SGTCDA: Prediction of circRNA-drug sensitivity associations with interpretable graph transformers and effective assessment by Hongwei Xia, Caiyue Dong, Xinxing Chen, Zhuoyu Wei, Lichuan Gu, Xiaolei Zhu

“…Due to the high cost of biomedical experiments for detecting the associations between circRNAs and drug sensitivities, several computational methods have been developed. …”
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An NLP-Based Framework to Spot Extremist Networks in Social Media by Andrés Zapata Rozo, Daniel Díaz-López, Javier Pastor-Galindo, Félix Gómez Mármol, Umit Karabiyik

“…Knowledge graphs achieved in our use case allow us to identify how nodes that promote HSM are interconnected and work collaboratively. …”
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Case Report: A very rare case of diffuse large B-cell lymphoma with cardiac and ovarian involvement by Yadan Du, Yadan Du, Yuting Tian, Yawen Chen, Shuaihua Cheng, Jianping Gao

“…BackgroundDiffuse large B-cell lymphoma (DLBCL) is the most prevalent type of aggressive lymphoma, commonly spreading to sites such as the lymph nodes, spleen, bone marrow, liver, lungs, and central nervous system. …”
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Molecular Basis of Acute Cystitis Reveals Susceptibility Genes and Immunotherapeutic Targets. by Ines Ambite, Manoj Puthia, Karoly Nagy, Caterina Cafaro, Aftab Nadeem, Daniel S C Butler, Gustav Rydström, Nina A Filenko, Björn Wullt, Thomas Miethke, Catharina Svanborg

“…Yet, it is possible to distinguish protective from destructive effects of innate immune activation and selectively attenuate molecular nodes that create pathology. Here, we identify acute cystitis as an Interleukin-1 beta (IL-1β)-driven, hyper-inflammatory condition of the infected urinary bladder and IL-1 receptor blockade as a novel therapeutic strategy. …”
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Future research of supply chain resilience: Network perspectives and incorporation of more stakeholders by L. Jeff Hong, Jinzhi Li, Xiaole Wu, Shuyue Yi

“…From the network perspective, we review the literature on vulnerable nodes & links identification, risk propagation modeling, network resilience measures, and disruption mitigation strategies. …”
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Key role of the GITR/GITRLigand pathway in the development of murine autoimmune diabetes: a potential therapeutic target. by Sylvaine You, Lynn Poulton, Steve Cobbold, Chih-Pin Liu, Michael Rosenzweig, Douglas Ringler, Wen-Hui Lee, Berta Segovia, Jean-François Bach, Herman Waldmann, Lucienne Chatenoud

“…Constitutive high expression of GITR is detected only on Tregs. GITR interacts with its ligand mainly expressed on antigen presenting cells and endothelial cells. …”
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Depletion of regulatory T cells enhances the T cell response induced by the neoantigen vaccine with weak immunogenicity by Ruichen Huang, Qiao Zhou, Jiajun Liu, Yang Xia, Yang Jiao, Bi Zhao, Tangtao Feng, Haosu Zhou, Xiuyan Song, Hao Qin, Jun Wang, Lan Cheng, Yunye Ning, Qinying Sun, Yanfang Liu, Xiaoping Su, Yuchao Dong, Wei Zhang

“…However, numerous neoantigens show poor immunogenicity, and the immune inhibitory factors of present in both tumors and tumor-draining lymph nodes impair the efficacy of cancer neoantigen vaccine. …”
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Age-related characteristics in differentiated thyroid cancer: a 20-year single-center retrospective analysis in pediatric and adolescent patients by Laura Leite-Almeida, Rita Santos Silva, Margarida Vicente-Ferreira, Carla Costa, Norberto Estevinho, Cíntia Castro-Correia, Sofia Ferreira, Maria Bom-Sucesso

“…Younger patients demonstrated more aggressive tumor characteristics and higher recurrence rates, underscoring the need for age-specific management strategies. Early detection, comprehensive surgical intervention, and multidisciplinary follow-up are essential for achieving optimal outcomes.…”
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Uncovering Surgical Dynamics and Trends in Early Breast Cancer Stage at Diagnosis: Key Insights From a Two-Decade Argentine Database Analysis by Pablo Mandó, Verónica Fabiano, Soledad Gomez Guasch, Giuliana Colucci, Rodrigo Sánchez-Bayona, Federico Coló, Martín Loza, Francisco Von Stecher, Mora Amat, Máximo de la Vega, Maria Victoria Costanzo, Adrian Nervo, Jorge Nadal, Reinaldo Chacón, Florencia Perazzo

“…Significant differences were observed in the axillary procedure performed, with sentinel lymph node biopsy increasing from 14.9% (2000-2004) to 69.5% (2015-2019; P < .001). …”
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Causal knowledge graph construction for enterprise innovation events in the digital economy and its application to strategic decision-making by Pengfei Wu, Bingtao Xu, Xuhan Zhang

