Identification of cepharanthine as an effective inhibitor of African swine fever virus replication by Chuanxiang Qi, Jiyoung Lee, Yongqiang Zhang, Huan Chen, Jiaxuan Lv, Zhenzhong Wang, Jinming Li, Xiaodong Wu, Yong-Sam Jung, Zhiliang Wang, Yingjuan Qian

“…Cepharanthine (CEP), a bisbenzylisoquinoline alkaloid, was the most potent inhibitor effect with an IC50 of 0.3223 μM. …”
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Genome-wide identification and analysis of the WRKY gene family in Sainfoin (Onobrychis viciifolia) and their response to drought, salt, and alkali stress by Wenxiang Li, Yinuo Yan, Yanxia Liang, Shiyao Yue, Yaling Liu, Feng Yuan, Mengrong Xu, Dengxia Yi, Jun Li, Yan Zhao, Lili Nan, Wenbo Jiang

“…Collinearity analysis identified 232 duplicated gene pairs, including four tandem repeat pairs, indicating role of segmental duplication in the expansion of the OvWRKY gene family. Transcriptome analysis revealed that highly expressed genes under drought, salt, and alkali stress mostly belonged to groups I, III, IId, IIa, and IIb. …”
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Transcriptional time-course analysis during ash dieback infection revealed different responses in tolerant and susceptible Fraxinus excelsior genotypes by Víctor Chano, Renata Callegari Ferrari, Tania Domínguez-Flores, Karuna Shrestha, Barbara Fussi, Hannes Seidel, Oliver Gailing, Katharina B. Budde

“…The analysis yielded 395 and 500 Differentially Expressed Genes (DEGs) along the response for ADB-tolerant FAR3 and FS36, respectively, while ADB-susceptible UW1 and UW2 revealed 194 and 571 DEGs, respectively, with most DEGs found exclusively in just one of the genotypes. …”
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Bacillus velezensis QSE-21 cell-free supernatant primes resistance and outperforms live cells in controlling Botrytis cinerea on tomato by Saisai Gao, Hongjia Han, Hongjia Han, Fan Yang, Xinyang Liu, Wenxing Liang, Mengjie Liu

“…Cell-free supernatants (CFSs), derived from BCA fermentation, contain most active biocontrol compounds responsible for disease suppression and can be directly applied without introducing living organisms into the environment. …”
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Integrative multiomics analysis reveals the subtypes and key mechanisms of platinum resistance in gastric cancer: identification of KLF9 as a promising therapeutic target by Pengcheng Zhang, Lexin Wang, Haonan Lin, Yihui Han, Jingfang Zhou, Hang Song, Peng Wang, Huanhuan Tan, Yajuan Fu

“…Patients with subtype CS2 also exhibited the most adverse therapeutic responses to docetaxel, cisplatin, and gemcitabine. …”
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Advanced omics approaches in liver transplant settings: current applications and future prospectives by Huijuan Wang, Huijuan Wang, Huijuan Wang, Yifeng Zhou, Lu Yu, Lu Yu, Lu Yu, Zhengtao Liu, Zhengtao Liu, Zhengtao Liu, Zhengtao Liu, Shusen Zheng, Shusen Zheng, Shusen Zheng, Shusen Zheng, Shusen Zheng

“…Single-cell RNA sequencing (scRNA-seq) and spatial transcriptomics (ST), as advanced omics technologies, have addressed critical challenges in liver transplantation (LT), the most effective treatment for end-stage liver disease. …”
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Bioinformatics of 1-aminocyclopropane-1-carboxylic acid synthase gene from eggplant and its expression analysis in response to adversity stresses by WAN Faxiang, WANG Lianzhen, GAO Jun

“…The promoter of SmACS gene contained Cis-acting elements related to abscisic acid, ethylene, cold stress, salicylic acid and wound responses. The results of real-time fluorescent quantitative polymerase chain reaction (qRT-PCR) confirmed that the expression of SmACS gene was induced by cold, heat, drought and salt stresses, among which cold stress was the most significant. …”
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Aspergillus fumigatus calcium-responsive transcription factors regulate cell wall architecture promoting stress tolerance, virulence and caspofungin resistance. by Patrícia Alves de Castro, Ana Cristina Colabardini, Adriana Oliveira Manfiolli, Jéssica Chiaratto, Lilian Pereira Silva, Eliciane Cevolani Mattos, Giuseppe Palmisano, Fausto Almeida, Gabriela Felix Persinoti, Laure Nicolas Annick Ries, Laura Mellado, Marina Campos Rocha, Michael Bromley, Roberto Nascimento Silva, Gabriel Scalini de Souza, Flávio Vieira Loures, Iran Malavazi, Neil Andrew Brown, Gustavo H Goldman

“…Here, comparative transcriptomics revealed CrzA and ZipD regulated the expression of shared and unique gene networks, suggesting they participate in both converged and distinct stress response mechanisms. …”
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Metabolic-imaging of human glioblastoma live tumors: A new precision-medicine approach to predict tumor treatment response early by Mariangela Morelli, Francesca Lessi, Serena Barachini, Serena Barachini, Romano Liotti, Romano Liotti, Nicola Montemurro, Paolo Perrini, Orazio Santo Santonocito, Carlo Gambacciani, Matija Snuderl, Francesco Pieri, Filippo Aquila, Azzurra Farnesi, Antonio Giuseppe Naccarato, Paolo Viacava, Francesco Cardarelli, Gianmarco Ferri, Gianmarco Ferri, Paul Mulholland, Diego Ottaviani, Fabiola Paiar, Gaetano Liberti, Francesco Pasqualetti, Francesco Pasqualetti, Michele Menicagli, Paolo Aretini, Giovanni Signore, Sara Franceschi, Chiara Maria Mazzanti

