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Shared pyroptosis pathways and crosstalk genes underpin inflammatory links between periodontitis and atherosclerosis
Published 2025-03-01“…Following batch effect correction and normalization, differential expression analysis was conducted using the limma package in R. Functional enrichment analysis was performed with the clusterProfiler package to identify key pathways, while heatmaps and pathway networks were constructed to visualize the relationships among pyroptosis genes and crosstalk genes. …”
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943
Microstructure-Driven Hygrothermal Behavior of Mycelium-Based Composites for Bio-Based Insulation
Published 2025-05-01“…The distinction between total and effective porosity emerged as a key factor in explaining discrepancies between apparent and functional moisture behavior. These findings demonstrate that hygric and thermal properties in MBCs are governed not by porosity alone, but by the geometry and connectivity of the internal fungal network. …”
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944
Network Pharmacology and In Vitro Experimental Validation Reveal the Anti-Inflammatory and Anti-Apoptotic Effects of Lotus Leaf Extract in Treating Inflammatory Diarrhea in Pigs
Published 2025-04-01“…Gene Ontology (GO) functional annotation and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis were conducted based on the genes shared between disease and LLE targets. …”
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945
The bridge between anxiety and insomnia symptoms among Chinese adults before and after SARS-CoV-2 vaccination: a network analysis
Published 2025-07-01“…Furthermore, a network comparison test was performed to compare network characteristics before and after vaccination.ResultsOur work showed that participants’ anxiety and insomnia scores were lower after vaccination than before vaccination. …”
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Evaluating core stability training-based combination therapies for lower extremity dysfunction post-stroke: a systematic review and network meta-analysis
Published 2025-07-01“…We searched six databases, including PubMed, Embase, Cochrane Library, Web of Science, CNKI (China National Knowledge Infrastructure), and SinoMed (China Biology Medicine), and conducted a network meta-analysis using R studio and Stata 15.0. …”
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948
Machine learning based multi-stage intrusion detection system and feature selection ensemble security in cloud assisted vehicular ad hoc networks
Published 2025-07-01“…This research ensures next-generation transport networks’ secure and reliable functioning and prepares the path for VANET protection upgrades. …”
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949
Development of an Algorithm for a National Microprocessor-Based Centralization System With a Modular Architecture KZ-MPC-MA Featuring Advanced Intelligent Control Functions
Published 2024-01-01“…The authors also present the architecture and key features of the developing microprocessor-based system. As a result of the conducted research, not only a prototype of the national microprocessor-based interlocking system KZ-MPC-MA, designed for controlling switches and signals at railway stations, was developed, furthermore ñomprehensive indicators of the functional safety of this system are defined to demonstrate compliance with the SIL4 according to CENELEC (European Committee for Electrotechnical Standardization) and TR/CU (Technical regulations in force within the Customs Union) requirements.…”
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950
Mind–body training outperforms other physical activities in reducing frailty and enhancing quality of life in older adults: a network meta-analysis
Published 2025-07-01“…However, the relative effectiveness of different types of physical activity modalities in mitigating frailty and enhancing activities of daily living (ADLs) and quality of life (QoL) remains insufficiently explored. This network meta-analysis quantified and compared the effects of different physical activities on frailty, ADLs, and QoL, providing an evidence base for targeted interventions.MethodsFollowing the PRISMA-NMA guidelines, we conducted systematic searches of PubMed, Embase, and CNKI to identify 35 randomized controlled trials (N = 2,905) between January 2000 and August 2024. …”
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951
InsNet-CRAFTY v1.0: integrating institutional network dynamics powered by large language models with land use change simulation
Published 2025-08-01“…We present InsNet-CRAFTY (Institutional Network – Competition for Resources between Agent Functional Types) v1.0, a multi-LLM-agent model with a polycentric institutional framework coupled with an agent-based land system model. …”
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952
RFCS-YOLO: Target Detection Algorithm in Adverse Weather Conditions via Receptive Field Enhancement and Cross-Scale Fusion
Published 2025-02-01“…It reconfigures the backbone network. This helps to make the receptive field better and improves its ability to extract features of targets at different scales. …”
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Remodeling characteristics of H3K27me3-marked silencers in gastric signet-ring cell carcinoma and its transcriptional regulatory function
Published 2025-03-01“…A regulatory network was constructed using Cytoscape, and then validated using immunohistochemistry to explore its regulatory mechanism. …”
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955
Efficacy and potential pharmacological mechanism of Astragalus-Salvia miltiorrhiza combination in diabetic nephropathy: integrating meta-analysis, network pharmacology, molecular d...
Published 2025-12-01“…The Astragalus and Salvia miltiorrhiza couplet medicines (AS) are commonly employed in DN clinical treatment in China, but their clinical efficacy and potential pharmacological mechanisms are yet to be evaluated.Material and Methods A meta-analysis of 15 studies involving 1,443 patients was conducted. Furthermore, network pharmacology predicted components and targets, which were verified by molecular docking and in vivo validation.Results In our meta-analysis, AS notably elevated clinical outcomes and renal function among patients with DN. …”
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956
Immune regulation and clinical response of Chinese herbal injections combined with TACE in hepatocellular carcinoma: a cumulative logit regression and Bayesian network meta-analysi...
Published 2025-04-01“…Cumulative logit regression and Bayesian network meta-analysis were applied to synthesize ordinal and continuous outcomes.ResultsCompared to TACE alone, Aidi, Compound Kushen, and Huachansu significantly enhanced the immune function. …”
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Optimization of electrical stimulation for the treatment of lower limb dysfunction after stroke: A systematic review and Bayesian network meta-analysis of randomized controlled tri...
Published 2023-01-01“…Pairwise meta-analysis and Bayesian network meta-analysis were conducted to estimate the effectiveness and ranking of the five electrical stimulation methods.…”
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958
A hybrid model for short-term offshore wind power prediction combining Kepler optimization algorithm with variational mode decomposition and stochastic configuration networks
Published 2025-07-01“…Finally, a multi-seasonal and multi-scenario wind power forecasting analysis is conducted by using an actual data set from an offshore wind farm in China. …”
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Mapping integral cell-type-specific interferon-induced gene regulatory networks (GRNs) involved in systemic lupus erythematosus using systems and computational analysis
Published 2025-01-01“…Furthermore, the derived differentially expressed genes were curated based on immune functions using functional enrichment analysis to create a protein-protein interaction network. …”
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960
Exploring Y1 Communications and Services in O-RAN: Background, Privacy, and Security
Published 2025-01-01“…In the latest open radio access network (O-RAN) architecture, the Y1 interface has been introduced to grant authorized parties, known as Y1 consumers, access to and utilization of Y1 data within the near-real-time RAN intelligent controller (Near-RT RIC). …”
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