Functional changes in the hypothalamic-pituitary-adrenal axis after successful cardiopulmonary resuscitation by Le An, Zhijiang Qi, Huan Shao, Chunsheng Li

“…Cardiac arrest (CA) is a terminal event that results in a range of pathophysiological changes in the body, most notably, systemic ischemia-reperfusion injury. The hypothalamic-pituitary-adrenal (HPA) axis is an important neuroendocrine system that modulates adrenocortical hormone release. …”
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Identification of the key material degradation mechanisms affecting silicon solar cells: Systematic literature review by Eshetu Tadesse Ymer, Hirpa Gelgele Lemu, Mesay Alemu Tolcha

“…Environmental elements are identified as major contributors to power output degradation, with observed annual losses ranging from 1.8% to 2% in hot-humid regions, notably higher than the approximately 0.3% reported in temperate zones. …”
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Proteomic study of evolved Pseudomonas aeruginosa strains grown in Staphylococcus aureus- and Klebsiella pneumoniae-conditioned media by Yanrong Pan, Tin Yan Wong, Jordy Evan Sulaiman, Henry Lam

“…These suggest the potential role of SA and KP in modulating the regulation of T6SS HSIs in PA.…”
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Seed priming with salicylic acid enhances salt stress tolerance by boosting antioxidant defense in Phaseolus vulgaris genotypes by Mohammad Reza Karimi, Manijeh Sabokdast, Hamid Korang Beheshti, Ali Reza Abbasi, Mohammad Reza Bihamta

“…The novelty of this work lies in the detailed elucidation of SA's role in modulating antioxidant defenses and ion homeostasis in different genotypes, providing new insights into breeding programs and agricultural practices aimed at improving crop resilience and productivity in increasingly saline environments.…”
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N6‐Methyladenosine modification mediated by METTL3 promotes DNA‐PKcs expression to induce anlotinib resistance in osteosarcoma by Yining Zhang, Guohong Shen, Dan Zhang, Tingting Meng, Zhaorui Lv, Lei Chen, Jianmin Li, Ka Li

“…DNA‐PKcs affects anlotinib‐induced autophagy by interacting with Beclin‐1 and regulating its ubiquitination. Notably, PRKDC mRNA, encoding DNA‐PKcs, underwent N6‐Methyladenosine (m6A) modification. …”
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Exploring lipidome mediated inflammatory pathways in acute pancreatitis using mendelian randomization by Wenbin Liu, Song Yang, Yuhan Li, Dava Tenzing, Ruizi Shi, Yang Jiang, Hao Deng, Enqiang Mao, Ying Chen, Yihui Wang

“…Further analysis elucidated the intricate interplay between specific lipid species and inflammatory mediators in influencing AP incidence. Notably, Sterol ester (27:1/20:4) and several phosphatidylcholine species, including PC (17:0_20:4), PC (18:0_20:4), PC (18:0_20:5), and PC (O-18:2_20:4), were negatively associated with AP risk. …”
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Effects of Cyclic Adenosine Monophosphate Nanoliposomes on Growth Performance, Gut Development and Microbiota of Broilers by Li Chen, Li Wang, Sheng Huang, Guoqi Su, Shan Jiang, Feiyun Yang, Jingxiu Huang

“…In conclusion, dietary addition of Nano-cAMP promotes jejunal development, modulates appetite hormones mRNA expression, enhances absorption capacity, increases the relative abundance of intestinal probiotics such as <i>Bifidobacterium</i> and cellulose-degrading bacteria such as <i>Ruminococcus torques group</i>, optimizes gut microbiota composition, and ultimately reduces the feed-to-gain ratio in broilers.…”
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MIND diet score and its association with metabolic dysfunction-associated steatotic liver disease and gut microbiota profiles: a cross-sectional study by Shengbo Yang, Litao Zhang, Mingli Hu, Weina He

“…Each 1-unit increase in MIND diet score was significantly associated with reductions in fasting insulin (β = −0.20 μU/mL; p &lt; 0.001), HOMA-IR (β = −2.11; p &lt; 0.001), CRP (β = −2.12; p &lt; 0.001), LPS (β = −8.52; p &lt; 0.001). Notably, Simpson diversity index scores were higher, and the Firmicutes-to-Bacteroidetes ratio (F/B ratio) was lower, among participants with greater MIND adherence, reflecting improved microbial balance. …”
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Ahiflower seed and its press cake as sources of nutrients for laying hens and omega-3 fatty acids in their eggs by Roseline O. Ogory, Greg Cumberford, Deborah Adewole

