Treatment of bone complications in multiple myeloma patients by V. V. Ptushkin

“…Results of controlled clinical trials showed that such a medications as clodronate, pamidronate and zoledronate considerably decrease the incidence of bone complications in patients with multiple myelomas. …”
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Surgical treatment of patients with multiple brain metastases by D. M. Belov, V. B. Karakhan, A. Kh. Bekyashev, E. V. Mitrofanov, E. V. Prozorenko, V. A. Aleshin, R. A. Sufianov, D. R. Nashletashvili

“…However, these disorders were moderate and did not reach the extent of dementia. The work done shows.Conclusion. Surgical removal of all metastases in patients with multiple brain metastases provides a prognosis similar to that of patients undergoing surgery for single metastasis. …”
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The condition of the cardiovascular system in patients with relapsing-remitting multiple sclerosis by O. A. Traktirskaya, T. V. Adasheva, A. N. Boyko, E. V. Popova

“…The main indicators of echocardiography were within normal values, no significant differences between the groups were found.Conclusion. The study showed that multiple sclerosis patients are at risk of developing cardiovascular diseases and require increased attention to prevent the development.…”
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Efficiency of lenalidomide, bortezomib and prednisone (RVP) in patients with newly diagnosed multiple myeloma by K. A. Belousov, T. A. Mitina, Yu. Yu. Chuksina, A. K. Golenkov, E. V. Kataeva, E. V. Trifonova, Yu. B. Chernykh, L. L. Vysotskaya, S. G. Zakharov, E. F. Klinushkina, A. N. Mitin

“…Objective: to study the efficacy and safety of the antitumor RVP program (lenalidomide, bortezomib, prednisone) as a first-line therapy in patients with multiple myeloma (MM). Materials and methods. …”
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Bortezomib-induced peripheral neuropathy in patients with multiple myeloma: pain syndrome and psychopathological aspects by E. Z. Irugova, L. P. Mendeleeva, D. E. Vybornykh, M. V. Soloveva, S. Yu. Fedorova, M. V. Solovev

“…A study of patients’ psycho‑emotional states 100 days after auto‑HSCT showed a reduction in the frequency and severity of depressive states. …”
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Impact of Intraaortic Therapy on Metabolic Changes in Patients with Peritoneal Sepsis Complicated by Multiple Organ Dysfunction by A. Yu. Yakovlev, G. A. Boyarinov, I. V. Mukhina, Ye. V. Dudina

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Machine Learning for the Photonic Evaluation of Cranial and Extracranial Sites in Healthy Individuals and in Patients with Multiple Sclerosis by Antonio Currà, Riccardo Gasbarrone, Davide Gattabria, Nicola Luigi Bragazzi, Giuseppe Bonifazi, Silvia Serranti, Paolo Missori, Francesco Fattapposta, Carlotta Manfredi, Andrea Maffucci, Luca Puce, Lucio Marinelli, Carlo Trompetto

“…This study aims to characterize short-wave infrared (SWIR) reflectance spectra at cranial (at the scalp overlying the frontal cortex and the temporal bone window) and extracranial (biceps and triceps) sites in patients with multiple sclerosis (MS) and age-/sex-matched controls. …”
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The impact of 3-tesla breast MRI on the choice of the surgical plan in patients with multiple ipsilateral breast cancer by Bustan Mohamed Anwer, AlaaEldine AbdelHamid Mostafa, Eman ElBakoury, M. A. Elhussini, Hebatallah H. M. Hassan

“…Both modalities showed equivalent specificity (71.4%). In group B, MRI showed additional disease in 1/16 (6%). …”
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First-in-human experience of radiopharmaceutical therapy with [177Lu]Lu-DOTATATE in patients with advanced multiple myeloma by Wendy Delbart, Marie Vercruyssen, Rachele Danieli, Clémentine Marin, Zéna Wimana, Nathalie Meuleman, Patrick Flamen, Erwin Woff, Ioannis Karfis

“…One patient achieved sustained metabolic response and clinical stability over 12 months, while the second showed a complete metabolic response before experiencing biological progression. …”
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Comparative Effectiveness of Fumarates Versus Sphingosine-1-Phosphate Receptor Modulators in Black Patients with Multiple Sclerosis by Sophia Woodson, Edward J. Gettings, Chu-Yueh Guo, Sylvia Klineova, Jong-Mi Lee, Rebecca S. Romero, Aljoeson Walker, Nicholas Belviso, Sai L. Shankar, Jason P. Mendoza, Boyang Bian, James B. Lewin, Kinyee Fong

“…Kaplan–Meier analyses showed similar relapse-free proportions at 24 months (72.6% and 74.7% in fumerate and S1P populations, respectively; p = 0.152). …”
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Correlation Between Peripheral Blood Immune Cell Distribution and Disease Severity and Prognosis in Multiple Sclerosis Patients by Liu PJ, Yuan P, Liu SP

