Generative AI’s healthcare professional role creep: a cross-sectional evaluation of publicly accessible, customised health-related GPTs by Bianca Chu, Natansh D. Modi, Bradley D. Menz, Stephen Bacchi, Ganessan Kichenadasse, Ganessan Kichenadasse, Catherine Paterson, Catherine Paterson, Catherine Paterson, Joshua G. Kovoor, Joshua G. Kovoor, Joshua G. Kovoor, Imogen Ramsey, Jessica M. Logan, Michael D. Wiese, Ross A. McKinnon, Andrew Rowland, Michael J. Sorich, Ashley M. Hopkins

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Disturbed hierarchy and mediation in reward-related circuits in depression by Ruikun Yang, Junxia Chen, Suping Yue, Yue Yu, Jiamin Fan, Yuling Luo, Hui He, Mingjun Duan, Sisi Jiang, Dezhong Yao, Cheng Luo

“…Utilizing existing DBS targets as seeds, we conducted step-wise functional connectivity (sFC) analyses to delineate hierarchical pathways linking to cerebral cortices. …”
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Novel oxidative stress- and ferroptosis-related gene prognostic signature for erectile dysfunction by Meijun Liu, Maobin Yu, ZiYang Ma, Zilong Xu, Tao Zhang, Hongsen Zeng, Ze Li, XiYu Dang, Peihai Zhang

“…Enrichment analyses of these candidate target genes were conducted using ClusterProfiler, and the key chemically active ingredient-candidate target gene-KEGG pathway network was constructed using Cytoscape. …”
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A novel stemness-related lncRNA signature predicts prognosis, immune infiltration and drug sensitivity of clear cell renal cell carcinoma by Jia Liu, Lin Yao, Yong Yang, Jinchao Ma, Ruijian You, Ziyi Yu, Peng Du

“…Enrichment analysis was performed to explore the potential functions of SRmRNAs. Multiple machine learning algorithms were employed to construct a prognostic signature. …”
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Development and Validation of a Brain Aging Biomarker in Middle-Aged and Older Adults: Deep Learning Approach by Zihan Li, Jun Li, Jiahui Li, Mengying Wang, Andi Xu, Yushu Huang, Qi Yu, Lingzhi Zhang, Yingjun Li, Zilin Li, Xifeng Wu, Jiajun Bu, Wenyuan Li

“…We proposed a novel brain vision graph neural network (BVGN), incorporating neurobiologically informed feature extraction modules and global association mechanisms to provide a sensitive deep learning–based imaging biomarker. …”
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Contingent Analysis of Open Flap Debridement, Leukocyte-Rich Platelet-Rich Fibrin and Titanium Platelet-Rich Fibrin in the Treatment of Three-Walled Intra-Bony Defects in Chronic P... by Gowri Pendyala, Ameet Mani, Vinay Vadvadgi, Esha Thakare, Bharti Gupta

“…To overcome these limitations, the third generation of platelet concentrate Titanium PRF was introduced by Tunali et al 2013 by using biocompatible material titanium, where the fibrin network has a longer absorption time, increased capacity for osseointegration, better hemocompatibility, greater cellular support, and it promotes periodontal regeneration. …”
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Identification of early Alzheimer’s disease subclass and signature genes based on PANoptosis genes by Wenxu Wang, Wenxu Wang, Jincheng Lu, Jincheng Lu, Ningyun Pan, Ningyun Pan, Huiying Zhang, Jingcen Dai, Jie Li, Cheng Chi, Liumei Zhang, Liang Wang, Mengying Zhang, Mengying Zhang

“…Consensus clustering analysis was conducted to define AD subtypes based on these genes. …”
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Profiling of the serum MiRNAome in pediatric egyptian patients with wilms tumor by Fatma S. Mohamed, Fatma S. Mohamed, Deena Jalal, Youssef M. Fadel, Samir F. El-Mashtoly, Wael Z. Khaled, Wael Z. Khaled, Ahmed A. Sayed, Ahmed A. Sayed, Mohamed A. Ghazy, Mohamed A. Ghazy

“…The study used next-generation sequencing (NGS) to analyze miRNA expressions in serum samples from 37 Egyptian children, including 10 healthy individuals, 14 with non-anaplastic WTs (favorable histology FH-WTs), and 13 with anaplastic WTs (unfavorable histology UnFH-WTs). Functional enrichment analysis was conducted to identify critical pathways and biological processes affected by dysregulated miRNAs, and a network was created for the most promising miRNA-target interactions linked to WT. …”
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Genome-Wide Identification and Expression Analysis of the Mango (<i>Mangifera indica</i> L.) SWEET Gene Family by Lirong Zhou, Xinyu Liu, Xiangchi Leng, Meng Zhang, Zhuanying Yang, Wentian Xu, Songbiao Wang, Hongxia Wu, Qingzhi Liang

“…A systematic predictive analysis was conducted on their physicochemical properties, homology relationships, phylogenetic relationships, chromosomal locations, genomic structures, promoter cis-acting elements, and transcription factor regulatory networks. …”
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The osteosarcoma immune microenvironment in progression: PLEK as a prognostic biomarker and therapeutic target by Yunpeng Zou, Yunpeng Zou, Jianning Kang, Shaopeng Zhu, Xuechen Ren, Zheng Li, Jiayao Niu, Xuanzhe Qin, Hongbo Li, Lu Xiang, Wei Jiang, Jiangbo Zhong, Ying Zhang, Ying Zhang, Kai Zhao

