Insights into Keratinocyte and Immunologic Landscape in Cutaneous Graft-Versus-Host Disease through Single-Cell Transcriptomics by Amy J. Petty, Adela Rambi Cardones, Yingai Jane Jin, Vaibhav Jain, Emily Hocke, Harsh B. Pathak, Amrita Mitra, Simon G. Gregory, M. Angelica Selim, Jennifer Y. Zhang

“…Cutaneous manifestations are the most common presenting sign of chronic graft-versus-host disease (GVHD), and the extent of cutaneous involvement is also highly correlated with prognosis. …”
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Histological, Transcriptomic, and Functional Analyses Reveal the Role of Gibberellin in Bulbil Development in <i>Lilium lancifolium</i> by Shanshan Du, Mengdi Wang, Jiahui Liang, Wenqiang Pan, Qianzi Sang, Yanfang Ma, Mengzhu Jin, Mingfang Zhang, Xiuhai Zhang, Yunpeng Du

“…Silencing these genes resulted in phenotypes similar to <i>LlGA20ox2</i>, inhibiting bulblet development. Further transcriptomic analysis revealed that gibberellin-responsive genes were enriched in the glucuronate pathway, pentose phosphate pathway and galactose metabolism pathways. …”
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Comparative transcriptome analysis of cucumber fruit tissues reveals novel regulatory genes in ascorbic acid biosynthesis by Jun Ren, Shenzao Fu, Hongyao Wang, Wenying Wang, Xin Wang, Haowen Zhang, Zizheng Wang, Min Huang, Zemiao Liu, Chaobiao Wu, Kun Yang

“…Ascorbic acid (AsA) is one of the most abundant natural antioxidants, and it is an important indicator of the nutritional value of cucumber fruit. …”
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Transcriptomic Profiling of Virus-Host Cell Interactions following Chicken Anaemia Virus (CAV) Infection in an In Vivo Model. by Efstathios S Giotis, Lisa Rothwell, Alistair Scott, Tuanjun Hu, Richard Talbot, Daniel Todd, David W Burt, Elizabeth J Glass, Pete Kaiser

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The network response to Egf is tissue-specific by Beatrice W. Awasthi, João A. Paulo, Deborah L. Burkhart, Ian R. Smith, Ryan L. Collins, J. Wade Harper, Steven P. Gygi, Kevin M. Haigis

“…Here, we carried out integrated phosphoproteomic, proteomic, and transcriptomic analyses of signaling changes across various mouse tissues in response to short-term stimulation with the Egfr ligand Egf. …”
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Developmental air pollution exposure augments airway hyperreactivity, alters transcriptome, and DNA methylation in female adult progeny by Razia Zakarya, Yik Lung Chan, Baoming Wang, Andrew Thorpe, Single-Cell Mouse Lung Disease Atlas Consortium, Dikaia Xenaki, Kin Fai Ho, Hai Guo, Hui Chen, Brian G. Oliver, Christopher O’Neill

“…We interrogate a mouse allergic airway disease model to assess epigenetic associations between maternal air pollution exposure and asthma responses in offspring. Maternal air pollution exposure increased allergic airway disease severity in adult offspring associated with a suppressed transcriptomic response. …”
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Transcriptomics of desiccation tolerance in the streptophyte green alga Klebsormidium reveal a land plant-like defense reaction. by Andreas Holzinger, Andreas Holzinger, Franziska Kaplan, Kathrin Blaas, Bernd Zechmann, Karin Komsic-Buchmann, Burkhard Becker

“…Upon strong desiccation, more than 7000 transcripts showed changes in their expression levels. Most of the highest up-regulated transcripts do not show similarity to known viridiplant proteins, suggesting the existence of some genus- or species-specific responses to desiccation. …”
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Comparative transcriptome analysis reveals key long noncoding RNAs for cadmium tolerance in Tibetan hull-less barley by Md Rafat Al Foysal, Md Rafat Al Foysal, Cheng-Wei Qiu, Feibo Wu

“…This study investigated the response of the lncRNA transcriptome in the roots of two contrasting Tibetan hull-less barley genotypes, X178 (Cd-tolerant) and X38 (Cd-sensitive), to Cd stress using RNA sequencing. …”
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Pathway-based cancer transcriptome deciphers a high-resolution intrinsic heterogeneity within bladder cancer classification by Zhan Wang, Zhaokai Zhou, Shuai Yang, Zhengrui Li, Run Shi, Ruizhi Wang, Kui Liu, Xiaojuan Tang, Qi Li

“…Notably, MA subtype exhibited the most favorable response to immunotherapy, potentially attributable to its distinctive tumor immune microenvironment. …”
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Single-cell transcriptome atlas reveals mitophagy dynamics in acute chemical injury model and the role of MSCs transplantation by Sang Luo, Fang Wu, Xiaojun Yang

