Bioinformatics-driven exploration of key genes and mechanisms underlying oxidative stress in traumatic brain injury by Bin Ren, Jifang Liang, Leifang Yang, Xiaocong Wei, Min Guo, Hong Li

“…Immune infiltration analysis and regulatory network construction were conducted. Molecular validation included RT-qPCR and Western blotting using rat brain tissue to assess gene and protein expression levels.ResultsIn our study, we identified 400 differentially expressed genes (DEGs) between TBI and normal samples, including 20 oxidative stress-related genes. …”
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The molecular mechanism and utilization of ZmMs7-mediated dominant nuclear sterility in Oryza sativa L by Yusheng Xu, Yusheng Xu, Dingyang Yuan, Meijuan Duan

“…This study provides new insights into the molecular regulatory network governing male reproductive development in rice and offers a theoretical foundation and technical support for the development of novel male-sterile germplasm resources.…”
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Toward precision oncology in LUAD: a prognostic model using single-cell sequencing and WGCNA based on a disulfidptosis relative gene signature by Panpan Li, Han Zhang, Limin Sun, Xiaojuan Wu

“…In the TCGA [LUAD] dataset, disulfidptosis-related enrichment scores were calculated using ssGSEA, and core gene sets were identified through the Weighted Gene Co-expression Network Analysis (WGCNA) algorithm. Differential gene analysis was conducted using the limma package and intersected with core gene sets. …”
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Identification and Validation of Serum Biomarkers to Improve Colorectal Cancer Diagnosis by Minha Lea Yoon, Hyelim Chun, HyunJu Lee, WooJeong Seo, Jung Young Lee, Jung Hwan Yoon

“…We identified differentially expressed genes (DEGs) and conducted further analyses, including Gene Ontology (GO) enrichment and Protein‐Protein Interaction (PPI) network construction. …”
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Study on the molecular mechanism of UBA52 and BARD1 regulating hepatocellular carcinoma through the PI3 K/AKT signaling pathway by Chenrui Yang, Yanzhong Zhang, Yajuan Liu, Xiaoyong Wu, Fangyuan Sun

“…Methods This study integrated HCC datasets (GSE135631, GSE184733, GSE202853) from the gene expression omnibus (GEO) database to screen for differentially expressed genes (DEGs), perform functional enrichment analysis, weighted gene co-expression network analysis (WGCNA), construct protein–protein interaction (PPI) networks, and conduct survival analysis. …”
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Integration analysis of cis- and trans-regulatory long non-coding RNAs associated with immune-related pathways in non-small cell lung cancer by Yinqiang Liu, Hongjv Yang, Guoli Lv, Jin Duan, Wei Zhao, Yunfei Shi, Youming Lei

“…Gene set enrichment analysis, Kyoto Encyclopedia of Genes and Genomes, and Gene Ontology were conducted to discern the biological functions of identified differentially expressed transcripts. …”
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MiR-485-3p/MELK cascade mediates tumor progression in pancreatic cancer by Yishan Huang, Ting Yang, Chen Yang, Bo Tang, Bo Su, Xiaojun Yang

“…The identification of differentially expressed genes (DEGs) and subsequent analyses, including signaling pathway enrichment, functional classification, and protein-protein interaction (PPI) network construction, were conducted using three public datasets: GSE32676, GSE71989, and GSE16515. …”
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Identification and validation of prognostic biomarkers in ccRCC: immune-stromal score and survival prediction by Fang Lyu, Yuxin Zhong, Qingliu He, Wen Xiao, Xiaoping Zhang

“…The weighted gene co-expression network analysis (WGCNA) was employed to identify gene modules associated with these scores. …”
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6G RIS in Indoor Environments: Assessment of Exposure Variability in Human Users and Non-Users by Silvia Gallucci, Martina Benini, Serena Fiocchi, Gabriella Tognola, Marta Parazzini

“…The aim of the present work is to assess the exposure of human users and non-users in indoor scenarios due to novel technology that will be integrated in 6G network in order to overcome the obstacles in NLOS area: Reconfigurable Intelligent Surface (RIS), here tuned in FR1-band. …”
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Comparative effectiveness of various orbital decompression techniques in treating thyroid-associated ophthalmopathy: a systematic review and meta-analysis by Wei Guo, Jialu Geng, Dongmei Li

“…Methods Systematic searches were conducted to identify pertinent studies from PubMed, Embase, and the Cochrane Library databases. …”
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A comprehensive analysis of molecular characteristics of hot and cold tumor of gastric cancer by Chenxi Lv, Tianwei Chen, Jiangtao Li, Yuqiang Shan, Hong Zhou

“…Immune “hot” tumor-related genes were identified, and their functional roles were validated through biological behavior analysis. …”
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Identification of key genes CCL5, PLG, LOX and C3 in clear cell renal cell carcinoma through integrated bioinformatics analysis by Zhenwei Xie, Cheng Feng, Yude Hong, Libo Chen, Mingyong Li, Weiming Deng

