Cranberry-derived bioactives for the prevention and treatment of urinary tract infections: antimicrobial mechanisms and global research trends in nutraceutical applications by Himanshu Jangid, Amrullah Shidiki, Gaurav Kumar, Gaurav Kumar

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Healthcare professionals’ views on healthcare-related factors influencing symptom course in persistent somatic symptoms: a qualitative study of four European countries by Aleksandra Kustra-Mulder, Brodie McGhie-Fraser, Tara Petzke, Karolina Fila-Pawłowska, Judith Rosmalen, Fiammetta Cosci, Bernd Löwe, Angelika Weigel

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Establishing the best step-up treatments for children with uncontrolled asthma despite inhaled corticosteroids: the EINSTEIN systematic review, network meta-analysis and cost-effec... by Sofia Cividini, Ian Sinha, Giovanna Culeddu, Sarah Donegan, Michelle Maden, Katie Rose, Olivia Fulton, Dyfrig Hughes, Stephen Turner, Catrin Tudur Smith

“…We assessed the Risk Of Bias using the Cochrane Risk Of Bias tool and carried out Bayesian meta-analyses, network meta-analysis and network meta-regression, including treatment by covariate (age, sex, ethnicity, eczema, eosinophilia, asthma severity) interactions. …”
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Deep Defense Against Mal-Doc: Utilizing Transformer and SeqGAN for Detecting and Classifying Document Type Malware by Gati Lother Martin, Sang-Min Lee, Jong-Hyun Kim, Young-Seob Jeong, Ah Reum Kang, Jiyoung Woo

“…Subsequently, we design a Transformer-based model for document malware detection and family classification. Detection is conducted at both the stream and file levels. To solve the class imbalance issue in the malware family, we utilize a generative adversarial network to generate malware samples. …”
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Research on VoNR voice wireless optimization strategy by Xinchao ZANG, Ronglin LI

“…There are two 5G voice solutions, EPS Fallback and VoNR.In the early stage of 5G network construction, 5G base station coverage rate and terminal penetration rate were not high, so EPS Fallback was used as a 5G voice transition solution.At present, with the deployment of 2.6 GHz and 700 MHz networks, the SA network achieves independent networking, and VoNR will be the main solution for 5G voice.In order to actively respond to the deployment of VoNR and analyze the advantages of VoNR from multiple dimensions, an in-depth research on VoNR features, parameters, and application scenarios were conducted, VoNR wireless strategy deployment was formulated, for uplink weak field, interference, large traffic characteristics of all kinds of scenarios functions such as deployment and optimization to provide suggestion and scheme, and prepares for VoNR’s official commercial use.…”
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Optimizing VGG16 deep learning model with enhanced hunger games search for logo classification by Mohammed Hussain, Thaer Thaher, Mohamed Basel Almourad, Majdi Mafarja

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Decoding per- and polyfluoroalkyl substances (PFAS) in hepatocellular carcinoma: a multi-omics and computational toxicology approach by Yanggang Hong, Deqi Wang, Zeyu Liu, Yuxin Chen, Yi Wang, Jiajun Li

“…Molecular docking simulations were conducted to assess the binding affinities between PFAS compounds and selected target proteins. …”
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Effects of pharmacological and non-pharmacological interventions for the management of sleep problems in people with fibromyalgia: a multi-methods evidence synthesis by Mari Imamura, Clare Robertson, Jemma Hudson, Daniel Whibley, Lorna Aucott, Katie Gillies, Marcus Beasley, Martin J Stevens, Paul Manson, Debra Dulake, Abhishek Abhishek, Nicole KY Tang, Gary J Macfarlane, Miriam Brazzelli

“…A risk-of-bias assessment of included RCTs was conducted using the Cochrane Risk of Bias tool. We used the CINeMA approach based on the Grading of Recommendations Assessment, Development and Evaluation framework to evaluate the certainty of the evidence included in the network meta-analysis (NMA) assessing sleep quality. …”
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The promotion mechanism of how biochar affects the reclaimed soil microbial carbon sequestration capacity in coal mining areas by Jing MA, Ming ZOU, Zhanbin LUO, Yanfeng ZHU, Yongjun YANG, Fu CHEN

“…This study applied three kinds of biochar originated from straw containing rice straw, wheat straw, and corn straw to mine reclaimed soil, measured the effects of biochar addition on the physicochemical properties, enzyme activity, and carbon management index of reclaimed soil, and analyzed the variation of soil microbial community structure and carbon sequestration functional genes. From the experimental results, the main conclusions are shown as follows: ① The soil pH, electrical conductivity, ammonium nitrogen, nitrate nitrogen, available phosphorus, and available potassium content in the biochar-added groups significantly increased (P < 0.05), and the activities of β-glucosidase (BG), cellobiohydrolase (CBH), and leucine aminopeptidase (LAP) were enhanced, whereas the activity of β–N-acetylglucosaminidase (NAG) decreased by 15.0% to 25.0%. ② Biochar addition increased the α diversity index of soil microbial community, while the effect on bacterial α diversity index was significantly higher than that of fungi. …”
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Exploring the biological functions and immune regulatory roles of IRAK3, TNFRSF1A, CX3CR1, and JUNB in T2DM combined with MAFLD: integrated bioinformatics and single-cell analysis by Qin Wang, Xiaoqi Li, Kaidierdan Wushoulaji, Jinyang Wang, Li Wan, Ye Yang, Xueli Gong

