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701
Programmed cell death signatures-driven microglial transformation in Alzheimer’s disease: single-cell transcriptomics and functional validation
Published 2025-07-01“…Weighted Gene Co-expression Network Analysis (WGCNA) was utilized to identify PCD-related genes. …”
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702
Phyllosphere Bacterial Communities in Wheat and Faba Bean Intercropping: Structural and Functional Mechanisms in Response to Stripe Rust Infection
Published 2025-06-01“…Pot experiments were conducted to investigate how wheat stripe rust, caused by Puccinia striiformis f. sp. tritici (Pst), affects shoot biomass, total nitrogen, and total potassium content; changes of phyllosphere bacteria; co-occurrence networks; and ecological functions in wheat and faba bean intercropping using 16S amplicon sequencing. …”
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703
Large-Scale Internetwork Functional Connectivity Mediates the Relationship between Serum Triglyceride and Working Memory in Young Adulthood
Published 2020-01-01“…In this study, 157 healthy young adults underwent resting-state functional MRI scans. Functional connectivity between and within 14 functional networks were calculated using independent component analysis. …”
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704
Multi-omics dissection of CPNE1 reveals its prognostic value and immune-regulatory function in liver cancer
Published 2025-08-01“…Subsequently, functional enrichment analysis was conducted to explore the related functions and signaling pathways of the target genes. …”
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705
Integrated bioinformatics and functional studies identify CDK9 as a potential prognostic biomarker and therapeutic target in AML
Published 2025-06-01“…Furthermore, the relationship between CDK9 expression and tumor immune infiltration was evaluated, and a protein–protein interaction (PPI) network was constructed. In vitro experiments, including Western blotting, CCK-8 assays, and flow cytometry, were conducted to validate the bioinformatics findings. …”
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706
Natural ligand 3,3’-diindolylmethane functions as an AHR agonist to modulate angiogenesis and organ development in chicken embryos
Published 2025-09-01“…Aryl hydrocarbon receptor (AHR) is a ligand-dependent transcription factor that is crucial for regulating various toxicological responses and physiological functions. Recent studies have highlighted that interactions between AHR and certain natural ligands can modulate inflammation and immune responses, offering therapeutic potential for a wide range of diseases. …”
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707
Modeling visual working memory using recurrent on-center off-surround neural network with distance dependent inhibition
Published 2025-07-01“…The model emphasizes the prioritization of object-related information before feature-related processing, effectively reversing the conventional feedforward order in visual perception. We conduct a detailed stability analysis to demonstrate non-divergence through energy function evaluations, highlighting the robustness of the network under varying input conditions. …”
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708
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709
An optimized potential formula of the $ m \times n $ apple surface network and its application of potential in path planning
Published 2025-03-01“…Based on the optimized potential function, we proposed a metaheuristic algorithm suitable for apple surface environment path planning. …”
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710
Respiratory rehabilitation techniques for patients with cystic fibrosis: a protocol for a systematic review and network meta-analysis
Published 2024-12-01“…This study intends to conduct a network meta-analysis to comprehensively evaluate and compare the effectiveness of different respiratory rehabilitation techniques in CF patients.Methods and analysis The following key electronic bibliographic databases will be searched from inception to September 2024: Medline, Embase, Cochrane Library, Web of Science, CINAHL and Physiotherapy Evidence Database. …”
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711
Warfarin use and vestibular dysfunction insights from NHANES data, network pharmacology, Mendelian randomization, and molecular docking
Published 2025-04-01“…However, its potential impact on vestibular function remains unexplored. This study investigates the association between warfarin use and vestibular dysfunction using data from the NHANES database and examines underlying mechanisms through network pharmacology, Mendelian randomization (MR), and molecular docking. …”
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712
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713
A physics-informed neural network-based method for predicting degradation trajectories and remaining useful life of supercapacitors
Published 2025-06-01“…Physical equations are embedded into the loss function to ensure consistency with domain knowledge, allowing the loss function to incorporate both physical and data-driven components. …”
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714
A novel interpreted deep network for Alzheimer’s disease prediction based on inverted self attention and vision transformer
Published 2025-08-01“…The fused features are finally classified using a shallow wide neural network and other classifiers. The experimental process was conducted on an augmented MRI dataset, and 96.1% accuracy and 96.05% precision rate were obtained. …”
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716
Comparative safety and efficacy of manual therapy interventions for cervicogenic headache: a systematic review and network meta-analysis
Published 2025-05-01“…ObjectiveTo evaluate and compare the safety and efficacy of spinal manipulation, mobilization, and massage for the management of cervicogenic headache (CGH) using meta-analytic techniques.MethodsComprehensive searches were conducted in Cochrane, Embase, PubMed, and ClinicalTrials.gov to identify studies investigating the effects of manipulation, mobilization, and massage on pain, disability, and physical function in patients with CGH. …”
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717
Optimal sigmoid function models for analysis of transspinal evoked potential recruitment curves recorded from different muscles.
Published 2025-01-01“…A Bland-Altman analysis was conducted to evaluate the agreement between the predicted parameters from the best models. …”
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718
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719
Abnormalities in cognitive-related functional connectivity can be used to identify patients with schizophrenia and individuals in clinical high-risk
Published 2025-03-01“…Methods Thirty drug-naive FSZ, 28 CHR, and 30 healthy controls (HCs) were recruited to undergo resting-state functional magnetic resonance imaging (rs-fMRI). Connectome-based predictive modeling (CPM) was employed to extract cognitive-related brain regions, which were then selected as seeds to form FC networks. …”
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720
Transposon-sequencing across multiple Mycobacterium abscessus isolates reveals significant functional genomic diversity among strains
Published 2025-02-01“…To determine the functional genomic diversity among Mab strains, we conducted transposon-sequencing (TnSeq) on 21 genetically diverse clinical isolates, including 15 M. abscessus subsp. abscessus isolates and 6 M. abscessus subsp. massiliense isolates, cataloging all the essential and non-essential genes in each strain. …”
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