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Comprehensive RNA-Seq profiling of the lung transcriptome of Bashbay sheep in response to experimental Mycoplasma ovipneumoniae infection.
Published 2020-01-01“…Gene Ontology analysis showed that differentially expressed genes in different groups were enriched for 1580 and 4561 terms, where those most closely related to M. ovipneumoniae infection are positive regulators of inflammatory responses (p < 0.01). …”
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The Role of Genomics and Transcriptomics in Characterizing and Predicting Patient Response to Treatment in Triple Negative Breast Cancer (TNBC)
Published 2025-04-01“…Of the subtypes of breast cancer, the most aggressive subtype is triple negative breast cancer (TNBC) due to its lack of targets that could be leveraged for treatment in other subtypes. …”
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De novo assembly of the common bean transcriptome using short reads for the discovery of drought-responsive genes.
Published 2014-01-01“…The common bean (Phaseolus vulgaris L.) is one of the most important food legumes, far ahead of other legumes. …”
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Transcriptome and Small-RNA Sequencing Reveals the Response Mechanism of <i>Brassica napus</i> to Waterlogging Stress
Published 2025-04-01“…Notably, six upregulated TFs in leaves were associated with the ethylene response and were predicted targets of bna-miR172 family members, and four TFs in roots participated in the ethylene response pathway. …”
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Metabolome and transcriptome analyses for explore heat stress responses and adaptation mechanisms in Rhododendron henanense subsp. lingbaoense
Published 2025-03-01“…It was speculated that these DEGs are related to the response of Rhl to high temperature stress (HTS). Overall, 9 TF families might be the key regulators of Heat stress response pathways in Rhl. …”
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Peanut leaf transcriptomic dynamics reveals insights into the acclimation response to elevated carbon dioxide under semiarid conditions
Published 2025-03-01“…We evaluated a comparative leaf transcriptomic profile across three periodic water deficit/re-hydration (well-watered/recovery) cycles throughout the growing season using RNAseq analysis.ResultsOur results showed that the transcriptome responses were influenced by [CO2], water availability, and developmental stages. …”
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Root Ethylene and Abscisic Acid Responses to Flooding Stress in <i>Styrax japonicus</i>: A Transcriptomic Perspective
Published 2025-06-01“…KEGG enrichment analysis revealed that the most prominently enriched pathway for DEGs was plant hormone signal transduction under both waterlogging and submergence stress, with 314 and 370 DEGs identified, respectively. …”
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Comparative Transcriptomic Profiling Reveals Divergent Drought-Response Mechanisms Between Resistant and Susceptible Apple Genotype Roots
Published 2025-03-01“…Although there is an increasing studies concerning the molecular mechanism in apple response to drought, most of these studies focus on the leaves. …”
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A study on the hepatic response to heat stress in Gymnocypris eckloni through an approach combining metabolomic and transcriptomic profiling
Published 2024-12-01“…In this study, G. eckloni was subjected to both chronic and acute heat stress, with subsequent analysis focusing on changes in the pathological and physiological characteristics and transcriptomic and metabolic responses of the liver to high temperature. …”
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Transcriptomic analysis of maize leaves under different irrigation treatments in field conditions
Published 2025-03-01“…Abstract Objectives As one of the most widely cultivated agricultural crops in the world, maize (Zea mays L.) yield is often affected by water stress. …”
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Transcriptomic Analysis of Cell Stress Response in <i>Wickerhamomyces anomalus</i> H4 Under Octanoic Acid Stress
Published 2024-11-01“…At 400 mg/L, only 130 DEGs were detected, suggesting a more limited response. KEGG pathway analysis indicated that most DEGs at 200 mg/L were associated with the “ribosome” and “proteasome” pathways, reflecting disruptions in protein synthesis and turnover. …”
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Unique transcriptomic responses of rat and human alveolar macrophages in an in vitro model of overload with TiO2 and carbon black
Published 2025-04-01“…Methods Primary rat and human alveolar macrophages were exposed in vitro to control, non-overload or overload doses of titanium dioxide (P25) or carbon black (Printex 90) particles, and their activation profile was examined by untargeted transcriptomics. Results Rat macrophages were largely the most responsive to particle overload. …”
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Integrative Transcriptomic and Metabolomic Analysis Reveals Quinoa Leaf Response Mechanisms to Different Phosphorus Concentrations During Filling Stage
Published 2024-11-01“…Specifically, through a combined analysis of ultra-performance liquid chromatography–tandem mass spectrometry and transcriptome analysis, we identified the alteration and regulation of specific metabolites and genes within flavonoid biosynthesis pathways; this comprehensive evaluation helped elucidate the response mechanism of quinoa leaves during the grouting stage under various phosphorus conditions. …”
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Comparative transcriptome analysis reveals differences in immune responses to copper ions in Sepia esculenta under high-temperature conditions
Published 2025-03-01“…In this study, we used transcriptomic techniques to investigate the differences in Cu exposure immune responses in S. esculenta larvae under different temperature conditions. …”
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Integrated transcriptome and metabolome analysis revealed differential drought stress response mechanisms of wheat seedlings with varying drought tolerance
Published 2025-05-01“…Integrated metabolome and transcriptome analyses demonstrated significant up-regulation of most flavonoids and phenolic acids biosynthesis-related metabolites and genes (HCT, FLS, CHS and F3’5’H) in T13 under drought stress. …”
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Comparative transcriptomic analysis reveals the important role of hepatic fatty acid metabolism in the acute heat stress response in chickens
Published 2025-07-01“…Conclusions The critical role of hepatic fatty acid metabolism in mediating the acute heat stress response in chickens was revealed by a multi-tissue comparative transcriptome, and it was determined that FASN provides actionable insights into improving heat tolerance in poultry through metabolic interventions.…”
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Comparative transcriptome analysis of differentially expressed genes of Medicago falcata L. breeding lines response to saline-alkaline stress
Published 2025-05-01“…Furthermore, physiological indicators such as chlorophyll content, proline accumulation, and superoxide dismutase (SOD) activity were assessed to compare the responses of LM18 and HL to salt-alkali stress. By integrating transcriptomic and physiological analyses, this study provides new insights into the physiological and molecular regulatory mechanisms of M. falcata in response to salt-alkali stress. …”
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Color-dependent defense mechanisms of Quinoa (Chenopodium quinoa Willd.) against Spodoptera exigua: metabolomic and transcriptomic insights
Published 2025-07-01“…Abstract Background Quinoa (Chenopodium quinoa Willd.) exhibits a diverse and complex response to various organisms and environmental factors. …”
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