“…Functional enrichment analysis, immune infiltration analysis, and validation of gene significance in T2DM combined with MAFLD progression were conducted using animal experiments to understand the biological functions and immunomodulatory roles of key biomarkers. …”
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A Hybrid Strategy-Improved SSA-CNN-LSTM Model for Metro Passenger Flow Forecasting by Jing Liu, Qingling He, Zhikun Yue, Yulong Pei

“…To address the issues of slow convergence and large errors in existing metaheuristic algorithms when optimizing neural network-based subway passenger flow prediction, we propose the following improvements. …”
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Reliability analysis of freight elevator systems based on FFMEC, FTA and BN by Jie Yu, Juyong Zhang, Chunguang Li, Zhiping Chen, Chaoliang Huang

“…The fuzzy function was designed according to the characteristics of parameters Severity (S), Occurrence (O) and Detection (D), and the Fuzzy Risk Priority Number (FRPN) are calculated and ranked to identify high-risk failure modes. …”
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A BERT-Based Classification Model: The Case of Russian Fairy Tales by Валерий Дмитриевич Соловьев, Марина Ивановна Солнышкина, Andrey Ten, Николай Аркадиевич Прокопьев

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Does the alternating timing of rTMS combined with soft-hand rehabilitation robot affect the recovery of hand function in patients after stroke? A study protocol for a multicentre r... by Ying Shen, Jiang Xu, Ting Zhou, Xinyue Wang, Hongxing Wang, Wenjun Dai, Chuan Guo, Xuejing Li, Xiaobing Chen, Kai Leng Catherine Chan, Fei Lu, Qinglun Su

“…The objective of this study is to evaluate the efficacy of alternating rTMS and soft-hand rehabilitation robot therapy to enhance upper limb and hand function in patients with ischaemic stroke.Methods and analysis This multicentre study will be conducted as a single-blind, controlled, randomised trial, enrolling 132 post-stroke patients with a disease duration ranging from 1 week to 3 months. …”
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Identifying Inhibitor-SARS-CoV2-3CL^pro Binding Mechanism Through Molecular Docking, GaMD Simulations, Correlation Network Analysis and MM-GBSA Calculations by Jianzhong Chen, Jian Wang, Wanchun Yang, Lu Zhao, Xiaoyan Xu

“…To this end, we employed Gaussian accelerated molecular dynamics (GaMD) simulations to enhance the sampling of 3CL^pro conformations and conducted correlation network analysis (CNA) to explore the interactions between different structural domains. …”
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Evaluation of three mechanisms of action (SGLT2 inhibitors, GLP-1 receptor agonists, and sulfonylureas) in treating type 2 diabetes with heart failure: a systematic review and netw... by Huize Gao, Qian Wei, Anqi Zou, Keying Yu, Da Song, Jian Li, Huize Han, Aidong Liu

“…A network meta-analysis was conducted to integrate available evidence and compare all interventions simultaneously.MethodsA comprehensive literature search was performed in PubMed, EMBASE, and the Cochrane Library. encompassing all available records up to December 10, 2024. …”
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Circ_MDM2_000139, Circ_ATF2_001418, Circ_CDC25C_002079, and Circ_BIRC6_001271 Are Involved in the Functions of XAV939 in Non-Small Cell Lung Cancer by Haixiang Yu, Lei Xu, Zhengjia Liu, Bo Guo, Zhifeng Han, Hua Xin

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Aconiti Lateralis Radix Praeparata ameliorates heart failure via PI3K/AKT/Bnip3 pathway by Wenxiu Liu, Xingju Zou, Yang Zheng, Yuan Zhang, Guijuan Cui, Siyu Liu, Chen Sun, Cheng Peng

“…The echocardiography was performed to investigate cardiac function. Histopathological analysis of cardiac tissue was conducted to assess myocardial fibrosis. …”
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Acupuncture for migraine: a literature review of neuroimaging studies by Dan Tong, Dan Tong, Dan Tong, Rui Yao, Rui Yao, Xinyue Zhang, Xinyue Zhang, Siyuan Tao, Siyuan Tao, Nuo Chen, Nuo Chen, Wanxia Wu, Wanxia Wu, Sai Wu, Sai Wu, Jun Zhou, Jun Zhou, Yulan Ren, Fanrong Liang, Fanrong Liang, Litao Pan, Zhengjie Li, Zhengjie Li, Zhengjie Li, Zhengjie Li

“…The immediate effects of acupuncture treatment for migraines primarily involve brain regions such as the middle frontal gyrus (MFG), precuneus, and postcentral gyrus, most of which belong to the default mode network (DMN), central executive network (CEN), and salience network (SN). …”
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Exploiting <i>Brassica rapa</i> L. subsp. <i>pekinensis</i> Genome Research by Faujiah Nurhasanah Ritonga, Zeyu Gong, Yihui Zhang, Fengde Wang, Jianwei Gao, Cheng Li, Jingjuan Li

“…However, challenges exist in integrating multi-omics for the functional analysis of genes and for developing potential traits for Chinese cabbage improvement. …”
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