“…Disease severity and prognosis were assessed using the Expanded Disability Status Scale (EDSS) and Multiple Sclerosis Functional Composite (MSFC). Spearman correlation and multivariate linear regression (adjusted for age, gender, disease duration, and MS subtype) were employed to evaluate associations.Results: Of the MS patients studied, 10.4% (n=7) exhibited abnormal CSF pressure. …”
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CT-based auto-segmentation of multiple target volumes for all-in-one radiotherapy in rectal cancer patients by Xuemin Li, Luqi Wang, Mengying Yang, Xianan Li, Ting Zhao, Mingqing Wang, Siyi Lu, Yunsong Ji, Wei Zhang, Lecheng Jia, Ran Peng, Junjie Wang, Hao Wang

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Modern diagnostic potentials of studying structural and functional changes of the retina and the optic nerve in multiple sclerosis patients by A. Zh. Fursova, M. Yu. Zubkova, M. A. Vasilyeva, Yu. A. Gamza, N. A. Malkova, A. I. Prokaeva, F. K. Rabota

“…Purpose: to study significant functional and structural changes in the retina and the intraocular section of the optic nerve in multiple sclerosis (MS) patients and analyze how they are interrelated with electrophysiological changes in the visual analyzer.Materials and methods. …”
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Exploring what matters most to patients in relapsed refractory multiple myeloma treatment: a Canadian discrete choice experiment with patients, caregivers and physicians by Rebekah Hall, Gin Nie Chua, Bonnie Macfarlane, Richard K Plante, Kun Shi, Stephanie Soltys, Arleigh McCurdy, Martine Elias, Jessy Ranger

“…Abstract Background Relapsed/refractory multiple myeloma (RRMM) significantly impacts patients’ quality of life. …”
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Comparing cognitive impairment using MACFIMS in patients with multiple sclerosis and healthy controls: a systematic review and meta-analysis by Amirreza Nasirzadeh, Mohammad Mohammadi, Melika Arab Bafrani, Aynaz Mohammadi, Hossein Bakhtiari-Dovvombaygi

“…Methods This systematic review and meta-analysis aimed to evaluate cognitive function using the Minimal Assessment of Cognitive Function in Multiple Sclerosis (MACFIMS) battery among pwMS patients and healthy controls (HCs). …”
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Characteristics and correlations of sleep disorders in patients with relapsing–remitting multiple sclerosis in China: a cross-sectional study by Rongrong Wang, Tengteng Zhang, Han Wang, Yao Ren, Runze Zhao, Gaopan Zhang, Guoxun Zhang, Xiongfei Zhao

“…BackgroundSleep disorders are a major but overlooked symptom in patients with multiple sclerosis (MS).ObjectivesThis article aims to investigate the characteristics of sleep disorders in patients with relapsing–remitting multiple sclerosis (RRMS) and to analyze the correlations between sleep disorders in RRMS and anxiety, depression, fatigue, and cognitive impairment.MethodsA total of 35 patients with RRMS and 35 controls were included, and both groups underwent assessments for sleep, anxiety, depression, fatigue, and cognitive function.ResultsThe RRMS group and the control group showed significant differences in Pittsburgh Sleep Quality Index (PSQI), Athens Insomnia Scale (AIS), Insomnia Severity Index (ISI), Hamilton Anxiety Scale (HAMA), Hamilton Depression Scale (HAMD), Modified Fatigue Impact Scale (MFIS), and Montreal Cognitive Assessment (MoCA). …”
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Analysis and validation of characteristic genes in RNA sequencing datasets from heart failure patients based on multiple algorithms by Yuxuan Li, Ying Bai, Wujiao Wang, Zhaotian Ma, Peng Li, Dong Li, Sinai Li, Jialin Jin, Jialin Jin, Qian Lin

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Management of patients with multiple primary сancer in the practice of a modern oncologist. Case report and literature review by D. A. Khlanta, G. P. Gens

“…The increase in the cancer incidence, as well as the need to make difficult decisions about further treatment strategy, enhance the relevance of studying multiple primary malignant neoplasms. This review discusses the current positions of medicine in relation to this category of malignant neoplasms, and presents a case report of a patient with this disaese. …”
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Discovery and early validation of serum protein signatures in untreated multiple sclerosis patients: identification of candidate biomarkers for diagnosis and stratification by Isabel Brichette-Mieg, Isabel Brichette-Mieg, Ana Alonso-Torres, Ana Alonso-Torres, Pablo Aliaga-Gaspar, Pablo Aliaga-Gaspar, José-Luis Rodríguez-Bada, Virginia Reyes-Garrido, Virginia Reyes-Garrido, Patricia Urbaneja-Romero, Patricia Urbaneja-Romero, Carmen Muñoz, María Díaz-Sánchez, Elisa Martín-Montañez, María-del-Rosario Cabello-Porras, Begoña Oliver-Martos, Begoña Oliver-Martos, Laura Leyva, Laura Leyva

“…BackgroundDespite progress in serum biomarker research, reliable tools for early diagnosis and patient stratification in multiple sclerosis (MS) remain limited. …”
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Personalized Treatment Response in Progressive MS: Can the Patient's Profile Influence the Outcome? by Francesca Bovis, Ludwig Kappos, Sophie Arnould, Goeril Karlsson, Maria Pia Sormani

“…Conclusions This analysis demonstrated the ability to define responders to a therapy based on their baseline profile and evaluate the treatment effect on multiple endpoints, showing that the benefit on different outcomes can vary across patients.…”
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