Designing a Digital Intervention to Increase Human Milk Feeding Among Black Mothers: Qualitative Study of Acceptability and Preferences by Loral Patchen, Jeannette Tsuei, Donna Sherard, Patricia Moriarty, Zoe Mungai-Barris, Tony Ma, Elina Bajracharya, Katie Chang, William Douglas Evans

“…Third, functionality and features were identified as key factors, highlighting content diversity, ease of use, credibility, and interactivity. …”
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Effect of the S100A9/AMPK pathway on PM2.5-mediated mouse lung injury by Yunxia Li, Yunxin Bai, Shiyu Tang, Ye Sun, Zhe Wang, Biao Yang, Guangyan Liu

“…Objective(s): Particulate matter 2.5 (PM2.5), particles with an aerodynamic diameter less than 2.5 µm, affect lung function and increase respiratory disease incidence and mortality rate. …”
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GINS1 is a prognostic biomarker and correlated with methylation and immune escape in liver hepatocellular carcinoma by Mingchao Liang, Tianqi Lai, Tianqi Lai, Zhen Li, Wei Yu, Mingrong Cao, Nan Yao, Youzhu Hu, Youzhu Hu, Tongzheng Liu, Junjie Liang

“…GeneMANIA and STRING databases were respectively used to construct gene and protein-protein interaction (PPI) networks of GINS1. Enrichment analyses were conducted to investigate the functions of GINS1. …”
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Single-cell RNA sequencing reveals the heterogeneity and regulatory modules of cell-specific RNA-binding proteins in patients with systemic lupus erythematosus by Sheng-Yan Lin, Yikai Yu, Daan Nie, Lili Yang, Yuxue Chen, Yu Chen, Cheng Wen, Zhipeng Zeng

“…Cross-analysis with bulk transcriptomic data highlighted JUN and HLA-A as hub regulators exhibiting elevated expression in SLE T cells. Network modeling further uncovered coordinated interactions between JUN, HLA-A, and RAS events in immune genes, implicating their synergistic roles in modulating T cell effector functions. …”
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TIMM8B promotes oxidative phosphorylation and glycolysis by inhibiting the mtROS/ASK1/JNK signaling pathway in ovarian cancer by Yue Jia, Jiaqian Liao, Xiangqun Yang, Hongyan Hu, Wentao Zhao, Liufang Zhao, Conghui Ai, Yuanbo Xue, Shufen Tan, Yi Zhang

“…GO, KEGG pathway, and PPI network analyses of these common DEGs were conducted. …”
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Construction of a Wilms tumor risk model based on machine learning and identification of cuproptosis-related clusters by Jingru Huang, Yong Li, Xiaotan Pan, Jixiu Wei, Qiongqian Xu, Yin Zheng, Peng Chen, Jiabo Chen

“…This involved analyzing associated immune cell infiltration and conducting functional enrichment analysis. Disease-characteristic genes were pinpointed using weighted gene co-expression network analysis. …”
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Formation of biocenoses in roadside landscapes of Cherkasy Region by Ірина Кравцова, Сергій Сонько, Ольга Василенко, Ігор Гурський, Станіслав Огілько

“…The problem solved in the article is relevant primarily due to the constant growth of the density of the transport network, and, therefore, the ever-increasing "theft" of natural ecosystems by humans from aboriginal plants and animals. …”
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Single-Cell Sequencing Combined with Transcriptome Sequencing to Explore the Molecular Mechanisms Related to Skin Photoaging by Hu X, Du S, Chen M, Yang H, He J, Zhang L, Tan B, Wu T, Duan X

“…Finally, merging gene co-expression networks with drug prediction shows molecular pathways of photoaging and potential treatment targets. …”
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Comparative assessment of machine learning algorithms for retrieving colored dissolved organic matter (CDOM) from Sentinel-2/MSI images in the coastal waters of the Persian Gulf by Bonyad Ahmadi, Mehdi Gholamalifard, Seyed Mahmoud Ghasempouri, Tiit Kutser

“…Machine learning models further enhanced retrievals, with the Mixture Density Network (MDN) emerging as the superior framework. …”
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Single-cell technology reveals the crosstalk between tumor cells and immune cells: driving immune signal transduction and inflammation-mediated cardiac dysfunction in the tumor mic... by Wenyang Nie, Wangzheqi Zhang, Zhikai Xiahou, Yuxuan Meng, Yuhang Liu, Jingwen Zhang, Zhen Wang, Yong Wang

“…Prognostic modeling was conducted using Cox regression and LASSO. Immune infiltration and drug sensitivity were evaluated by CIBERSORT, ESTIMATE, xCell, TIDE, and pRRophetic. …”
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Target oxidative stress-induced disulfidptosis: novel therapeutic avenues in Parkinson’s disease by Junshi Zhang, Tingting Liu, Haojie Wu, Jianshe Wei, Qiumin Qu