“…Abstract Background and purpose Mitochondrial autophagy, also referred to as mitophagy, clears damaged mitochondria and has dual functions in disease development and liver homeostasis in response to liver pathologies. Mesenchymal stem/stromal cells (MSCs) are most commonly used to treat liver failure because they are easy to obtain and present no ethical problems. …”
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Comprehensive Profiling of Transcriptome and m6A Epitranscriptome Uncovers the Neurotoxic Effects of Yunaconitine on HT22 Cells by Beian Lin, Jian Zhang, Mengting Chen, Xinyue Gao, Jiaxin Wen, Kun Tian, Yajiao Wu, Zekai Chen, Qiaomei Yang, An Zhu, Chunhong Du

“…Notably, molecular docking results suggested a stable interaction between YA and most of the differentially expressed m6A regulators. …”
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Integration of single-nuclei and spatial transcriptomics to decipher tumor phenotype predictive of relapse-free survival in Wilms tumor by Ran Yang, Ran Yang, Lulu Xie, Rui Wang, Yi Li, Yifei Lu, Baihui Liu, Shuyang Dai, Shan Zheng, Shan Zheng, Kuiran Dong, Kuiran Dong, Rui Dong, Rui Dong

“…BackgroundWilms tumor (WT) is the most common childhood renal malignancy, with recurrence linked to poor prognosis. …”
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Transcriptomic profiling of ceftriaxone-tolerant phenotypes of Neisseria gonorrhoeae reveals downregulation of ribosomal genes — a pilot study by Sheeba Santhini Manoharan-Basil, Margaux Balduck, Zina Gestels, Said Abdellati, Tessa De Block, Chris Kenyon

“…In the current study, we characterized the transcriptomic profiles of these CRO-tolerant phenotypes. …”
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Transcriptome Analysis of <i>Culex pipiens quinquefasciatus</i> Larvae Exposed to a Semi-Lethal Dose of Vermistatin by Junhui Chen, Zhiyong Xu, Feiying Yang, Jian Yang, Wendong Kuang, Jianghuai Li, Yaqi Wang, Liang Jin

“…Gene Ontology annotation and enrichment analysis revealed the metabolic process to be the most significantly affected biological process, the membrane to be the most significantly affected cellular component, and catalytic activity to be the most significantly affected molecular function. …”
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Identifying ADME-related gene signature for immune landscape and prognosis in KIRC by single-cell and spatial transcriptome analysis by Hongyun Wang, Feizhou Li, Qiong Wang, Xinyuan Guo, Xinbing Chen, Xinrong Zou, Jun Yuan

“…Abstract Kidney renal clear cell carcinoma (KIRC) is the most prevalent subtype of kidney cancer. Although multiple therapeutic agents have been proven effective in KIRC, their clinical application has been hindered by a lack of reliable biomarkers. …”
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Comparative Metabolomic and Transcriptomic Analyses Uncover Variation in Pigment Accumulation Profiles in <i>Alpinia hainanensis</i> Bracts by Tong Zhao, Qianxia Yu, Huanfang Liu, Zehong Wei

“…Although flavonoids are recognized as the primary pigments that color most flowers, the role of their metabolic pathways in shaping the bract color of <i>A. hainanensis</i> ‘Shengzhen’ has not yet been fully explored. …”
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Alleviating effect of vine tea on Aeromonas hydrophila infection revealed by small RNA transcriptome analyses of loach liver by Wenqing Lai, Wenqing Lai, Yuqin Qiu, Shengnan Pan, Aijun Wan, Xueyang Wang, Xueyang Wang, Dingding Lv, Lishang Dai

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Identification of crucial drought-tolerant genes of barley through comparative transcriptomic analysis and yeast-based stress assay by Xiaoyan He, Congjun Su, Xinyi Zhang, Zhaoxia Shi, Yanjie Wang, Huandi Peng, Shuying Fang, Xinyu Chen, Huayan Yin, Jianbin Zeng, Ping Mu

“…Pathway enrichment analyses suggested that these genes are most closely associated with defense responses, signal recognition, photosynthesis, and the biosynthesis of various secondary metabolites. …”
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Profiling X chromosome genes expression relevant to sex dimorphism in stroke: insights from transcriptomics landscape analysis by Xiu-De Qin, Yue-Rong Li, Qian Cai, Jia-Ye Liu, Zhao-Hui Dang, Li-Ling Li, Jia-Wei Min, Shao-Hua Qi, Fan Bu

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Integrated Metabolome and Transcriptome Analyses Reveal the Mechanisms Regulating Flavonoid Biosynthesis in Blueberry Leaves under Salt Stress by Bin Ma, Yan Song, Xinghua Feng, Pu Guo, Lianxia Zhou, Sijin Jia, Qingxun Guo, Chunyu Zhang

“…We also identified 20,920 differentially expressed genes (DEGs) based on transcriptome data; of these, 568 differentially expressed transcription factors (TFs) were annotated, and bHLH123, OsHSP20, and HSP20 TFs might be responsible for blueberry leaf salt tolerance. …”
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