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Whole blood transcriptomics analysis of Indonesians reveals translocated and pathogenic microbiota in blood.
Published 2025-01-01“…Yet, Flaviviridae and Plasmodium stood out as the most predominantly abundant taxa, particularly in samples from the easternmost island within our Indonesian dataset. …”
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142
Universal receptive system as a novel regulator of transcriptomic activity of Staphylococcus aureus
Published 2025-01-01“…KEGG pathway gene enrichment analysis revealed that the most upregulated pathways following TezR inactivation included those related to energy metabolism, cell wall metabolism, and secretion systems. …”
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143
Comparative transcriptomics of transgenic tobacco plants overexpressing Miscanthus sinensis BTF3
Published 2025-05-01“…This study was conducted to expand our understanding on plant transcriptome changes as there are no reports on plant transcriptome changes in normal environments due to the overexpression of Miscanthus sinensis BTF3 gene. …”
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144
Integration of metabolomics and transcriptomics to reveal anti-immunosuppression mechanism of Lycium barbarum polysaccharide
Published 2024-11-01“…The integrated examination of transcriptomic and metabolomic data revealed that the glycerophospholipid metabolic pathway stands out as the most significant among all metabolic pathways. …”
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145
The developmental transcriptome dynamics of current-year shoot utilized as scion in Camellia chekiangoleosa
Published 2025-05-01“…Abstract Background Camellia chekiangoleosa is the most widely planted red-flowered and large-fruited oil-camellia species, with high value in edible oil production and landscaping. …”
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146
Determining Prostate Cancer-Related Pathways and the Role of the RPH3AL Gene
Published 2024-12-01“…Among the five most over-expressed genes, RPH3AL was the most prominent.Conclusion: RPH3AL is a potential biomarker for prostate cancer based on transcriptomic profiling. …”
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147
Transcriptomic Analysis of Biofilm Formation Inhibition by PDIA Iminosugar in <i>Staphylococcus aureus</i>
Published 2025-07-01“…<b>Background:</b> Iminosugars are natural or synthetic sugar analogues with a very broad spectrum of activities, including those against the most prominent bacterial pathogens, like <i>P. aeruginosa</i> or <i>S. aureus.…”
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148
Integrated transcriptomic and metabolomic analyses reveal the molecular mechanism of flower color differentiation in Orychophragmus violaceus
Published 2025-02-01“…Comparative analysis of the metabolites among the three flower samples revealed that two anthocyanins, peonidin-3-glucoside and delphinidin 3-(6’’-malonyl-glucoside), are the pigments most likely responsible for the coloration of the petals of O. violaceus. …”
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149
Genomic, transcriptomic and epigenomic signatures of ageing and cold adaptation in the Antarctic clam Laternula elliptica
Published 2025-05-01“…In this study, we describe and analyse the genome of L. elliptica and use it as a tool to understand transcriptomic responses to shell damage across different age cohorts. …”
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150
Transgenerational toxicity assessment of [C8mim]Br: Focus on early development, antioxidant defense, and transcriptome profiles in zebrafish
Published 2025-02-01“…1-Methyl-3-octylimidazolium bromide ([C8mim]Br), one of the most widely used and studied ionic liquids, is a contaminant of emerging concern. …”
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151
Molecular Mechanisms Underlying Salt Tolerance in Maize: A Combined Transcriptome and Metabolome Analysis
Published 2025-07-01“…Maize (<i>Zea mays</i> L.) is one of the most important food crops. Salt stress can hinder crop growth and development, but the molecular mechanisms underlying maize’s response to salt tolerance remain unclear. …”
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152
Single‐Cell Transcriptomics Reveals a Pivotal Role of DOCK2 in Sjögren Disease
Published 2024-12-01“…By analyzing the transcriptomic data and employing clustering analysis, a specific target was identified, leading to the treatment of mice with a targeted inhibitor. …”
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153
The effect of visfatin on the transcriptomic profile of porcine anterior pituitary cells during periimplantation period
Published 2025-05-01“…Visfatin, a hormone belonging to the adipokines family, may belong to a group of factors regulating the reproductive functions in response to the female’s metabolic status. Herein we verified the hypothesis assuming a modulatory effect of visfatin on the porcine anterior pituitary transcriptome on days 15 to 16 of gestation (beginning of implantation). …”
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154
Differential expression and correlation analysis of global transcriptome for obstructive sleep apnea hypopnea syndrome
Published 2025-04-01“…By constructing a quaternary network miR-8485 and miR-6089 were found to be the top two ranked miRNAs most closely associated with OSAHS. Both qRT-PCR and transcriptome sequencing analysis showed similar trends. …”
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155
Transcriptomic Analysis of Tambaqui (<i>Colossoma macropomum</i>) Exposed to Trichlorfon-Induced Toxicity
Published 2025-06-01Get full text
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156
Transcriptomic analysis reveals the mechanism underlying salinity-induced morphological changes in Skeletonema subsalsum
Published 2024-10-01“…Although studies have shown that salinity induces morphological plasticity changes in diatom cell walls, most research has focused on physiological responses rather than molecular mechanisms. …”
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Genomic and Transcriptomic Profiles in Smokers and Never-Smokers Lung Squamous Cell Carcinoma Patients
Published 2025-06-01“…TruSight Oncology® 500, investigating hotspots in 523 cancer-related genes, Tumor mutation burden (TMB) and microsatellite instability (MSI), and RNA sequencing was performed on tumor tissue. Genomic and transcriptomic profiles were compared between smokers and never-smoker patients.Results: The most frequently altered genes were TP53 (67%), CDKN2A (20%) and PIK3CA (17%), with no substantial differences between groups, except for TP53 which was more frequently mutated in smokers (86.7% vs 46.7%, p = 0.05), who also showed a higher TMB with respect to non-smokers (median 11 mut/Mb vs 5.5 mut/Mb, p = 0.028); all patients were stable for MSI score (median 1.87 vs 1.82, p = 0.87). …”
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160
Transcriptome analysis of Aedes aegypti midgut and salivary gland post-Zika virus infection
Published 2025-01-01“…Our findings demonstrate that Ae. aegypti exhibit distinct transcriptomic changes in response to ZIKV infection. …”
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