PathCrisp: an innovative molecular diagnostic tool for early detection of NDM-resistant infections by Shrigouri Patil, Annes Siji, Dhrithi Mallur, B. S. Kruthika, Nazneen Gheewalla, Shraddha Karve, Maithili Kavathekar, Bansidhar Tarai, Mandar Naik, Vandana Hegde, Jayaprada Rangineni, Vaijayanti Gupta, Vijay Chandru, Bulagonda Eswarappa Pradeep, Reety Arora

“…Our assay demonstrated 100% concordance with the PCR-Sanger sequencing method, more commonly used. Additionally, the lack of the need for a kit-based DNA purification step, rather a crude extraction via heating, enables the direct use of culture samples. …”
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Primary Peritoneal Serous Cancer: A Case Report of a Tumor in the Rectovaginal Septum by Analy Herrera-Torres, Carlos Guadalupe Parra-Torres, Gabriela C. Alamilla García, María del Rocío Thompson Bonilla, Oscar Manuel García Córdova, Alfredo Padilla Martínez, Rodolfo Iván Lara Ruíz, Esther Ramírez Moreno

“…Tumor dissection and protective colostomy with loop sigmoid colon were performed. A pathological study gave a diagnosis of a high-grade peritoneal serous carcinoma with a micropapillary pattern. …”
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CAV-generated mobility data modeling mechanism for adaptive signal control by Wei Lin, Heng Wei, Lan Yang, Xiangmo Zhao

“…However, use of the CV/AV-generated data is still yet mature due to lack of the data process mechanism and models to integrate the data into the adaptive traffic signal control system. …”
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Responsible AI in structural engineering: a framework for ethical use by Vagelis Plevris, Haidar Hosamo

“…However, it also raises critical ethical and governance challenges—including bias, lack of transparency, accountability gaps, and equity concerns—which are particularly significant in a discipline where public safety is paramount. …”
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Achieving socio-economic resilience in neighborhood through nature-based solutions: A systematic review by Basem Hegazy, Laila Khodeir, Fatma Fathy

“…This highlights the critical need to shift towards incorporating Nature-Based Solutions (NBS) within urban neighborhoods. …”
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Realistic synthetic dataset generation for cyber-physical systems: a performance evaluation by Yaa Acquaah, Kaushik Roy

“…However, conducting data collection experiments on complex CPS are constrained by considerable cost, lack of expertise and time involved. Consequently, the availability of genuine CPS dataset is limited. …”
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Optimizing the learning rate for adaptive estimation of neural encoding models. by Han-Lin Hsieh, Maryam M Shanechi

“…Closed-loop neurotechnologies often need to adaptively learn an encoding model that relates the neural activity to the brain state, and is used for brain state decoding. …”
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Patient-Generated Collections for Organizing Electronic Health Record Data to Elevate Personal Meaning, Improve Actionability, and Support Patient–Health Care Provider Communicatio... by Drashko Nakikj, David Kreda, Karan Luthria, Nils Gehlenborg

“…Finally, collections might produce a misconstrued health picture, but bringing the physician in the loop for verification could increase their clinical validity. …”
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Molecular detection and identification of Trichobilharzia: development of a LAMP, qPCR, and multiplex PCR toolkit by Jan Procházka, Zikmund Bartoníček, Roman Leontovyč, Petr Horák, Tomáš Macháček

“…However, conventional methods, such as cercarial shedding and snail dissections, are labour-intensive and lack sensitivity. To overcome these limitations, we present a molecular toolkit that combines loop-mediated isothermal amplification (LAMP), quantitative polymerase chain reaction (qPCR), and multiplex PCR for rapid, sensitive, and accurate detection and identification of Trichobilharzia spp. from various biological samples. …”
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Enhancing seabed sediment classification with multibeam echo-sounding and self-training: a case study from the East Sea of South Korea by Changhoon Lee, Sujung Park, Daeung Yoon, Bo-Yeon Yi, Moonsoo Lim

“…Multibeam echo-sounding systems (MBES) offer broad coverage but lack detailed sediment characterization, creating a need for an integrated, data-driven approach.MethodsWe developed a machine-learning framework that fuses MBES backscatter data with limited seabed samples. …”
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Tuberculosis and diabetes mellitus: a narrative review on the growing syndemic in low- and middle-income countries by Ibrahim Khalil, Md. Imran Hossain

“…This review underscores the urgent need for tailored interventions and policies to improve patient care and public health outcomes in the context of TB-DM co-infection.…”
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DNA-Detection Based Diagnostics for Taenia solium Cysticercosis in Porcine by Maxwell W. Waema, Gerald Misinzo, John M. Kagira, Eric L. Agola, Helena A. Ngowi

