Bioinformatics analysis of oxidative phosphorylation-related differentially expressed genes in osteoporosis by Songmao Wang, Yaling Wang, Minfeng Gan, Lei Wan, Yapu Liu, Yonghui Xu, Zhenxing Hou, Yongkang Deng, Xuejian Wu

“…Correlation analysis, Protein–Protein Interaction (PPI) network construction, mRNA-miRNA, mRNA-TF interaction network construction, and immune infiltration analysis using CIBERSORT were also conducted. …”
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Unveiling shared therapeutic targets and pathological pathways between coronary artery disease and major depressive disorder through bioinformatics analysis by Mengyun Hu, Rong Tan, Caihong Lu, Ting Zhou, Qin Wang, Tao Liu

“…However, the shared mechanisms and therapeutic targets for CAD and MDD remain incompletely comprehended. Functional enrichment analyses were conducted to investigate the pathways associated with the differentially expressed genes (DEGs) in the CAD and MDD datasets. …”
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Machine learning-enabled multiscale modeling platform for damage sensing digital twin in piezoelectric composite structures by Somnath Ghosh, Saikat Dan, Preetam Tarafder

“…A parametrically upscaled coupled constitutive damage mechanics (PUCCDM) model is developed for this DT with the representation of microstructural morphology and mechanisms in macroscopic constitutive relations. Artificial neural network operates on micro-electro-mechanical data to derive PUCCDM constitutive coefficients as functions of underlying representative aggregated microstructural parameters (RAMPs). …”
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Identification and evaluation of metabolic mRNAs and key miRNAs in colorectal cancer liver metastasis by Guanxuan Chen, Shiwen Wang, Meng Zhang, Wenna Shi, Ruoyu Wang, Wanqi Zhu

“…We screened the featured genes using a machine-learning technique, followed by an evaluation of their diagnostic potential for CRC liver metastasis. Additionally, we conducted a functional enrichment analysis and constructed a network of miRNA-targeted mRNAs. …”
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Yinzhihuang Oral Liquid Alleviates Intrahepatic Cholestasis of Pregnancy: Integrated Bioinformatics and Experimental Mechanistic Insight by Ting Liu, Xinrun Zhuang, Wei Gu, Wei Liu, Jin Zhang, Weijian Zeng, Jue Li, Yang Pan

“…ICP-related targets were gathered from multiple databases, and hub genes were selected through bioinformatics and previously identified differentially expressed proteins. Functional annotation and pathway enrichment analyses were conducted, with validation in TCA-induced cells treated with various YZH concentrations (0.1%–5.0%) compared to controls. …”
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A Pan-Cancer Analysis of Natriuretic Peptide Receptor 3 (NPR3) with Clinical Cohort and in vitro Validation by Liu Y, Liu J, Li Y, Zhao Z, Lyu D, Dong K, Wei M, Huang R, Lu B, Pan X

“…Cell-based experiments in 786-O, 769-P, and A-498 cell lines were further conducted.Results: In pan-cancer, NPR3 was down-regulated in most of the tumor types, and ceRNA and PPI network were constructed. …”
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Neuroimaging insights into the psychosocial impact of the COVID-19 pandemic: a systematic review by Yiling Guo, Nanfang Pan, Yuhan Zou, Yajing Long, Xun Zhang, Qingyuan Li, Xueling Suo, Manpreet K. Singh, Song Wang, Qiyong Gong

“…However, neural substrates underlying mental health vulnerabilities brought by the pandemic remain elusive. We conducted a systematic review relating structural and functional brain abnormalities to mental health issues associated with COVID-19 at brain regional and network levels. …”
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Research on Optimized Algorithm for Deep Learning Based Recognition of Sediment Particles in Turbulent Flow by WANG Hao, YANG Feiqi, ZHANG Lei, WU Wei, XIE Haonan, ZHAO Lin

“…The YOLOv5 deep learning network structure is enhanced by improving convolutional blocks, incorporating attention mechanisms, and optimizing loss function processing, boosting the detector's overall performance in accurately capturing the motion of particles over short distances. …”
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Multi-bioinspired electronic skins with on-demand adhesion and opto-electronic synergistic display capabilities by Wenzhao Li, Jinbo Li, Xiaoya Ding, Qitao Tan, Weijian Sun, Puxiang Lai, Yuanjin Zhao

