Membrane transporter genes predict chemoradiotherapy response in patients with cervical cancer by Natália Gregório Custódio, Fábio Ribeiro Queiroz, Angelo Borges de Melo Neto, Brenda Martins Cavalcante, Laurence Rodrigues do Amaral, Telma Maria Rossi de Figueiredo Franco, Matheus de Souza Gomes, Vasco Ariston de Carvalho Azevedo, Letícia da Conceição Braga, Paulo Guilherme de Oliveira Salles, Wander de Jesus Jeremias

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Pregnancy exacerbates neutrophil responses in murine lungs and alters gut microbiota composition after cigarette smoke exposure by Ali Dehghani, Ali Dehghani, Lei Wang, Lei Wang, Johan Garssen, Johan Garssen, Eirini Styla, Thea Leusink-Muis, Ingrid van Ark, Gert Folkerts, Jeroen van Bergenhenegouwen, Jeroen van Bergenhenegouwen, Saskia Braber, Saskia Braber

“…DiscussionIn conclusion, pregnancy as well as CS exposure induce differences in lung transcriptomic responses which might drive exacerbated lung inflammatory responses measured as neutrophil influx and activity. …”
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The Exon-Based Transcriptomic Analysis of Parkinson’s Disease by Sulev Kõks

“…At the same time, control subjects had only minimal changes that can mostly be attributed to being related to aging. Differentially regulated exons we identified in the PD cohort were mostly related to different aspects of the pathophysiology of PD, such as an innate immune response or lysosomal activity. …”
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Genotype-driven sensitivity of mice to tick-borne encephalitis virus correlates with differential host responses in peripheral macrophages and brain by Michaela Berankova, Jiri Holoubek, Vaclav Hönig, Zuzana Matusova, Martin Palus, Jiri Salat, Imtissal Krayem, Jarmila Vojtiskova, Pavel Svoboda, Veronika Pranclova, Lukas Valihrach, Peter Demant, Marie Lipoldova, Daniel Ruzek

“…Macrophages from both sensitive strains demonstrated elevated chemokine and proinflammatory cytokine production upon infection, whereas the resistant strain, STS, showed no cytokine/chemokine activation. Transcriptomic analysis of brain tissue demonstrated that the genetic background of the mouse strains dictated their transcriptional response to infection. …”
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Transcriptomic insights into Candida albicans adaptation to an anaerobic environment by Karen D. Zeise, John R. Erb-Downward, Gary B. Huffnagle

“…While much research has been done to identify mechanisms underlying adaptation to hypoxia (i.e., low oxygen), this is the first study evaluating the global transcriptomic response of C. albicans to anoxia (no oxygen). …”
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Unveiling the wheat-rust battleground: A transcriptomic journey by K.K. Chetan, Vaibhav Kumar Singh, Mohammad Waris Haider, Mahender Singh Saharan, Ravinder Kumar

“…The evolutionary relationship between wheat (host) and Puccinia (pathogen) renders existing wheat resistance ineffective over time. The most viable solution to this issue lies in the development of new resistant wheat varieties. …”
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Evaluating sex-specific responses to western diet across the lifespan: impact on cardiac function and transcriptomic signatures in C57BL/6J mice at 530 and 640/750 days of age by Ani Stepanyan, Agnieszka Brojakowska, Roksana Zakharyan, Siras Hakobyan, Suren Davitavyan, Tamara Sirunyan, Gisane Khachatryan, Mary K. Khlgatian, Malik Bisserier, Shihong Zhang, Susmita Sahoo, Lahouaria Hadri, Amit Rai, Venkata Naga Srikanth Garikipati, Arsen Arakelyan, David A. Goukassian

“…Abstract Background Long-term consumption of Western Diet (WD) is a well-established risk factor for the development of cardiovascular disease (CVD); however, there is a paucity of studies on the long-term effects of WD on the pathophysiology of CVD and sex-specific responses. Methods Our study aimed to investigate the sex-specific pathophysiological changes in left ventricular (LV) function using transthoracic echocardiography (ECHO) and LV tissue transcriptomics in WD-fed C57BL/6 J mice for 125 days, starting at the age of 300 through 425 days. …”
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Transcriptome sequencing and annotation for the Jamaican fruit bat (Artibeus jamaicensis). by Timothy I Shaw, Anuj Srivastava, Wen-Chi Chou, Liang Liu, Ann Hawkinson, Travis C Glenn, Rick Adams, Tony Schountz

“…The Jamaican fruit bat transcriptome dataset is a resource that should provide additional candidate markers for studying bat evolution and ecology, and tools for analysis of the host response and pathology of disease.…”
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Transcriptomic Analysis of Peripheral Blood Mononuclear Cells in Hyperuricemia and Gout by Valentin NICA, Medeea BADII, Orsolya GAAL, Georgiana CABĂU, Andreea-Manuela MIREA, Ioana HOTEA, Cristina PAMFIL, Simona REDNIC, Radu A. POPP, Yang LI, Tania O. CRIŞAN, Leo A.B. JOOSTEN