“…The goal is to represent events (e.g. product launches, strategic investments) as nodes and their causal relationships as directed edges, enabling advanced reasoning about how one innovation leads to another. …”
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Health Monitoring of Carbon Fiber Reinforced Building Materials Based on Phase Unwrapping Algorithm by Min Yan, Jianjun Zhou, Shuai Guo, Yanlong Li

“…Engineers cannot monitor real-time data related to the status of building materials, such as whether the structure is complete, whether nodes are effective, and specific displacement situations. …”
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Self-assembling TLR2 agonists promote mucosal immune responses without pulmonary immunopathologic injuries in mice by Zhangping Huang, Caiguanxi Deng, Lin Peng, Liru Shang, Juan Jiang, Wei Yu, Hao Yang, Jing Liu, Liwei Jiang, Teng Zuo, Ji Wang, Xiafeng Wang

“…These findings highlight the potential of self-assembled Diprovocim as a safe and effective adjuvant for mucosal vaccines, offering a promising strategy for combating respiratory infections.…”
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Feasibility of Multiplex Cytokine Profiling in Preterm Labor: Towards Biomarker Discovery by Ruth Llano, Inés Ardao, José Manuel Brea, Luz Romero, María P. Pata, Antón L. Martínez, Manuel Macía, María Isabel Loza

“…In this study, we describe a novel non-invasive approach based on the multiplex detection of inflammatory cytokines in small urine volumes from pregnant women. …”
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Digital Academic Leadership in Higher Education Institutions: A Bibliometric Review Based on CiteSpace by Olaniyi Joshua Olabiyi, Carl Jansen van Vuuren, Marieta Du Plessis, Yujie Xue, Chang Zhu

“…This was the result of a multi-step refinement process using CiteSpace’s default thresholds and clustering algorithms to detect the most influential nodes based on centrality, citation burst, and network clustering. …”
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Research on path planning for coal mine rescue robots by ZHU Hongbo, YIN Hongliang

“…Additionally, a dynamic weighting factor is added to the estimated cost function to eliminate irrelevant expanded nodes during pathfinding, thus improving search efficiency. …”
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From Viewing to Structure: A Computational Framework for Modeling and Visualizing Visual Exploration by Kuan-Chen Chen, Chang-Franw Lee, Teng-Wen Chang, Cheng-Gang Wang, Jia-Rong Li

“…An adaptive buffer zone method is further employed to quantify the strength of connections between regions and to delineate potential visual nodes and transition pathways. Three design-trained participants were invited to observe the same painting while performing a think-aloud task, with one participant selected for the detailed demonstration of the analytical process. …”
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A survey of data-driven fault-diagnosis methods for large-scale industrial production processes by Qianxiang YU, Qing LI, Linlin LI, Yixuan WANG

“…Meanwhile, consensus analysis focuses on the communication topology of the nodes, ensuring that all nodes converge to a unified data state at any instant. …”
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Network analysis of chronic disease among middle-aged and older adults in China: a nationwide survey by Chen Chen, Chen Chen, Hongfeng Wu, Likun Yang, Ke Kan, Xinping Zhang, Su Zhang, Rufu Jia, Xian Li

“…Community detection identified groups of closely related diseases using the Louvain algorithm. …”
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The role of 5G network in revolutionizing agriculture for sustainable development: A comprehensive review by Wasif ur Rehman, Mohsin Ali Koondhar, Samandar Khan Afridi, Lutfi Albasha, Idris H. Smaili, Ezzeddine Touti, Mouloud Aoudia, Wassim Zahrouni, Ibrahim Mahariq, M.M.R. Ahmed

“…Additionally, the paper explores development optimization of various nodes, fault detection, self-healing mechanisms, AI application optimization, and security issues specific to 5G-enabled smart agriculture. …”
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Multiple liver metastases with synchronous gastric and transverse colon cancer diagnosed by gastric perforation successfully treated by SOX plus bevacizumab and completely resected... by Ryu Matsumoto, Shinichiro Mori, Yoshiaki Kita, Hiroko Toda, Ken Sasaki, Takaaki Arigami, Daisuke Matsushita, Hiroshi Kurahara, Kosei Maemura, Shoji Natsugoe

“…The [18F]-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) showed 18F-FDG uptake by the colon tumor and multiple liver metastases, but there was no uptake in the gastric tumor or lymph nodes. We retrospectively reevaluated the CT findings from a local hospital and detected a liver nodule in segment 2/3 (from 35 to 60 mm) and segment 6 (from 26 to 57 mm), and the tumors had dramatically grown in size in only 2 months. …”
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