A phase 1 clinical trial of the sigma‐2 receptor complex allosteric antagonist CT1812, a novel therapeutic candidate for Alzheimer's disease by Michael Grundman, Roger Morgan, Jason D. Lickliter, Lon S. Schneider, Steven DeKosky, Nicholas J. Izzo, Robert Guttendorf, Michelle Higgin, Julie Pribyl, Kelsie Mozzoni, Hank Safferstein, Susan M. Catalano

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Circ 0020938 inhibits hair follicle stem cells proliferation via the miR-142-5p/DSG4 axis in cashmere goats by Jiamian Du, Menghua Sui, Zhihao Song, Shuangshuang Liang, Yujie Zheng, Xin Wang

“…The functional assays were performed to assess the effect of circ 0020938 on hair follicle stem cells (HFSCs) proliferation. …”
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FEN1 plays a key role in the transition from HSIL to CSCC by Fengxian Zhang, Xiaomei Chen, Chenyang Chu, Meilin Chen, Ying Yang, Yanting You, Jie Zhou, Pingping Jiang, Ni Song, Yunhong Yu, Yanyan Liu

“…In vitro experiments were conducted to investigate the function and underlying mechanisms of FEN1 in HSIL and CSCC. …”
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The Risk of Vestibular Disorders with Semaglutide and Tirzepatide: Findings from a Large Real-World Cohort by Eman A. Toraih, Awwad Alenezy, Mohammad H. Hussein, Shahmeer Hashmat, Saitej Mummadi, Nawaf Farhan Alrawili, Ahmed Abdelmaksoud, Manal S. Fawzy

“…<b>Methods</b>: Using the TriNetX research network (accessed 3 November 2024), we conducted a retrospective cohort study of adults prescribed semaglutide (<i>n</i> = 419,497) or tirzepatide (<i>n</i> = 77,259) between January 2018 and October 2024. …”
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MSFA-YOLO: A Multi-Scale SAR Ship Detection Algorithm Based on Fused Attention by Zhao Liangjun, Ning Feng, Xi Yubin, Liang Gang, He Zhongliang, Zhang Yuanyang

“…Leveraging the excellent feature representation capabilities of neural networks, deep learning methods have been widely adopted for object detection in synthetic aperture radar (SAR) images. …”
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Enhanced deep learning model for apple detection, localization, and counting in complex orchards for robotic arm-based harvesting by Tantan Jin, Xiongzhe Han, Pingan Wang, Zhao Zhang, Jie Guo, Fan Ding

“…Specifically, an optimized You Only Look Once (YOLO) v8n model was developed by integrating a dilation-wise residual–dilated re-parameterization block module, a generalized feature pyramid network, and the Scylla Intersection-over-Union loss function. …”
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YOLO-MECD: Citrus Detection Algorithm Based on YOLOv11 by Yue Liao, Lerong Li, Huiqiang Xiao, Feijian Xu, Bochen Shan, Hua Yin

“…At last, the MPDIoU loss function was employed, resulting in improved bounding box detection accuracy and accelerated model convergence. …”
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Efficacy and safety of Chinese patent medicines for allergic rhinitis based on 2020 Chinese Pharmacopoeia: a protocol for systematic review and meta-analysis of randomized controll... by Weibo Zhao, Lingyao Kong, Xuehui Wang, Qingyuan Liu, Yaqi Wang, Ji Wang

“…Unlike existing reviews, this study emphasizes rigorous standards of TCPMs, aiming to provide a more reliable evidence base. Although a network meta-analysis would be ideal, a traditional meta-analysis will be conducted due to limited data. …”
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De novo assembly of plasmodium interspersed repeat (pir) genes from Plasmodium vivax RNAseq data suggests geographic conservation of sub-family transcription by Timothy S. Little, Deirdre A. Cunningham, George K. Christophides, Adam James Reid, Jean Langhorne

“…Abstract Background The plasmodium interspersed repeats (pir) multigene family is found across malaria parasite genomes, first discovered in the human-infecting species Plasmodium vivax, where they were initially named the virs. Their function remains unknown, although studies have suggested a role in virulence of the asexual blood stages. …”
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Fabricating ultra-robust hydrogels with adhesive properties by restraining crack propagation with bamboo cellulose-based carbon nanomaterials by Xin Duan, Huanxin Huo, Hongshan Li, Yihong Gao, Haoran Shi, Feng Kuang, Yumeng Chen, Jianyong Wan, Jingjie Shen, Guanben Du, Long Yang

