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  1. 1841

    Harnessing AlphaFold to reveal hERG channel conformational state secrets by Khoa Ngo, Pei-Chi Yang, Vladimir Yarov-Yarovoy, Colleen E Clancy, Igor Vorobyov

    Published 2025-07-01
    “…Remarkably, AlphaFold not only predicts inactivation mechanisms of the hERG channel that prevent ion conduction but also uncovers novel molecular features explaining enhanced drug binding observed during inactivation, offering a deeper understanding of hERG channel function and pharmacology. …”
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    Article
  2. 1842

    MMPW-Net: Detection of Tiny Objects in Aerial Imagery Using Mixed Minimum Point-Wasserstein Distance by Nan Su, Zilong Zhao, Yiming Yan, Jinpeng Wang, Wanxuan Lu, Hongbo Cui, Yunfei Qu, Shou Feng, Chunhui Zhao

    Published 2024-11-01
    “…Firstly, we introduce a light backbone-heavy neck architecture, named the Global Context Self-Attention and Dense Nested Connection Feature Extraction Network (GC-DN Network), which efficiently extracts and fuses multi-scale features of the target. …”
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    Article
  3. 1843

    Genome-wide analysis of m6A-modified circRNAs in the mouse model of myocardial injury induced by obstructive sleep apnea by Jiuhuang Lan, Yuhui Wang, Chang Liu, Hongli Chen, Qingshi Chen

    Published 2025-04-01
    “…GO analyses and KEGG analyses were conducted to predict the potential functions of these m6A-modified circRNAs. …”
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    Article
  4. 1844

    Meanings of family under the perspective of parents of adolescent students by Francisca Georgina Macedo de Sousa, Leda Barros de Castro, Ana Larissa Araujo Nogueria, Italo Rodolfo Silva, Dennyse Cristina Macedo da Silva, Nayra Michele Anjos Amorim

    Published 2014-06-01
    “…Eight themes emerged: Structure, values and meanings of family; Roles and functions of family members; Family and school; Family dynamics and the health-disease process in the family; Affective bonds and family relationships; Strategies for family functioning; Feelings and support network; Adolescence and the adolescent in the family. …”
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    Article
  5. 1845

    Placental Vimentin Expression in Preeclampsia and Gestational Diabetes Mellitus by Fırat Asir, Suleyman Cemil Oglak, Tugcan Korak, Fatih Tas, Mehmet Yilmaz, Fikri Erdemci, Firat Sahin, Hayat Ayaz, Emine Zeynep Yilmaz, Gokhan Bolluk

    Published 2024-04-01
    “…A semiquantitative measurement was done between groups by comparing the Vimentin signal and significance was calculated. Network construction and pathway enrichment analysis were conducted using Cytoscape (v3.10.1) and ShinyGO, respectively. …”
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    Article
  6. 1846

    eHealth interventions for chronic pain: Protocol for a systematic review and meta-analysis by Rosario Caruso, Pier Mario Perrone, Karen Barros Parron Fernandes, Cristina Arrigoni, Arianna Magon, Gianluca Conte, Silvia Belloni, Silvana Castaldi

    Published 2025-12-01
    “…A network meta-analysis (NMA) will be conducted to compare different eHealth modalities and identify which features contribute most to positive outcomes. …”
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    Article
  7. 1847
  8. 1848
  9. 1849

    Machine-learning based optimizing the neutronic and thermal-hydraulic performance in a VVER-1000 mixed-core as well as fuel burnup assessment by A. Koraniany, G.R. Ansarifar

    Published 2025-06-01
    “…The reactor core of a functioning power plant usually contains hundreds of fuel assemblies. …”
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    Article
  10. 1850

    Identification of Exposed Submarine Cable Status based on Optimized VMD-GAF-MCNN for Multi Sensor Fusion by WANG Wei, WANG Wendong, YOU Peng, XIAO Zexin, AN Bowen, CUI Guiyan

    Published 2025-06-01
    “…The training set is used to train the network, while the test set verifies the network's effectiveness in identifying the exposed state of the submarine cable.…”
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    Article
  11. 1851

    Building electrical consumption patterns forecasting based on a novel hybrid deep learning model by Nasser Shahsavari-Pour, Azim Heydari, Farshid Keynia, Afef Fekih, Aylar Shahsavari-Pour