“… Background and Aim: Gout is one of the most common forms inflammatory arthritis characterized by deposits of monosodium urate crystals in joints, with an infiltration of neutrophils and macrophages. …”
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Transcriptome analysis of historic olives reveals stress-specific biomarkers by Hamad A. Alkhatatbeh, Monther T. Sadder, Nizar Haddad, Nizar Haddad, Ibrahim Al-Amad, Mohammad Brake, Nawal A. Alsakarneh, Abdulsalam M. Alnajjar

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Identification and comparative analysis of genes in response to cold stress between two mainly cultivated tetraploid cottons by QI Bowen, GUO Menglan, LU Hejun, MEI Huan, ZHAO Ting, FANG Lei

“…According to the orthologs between TM-1 and Hai7124, there were 1 518 and 3 577 specific response genes in TM-1 and Hai7124, respectively. Gene ontology (GO) enrichment and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis showed that the specific response genes in TM-1 were mostly involved in hormone signal transduction, circadian rhythm, and other regulation processes, while specific response genes in Hai7124 were mostly involved in amino acid metabolism processes such as lysine, arginine, serine and threonine. …”
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Comparative Transcriptome Analysis of Temperature-Induced Green Discoloration in Garlic by Ningyang Li, Zhichang Qiu, Xiaoming Lu, Bingchao Shi, Xiudong Sun, Xiaozhen Tang, Xuguang Qiao

“…Green discoloration is one of the most important problems that cause low quality of product in the processing of garlic, which can be induced by low-temperature stress. …”
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Spatiotemporal dynamic changes of meningeal microenvironment influence meningeal lymphatic function following subarachnoid hemorrhage: from inflammatory response to tissue remodeli... by Bingrui Zhu, Changming Liu, Ming Luo, Jiarui Chen, Sixuan Tian, Tiantong Zhan, Yibo Liu, Haocheng Zhang, Zhen Wang, Jianmin Zhang, Yuanjian Fang, Sheng Chen, Xiaoyu Wang

“…Notably, placental growth factor (PGF) emerged as the most prominent ligand within the VEGF signaling pathway received by meningeal lymphatic endothelial cells (mLECs) post-SAH. …”
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Transcriptome analysis of aerotolerant and aerosensitive Campylobacter jejuni strains in aerobic conditions by Elise Delaporte, Anand B. Karki, Anand B. Karki, Mohamed K. Fakhr

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Field-crop transcriptome models are enhanced by measurements in systematically controlled environments by Yoichi Hashida, Daisuke Kyogoku, Suguru E. Tanaka, Naoya Mori, Takanari Tanabata, Hiroyuki Watanabe, Atsushi J. Nagano

“…Conclusions Our results highlight the utility of a systematic sampling approach under controlled environments to understand the mechanism of plant environmental response and to improve transcriptome prediction under field environments.…”
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Transcriptome atlas of Striga germination: Implications for managing an intractable parasitic plant by Gilles Irafasha, Sylvia Mutinda, Fredrick Mobegi, Brett Hale, George Omwenga, Asela J. Wijeratne, Susann Wicke, Emily S. Bellis, Steven Runo

“…Societal Impact Statement Witchweeds, parasitic plants of the genus Striga, are nicknamed “cereal killers” because of their devastating destruction of Africa's most staple cereals, including maize, sorghum, millets, and upland rice. …”
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Metabolomics and Transcriptome Analysis of Rapeseed Under Salt Stress at Germination Stage by Menglin Zhou, Xi Song, Qingqing Yu, Bingbing Dai, Wei Zhou, Xiaofei Zan, Wuming Deng

“…This study integrates transcriptomic and metabolomic analyses to elucidate the molecular and physiological mechanisms underlying the salt stress response during the germination of the rapeseed variety ZS11. …”
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New Insights in the Sugarcane Transcriptome Responding to Drought Stress as Revealed by Supersage by Éderson Akio Kido, José Ribamar Costa Ferreira Neto, Roberta Lane de Oliveira Silva, Valesca Pandolfi, Ana Carolina Ribeiro Guimarães, Daniela Truffi Veiga, Sabrina Moutinho Chabregas, Sérgio Crovella, Ana Maria Benko-Iseppon

“…The present report analyzes the sugarcane transcriptome under drought stress, using a combination of high-throughput transcriptome profiling by SuperSAGE with the Solexa sequencing technology, allowing the identification of potential target genes during the stress response.…”
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Sexual dimorphism in lung transcriptomic adaptations in fetal alcohol spectrum disorders by Vishal D. Naik, Dylan J. Millikin, Daniel Moussa, Hong Jiang, Alexander L. Carabulea, Joseph D. Janeski, Jiahui Ding, Kang Chen, Marta Rodriguez-Garcia, Sunil Jaiman, Stephen A. Krawetz, Gil Mor, Jayanth Ramadoss

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Single-Cell Transcriptome Analyses of Four Pain Related Genes in Osteosarcoma by Mesalie Feleke, Haiyingjie Lin, Yun Liu, Liang Mo, Emel Rothzerg, Dezhi Song, Jinmin Zhao, Wenyu Feng, Jiake Xu

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