“…The bamboo fiber functionalized with phthalic anhydride underwent carbonization, yielding bamboo cellulose-derived carbon nanomaterials (C-BCN). …”
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Presentation Attack Detection using iris periocular visual spectrum images by Andrés Valenzuela, Juan E. Tapia, Violeta Chang, Christoph Busch

“…Additionally, we improved the CNN results by integrating the ArcFace loss function instead of the traditional categorical cross-entropy loss, highlighting that the ArcFace function enhances the performance of the models for both regions of interest, facial and iris periocular areas. …”
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An Effective Tree-Structured AI Model for Reducing Overhead of Life Cycle Management in Wireless Communication by Yingshuang Bai, Zhaohui Huang, Chen Sun, Yujie Zhang, Tao Cui, Samuel Atungsiri

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Multi-omics Analysis of Histone-related Genes in Osteosarcoma: A Multidimensional Integrated Study Revealing Drug Sensitivity and Immune Microenvironment Characteristics by Yang Yang MD, Xinqiao Tang MD, Zhong Liu MD

“…Additionally, we conducted functional enrichment analysis, immune characteristics analysis, and drug sensitivity prediction. …”
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Exploration of the shared gene signatures and molecular mechanisms between cardioembolic stroke and ischemic stroke by Xuan Wang, Xuan Wang, Xueyuan Liu, Xueyuan Liu

“…Protein-protein interaction (PPI) network and topology analyses were conducted to identify the core shared genes. …”
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A Systematic Review of Using Deep Learning Technology in the Steady-State Visually Evoked Potential-Based Brain-Computer Interface Applications: Current Trends and Future Trust Met... by A. S. Albahri, Z. T. Al-qaysi, Laith Alzubaidi, Alhamzah Alnoor, O. S. Albahri, A. H. Alamoodi, Anizah Abu Bakar

“…The first category, convolutional neural network (CNN), accounts for 70% (n=21/30). The second category, recurrent neural network (RNN), accounts for 10% (n=3/30). …”
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An Improved Differential Evolution Algorithm for a Multicommodity Location-Inventory Problem with False Failure Returns by Congdong Li, Hao Guo, Ying Zhang, Shuai Deng, Yu Wang

“…False failure returns are returned products that have no functional or cosmetic defects, and they represent a large body of customer returns in practice. …”
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ContDataQC: An R package and Shiny app for quality control of continuous water quality sensor data by Michael J. Pennino, Jen Stamp, Erik W. Leppo, David A. Gibbs, Britta G. Bierwagen

“…In this paper, we describe the main functions of ContDataQC and discuss how it is being applied in long-term regional monitoring networks for streams and lakes. …”
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Developing and validation of religious education curriculum in preschool by Zeinab Ashrafi Soltan-Ahmadi, Sadegh Maleki Avarsin, Javad Keyhan, jahangir yari

“…In addition to the role and function of the family as an effective and important factor in children's issues and problems (Abbass Ghorbani & Naghdi, 2020), today the role of educational systems, especially education, is not limited only in learning science, developing skills, cognitive abilities, and preparing children and teenagers to entering higher education degrees, but its cultural and educational function is very important in the progress and development of societies (Nasiri et al, 2022). …”
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Electret‐Inspired Charge‐Injected Hydrogel for Scar‐Free Healing of Bacterially Infected Burns Through Bioelectrical Stimulation and Immune Modulation by Mujie Liu, Yuheng Wang, Haodong Wang, Lihong Qi, Yuxuan Shang, Jiajie Song, Xiulong Feng, Yiwei Chen, Waqar Ali Memon, Yuping Shen, Xiaodong Wu, Jiangbei Cao, Yifan Zhao, Zhuangde Jiang, Dingxin Liu, Shareen Shafique, Shengtao Li, Guanghao Lu, Zhixiang Wei, Zhijie Liu, Kun Zhou, Yuping Quan, Xiaoyu Zhang, Xin Zou, Xuefeng Wang, Na Liu, Yaqing Zhang, Yiwei Hu, Chao Han, Wen Wang

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Pathophysiological mechanisms of integrated regulation of water-sodium homeostasis: from cellular dysfunction of Na-K-ATPase to dysregulation of systemic volume control: a systemat... by Anatoliy Gozhenko, Walery Zukow, Olena Gozhenko, Mykhailo Saensus, Oleksandr Vitiukov

“… Background: Water-sodium homeostasis regulation is a fundamental physiological process that ensures cellular function maintenance, extracellular fluid volume, and arterial pressure. …”
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