“…BackgroundGlioblastoma (GB) is the most severe form of brain cancer, with a 12-15 month median survival. …”
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Expression Analysis of the ABF Gene Family in <i>Actinidia chinensis</i> Under Drought Stress and the Response Mechanism to Abscisic Acid by Haoyu Wang, Yinqiang Zi, Xu Rong, Qian Zhang, Lili Nie, Jie Wang, Hailin Ren, Hanyao Zhang, Xiaozhen Liu

“…This study analyzed the response of kiwifruit <i>AcABF</i> genes to drought stress. …”
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Nrf2 controls homeostatic transcriptional signatures and inflammatory responses in a cell-type specific manner in the adult mouse brain by Xin He, Owen Dando, Jing Qiu

“…While often linked to anti-inflammatory effects, this is mostly based on studies involving pharmacological activation. …”
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A novel silver-ruthenium-based antimicrobial kills Gram-negative bacteria through oxidative stress-induced macromolecular damage by Patrick Ofori Tawiah, Luca Finn Gaessler, Greg M. Anderson, Emmanuel Parkay Oladokun, Jan-Ulrik Dahl

“…ExPEC strains appear to be more resistant to the proteotoxic effects of AGXX compared to non-pathogenic E. coli, indicating improved defense capabilities of the uropathogen. Global transcriptomic studies of AGXX-stressed ExPEC revealed a strong oxidative stress response, perturbations in metal homeostasis, as well as the activation of heat shock and DNA damage responses. …”
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Role of carbohydrate-active enzymes in brown planthopper virulence and adaptability by Fang Liu, Fang Liu, Jing Xiao, Xin-Feng Wang, Ya-Xuan Wang, Hou-Hong Yang, Yu-Biao Cai, Feng-Xiang Lai, Qiang Fu, Pin-Jun Wan

“…IntroductionHerbivorous insects, including the brown planthopper (BPH), Nilaparvata lugens, are among the most damaging pests to agricultural crops worldwide, particularly rice. …”
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Genome-wide identification of the AcBAM family in kiwifruit (Actinidia chinensis cv. Hongyang) and the expression profiling analysis of AcBAMs reveal their role in starch metabolis... by Xuchen Gong, Mengfei Lin, Jie Song, Jipeng Mao, Dongliang Yao, Zhu Gao, Xiaoling Wang

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Effects of Different Stocking Densities on Snail <i>Bellamya purificata</i> Foot Muscle Nutritional Quality and Metabolic Function by Yingyue Lou, Rui Jia, Bing Li, Linjun Zhou, Jian Zhu, Yiran Hou

“…These findings elucidated the response mechanisms of <i>B. purificata</i> to adverse stocking density conditions and provide data and a theoretical basis for selecting appropriate stocking densities for <i>B. purificata</i>.…”
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Deciphering the role of acetylation-related gene NAT10 in colon cancer progression and immune evasion: implications for overcoming drug resistance by Xuancheng Zhou, Xun Sang, Lai Jiang, Shengke Zhang, Chenglu Jiang, Yuheng Gu, Yipin Fu, Guanhu Yang, Jieyin Zhang, Hao Chi, Binbin Wang, Xiaolin Zhong

“…Abstract Background Colon cancer (CC) is one of the most common and lethal cancers worldwide, with rising incidence rates in both developed and developing countries. …”
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Stress resilience in Coffea arabica and Coffea canephora under harsh drought and/or heat conditions: selected genes, proteins, and lipid integrated responses by José C. Ramalho, José C. Ramalho, Isabel Marques, Isabel P. Pais, Isabel P. Pais, Jean Armengaud, Duarte Gouveia, Ana P. Rodrigues, Danielly Dubberstein, Danielly Dubberstein, Danielly Dubberstein, António E. Leitão, António E. Leitão, Miroslava Rakočević, Paula Scotti-Campos, Paula Scotti-Campos, Sónia Martins, Sónia Martins, Magda C. Semedo, Magda C. Semedo, Fábio L. Partelli, Fernando C. Lidon, Fábio M. DaMatta, Ana I. Ribeiro-Barros, Ana I. Ribeiro-Barros

“…We examined the leaf transcriptomic, proteomic, and membrane lipid responses in two cultivars of the main coffee-producing species—Coffea arabica L. cv. …”
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Less is more: the lack of autoinducer-2-dependent quorum sensing promotes competitive fitness of Escherichia coli strain 83972 by Marla Keizers, Krishnendu Mukherjee, Michael Berger, Ulrich Dobrindt

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Effect of Short-Term Restraint Stress on the Expression of Genes Associated with the Response to Oxidative Stress in the Hypothalamus of Hypertensive ISIAH and Normotensive WAG Rat... by Yulia V. Makovka, Dmitry Yu. Oshchepkov, Larisa A. Fedoseeva, Arcady L. Markel, Olga E. Redina

“…Among the genes of the common response to oxidative stress, the most significant changes in the transcription level were observed in <i>Nos1</i>, <i>Ppargc1a</i>, <i>Abcc1</i>, <i>Srxn1</i>, <i>Cryab</i>, <i>Hspb1</i>, and <i>Fosl1</i>, among which <i>Abcc1</i> and <i>Nos1</i> are associated with hypertension, and <i>Fosl1</i> and <i>Ppargc1a</i> encode transcription factors. …”
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The transcriptional response to yellow and wilt disease, caused by race 6 of Fusarium oxysporum f. sp. Ciceris in two contrasting chickpea cultivars by Aliakbar Faramarzpour, Sara Dezhsetan, Hamid Hassaneian Khoshro, Raheleh Mirdar Mansuri, Hamid Reza Pouralibaba, Zahra-Sadat Shobbar

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