“…Our electronic skins are composed of a stretchable polyurethane (PU) inverse opal film integrated with a carbon nanotube (CNT)-hybridized polyacrylamide (PAAm)-gelatin double-network-hydrogel conductive flexible substrate and a temperature-responsive poly(N-isopropylacrylamide) (PNIPAm) octopus-inspired hemispherical adhesive array. …”
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Bioinformatics analysis based on microarray data reveals molecular crosstalk and immune relationship between sarcopenia and atherosclerosis by Jinghong Yang, Jun Zhong, Yimin Du, Jialin Liu, Zhong Li, Yanshi Liu

“…We employed multiple statistical methods and bioinformatics tools to identify shared differentially expressed genes (DEGs). Subsequently, we conducted functional enrichment analysis, protein-protein interaction analysis, and TF-gene interaction network analysis, as well as TF-miRNA coregulatory network analysis. …”
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Organic Amendments Enhance Agroecosystem Multifunctionality via Divergent Regulation of Energy Flow Uniformity in Soil Nematode Food Webs by Tianyuan Huang, Jinghua Huang, Jing Zhang, Guoqing Li, Shiwei Zhao

“…Using high-throughput sequencing and energy flux modeling, we found that straw and biochar enhanced nematode diversity and co-occurrence network complexity, while liquid organic fertilizer reduced network complexity. …”
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Water Properties of Soft Contact Lenses: A Comparative Near-Infrared Study of Two Hydrogel Materials by Jelena Munćan, Ivana Mileusnić, Jovana Šakota Rosić, Aleksandra Vasić-Milovanović, Lidija Matija

“…The functionality of soft contact lenses depends strongly on the water content and their water-transport ability. …”
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Investigation of the electrical quality and long-term stability of aluminum ground stud connections in automotive applications by Viktor Haak, Keke Yang, Gerson Meschut

“…The rapid advancement in the electrification of modern vehicles has led to a continuous increase in electrical consumers for various comfort and safety functions. Ground studs serve as the electrical interface between the conductive vehicle body and the onboard network. …”
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PI3K/AKT signaling pathway plays an important role in the pathogenesis of metabolic dysfunction-associated steatotic liver disease by Cuiping Shao, Youqing Xu

“…Differentially expressed genes (DEGs) were identified via the limma package in R (|logFC|> 1, adjusted p value < 0.05). Functional enrichment analysis was conducted via Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways and gene set enrichment analysis (GSEA). …”
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Enhanced SVM-based model for predicting cyberspace vulnerabilities: Analyzing the role of user group dynamics and capital influx. by Yicheng Long

“…Performance evaluations are conducted on both datasets using cross-validation. …”
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The State and Features of the Media Culture of Modern Youth by O. P. Gorbat

“…An attempt is made to systematize these properties – the priority of communication through social networks, listening and browsing media files, turning to online games, running a network business, are called the most characteristic ones. …”
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Composition of Innovative Activity’ Parameters for a System of Analysis and Making Decision in the Innovations by Irina Anatolyevna Razumova, Nadezhda Nikolaevna Pokrovskaya, Lilia Vilyevna Akhmerova

“…Given the complexity, diversity and versatility of innovation and of functioning of modern economy, the most effective approach to solve this problem is the use of modern technologies, in particular, artificial intelligence to solve this problem. …”
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Rapid paralysis and hidden malignancy: acute motor axonal neuropathy revealing pleomorphic liposarcoma by Sathish Kumar Krishnan, Vijaya Sivalingam Ramalingam, Melissa Johnson

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Model Predictive Control With Reinforcement Learning-Based Speed Profile Generation in Racing Simulator by Min-Seong Kim, Tae-Hyoung Park

“…Polynomial functions are employed to reduce the dimensionality of the network output in velocity profile design. …”
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Short-term and long-term outcomes of hybrid revascularisation procedures in peripheral artery disease: a systematic review protocol by Lewis Meecham, Maram Darwish, Huw Owain Davies, Emily Morgan

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