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Single-cell technology reveals the crosstalk between tumor cells and immune cells: driving immune signal transduction and inflammation-mediated cardiac dysfunction in the tumor mic...
Published 2025-08-01“…The cancer model utilizing the MKI67+ TCs subpopulation (MTRS) successfully classified patient survival and linked with immune infiltration patterns and medication responses. Enrichment analysis revealed tumor-promoting and immunological signaling networks. …”
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1842
Knowledge Mapping of COVID-19 and Asthma/Allergic Rhinitis: A Visual and Bibliometric Analysis
Published 2025-05-01“…Analysis tools such as VOSviewer and CiteSpace were employed to perform network mappings and citation analyses, focusing on co-authorship networks, keyword co-occurrences, and citation impacts to understand the research dynamics and collaborative patterns within this field.Results: A collection of 553 publications was obtained, revealing an upward trend in research volume over the study period. …”
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1843
A multi-module enhanced YOLOv8 framework for accurate AO classification of distal radius fractures: SCFAST-YOLO
Published 2025-08-01“…Third, our Feature-Driven Pyramid Network facilitates multi-resolution feature fusion across scales for improved detection. …”
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1844
Identification of novel metabolism-related biomarkers of Kawasaki disease by integrating single-cell RNA sequencing analysis and machine learning algorithms
Published 2025-04-01“…The cellular expression patterns of signature genes were further validated using our own scRNA-seq dataset. …”
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1845
Integrated pan-cancer analysis of ADM’s role in prognosis, immune modulation and resistance
Published 2025-06-01“…ADM’s correlations with immune checkpoint genes, immune cell infiltration, MSI, and TMB were evaluated using data from Timer and TCGA via R. Drug sensitivity analysis was performed with GDSC and CTRP databases, supported by network visualizations. …”
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1846
A Multimodal Pain Sentiment Analysis System Using Ensembled Deep Learning Approaches for IoT-Enabled Healthcare Framework
Published 2025-02-01“…The first phase focuses on detecting the facial region from a video sequence, a crucial step for extracting facial patterns indicative of pain. In the second phase, the system extracts discriminant and divergent features from the facial region using deep learning techniques, utilizing some convolutional neural network (CNN) architectures, which are further refined through transfer learning and fine-tuning of parameters, alongside fusion techniques aimed at optimizing the model’s performance. …”
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1847
Human immunodeficiency virus prevention and testing strategies among men who have sex with men in the UK: the PANTHEON research programme including the SELPHI RCT
Published 2024-10-01“…To develop and undertake a process evaluation to assess what worked well about the RCT intervention and for whom. …”
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1848
Three Circulating miRNAs Related to Non-Small-Cell Lung Cancer Progression: An Integrative Analysis of Their Biological Roles
Published 2025-04-01“…We then performed protein–protein interaction (PPI) analysis and constructed a miRNA-hub gene regulatory network based on targets predicted by several miRNA-target prediction tools. …”
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1849
The arrow of time in Parkinson’s disease
Published 2025-01-01“…Results: We found that PD is characterized by disrupted equilibrium regimes, marked by distinct effective connectivity patterns, particularly within the motor networks. Additionally, we observed a flatter hierarchical organization in PD, with the cerebellum and thalamus exerting increased influence. …”
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1850
Deterministic Light Detection and Ranging (LiDAR)-Based Obstacle Detection in Railways Using Data Fusion
Published 2025-03-01“…This real-world testing scenario allowed the evaluation of the framework’s effectiveness under realistic operating conditions. …”
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1851
Deep-Learning-Based Land Cover Mapping in Franciacorta Wine Growing Area
Published 2025-01-01“…Land cover mapping is essential to understanding global land-use patterns and studying biodiversity composition and the functioning of eco-systems. …”
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1852
Estimation of Ca2+ wet deposition in the Northern Hemisphere by use of CNN deep-learning model
Published 2025-07-01“…Our findings provide insights into Ca2+ wet deposition patterns and underline ecological importance, supporting future environmental management.…”
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1853
Bibliometric analysis of biochar application for environmental management in agricultural sector
Published 2024-11-01“…The retrieved data were analyzed using the Bibliometrix package in RStudio to evaluate publication trends, research theme evolution, and international collaboration networks. …”
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1854
Mapping Burned Area in the Caatinga Biome: Employing Deep Learning Techniques
Published 2024-11-01“…This research aims to evaluate the effectiveness of a fire detection model and analyze the spatial and temporal patterns of burned areas, providing essential insights for fire management and prevention strategies. …”
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1855
Generative AI in construction risk management: a bibliometric analysis of the associated benefits and risks
Published 2025-03-01“…Using VOSViewer, visual maps illustrate research trends, collaboration networks and citation patterns. Findings – The findings reveal a notable increase in research interest in GenAI for CRM, with benefits classified into technical, operational, technological and integration categories. …”
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1856
Identification of Isoflavonoid Biosynthesis-Related R2R3-MYB Transcription Factors in Callerya speciosa (Champ. ex Benth.) Schot Using Transcriptome-Based Gene Coexpression Analysi...
Published 2021-01-01“…Conserved motifs and domain distribution, expression patterns, and coexpression networks were also employed to identify the potential R2R3-MYB TFs in the regulation of isoflavonoid biosynthesis. …”
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1857
Weighted EHR-based prevalence estimates for hypertension at the state and local levels in Louisiana
Published 2025-02-01“…Demographic and geographic patterns in prevalence of hypertension control were like hypertension prevalence. …”
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1858
Multidimensional analysis suggests that ZNF433 is a promising biomarker for the diagnosis and prognosis of human cancers
Published 2025-06-01“…Functional enrichment and protein interaction network analyses were also performed to explore its potential involvement in cancer-related pathways.ResultsOur findings revealed that ZNF433 is significantly downregulated in most cancer types, with stage-dependent expression patterns observed in KIRC and KIRP. …”
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1859
Drug-induced second tumors: a disproportionality analysis of the FAERS database
Published 2025-05-01“…Additionally, the Weibull Shape Parameter (WSP) was used to analyze the characteristic patterns of time-to-onset curves. Newly discovered signals were verified against FDA drug labels to confirm their novelty. …”
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1860
A real-world disproportionality analysis of FDA adverse event reporting system (FAERS) events for lecanemab
Published 2025-04-01“…The median time to the occurrence of these AEs was 44 days after administration in AD patients and 30 days for Non-AD patients.ConclusionThis study utilized the FAERS database to evaluate lecanemab-associated AEs in AD and non-AD patients, along with their temporal patterns post-marketing authorization, thereby establishing a foundation for subsequent clinical pharmacovigilance. …”
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