FB5P-seq-mAbs: monoclonal antibody production from FB5P-seq libraries for integrative single-cell analysis of B cells by Sakina Ado, Chuang Dong, Noudjoud Attaf, Myriam Moussa, Agathe Carrier, Agathe Carrier, Pierre Milpied, Jean-Marc Navarro

“…Parallel analysis of phenotype, transcriptome and antigen receptor sequence in single B cells is a useful method for tracking B cell activation and maturation during immune responses. …”
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Deletion of Clusterin Protects Cochlear Hair Cells against Hair Cell Aging and Ototoxicity by Xiaochang Zhao, Heidi J. Henderson, Tianying Wang, Bo Liu, Yi Li

“…Hearing loss is a debilitating disease that affects 10% of adults worldwide. Most sensorineural hearing loss is caused by the loss of mechanosensitive hair cells in the cochlea, often due to aging, noise, and ototoxic drugs. …”
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Comparison of stromal vascular fraction cell composition between Coleman fat and extracellular matrix/stromal vascular fraction gel by Xiaoyun Li, Guohong Zhang, Mengmeng Wang, Changhao Lu, Guangping Zhang, Zhehui Chen, Yingchang Ji

“…Downregulated DEGs were mainly associated with inflammatory and immune responses, and enriched in fat macrophages. M2 macrophages, resting CD4+ memory T cells, M1 macrophages, resting mast cells, and M0 macrophages ranked in the top five most prevalent immune cells in the two groups. …”
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The cyclase-associated protein contributes to antifungal susceptibility and virulence in Aspergillus fumigatus by Xinyu Yang, Qian Wang, Binghan Xiao, Qiqi Wang, Weiwei Deng, Nir Osherov, Ruoyu Li, Wei Liu

“…ΔCAP showed a reduced growth rate, abnormal hyphal development, and increased susceptibility to cell wall-perturbing agents (Congo red, calcofluor white, and SDS), oxidative stress-inducing agents (H2O2 and menadione), calcineurin inhibitors (FK506 and CsA), and voriconazole (VRC) and itraconazole. Transcriptome analysis revealed that differentially expressed genes responsible for regulating growth, hyphal development, cell wall synthesis, stress responses and antifungal susceptibility were identified in ΔCAP. …”
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Identification and Characterization of SWEET Gene Family in Peanuts and the Role of AhSWEET50 in Sugar Accumulation by Tiecheng Cai, Yijing Pan, Chong Zhang, Lang Chen, Biaojun Ji, Qiang Yang, Faqian Xiong, Weijian Zhuang

“…Transcriptome profiling highlighted <i>AhSWEET50</i> as the most highly expressed member during early seed development stages in both low- and high-sucrose peanut cultivars and also highly expressed at the mature stage. …”
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Genome-wide identification and expression analysis of the PIN gene family in the pepper pedicel abscission zone and during root development by HE Lei, YAN Xi, LAI Wei, LIU Chongzheng, YANG Hong, HE Jianwen

“…CaPINs encompass a multitude of elements associated with growth, environmental responses, and hormonal signaling. Transcriptome data analysis revealed that the expression of CaPINs in pepper was tissue-specific. …”
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The current state and problems of studying the biological effects of THz irradiation by E. A. Butikova, I. A. Razumov, O. V. Poveshchenko, V. V. Kanygin

“…Special attention is paid to the use of offi e technologies, in particular metabolomics, proteomics, transcriptomics to study the eff ts of THz on living systems. …”
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Searching for genes determining the APR phenotype in rye by Joanna Szewińska, Mateusz Matuszkiewicz, Monika Rakoczy-Trojanowska, Magdalena Święcicka, Marianna Krysińska, Wojciech Wakuliński

“…The analysis of the expression of selected ScLr_ABC and ScLr_SUG genes carried out on plants infected with fungal spores collected from locations where phenotypic assessments were performed. Most of the analyzed genes did not show any clear association between APR to LR. …”
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Characteristics of folic acid metabolism-related genes unveil prognosis and treatment strategy in lung adenocarcinoma by Yanting Dong, Xiaoyan Wang, Chuanchuan Dong, Peiqi Li, Zhuola Liu, Xinrui Tian

“…Abstract Background Lung adenocarcinoma (LUAD) is the most common subtype of lung cancer. Folic acid metabolism-related genes (FAMGs) have received increased attention because of their distinct role in DNA synthesis and repair. …”
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Identification of the Plant Defensin (MsPDF) Gene Family in <i>Medicago sativa</i> and Analysis of Expression Patterns Under Abiotic Stress by Meiyan Guo, Xiuhua Chen, Shuaixian Li, Jiang Tian, Wangqi Huang, Yongjun Shu

