ligand 3,3’-diindolylmethane functions as an AHR agonist to modulate angiogenesis and organ development in chicken embryos by Gee-yea Lim, Hao Chen, Woo-seon Song, Dong-hee Koh, Dong-ha Kim, Hisato Iwata, Eun-Young Kim

    Published 2025-09-01
    “…Recent studies have highlighted that interactions between AHR and certain natural ligands can modulate inflammation and immune responses, offering therapeutic potential for a wide range of diseases. …”
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    Low-frequency rTMS modulates small-world network properties in an AVH-related brain network in schizophrenia by Lin Zhang, Li Guo, Xiaohui Liu, Jing Han, Yuanqiang Zhu, Chaozong Ma, Ye Li, Weiliang Ye

    Published 2025-04-01
    “…Functional connectivity analyses revealed significant reductions in hyperconnectivity between the right middle temporal gyrus (MTG) and superior putamen, as well as between the left TPJ and left lateral prefrontal cortex (LPFC). Notably, responders showed greater connectivity changes, which were correlated with AVH severity reduction, highlighting the role of network modulation in treatment response.ConclusionThese findings support the network dysregulation model of AVH in schizophrenia and demonstrate that rTMS can modulate AVH-related connectivity, partially restoring network efficiency. …”
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    Evolving Dynamics of Fermented Food Microbiota and the Gut Microenvironment: Strategic Pathways to Enhance Human Health by Antonia Terpou, Divakar Dahiya, Poonam Singh Nigam

    Published 2025-07-01
    “…These metabolites contribute to improved gut barrier function, modulation of immune responses, and overall metabolic health. …”
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    Lactiplantibacillus plantarum dfa1 reduces obesity caused by a high carbohydrate diet by modulating inflammation and gut microbiota by Thunnicha Ondee, Krit Pongpirul, Lampet Wongsaroj, Sayamon Senaprom, Suphot Wattanaphansak, Asada Leelahavanichkul

    Published 2025-07-01
    “…Microbiome analysis revealed diet-induced dysbiosis, with a notable difference between HGD and HBD impacts, particularly in the Fermicutes/Bacteroides ratio and Akkermansia spp. abundance, which was significantly elevated in the HBD + Lp group. …”
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    Aqueous extract of Solanum americanum Mill. relieves functional constipation by modulating the enteric nervous system and gut micro-ecosystems by Xiaoyu Gao, Xiaoyu Gao, Xiaoyu Gao, Yanan Li, Yifan Hu, Yifan Hu, Weixing Yang, Lei Peng, Jun Sheng, Yang Tian, Lu Yao, Yan Zhao

    Published 2025-05-01
    “…This finding suggests that SAAE may alleviate FC by modulating the enteric nervous system. Notably, SAAE alleviated loperamide-induced gut inflammation, damaged gut barrier, and gut microbiota disruption. …”
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    Genetically-stable engineered optogenetic gene switches modulate spatial cell morphogenesis in two- and three-dimensional tissue cultures by Hannes M. Beyer, Sant Kumar, Marius Nieke, Carroll M. C. Diehl, Kun Tang, Sara Shumka, Cha San Koh, Christian Fleck, Jamie A. Davies, Mustafa Khammash, Matias D. Zurbriggen

    Published 2024-12-01
    “…These advancements demonstrate the capability of precise spatiotemporal modulation in tissue engineering and open up new avenues for developing programmable 3D tissue and organ models, with significant implications for biomedical research and therapeutic applications.…”
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    Strategic energy-level modulation in porous heterojunctions: advancing gas sensing through Type-I to Type-II transitions by Yong-Jun Chen, Yi-Ming Xu, Xiao-Liang Ye, Zhi-Peng Luo, Shi-Peng Zhu, Ke-Feng Li, Jiang-Feng Lu, Guan-E Wang, Gang Xu

    Published 2025-07-01
    “…Abstract To significantly enhance reaction efficiency of porous heterojunctions in various applications, precise engineering of customization heterostructures through energy-level modulation is indispensable. Herein, the preparation of a core-shell porous heterojunction, UiO-66@TDCOF, is reported. …”
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    The TaNHLP1-TaRACK1A module regulates tillering via abscisic acid signaling in wheat by Yaoqi Si, Shuiquan Tian, Jianqing Niu, Qiao Lu, Qiushuang Shang, Shengwei Ma, Zhimeng Zhang, Tingting Du, Huilan Wu, Jundong Li, Xiansheng Zhang, Fang Wang, Hong-Qing Ling, Shusong Zheng

    Published 2025-08-01
    “…Importantly, both the TaNHLP1 and TaRACK1A mutations promote ABA accumulation in the shoot bases and tiller buds. Notably, the NHLP1-RACK1 module is conserved across monocots and eudicots, and natural variations in the promoter of TaNHLP1-A enhance its transcriptional activity, leading to increased tiller number and yield. …”
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