“…In conclusion, several molecular methods have been developed and evaluated in lab settings. However, there is need to validate these methods as a diagnostic tool to diagnose porcine cysticercosis in low-resource areas.…”
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End-to-End Framework for Identifying Vulnerabilities of Operational Technology Protocols and Their Implementations in Industrial IoT by Matthew Boeding, Michael Hempel, Hamid Sharif

“…However, OT protocols often lack the rigor of cybersecurity capabilities that have become a critical characteristic of IT protocols. …”
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Microenvironment-feedback regulated hydrogels as living wound healing materials by Yibo Cheng, Yanwen Wang, Yunyi Wang, Poh-Ching Tan, Shiyun Yu, Chi Li, Zi-Yuan Li, Qing-Feng Li, Shuang-Bai Zhou, Chen Wang, Junji Zhang, He Tian

“…However, current prevailed biomaterials maintain a passively responsive mode and lack autonomous and interactive dynamics. Striving for a paradigm of microenvironment interactive and self-regulatory medical agents as next-generation of biomaterials is of desperate need. …”
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Heart Failure with Preserved Ejection Fraction in Egypt: An Expert Opinion by Magdy Abdelhamid, Amr Zaki Salem, Hamza Kabil, Hany Ragy, Hosam Hasan-Ali, Mohamed Elnoamany, Mohamed Elsetiha, Sameh Shaheen

“…All HFpEF patients should be treated through multidrug regimens tailored for their state, symptoms, and comorbidities, with sodium-glucose cotransporter-2 (SGLT2) inhibitors as the mainstay of treatment together with either one or a combination of loop diuretic and aldosterone antagonists. This paper provides an integrated review of epidemiology, means of diagnosis, current and novel pharmacological therapy options for HFpEF patients in the light of the recent advances in treatment of HFpEF, discussing means of healthcare delivery and unmet needs, and proposing recommendations for clinical practice and pathways for future research.…”
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50 Years of Antibody Numbering Schemes: A Statistical and Structural Evaluation Reveals Key Differences and Limitations by Zirui Zhu, Katherine S. Olson, Thomas J. Magliery

“…The Kabat and AbM numbering schemes tend to incorporate more conserved residues into their CDR definitions, whereas CDRs defined by the Chothia and IMGT numbering schemes display greater diversity, sometimes missing certain loop residues. Notably, we identify a critical residue, L29, within the kappa light chain CDR1, which appears to act as a pivotal structural point within the loop. …”
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External validation of the natriuretic response prediction equation to discriminate diuretic response in heart failure by Patricia Ramírez‐Sánchez, Alberto Falcón‐Aguirre, Antonio Tepayotl‐Aponte, Genaro H. Mendoza‐Zavala, Luis Olmos‐Dominguez, Adolfo Chavez‐Mendoza, José A. Magaña‐Serrano, José A. Cigarroa‐López, Moises Aceves‐Garcia, Jorge Rayo‐Chavez, Marcos J. Olalde‐Roman, Cristina Revilla‐Monsalve, Eduardo Almeida‐Gutierrez, Jonathan S. Chavez‐Iñiguez, Edith L. Posada‐Martinez, Juan B. Ivey‐Miranda

“…Abstract Aims Incomplete decongestion due to lack of titration of diuretics to effective doses is a common reason for readmission in patients with acute decompensated heart failure (ADHF). …”
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Monitoring Land Surface Temperature on Urban Expansion using Normalised Difference Vegetation Index and Google Earth Engine by Nur Suhaili Mansor, Hapini Awang, Chong Kar Min, Anna Bluszcz, Ade Candra, Shakiroh Khamis

“…Despite growing recognition of these impacts, many existing studies rely on static or predictive models that lack spatial precision and real-time monitoring. …”
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Emergent canine visceral leishmaniasis in Argentina: Comparative diagnostics and relevance to proliferation of human disease. by Kyoko Fujisawa, Charlotte Silcott-Niles, Poppy Simonson, Daniela Lamattina, Cristian A Humeres, Tapan Bhattacharyya, Pascal Mertens, Caroline Thunissen, Victoria O'Rourke, Magdalena Pańczuk, James A Whitworth, Oscar Daniel Salomón, Michael A Miles

“…In Argentina, canine (CVL) and human visceral leishmaniasis (HVL) have recently emerged. There is a lack of standardised diagnostic tests for CVL, which hinders control of CVL and HVL.…”
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Hospital pharmacy implementation of a unit dose dispensing system: A qualitative interview study to determine experiences, views and attitudes of nursing staff by Theodora Steindl-Schönhuber, Theresa Drechsel, Gunda Gittler, Anita Elaine Weidmann

“…Nurses commented on a lack in standardised workflow, erosion of knowledge and sustainability. …”
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