“…Transcriptome and qRT-PCR analyses showed that most of the <i>MsPDF</i> genes were significantly up-regulated under cold, drought, and salinity stresses. …”
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Integrating microplastic research in sustainable agriculture: Challenges and future directions for food production by Marcelo Illanes, María-Trinidad Toro, Mauricio Schoebitz, Nelson Zapata, Diego A. Moreno, María Dolores López-Belchí

“…Currently, the application of omics technologies, including genomics, transcriptomics, and metabolomics, offers novel insights into molecular mechanisms that enable the identification of specific biomarkers associated with MP exposure. …”
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Research progress of genome-wide association study by Duan Zhongqu, Zhu Jun

“…Three possible factors were responsible for the failure of detecting the cause loci. …”
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Identification of lipid metabolism-related genes in myocardial infarction: implications for diagnosis and therapy by Qiang Wang, Xian Wu, Bo Yu

“…They influence inflammatory responses and modulate leukocyte, vascular cell and cardiac cell functions, affecting the vasculature and heart. …”
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The pathogenesis of foot-and-mouth disease virus: current understandings and knowledge gaps by Carolina Stenfeldt, Michael Eschbaumer, John Humphreys, Gisselle N. Medina, Jonathan Arzt

“…Abstract Foot-and-mouth disease (FMD) continues to be one of the most important diseases of livestock globally based upon both biological features and regulatory aspects. …”
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Restoring mitophagy in prostate cancer cells: the role of miR-141 rescue in counteracting MAPK1/ERK2-dependent autophagy suppression by Radostina Tsvetankova, Ilka Tsvetkova, Soren Hayrabedyan, Krassimira Todorova

“…Prostate cancer (PCa) stands as one of the most prevalent malignancies in men, ranking as the fifth leading cancer-associated mortality. …”
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Sparstolonin B potentiates the antitumor activity of nanovesicle-loaded drugs by suppressing the phagocytosis of macrophages in vivo by Yuefeng Zhang, Zuo Mou, Wei Song, Xiaoqin He, Qin Yi, Zhekai Wang, Xietong Mao, Wei Wang, Yangtao Xu, Yang Shen, Peng Ma, Kaihuan Yu

“…Seven genes of interest were selected via transcriptome sequencing and validated via RT‒PCR. These results confirmed that the TLR2 signaling pathway is responsible for phagocytosis. siTLR2 and its inhibitor sparstolonin B (SpB) significantly inhibited the internalization of NVs by Mφs and downregulated the activity of the TLR2 pathway. …”
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Lactate activates trained immunity by fueling the tricarboxylic acid cycle and regulating histone lactylation by Huanhuan Cai, Xueyuan Chen, Yan Liu, Yingbo Chen, Gechang Zhong, Xiaoyu Chen, Shuo Rong, Hao Zeng, Lin Zhang, Zelong Li, Aihua Liao, Xiangtai Zeng, Wei Xiong, Cihang Guo, Yanfang Zhu, Ke-Qiong Deng, Hong Ren, Huan Yan, Zeng Cai, Ke Xu, Li Zhou, Zhibing Lu, Fubing Wang, Shi Liu

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Esculetin inhibits the PI3K/Akt/mTOR pathway and enhances anti-colorectal cancer activity via binding to ENO1 by Jianing Ma, Miaomiao Zhang, Shulipan Mulati, Xinhua Nabi, Xinhua Nabi, Xinhua Nabi, Xinhua Nabi, Weiyi Zhang, Weiyi Zhang, Weiyi Zhang, Weiyi Zhang

“…The molecular mechanisms of Esc’s antitumor properties were elucidated through network pharmacology, transcriptome sequencing technology, drug affinity responsive target stability (DARTS), and molecular docking. …”
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Identification of signaling networks associated with lactate modulation of macrophages and dendritic cells by Rapeepat Sangsuwan, Bhasirie Thuamsang, Noah Pacifici, Phum Tachachartvanich, Devan Murphy, Abhineet Ram, John Albeck, Jamal S. Lewis

“…Dendritic cells (DCs) and macrophages (MΦs) are specialized antigen-presenting cells serving as key players in innate immunity and anticancer-associated immune responses. Although most studies have shown that lactate affects immune phenotypes (e.g., surface protein expression and cytokine production), the cell signaling network mediated by lactate is not fully understood. …”
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Multi‐omics profiling reveals key factors involved in Ewing sarcoma metastasis by Mariona Chicón‐Bosch, Sara Sánchez‐Serra, Marta Rosàs‐Lapeña, Nicolás Costa‐Fraga, Judit Besalú‐Velázquez, Janet Illa‐Bernadí, Silvia Mateo‐Lozano, Florencia Cidre‐Aranaz, Thomas G.P. Grünewald, Ángel Díaz‐Lagares, Roser Lopez‐Alemany, Òscar M. Tirado

“…Ewing sarcoma (EWS) is the second most common bone tumor affecting children and young adults, with dismal outcomes for patients with metastasis at diagnosis. …”
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