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Identifying Common Diagnostic Biomarkers and Therapeutic Targets between COPD and Sepsis: A Bioinformatics and Machine Learning Approach
Published 2025-05-01“…Functional enrichment analyses were conducted to explore the biological roles of these genes. …”
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1803
Associations Between Obstructive Sleep Apnea and Metabolic Dysfunction-Associated Fatty Liver Disease: Insights from Comprehensive Mendelian Randomization and Gene Expression Analy...
Published 2025-07-01“…Functional enrichment (GO and KEGG), protein–protein interaction (PPI) networks, and immune cell infiltration analyses (ssGSEA) were performed on the intersecting genes. …”
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1804
Novel Clinical Insights into the Pathogenesis of Posttraumatic Elbow Stiffness: An Expression Profile Analysis of Contracted Joint Capsule in Human
Published 2025-01-01“…Differentially expressed genes (DEGs), microRNAs, and long non-coding RNAs (LncRNAs) were identified and analyzed. Functional enrichment analysis was performed, and the associated protein–protein interaction (PPI) network was constructed. …”
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Effect of restrictive fluid resuscitation on severe acute kidney injury in septic shock: a systematic review and meta-analysis
Published 2025-02-01“…Severe AKI was defined as the AKI network score 2–3 or Kidney Disease Improving Global Outcomes stages 2 and 3.Data extraction and synthesis Two independent reviewers used standardised methods to search, screen and code included trials. …”
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Enhancing access to specialist appointments in tertiary healthcare in Shanghai, China: a structured reservation pathway using digital health technologies
Published 2024-12-01“…The outcome analysis employed a mixed-methods approach, integrating quantitative analysis with statistical and machine learning techniques, including multivariate logistic regression, random forest (RF) and artificial neural network (ANN) analysis.Setting This study was conducted at Renji Hospital, a premier general tertiary care institution in Shanghai, China, where the innovative PRP system was implemented. …”
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Nanoengineered polyaniline/carbon black VXC 72 hybridized with woven abaca for superior electromagnetic interference shielding
Published 2025-04-01“…This study investigates the electromagnetic (EM) shielding properties of Polyaniline (PAni)-functionalized woven abaca fibers, reinforced with Carbon Black (CB) VXC 72, in the ultrahigh-frequency (UHF) range (500–4500 MHz), as determined using Vector Network Analyzer (VNA). …”
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Towards Smart Pest Management in Olives: ANN-Based Detection of Olive Moth (<i>Prays oleae</i> Bernard, 1788)
Published 2025-06-01“…This study aims to develop a functional model based on an artificial neural network to detect olive moths in real time. …”
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Endovascular Treatment of a Patient with Multivessel Deсease Combined with Chronic Occlusion of the Right Coronary Artery
Published 2022-10-01“…Thanks to the accumulated experience and advanced technologies, the success rate of recanalization has reached 90–95 %, and complications are not more common than in cases of stenting of non-occlusive lesions. The conducted studies have proved that successful recanalization of CCO improves the patient’s clinical and functional status, intracardiac hemodynamics and quality of life.Conclusion. …”
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Exploring the associations of plasma proteins with frailty based on Mendelian randomization
Published 2024-12-01“…Protein-protein interaction network construction and gene ontology functional enrichment analysis were conducted based on MR-identified target proteins. …”
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Consumption of only wild foods induces large scale, partially persistent alterations to the gut microbiome
Published 2025-05-01“…Samples were profiled by 16S rRNA sequencing, and oligotyping and network analysis were conducted to assess microbial co-occurrence patterns. …”
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CD27 as a Diagnostic Biomarker and Its Role in Immune Heterogeneity and Predicting Clinical Drug Responses in Hashimoto’s Thyroiditis
Published 2024-12-01“…Yan-ming Dong, Guo-qiang Bao Department of General Surgery, The Second Affiliated Hospital of Air Force Medical University, Xi’an, Shaanxi Province, People’s Republic of ChinaCorrespondence: Guo-qiang Bao, Department of General Surgery, The Second Affiliated Hospital of Air Force Medical University, No. 356 of Xinsi Road, Baqiao District, Xi’an, Shaanxi Province, People’s Republic of China, Tel +86 13891430409, Email baoguoqiang_ln@163.comObjective: To identify key genes and potential molecular mechanisms associated with Hashimoto’s thyroiditis (HT) to provide new insights for the development of diagnostic and therapeutic targets for this disease.Methods: Differential expression analysis and weighted gene co-expression network analysis (WGCNA) were conducted to identify the differentially expressed genes (DEGs) associated with HT. …”
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A Decision Support System for Optimal Building Cold Source Selection
Published 2022-01-01“…Therefore, this paper proposes a new decision-making system, which is based on value engineering (VE) and combined with analytic network process (ANP) to conduct a comprehensive study of project decision-making. …”
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Extracellular matrix remodeling fibroblasts govern the tumor microenvironment disparity between adenomatous lesions and adenocarcinoma in gallbladder
Published 2025-07-01“…Additional analyses such as protein-protein interaction network, immune infiltrate analysis, high-dimensional weighted gene co-expression network analysis, and cell-cell communication analysis were also performed. …”
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Enhancing Wind Turbine Power Output Estimation Using Causal Inference and Adaptive Neuro-Fuzzy Inference System ANFIS
Published 2025-04-01“…Various practical experiments were conducted using different membership functions in neuro-fuzzy training to achieve the lowest possible mean square error. …”
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Anticoagulant effects, substance basis, and quality assessment approach of Aspongopus chinensis Dallas.
Published 2025-01-01“…Furthermore, animal experiments were conducted to measur coagulation factors and assess the in vivo anticoagulant activity.…”
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Spatially resolved transcriptomic signatures of hippocampal subregions and Arc-expressing ensembles in active place avoidance memory
Published 2024-10-01“…The rodent hippocampus is a spatially organized neuronal network that supports the formation of spatial and episodic memories. …”
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Mechanisms of Amomum villosum essential oil in enhancing tilapia (Oreochromis niloticus) intestinal health
Published 2024-12-01“…Hmgb2, Parp11, Bcoll is considered to be the key genes, and has the immune regulation function. This study provides new insights into the molecular basis underlying the protective effects of dietary EOA in tilapia. …”
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Bringing a Systems Approach to Living Donor Kidney Transplantation
Published 2024-10-01Get full text
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