“…These datasets were subjected to: immune infiltration analysis, gene set enrichment analysis (GSEA), weighted gene co-expression network analysis (WGCNA), intersection analysis of oxidative stress-related genes (ORGs) and disulfidptosis-related genes (DRGs) for functional enrichment annotation. …”
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An FPGA-Based SiNW-FET Biosensing System for Real-Time Viral Detection: Hardware Amplification and 1D CNN for Adaptive Noise Reduction by Ahmed Hadded, Mossaad Ben Ayed, Shaya A. Alshaya

“…Notably, the findings presented in this work are based exclusively on comprehensive simulations using COMSOL and MATLAB, as no physical prototypes or biomarker detection experiments were conducted. The SiNW-FET biosensor, functionalized with antibodies specific to viral antigens, detects impedance shifts caused by antibody–antigen interactions, providing a highly sensitive platform for viral detection. …”
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Single-cell sequencing-based study of ferroptosis mechanisms in heat stroke: identification of key biomarkers and dynamic analysis of the immune microenvironment by Defeng Yin, Qin Guo, Hao Jiang, Yonglan Hu, Lu Liu, Xiang Li, Chenglin Wang, Shilin Li, Kaiyu Jin, Yingchun Hu

“…Methods Peripheral blood samples from 29 heat stroke patients, recruited at an early stage of the condition, underwent transcriptome sequencing, and single-cell RNA sequencing was conducted for two representative cases. Ferroptosis-related genes were identified by integrating the FerrDB database, followed by weighted gene co-expression network analysis (WGCNA) and differential gene expression analysis to pinpoint ferroptosis-related genes most characteristic of heat stroke. …”
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Autonomous International Classification of Diseases Coding Using Pretrained Language Models and Advanced Prompt Learning Techniques: Evaluation of an Automated Analysis System Usin... by Yan Zhuang, Junyan Zhang, Xiuxing Li, Chao Liu, Yue Yu, Wei Dong, Kunlun He

“…Its performance was compared against robustly optimized BERT pretraining approach, extreme language network, and various BERT-based fine-tuning pipelines. …”
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SPECC1 as a pan-cancer biomarker: unraveling its role in drug sensitivity and resistance mechanisms by Dongwei Liu, Xidi Wang, Lingfei Cui, Mingxia Zhang, Kefeng Lei, Nijiati Aierken

“…Abstract Previous studies have shown a relationship between SPECC1 and the prognosis of breast cancer, indicating a potential function for SPECC1 in the initiation and progression of cancer. …”
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Multi-omic integration of single-cell data uncovers methylation profiles of super-enhancers in skeletal muscle stem cells by Anyu Zeng, Hailong Liu, Shuling He, Xuming Luo, Zhiqi Zhang, Ming Fu, Baoxi Yu

“…The target genes and motifs were analyzed using KEGG, GO, and HOMER to identify key biological pathways and functions, followed by validation through snATAC-seq and immunofluorescence techniques. …”
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The glycosaminoglycan chains of perlecan regulate the perivascular fluid transport by Abhishek Singh, Mika Kaakinen, Harri Elamaa, Vesa Kiviniemi, Lauri Eklund

“…Abstract Background The perivascular conduct pathway that connects the cerebrospinal fluid spaces with the interstitial fluid in the parenchyma are of importance for solute clearance from the brain. …”
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The bioinformatics analysis and experimental validation of the carcinogenic role of EXO1 in lung adenocarcinoma by Bohao Sun, Jing Zhang, Nan Wang, Zhirong Zhang, Yichen Wu, Mengzhen Xie, Yanmei Peng, Yifan Ye, Zhaochang Jiang, Shumei Wei

“…Immunohistochemistry was utilized to assess EXO1 expression in 93 cases of invasive pulmonary adenocarcinoma. Finally, cellular functional assays were conducted to investigate the impact of EXO1 on LUAD cells.ResultsTen key molecules (PBK, ASPM, NCAPG, EXO1, MKI67, RRM2, AURKA, DLGAP5, UBE2C, and CDC6) exhibited significantly elevated expression levels in LUAD tissues. …”
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ORGANIZING THE WORK OF THE DONOR BREAST MILK BANK AT THE LVIV PERINATAL CENTER IS AN EXPERIENCE THAT MOTIVATES FURTHER DEVELOPMENT by М. Малачинська, М. Кісельова, О. Шлемкевич, Н. Вереснюк, Г. Коваленко

“…Errors in feeding breastfed infants negatively affect not only the child’s physical health but also their functional capacities. No substitute for human milk can compete with the presence of biologically active substances inherent to the mother-child symbiosis. …”
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S100A9 as a promising therapeutic target for diabetic foot ulcers by Renhui Wan, Shuo Fang, Xingxing Zhang, Weiyi Zhou, Xiaoyan Bi, Le Yuan, Qian Lv, Yan Song, Wei Tang, Yongquan Shi, Tuo Li, Sihan Zhou, Xiuyuan Hao

“…Enrichment analysis was conducted to screen for critical gene functions and pathways. …”
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