Stage-specific modulation of Drosophila gene expression with muscle GAL4 promoters by Ziwei Zhao, Erika R Geisbrecht

“…The bipartite GAL4/UAS system is the most widely used method for targeted gene expression in Drosophila melanogaster and facilitates rapid in vivo genetic experimentation. …”
Get full text

Research Progress on Information Model of Urban Green Space by Wei ZHANG, Yahan YAN

“…Spatial geometric models are designed to express plants’ spatial geometric characteristics, including tree branching and leaf structures. …”
Get full text

Suppressing recurrence in Sonic Hedgehog subgroup medulloblastoma using the OLIG2 inhibitor CT-179 by Yuchen Li, Chaemin Lim, Taylor Dismuke, Daniel S. Malawsky, Sho Oasa, Zara C. Bruce, Carolin Offenhäuser, Ulrich Baumgartner, Rochelle C. J. D’Souza, Stacey L. Edwards, Juliet D. French, Lucy S. H. Ock, Sneha Nair, Haran Sivakumaran, Lachlan Harris, Andrey P. Tikunov, Duhyeong Hwang, Coral Del Mar Alicea Pauneto, Mellissa Maybury, Timothy Hassall, Brandon Wainwright, Santosh Kesari, Gregory Stein, Michael Piper, Terrance G. Johns, Marina Sokolsky-Papkov, Lars Terenius, Vladana Vukojević, Leon F. McSwain, Timothy R. Gershon, Bryan W. Day

“…Abstract OLIG2-expressing tumor stem cells have been shown to drive recurrence in Sonic Hedgehog (SHH)-subgroup medulloblastoma (MB) and patients urgently need specific therapies to target this tumor cell population. …”
Get full text

BIOLOGICAL CHARACTERISTICS, MECHANISM OF ACTION AND SOME STRATEGIES TO INCREASE NK CELL BIOMASS by Tran Thi Thanh Huong

“…Natural killer (NK) cells are a critical component of the innate immune system, capable of recognizing and eliminating pathogens without needing specific antigen presentation. Although NK cells have been studied for decades, many biological features and therapeutic applications remain unclear. …”
Get full text

The high adaptive potential of Abies alba Mill. seedlings – biochemical and physiological studies of succession along the environmental gradient of a Cambrian quarry by Agnieszka Szuba, Ewelina Ratajczak, Tomasz Leski, Dominik Tomaszewski, Izabela Ratajczak, Gabriela Woźniak, Andrzej M. Jagodziński

“…Abstract Abies alba Mill. (silver fir) needs specific soil and humidity conditions and seedlings are vulnerable to climatic extremes. …”
Get full text

Exofection by exosomes: A transient functional cargo transfer by Ramkumar Menon, Madhuri Tatiparthy, Jessica Selim, Isidore Mushimiyimana, Brinley Harrington, Awanit Kumar, Lauren Richardson, Emmanuel Amabebe, Ananth Kumar Kammala

“…Upon receiving the exosomal cargo, recipient cells transiently express and exhibit the functional activity of the delivered molecules. …”
Get full text

Patient voices and student insights into LGBTQ+ healthcare: a call for equitable healthcare through medical education by Michael X Fu, Simisola Onanuga, Xinyu Ye, Raksha Aiyappan, Tangming Zou, Susan Smith, Ana Baptista

“…Purpose Lesbian, gay, bisexual, transgender, queer, and other sexual and gender diverse (LGBTQ+) individuals have health needs specific to their identities. However, they face discrimination and cis-heteronormativity in most patient-provider interactions, which often translate into poor healthcare. …”
Get full text

Developing a Quality Improvement Framework to Enhance the Health System User Experience for Individuals Living With Type 1 Diabetes: The Reshape T1D Study by Jamie Boisvenue, Youssef A. Elezzabi, Kim Young, Kathleen Gibson, Heather Hinz, Reid McClure, Robyn Homulos, Jude Spiers, Peter Senior, Roseanne Yeung

“…Women expressed challenges in discussing reproductive health with their clinicians. …”
Get full text

Demand, utilization, and supply of community smart senior care services for older people in China by Ruobing Fa, Shengxuan Jin, Peng Fan, Fengyuan Tang, Qian Jin, Changqing Wang

“…Conclusion Older adults expressed a strong demand for smart ageing services; however, difficulties using smart technology remain a serious problem. …”
Get full text