“…Protein–protein interaction networks, GO/KEGG enrichment, and CytoHubba algorithms identified core hub genes. …”
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“Dictionary of immune responses” reveals the critical role of monocytes and the core target IRF7 in intervertebral disc degeneration by Peichuan Xu, Peichuan Xu, Kaihui Li, Jinghong Yuan, Jinghong Yuan, Jiangminghao Zhao, Jiangminghao Zhao, Huajun Pan, Huajun Pan, Chongzhi Pan, Chongzhi Pan, Wei Xiong, Wei Xiong, Jianye Tan, Jianye Tan, Tao Li, Tao Li, Guanfeng Huang, Guanfeng Huang, Xiaolong Chen, Xiaolong Chen, Xinxin Miao, Dingwen He, Xigao Cheng, Xigao Cheng

“…Differential gene expression analysis, PPI network, GO and KEGG pathway enrichment analysis, GSVA, co-expressed gene analysis and key gene-related networks were also performed to explore hub genes and their associated functions. …”
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Single-stage surgery with antibiotic-loaded hydrogel-coated implants versus two-stage surgery for chronic periprosthetic hip joint infection in French tertiary referral hospitals:... by Elisabeth Botelho-Nevers, Emilie Presles, Anne Carricajo, Céline Chapelle, Bertrand Boyer, Celine Cazorla, Carine Labruyere, Paul Zufferey

“…The single-stage procedure is thought to be less susceptible to late functional complications with a shorter, single hospital stay. …”
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Juanbi Qianggu Formula inhibits fibroblast-like synovicytes activation via repressing LncRNA ITSN1-2 to promote RIP2 K48 ubiquitination by Yanqin Bian, Fang Li, Xinyu A, Zheng Xiang, Nanshan Ma, Jianye Wang, Boran Cao, Pengfei Xin, Xuan Cheng, Chang Liu, Bei Xiang, Jun Shen, Qigui Lu, Lianbo Xiao

“…Blood-absorbed components of JBQG were analyzed through mass spectrometry, while network pharmacology and in vitro experiments were conducted to investigate JBQG's regulatory effects on NOD2/RIP2 signaling. …”
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Case Report: Compound heterozygous variants in BHLHA9 cause complex syndactyly with oligodactyly, renal artery variation, and facial scar by Weidong Wei, Weidong Wei, Xiaosha Wang, Xiaosha Wang, Tao Zhang, Tao Zhang, Yongxing Zhong, Yongxing Zhong, Jintang Zhang, Jintang Zhang, Hua Yuan, Hua Yuan, Xiaoliang Shi, Xiaoliang Shi, Yao He, Yao He, Haitao Pan, Haitao Pan, Zhen Yang, Yuejuan Wang

“…Evolutionary conservation analysis and structural predictions using AlphaFold were conducted to assess the functional impact of the variants. …”
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On Channel Transforms to Enhance Reciprocity and Quantization in Physical-Layer Secret Key Generation by Ghalib Hussain, Syed Junaid Nawaz, Shurjeel Wyne, Mohammad N. Patwary

“…Furthermore, for the considered system and channel parameters the proposed algorithm provides an average improvement of 0.06% in KDR compared to cumulative distribution function (CDF)-based non-uniform quantization (CDF-NUQ).…”
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The state of public health emergency preparedness and response capacity among countries in the ECOWAS region by Mahmood Dalhat, Margaret Yaa Lartey

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The impact of aztreonam–clavulanic acid exposure on gene expression and mutant selection using a multidrug-resistant E. coli by Tongtong Lin, Jiayuan Zhang, Shuo Diao, Jinke Yan, Kexin Zhang, Jichao Cao, Junyi Huang, Yaohai Wang, Zhihua Lv, Xiaopeng Shen, Sherwin K. B. Sy, Michael Lynch, Hongan Long, Mingming Yu

“…Differential gene expression, pathway enrichment, and gene network analyses demonstrated the polygenic nature of the response to the combination treatment, which suppressed the expression of pivotal virulence genes, disrupted two-component regulatory systems for bacteria to resist external stress, and interfered with the formation of the cellular membrane. …”
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Exploring the role of ferroptosis in pemphigus: identification of diagnostic markers and regulatory mechanisms by Jing Mao, Jianping Lan, Zheyu Zhuang, Ying Chen, Ying Chen, Yushan Ou, Xinhong Su, Xueting Zeng, Fuchen Huang, Zequn Tong, Xiaoqing Lv, Xiaoqing Lv, Xiaoqing Lv, Hui Ke, Zhenlan Wu, Ying Zou, Bo Cheng, Bo Cheng, Bo Cheng, Chao Ji, Chao Ji, Chao Ji, Ting Gong

“…Weighted Gene Co-expression Network Analysis (WGCNA) was employed to identify co-expressed gene modules related to pemphigus. …”
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A pan-cancer analysis of the prognostic and immunological roles of zinc finger protein 514 in human tumors by Shuai Zhao, Shuai Zhao, Shuai Zhao, Lin Cheng, Xingzhao Ji, Xingzhao Ji, Shengnan Sun, Shengnan Sun, Shengnan Sun, Yi Liu, Yi Liu, Qiang Wan, Qiang Wan, Qiang Wan

“…Furthermore, we conducted cellular functional experiments to examine the effects of ZNF514 overexpression or knockdown on renal clear cell carcinoma cell proliferation, migration, and invasion.ResultsOur study found that ZNF514 expression was elevated in tumor tissues than in normal tissues in most tumor types. …”
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Soil moisture product consistency for operational drought monitoring in Europe by J. Gaona, D. Bavera, G. Fioravanti, S. Hahn, P. Stradiotti, P. Filippucci, S. Camici, L. Ciabatta, H. Mosaffa, S. Puca, N. Roberto, L. Brocca

“…The merging of the products is conducted by combining the various products based on weights calculated proportionally to the R_TCA scores of the triplets equalized in dynamic range matching their cumulative distribution functions. …”
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