Gene expression analysis of primary graft dysfunction in adult heart transplant recipients: A cohort study by Samuel Padovani Steffen, MD, Alvaro Monteiro Perazzo, MD, MSc, Shirlyne Fabianni Dias Gaspar, MD, Ronaldo Honorato Barros Santos, MD, Domingos Dias Lourenço Filho, MD, PhD, Alexandre da Costa Pereira, MD, PhD, Luis Fernando B. da Costa Seguro, MD, PhD, Fabiana G. Marcondes-Braga, MD, PhD, Fernando Bacal, MD, PhD, Jose Eduardo Krieger, MD, PhD, Fabio Antonio Gaiotto, MD, PhD, Fabio Biscegli Jatene, MD, PhD

“…Results: Eleven genes had their expression significantly different in patients with PGD, with MYL4 the less expressed gene, and related to the myosin function and the gene B3GALT 5 the most expressed one and associated with the inflammatory response. …”
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Identification of the BBX gene family in blueberry at different chromosome ploidy levels and fruit development and response under stress by Yujian Xue, Jiazhuo Chen, Jia Hao, Xiaoyu Bao, Luodan Kuang, Dong Zhang, Chengwen Zong

“…Gibberellin inhibited the expression of most VcBBX genes. Abscisic acid promoted the expression of some members of the BBX family. …”
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Immunometabolism signature derived from on-treatment tumor specimens predicts immune checkpoint blockade response in metastatic melanoma by Shuzhao Chen, Shutong Liu, Jiangtao Song, Xiaojin Li, Huaze Liao, Shuiqin Chen, Yuanbin Song, Yun Wang, Yang Liang, Qianqian Huang, Weiran Lv

“…Abstract Gene signatures have been developed to predict the immune checkpoint blockade (ICB) response and prognosis in patients with melanoma. However, most of these signatures are obtained from pre-treatment biopsy samples, and there is no predictive combination of immune and metabolic signatures from patients receiving treatment. …”
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Pharmacoproteomic characterisation of human colon and rectal cancer by Martin Frejno, Riccardo Zenezini Chiozzi, Mathias Wilhelm, Heiner Koch, Runsheng Zheng, Susan Klaeger, Benjamin Ruprecht, Chen Meng, Karl Kramer, Anna Jarzab, Stephanie Heinzlmeir, Elaine Johnstone, Enric Domingo, David Kerr, Moritz Jesinghaus, Julia Slotta‐Huspenina, Wilko Weichert, Stefan Knapp, Stephan M Feller, Bernhard Kuster

“…Abstract Most molecular cancer therapies act on protein targets but data on the proteome status of patients and cellular models for proteome‐guided pre‐clinical drug sensitivity studies are only beginning to emerge. …”
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Adaptation to Nighttime Light via Gene Expression Regulation in Drosophila suzukii by Natsumi Takenaka, Yuma Takahashi

“…While some species adapt to urban environments, their responses and the role of evolution in urbanization are limited, as most studies focus on phenotypic traits. …”
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Multi-omics analysis reveals the specific role of biocontrol reagents against tomato bacterial wilt by Xin-Qiao Du, Tian-Xiao Sun, Wu-Lin Xu, Tang Zhu, Qiang Wang, Pei-Wen Gu, Jiang Lu

“…In this study, we employed a combination of amplicon sequencing, transcriptomics, and metabolomics analysis to investigate how Bacillus velezensis and Pseudomonas fluorescens affect the defense responses against R. solanacearum in tomato. …”
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Impact of Lysine to Methionine Ratios on Antioxidant Capacity and Immune Function in the Rumen of Tibetan Sheep: An RNA‐Seq Analysis by Fengshuo Zhang, Quyangangmao Su, Zhanhong Gao, Zhenling Wu, Qiurong Ji, Tingli He, Kaina Zhu, Xuan Chen, Yu Zhang, Shengzhen Hou, Linsheng Gui

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Biochemical Defense Arsenal, Genes/QTLs and Transcripts for Imparting Anthracnose Resistance in Common bean (Phaseolus vulgaris L.) by Safoora Shafi, Mohd Tahir, Vanya Bawa, Farkhandah Jan, Neeraj Choudhary, Mohd Anwar Khan, Yogita Singh, Upendra Kumar, Bilal Ahmad Bhat, Waseem Ahmad Dar, Parvaze Ahmad Sofi, Mohd. Ashraf Bhat, Bilal Ahmad Padder, Asif Bashir Shikari, Rajneesh Paliwal, Rajeev Kumar Varshney, Reyazul Rouf Mir

“…Anthracnose (ANT), caused by Colletotrichum lindemuthianum, is the most devastating disease affecting common bean (Phaseolus vulgaris L.), leading to significant yield losses in the Western Himalayas. …”
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Harnessing single-cell and multi-omics insights: STING pathway-based predictive signature for immunotherapy response in lung adenocarcinoma by Yang Ding, Dingli Wang, Dali Yan, Jun Fan, Zongli Ding, Lei Xue

“…BackgroundLung adenocarcinoma is the most prevalent type of small-cell carcinoma, with a poor prognosis. …”
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Human lung organoids reveal conserved CYP1A1 and metallothionein activation in response to particulate matter exposure by Seri Choi, Seung-Yeon Kim, Ji Won Baek, Won Keun Oh, Kee K. Kim, Eun-Mi Kim