“…The n-6/n-3 ratio was reduced (P<0.001) by 10 %FS and 10 %AS compared to APC and CD. Dietary treatments modulated fecal microbiota differently, but notably, Lactobacillus was more abundant when hens were fed 5 %AS compared to other treatments. …”
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Strawberry dietary intervention influences diversity and increases abundances of SCFA-producing bacteria in healthy elderly people by Franziska Meiners, Bernd Kreikemeyer, Patrick Newels, Ingmar Zude, Michael Walter, Alexander Hartmann, Daniel Palmer, Georg Fuellen, Israel Barrantes

“…Notably, the group consuming the highest amount of strawberries (without capers in olive oil) initially had higher abundances of potentially pathogenic bacteria. …”
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Human platelet lysate enhances small lipid droplet accumulation of human MSCs through MAPK phosphorylation by Ping Du, Xuelian Tao, Javad Harati, Yue Shi, Liang Xiao, Xian Li, Haobo Pan, Peng-Yuan Wang

“…Notably, the lipid droplets in hPL-treated MSCs were significantly smaller than those in adipocyte-like cells differentiated from MSCs, highlighting hPL’s distinctive role in lipid production. …”
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Transcription factors containing both C2H2 and homeobox domains play different roles in Verticillium dahliae by Chen Tang, Haifeng Wang, Xianjiang Jin, Wenwen Li, Yonglin Wang

“…Our results indicate that VdChtf3 is a potential specific regulator of microsclerotial formation, modulating the expression of pectinase-encoding genes. …”
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Assessing the Skeletal Muscle Pump During Lower Limb Counterpressure: Lags and Causality in Cardiovascular Regulation by Silvin P. Knight, Eoin Duggan, Feng Xue, Roman Romero‐Ortuno

“…Conclusions These findings underscore the role of the skeletal muscle pump in modulating venous return and cardiac output during PCMs. …”
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Effects of Sodium Acetate and Sodium Butyrate on the Volatile Compounds in Mare’s Milk Based on GC-IMS Analysis by Shengchen Zheng, Jianwei Lin, Yong Chen, Changjiang Zang, Fan Yang, Jiahao Li, Xiaobin Li

“…In conclusion, sodium acetate and sodium butyrate enhance milk flavor by modulating milk composition and metabolic parameters, providing a scientific foundation for improving the quality of mare milk products.…”
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CD27 on IgD-CD38-B Cells Mediates the Coprococcus-COPD Link by Gao Y, Chen L, Zhang J, Wen Z

“…Additionally, 15 immune cell traits displayed significant associations with Coprococcus. Notably, CD27 expressed on IgD− CD38− B cells emerged as a potential contributor to COPD development (OR = 1.04, 95% CI: 1.00– 1.07, P = 0.03). …”
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Investigation of the Anti-Lung Cancer Mechanisms of <i>Taraxacum officinale</i> Based on Network Pharmacology and Multidimensional Experimental Validation by Jianing Liu, Hailing Yang, Ran Liu, Dongjin Sun, Yongbao Liu, Jing Lu, Jinbiao Liu, Junrui Lu

“…The PPI network highlighted 16 core targets, notably TP53, CASP3 and EGFR. Functional enrichment analysis suggested that dandelion might exert its anticancer effects by modulating the tumor microenvironment through the regulation of these critical targets. …”
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Resveratrol improved atherosclerosis by increasing LDLR levels via the EGFR-ERK1/2 signaling pathway by Dandan Hu, Litian Wang, Lin Qi, Xiangxuan Yang, Yamin Jin, Huailiu Yin, Yewei Huang, Jun Sheng, Xuanjun Wang

“…It indicated that RSV modulated LDLR gene expression by activating EGFR-ERK1/2 pathway. …”
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Reevaluation of the gastrointestinal methanogenic archaeome in multiple sclerosis and its association with treatment by Pei Yee Woh, Yehao Chen, Christina Kumpitsch, Rokhsareh Mohammadzadeh, Laura Schmidt, Christine Moissl-Eichinger

“…However, treated MS patients exhibited higher abundances of Methanobrevibacter smithii and M. sp900766745 compared to untreated patients. Notably, M. sp900766745 abundance correlated with lower disease severity scores in treated patients. …”
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Platelet-derived HMGB1 induces NETosis, exacerbating brain damage in the photothrombotic stroke model by Sang-A. Oh, Song-I. Seol, Dashdulam Davaanyam, Seung-Woo Kim, Ja-Kyeong Lee

“…Therefore, targeting NETosis through modulation of HMGB1 presents a promising multipotent therapeutic strategy for mitigating ischemic brain damage.…”
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Investigation into the influence of mild hypothermia on regulating ferroptosis through the P53-SLC7A11/GPX4 signaling pathway in sepsis-induced acute lung injury by Liujun Tao, Jie Xu, Liangyan Jiang, Juntao Hu, Zhanhong Tang

“…Conclusion Mild hypothermia attenuates S-ALI and modulates ferroptosis through the P53-SLC7A11/GPX4 signaling pathway.…”
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