“…In this study, we identified several key genes associated with the prognosis of ccRCC by using integrated bioinformatics.MethodsTwo ccRCC expression profiles were downloaded from Gene Expression Omnibus and one dataset was gained from The Cancer Genome Atlas The Robust Rank Aggregation method was used to analyze the three datasets to gain integrated differentially expressed genes The Gene Ontology and KEGG analysis were performed to explore the potential functions of DEGs. The Search Tool for the Retreival of Interacting Genes/Proteins (STRING) and Cytoscape software were used to construct protein-protein interaction network and module analyses to screen the hub genes. …”
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Sciatic nerve injury treated by acupuncture: a bibliometric study and visualization analysis by Yan Wang, Yan Wang, Fei Pei, Yahui Wang, Lijie Lv, Tianyi Li, Shujin Wang, Huan Qin

“…Bibliometric and scientific knowledge mapping methods were employed to analyze the current research status, hotspots, and development trends of acupuncture for sciatic nerve injury (SNI) over the past decade.MethodsA literature search was conducted on acupuncture for SNI from the China Knowledge (CNKI), Wanfang, Weipu (VIP), and Web of Science (WOS) databases, and CiteSpace V6.R6 software and VOSviewer1.6.20 software were employed to analyze and visualize keywords from the collaborative network, keyword co-occurrence, and keyword timeline, respectively. …”
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Preliminary study of key specific genes involved in tubular ferroptosis in diabetic kidney disease by Ma Li-li, Jiang Lin, Fu Li, Wei Rui, Wang Ting-ting

“…ObjectiveTo explore the key genes of ferroptosis involved in renal tubulointerstitium of diabetic kidney disease （DKD） and its clinical relevance by bioinformatics analysis.MethodsDKD and non-DKD datasets of renal tubulointerstitial tissue were obtained to identify differentially expressed genes （DEGs）， and DKD-specific ferroptosis-related genes. Functional enrichment and protein-protein interaction network （PPI） analyses were conducted. …”
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The developmental transcriptome dynamics of current-year shoot utilized as scion in Camellia chekiangoleosa by Yu Sheng, Haili Gao, Chunlian Yu, Guangyuan Huang, Kunxi Wang, Kailiang Wang, Leyan Lv, Wei Long

“…Coexpression network analysis revealed that red/far-red light and gibberellin (GA) signaling were closely correlated with flowering development in C. chekiangoleosa shoots. …”
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Identification of Diagnostic Biomarkers and Therapeutic Targets in Sepsis-Associated ARDS via Combining Bioinformatics with Machine Learning Analysis by Liu T, Gao L, Li X

“…Weighted Gene Co-expression Network Analysis (WGCNA) was performed to explore gene co-expression modules. …”
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Educational trajectories of school graduates of the Russian industrial region by I. A. Aleshkovski, A. I. Moteva, N. E. Savina, A. T. Gasparishvili, O. V. Krukhmaleva

“…At the stage of data analysis in the SPSS 25 functional environment, primary data were processed and the results were presented using descriptive statistics methods; an in-depth analysis of empirical information was carried out using multidimensional methods of analytical statistics, including the Pearson’s χ2 significance test, the procedures of factor, correlation and regression analysis (p < 0.001).Research results and scientific novelty. …”
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Genome-wide identification of PP2A gene family in Camellia sinensis reveals the potential role of CsPP2A-TON2/FASS1 in abiotic stress by Surjit Bhattacharjee, Abhirup Paul, Aradhana Jana, G. Meher Unnati, Deepak R., Ye Miao, Honglin Lu, Guoxin Shen, Neelam Mishra

“…Conclusion This study offers potential goals for further in-depth investigation and functional analysis, alongside enhancing our understanding of the regulatory network of PP2A genes in C. sinensis.…”
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Identification of the prognostic effect of mitophagy-related genes in acute myeloid leukemia by Fan Xuan, Wenyuan Zhu, Baoxi Zhang, Hui Zhao, Chaonan Li, Xiaoli Wu

“…A prognostic risk model was constructed and validated. Functional enrichment, immune infiltration, and drug sensitivity analyses were conducted to explore the biological relevance of the model. …”
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Ionic‐electronic dual‐conductor interface engineering and architecture design in layered lithium‐rich manganese‐based oxides by Youyou Fang, Yuefeng Su, Jinyang Dong, Jiayu Zhao, Haoyu Wang, Ning Li, Yun Lu, Yujia Wu, Wenbo Li, Ni Yang, Xiaojuan Wu, Feng Wu, Lai Chen

“…Prolonged electrochemical and structural analyses demonstrate that this IEDC heterostructure effectively minimizes polarization, mitigates structural distortion, and enhances electronic/ionic diffusion. Density functional theory calculations highlight an extensive Li+ percolation network and lower Li+ migration energies at the layered‐spinel interface. …”
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