“…To address this limitation, we developed functional lung organoids (hLOs) from human pluripotent stem cells that recapitulate the cellular complexity of human lungs for evaluating transcriptomic and toxicological responses to PM exposure. …”
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In silico evaluation of the immunogenic profile of lung cancers with SMARCA4 genetic alterations by Cristina Nieto-Jiménez, Esther Garcia-Lorenzo, Cristina Diaz-Tejeiro, Lucía Paniagua-Herranz, Adrián Sanvicente, Bernard Doger, Irene Moreno, Manuel Pedregal, Jorge Bartolomé, Arancha Manzano, Gyöngyi Munkácsy, Balázs Győrffy, Pedro Pérez-Segura, Emiliano Calvo, Victor Moreno, Alberto Ocana

“…Non-small cell lung cancer (NSCLC) is one of the most immunogenic tumors, but certain genomic alterations can modulate and influence immune response. …”
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The identification of blood-derived response eQTLs reveals complex effects of regulatory variants on inflammatory and infectious disease risk. by Claire Liefferinckx, David Stern, Hélène Perée, Jérémie Bottieau, Alice Mayer, Christophe Dubussy, Eric Quertinmont, Vjola Tafciu, Charlotte Minsart, Vyacheslav Petrov, Alex Kvasz, Wouter Coppieters, Latifa Karim, Souad Rahmouni, Michel Georges, Denis Franchimont

“…Yet, what causal variants and genes in risk loci underpin the observed associations remains poorly understood for most. The identification of colocalized cis-expression Quantitative Trait Loci (cis-eQTLs) is a promising way to identify candidate causative genes. …”
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Exploring Differentially Expressed Genes and Immune Modulation in Diffuse Large B-Cell Lymphoma through RNA Sequencing Analysis by Nor Adzimah Johdi, Amanda Seng, Wei-Kang Lee, Hanif Zulkhairi Mohamad Said, Wan Fariza Wan Jamaluddin

“…Background: Diffuse large B-cell lymphoma (DLBCL) is globally recognized as the most prevalent and aggressive subtype of non-Hodgkin lymphoma. …”
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A multi-omics technology to the study of lactic acid bacteria responses to environmental stress: the past, current and future trends by Yaqi Liu, Jingxian Sun, Xiaowen Liu, Mingpeng Zheng, Wen Ma, Gang Jin

“…While several studies have been carried out in the past by using single-omics techniques to investigate their response to environmental stress, most researchers are now using a multi-omics approach to explore more detail in the biological regulatory networks and molecular mechanisms of lactic acid bacteria in response to environmental stress, thereby overcoming the limitations of single- omics analysis. …”
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Molecular characterization of Echinocandin resistance and the CHS3-mediated adaptive response in Candida glabrata bloodstream infections in Eastern China by Peishan Cong, Biao Wang, Hong He, Xiaoying Li, Lijing Peng, Ji Liu, Hui Guo, Guirong Sun

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Matrix Metalloproteinase‐Responsive Controlled Release of Self‐Assembly Nanoparticles Accelerates Heart Valve Regeneration In Situ by Orchestrating Immunomodulation by Xing Chen, Yunlong Wu, Peng Song, Liandong Feng, Ying Zhou, Jiawei Shi, Nianguo Dong, Weihua Qiao

“…Abstract In situ tissue engineering heart valves (TEHVs) are the most promising way to overcome the defects of existing valve prostheses. …”
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Mitigating Response of <i>SlCSE06</i> Induced by 2-Ethylfuran to <i>Botrytis cinerea</i> Infection by Huilan Ye, Hongdou Gao, Jinnian Li, Linye Lu, Shilan Zheng, Chengxin Wu, Youliang Jin, Chengjuan Cao, Haisheng Zhu, Shuang Liu, Fenglin Zhong

“…In this study, 11 <i>SlCSE</i> family members were identified from the tomato genome using bioinformatics analyses. Public transcriptome databases and RT-qPCR experiments were used to analyze gene expression in tomato tissues, responses to <i>Botrytis cinerea</i> infection, and the temporal characteristics of the response to 2-ethylfuran treatment during infection. …”
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Single-cell sequencing on PBMCs from patients with HA and HB with inhibitors reveals different immune responses to FVIII and FIX by Enhao Li, Zekun Li, Jinzeng Wang, Haoyang Wu, Yilun Xue, Can Lou, Zhenping Chen, Feng Liu, Wenman Wu, Qiulan Ding, Runhui Wu, Xuefeng Wang, Jing Dai

“…Abstract: Inhibitors are the most severe complication of replacement therapy in patients with hemophilia. …”
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Immunotranscriptomic Profiling of <i>Spodoptera frugiperda</i> Challenged by Different Pathogenic Microorganisms by Yan Tang, Qi Zou, Guojie Yu, Feng Liu, Yu Wu, Xueyan Zhao, Wensheng Wang, Xinchang Liu, Fei Hu, Zengxia Wang

“…This study elucidates the immune transcriptome of <i>S. frugiperda</i> in response to various pathogenic microorganisms, providing valuable insights for improving the effectiveness of existing microbial agents and developing new, highly efficient, and specific biopesticides.…”
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Green forage impacts on the DNA methylation in the ruminal wall of Italian mediterranean dairy buffaloes by Salvatore Fioriniello, Angela Salzano, Giovanna Bifulco, Riccardo Aiese Cigliano, Floriana Della Ragione, Giuseppe Campanile

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