    Published 2025-06-01
    “…A comparative analysis was conducted against benchmark models, including the generalized regression neural network (GRNN) and adaptive neuro-fuzzy inference system (ANFIS), to validate the efficacy of the proposed approach. …”
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    Article
  12. 1852

    The Silk Road as a Skilled Practice: taking the two tea roads as cases by CHEN Wei

    Published 2025-06-01
    “…The Silk Road, an ancient network of trade and cultural exchange, has been a subject of significant scholarly interest, particularly in China, Russia, and Mongolia. …”
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  13. 1853

    Novel insights into the molecular mechanisms of sepsis-associated acute kidney injury: an integrative study of GBP2, PSMB8, PSMB9 genes and immune microenvironment characteristics by Haiting Ye, Xiang Zhang, Pengyan Li, Mei Wang, Ruolan Liu, Dingping Yang

    Published 2025-03-01
    “…We used differentially expressed genes (DEGs) and weighted gene co-expression network analysis (WGCNA) to identify characteristic genes associated with SA-AKI and conducted enrichment analyses. …”
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    Article
  14. 1854

    Identification of unique biomarkers for proliferative diabetic retinopathy with tractional retinal detachment by proteomics profiling of vitreous humor by Yuyan Liu, Rongjie Wei, Yong Tang, Shuo Sun, Wei Zhang, Yu Zhou, Zhenhua Pan, Quanhong Han, Xiujuan Zhao, Yanhua Chu

    Published 2025-04-01
    “…By employing bioinformatics tools for GO and KEGG pathway annotation, as well as conducting protein-protein interaction(PPI) network analysis, we investigated the functional enrichment of proteins in the TRD vitreous and their associated pathways. …”
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  15. 1855

    Freely Selective Analog and Digital Resistive Switching Behavior of In2Se3 Devices for Storage and Neuromorphic Applications by Siying Tian, Changhao Wang, Yuanjie Wang, Honghao Wang, Chenxi Gao, Weisen Hu, Jia Wei, Fengling Chen, Dapeng Sun, Xu Zheng, Chaobo Li, Chujun Yin

    Published 2025-06-01
    “…Reconfigurable logic functions and an artificial neural network (ANN) with outline learning accuracy (≈89%) for handwritten digit recognition are achieved. …”
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  16. 1856

    Acupuncture treatment of vascular cognitive impairment through peripheral nerve stimulation pathway: a scoping review by Xinming Yang, Xinming Yang, Bo Li, Bo Li, Bo Li, Linna Wu, Ying Cui, Ying Cui

    Published 2025-04-01
    “…A comprehensive search of databases, including PubMed, Web of Science, MEDLINE, and Embase, was conducted, including 79 studies on acupuncture interventions for VCI. …”
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    Article
  17. 1857

    EPAS1 amplifies asthma pathogenesis through JAK2/STAT3-mediated ferroptosis and inflammation by Lili Liu, Cheng Yang, Yan Li, Hao Zhou, Mei Shi, Tiantian Shi, Weibing Shi

    Published 2025-03-01
    “…Additionally, immune cell infiltration in asthma patients was analyzed using the Immune Cell AI database in relation to ferroptosis-related genes. Functional experiments at the cellular level were conducted to assess the effects of key genes on cell viability, inflammation, and ferroptosis. …”
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  18. 1858
  19. 1859

    RNA-Seq analysis reveals the long noncoding RNAs associated with immunity in wild Myotis myotis bats by Sebastien Riquier, Samuel Carthy, Graham M. Hughes, Frederic Touzalin, Wilfried Haerty, Zixia Huang, Emma C. Teeling

    Published 2025-04-01
    “…Our network analysis revealed significant variation in immune status among a subset of individuals, potentially due to pathogenic conditions. …”
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  20. 1860

    Multi-feature fusion RFE random forest for schizophrenia classification and treatment response prediction by Chang Wang, Rui Zhang, Jiyuan Zhang, Yaning Ren, Ting Pang, Xiangyu Chen, Xiao Li, Zongya Zhao, Yongfeng Yang, Wenjie Ren, Yi Yu

    Published 2025-03-01
    “…Initially, we computed multiple features, such as regional homogeneity, fractional amplitude of low-frequency fluctuations, and functional connectivity. Subsequently, the RFE-RF method was employed to conduct SZ classification. …”
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