Quercetagetin alleviates inflammatory osteoclastogenesis and collagen antibody-induced arthritis via Nrf2 signaling and Pten/AKT/Nfatc1 axis by Haojue Wang, Tao Yuan, Jingpeng Wang, Dengju Li, Wayne Yuk-wai Lee, Ziqing Li, Shui Sun

“…This study was designed to elucidate the potential associations between Quercetagetin and RA, establishing the therapeutic potential of Quercetagetin and related mechanisms in RA treatment. Methods Network pharmacology was conducted to decipher related targets and signaling pathways between Quercetagetin and RA. …”
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RNA-seq analysis reveals key genes associated with downregulation of APE1 in esophageal squamous cell carcinoma by Alan Chu, Xiao Liu, Shijia Liu, Mengxi Li, Rui Song, Lanlan Gan, Yongtai Wang, Zongwen Liu, Chen Sun

“…TE-1 cells with APE1 knockout were used for transcriptome sequencing (RNA sequencing, RNA-Seq) detection, and GO and KEGG enrichment analysis of differentially expressed genes was conducted. Protein-protein interaction (PPI) network analysis was performed on the genes in the intersection of differential genes between the two sequencing datasets. …”
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In Situ Synthesis of CoMoO₄ Microsphere@rGO as a Matrix for High-Performance Li-S Batteries at Room and Low Temperatures by Ronggang Zhang, Haiji Xiong, Jia Liang, Jinwei Yan, Dingrong Deng, Yi Li, Qihui Wu

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Exploring the role of mitochondrial metabolism and immune infiltration in myocardial infarction: novel insights from bioinformatics and experimental validation by Jingyi Hou, Jingyi Hou, Jingyi Hou, Lihan Wang, Lihan Wang, Naiqiang Zhu, Xueli Li

“…Experimental validation of hub mitoDEGs, immune cell markers (F4/80, CD163 and CD86), and apoptosis-related proteins (BAX/BCL-2 and cleaved caspase-3) was conducted in MI mice, and the association with cardiac function was explored.ResultsMitoDEGs in the MI group were significantly enriched in pathways related to mitochondrial transport and gene expression. …”
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mHealth Apps Available in Italy to Support Health Care Professionals in Antimicrobial Stewardship Implementation: Systematic Search in App Stores and Content Analysis by Giuseppa Russo, Annachiara Petrazzuolo, Marino Trivisani, Giuseppe Virone, Elena Mazzolini, Davide Pecori, Assunta Sartor, Sergio Giuseppe Intini, Stefano Celotto, Rossana Roncato, Roberto Cocconi, Luca Arnoldo, Laura Brunelli

“…Lower scores were achieved for AMS (8%), pathogens and etiological agents (4%), notes and records (3%), network (2%), AMR (1%), and dashboard function (1%). …”
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Identification of genes related to fatty acid metabolism in type 2 diabetes mellitus by Ji Yang, Yikun Zhou, Jiarui Zhang, Yongqin Zheng, Jundong He

“…Differential expression analysis, WGCNA, machine learning algorithms, diagnostic analysis, and validation were employed to identify key feature genes. Functional analysis, ceRNA network construction, immune microenvironment assessment, and drug prediction were conducted to explore the underlying molecular mechanisms. …”
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Yo3RL-Net:A fusion of two-phase end-to-end deep net framework for hand detection and gesture recognition by Xiang Wu, Yuanhao Ma, Shijie Zhang, Tianfei Chen, He Jiang

“…For the gesture recognition phase, we suggest utilizing a method that combines a three-dimensional residual network with a long short-term memory (LSTM) network. …”
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Impact of Exercise Training in Patients with Diabetic Peripheral Neuropathy: An Umbrella Review by Alba Gracia-Sánchez, Adriana López-Pineda, Rauf Nouni-García, Sara Zúnica-García, Esther Chicharro-Luna, Vicente F. Gil-Guillén

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A Throughput Analysis Using a Non-Saturated Markov Chain Model for LTE-LAA and WLAN Coexistence by Mun-Suk Kim

“…The LTE-LAA system ensures efficient coexistence with other existing unlicensed systems by incorporating listen-before-talk functionality and conducting random backoff operations similar to those in the IEEE 802.11 distributed coordination function. …”
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A multi-objective metaheuristic method for node placement in dynamic IoT environments by Farzad Kiani

“…A newly developed multi-objective fitness function optimizes critical metrics such as coverage, energy efficiency, connectivity, and redundancy. …”
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Architecture as Interface: Connection, Disruption, Breakdown by Liubov I. Iakovleva

“…The article analyzes architecture as a special interface, presenting the concept of interface through the functions of linking and separating. These functions manifest themselves in various types of architectural space organization: firstly, as intermediary connecting residents with their culture and living space, and secondly, in the image of a smart home connecting the body, imagination, and technologies of the house into a single, continuous network. …”
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A Resilient micro-payment infrastructure: an approach based on blockchain technology by Soumaya Bel Hadj Youssef, Noureddine Boudriga

“…Finally, a numerical simulation is conducted to assess the performance of the infrastructure. …”
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Cross-fusion activates deep modal integration for multimedia recommendation. by Chong Zhang, ZhiCai Zhang

“…This method adds a cross-fusion module to fuse the features of different modalities through deep-feature fusion. A fusion loss function is further proposed to improve the recommendation performance of the network. …”
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Gene expression profiling of extraocular muscles in primary inferior oblique overaction by Rui Hao, Yuchuan Wang, Wei Zhang

“…Methods Transcriptome sequencing was conducted on EOMs from ten patients with primary IOOA and ten patients with secondary IOOA. …”
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Cortical representation of novel tool use: Understanding the neural basis of mechanical problem solving by Clara Seifert, Thabea Kampe, Cilia Jäger, Jennifer Randerath, Afra Wohlschläger, Joachim Hermsdörfer

“…Methods: An event-related fMRI study including 22 participants was conducted. During scanning, participants had to manipulate novel tools, the function of which they could infer by mechanical problem solving. …”
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Efficient and Effective NDVI Time-Series Reconstruction by Combining Deep Learning and Tensor Completion by Ang Li, Menghui Jiang, Dong Chu, Xiaobin Guan, Jie Li, Huanfeng Shen

“…Multidimensional gradient constraints are introduced in the loss function to retain critical information. The experiments conducted on moderate resolution imaging spectroradiometer NDVI data show that the NIT-Net framework is superior to most of the comparison methods. …”
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Synergistic effects of notoginsenoside R1 and saikosaponin B2 in atherosclerosis: A novel approach targeting PI3K/AKT/mTOR pathway and macrophage autophagy. by Yihua Wang, Qing Liao, Xue Mei, Han Xu, Lijun Luo, Rong Huang, Yue Tang, Chunyang Zhou

“…Firstly, we employed network pharmacology analysis to identify 113 common targets, including mTOR and CASP3, for NGR1, SSB2, and atherosclerosis from databases such as TCMSP. …”
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Synergistic effect of artificial intelligence and new real-time disassembly sensors: Overcoming limitations and expanding application scope by Bozhou Li, Dajiang Ju, Xingwang Li, Yan Liu, Hongru He, Hao Wang

“…Then, based on the gated recurrent unit (GRU) model, the article applied the particle swarm optimization (PSO) algorithm to optimize the parameters of the GRU network and used the support vector machine (SVM) model to optimize the classification function of the network output. …”
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LDDFSF-YOLO11: A Lightweight Insulator Defect Detection Method Focusing on Small-Sized Features by Peng Shen, Keyu Mei, Huiqiong Cao, Yongxiang Zhao, Guoqing Zhang

“…And optimize the network structure through channel pruning technology to improve model lightweighting. …”
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Investigating the role and mechanisms of bisphenol compounds in premature ovarian insufficiency using computational biology and bioinformatics by Deshui Kong, Yufei Nie, Haojie He, Hongyan Guo

“…Using bioinformatics tools, we identified potential target genes related to both bisphenols and POI, and conducted functional enrichment analysis. Further, we calculated differentially expressed genes for POI, extracted core networks, and explored immune function and screened core genes. …”
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