An appropriate DNA input for bisulfite conversion reveals LINE-1 and Alu hypermethylation in tissues and circulating cell-free DNA from cancers. by Trang Thi Quynh Tran, Tung The Pham, Than Thi Nguyen, Trang Hien Do, Phuong Thi Thu Luu, Uyen Quynh Nguyen, Linh Dieu Vuong, Quang Ngoc Nguyen, Son Van Ho, Hang Viet Dao, Tong Van Hoang, Lan Thi Thuong Vo

“…The autonomous and active Long-Interspersed Element-1 (LINE-1, L1) and the non-autonomous Alu retrotransposon elements, contributing to 30% of the human genome, are the most abundant repeated sequences. With more than 90% of their sequences being methylated in normal cells, these elements undeniably contribute to the global DNA methylation level and constitute a major part of circulating-cell-free DNA (cfDNA). …”
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Topical Capsaicin for Treating Cannabinoid Hyperemesis Syndrome by Ansar Aziz, Tayyab Waheed, Olubunmi Oladunjoye, Adeolu Oladunjoye, Midhat Hanif, Fareena Latif

“…With increasing use of marijuana, the incidence of CHS is expected to increase. Most patients with CHS make frequent visits to the emergency room and are usually refractory to conventional treatment. …”
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Persistence of livestock associated MRSA CC398 in humans is dependent on intensity of animal contact. by Haitske Graveland, Jaap A Wagenaar, Kelly Bergs, Hans Heesterbeek, Dick Heederik

“…Nasal and throat swabs were repeatedly taken from each participant for approximately 2 months. …”
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Clinical profile and treatment outcome in chronic recurrent multifocal osteomyelitis: Experience from a tertiary care center in Southern India by Sandeep Surendran, Suma Balan

“…Where available, remission was also corroborated by a repeat MRI. Clinical, radiological and treatment details were compiled. …”
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Artificial Light at Night Advances the Onset of Vocal Activity in Both Male and Female Great Tits During the Breeding Season, While Noise Pollution Has Less Impact and Only in Fema... by Kim Foppen, Rianne Pinxten, Marjolein Meijdam, Marcel Eens

“…The repeatabilities for all chronotype proxies were high, with higher repeatabilities for males. …”
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The role of inflammasomes in hepatocellular carcinoma: Mechanisms and therapeutic insights by Valentina Arrè, Roberto Negro, Gianluigi Giannelli

“…Hepatocellular carcinoma is among the most frequent forms of primary liver cancer and develops within a context of chronic inflammation, frequently associated with a multitude of risk factors, including viral infections, metabolic dysfunction-associated fatty liver disease, metabolic dysfunction-associated steatohepatitis and liver fibrosis. …”
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Use of routinely collected blood donation data for expanded HIV and Syphilis surveillance in Blantyre district, Malawi. by Emmanuel Singogo, Thomas Hartney, Sarah Bourdin, Maganizo Chagomerana, Evaristar Kudowa, Sydney Puerto-Meredith, Bridon M'baya, Godfrey Kadewere, Lucy Platt, Brian Rice, James R Hargreaves, Sharon Weir, Mina C Hosseinipour

“…A total of 23,280 donations from 5,051 donors were recorded, with a median frequency of donations of 3 (IQR:2-6). Most donors were male (4,294; 85%) and students (3,262; 64.6%). …”
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Diversification and recurrent adaptation of the synaptonemal complex in Drosophila. by Rana Zakerzade, Ching-Ho Chang, Kamalakar Chatla, Ananya Krishnapura, Samuel P Appiah, Jacki Zhang, Robert L Unckless, Justin P Blumenstiel, Doris Bachtrog, Kevin H-C Wei

“…Despite being found in most major eukaryotic taxa implying a deeply conserved evolutionary origin, several components of the complex exhibit unusually high rates of sequence turnover. …”
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Comparative analysis of the mitogenomes of multiple species of Fagaceae, with special focus on Quercus gilva by Yu Li, Si-Si Zheng, Gregor Kozlowski, Yi-Gang Song

“…Abstract Background Quercus, as the most abundant and widely distributed genus within the family Fagaceae, has been extensively studied at nuclear genome and plastome. …”
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An In Vitro Comparison of Different Diagnostic Methods in Detection of Residual Dentinal Caries by Nimet Unlu, Rabia Banu Ermis, Sevgi Sener, Ebru Kucukyilmaz, Ali Riza Cetin

“…As a conclusion, LF device is appeared to most reliable method in detection of remain caries in cavity. …”
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Examining Muscle Activity Differences During Single and Dual Vector Elastic Resistance Exercises by Ryan WG Bench, Sydney E Thompson, Alan C Cudlip, Michael WR Holmes

“…Mean, peak and integrated activity were extracted from linear enveloped and normalized data and a 2-way repeated measures ANOVA examined differences between conditions…”
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Experience in Using Breast Single-Photon Emission Computed Tomography with ^99mTc-MIBI by S. P. Shevkina, S. I. Zhestovskaya, V. V. Vyazmin, N. Yu. Shumilina

“…Two patients underwent repeated SPECT and US to analyze the primary tumor response to neoadjuvant chemotherapy.Results. …”
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Variants in exon 11 of MEF2A gene and coronary artery disease: evidence from a case-control study, systematic review, and meta-analysis. by Yan Liu, Wenquan Niu, Zhijun Wu, Xiuxiu Su, Qiujin Chen, Lin Lu, Wei Jin

“…In total, eight variants were identified (21-bp deletion, CAG repeats, CCG repeats, a CCA deletion and four SNPs). …”
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Comparing the effect of dexmedetomidine with magnesium sulfate on hemodynamic changes in patients undergoing laparoscopic cholecystectomy by Mehdi Rajabi, Mehrdad Mahdian, Hossin Akbari, Emad Khan Ahmad

“…No statistically significant difference was seen in most of the measurement times between the three intervention groups. …”
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CYTOGENETIC EFFECTS OF TICK-BORNE TRANSMITTED CO- OR MONOINFECTIONS DEPENDING ON THE VARIANTS OF GLUTATHIONE-S-TRANSFERASE GENES (GSTM1 OR GSTT1) IN THE PATIENT’S GENOTYPE by N. N. Ilyinskikh, E. N. Ilyinskikh, E. V. Zamyatina, V. P. Zuevskiy

“…The material for the study (smears of buccal cells) was obtained repeatedly during admission of patients to treatment, and also after 1 week, 1, 3 and 6 months. …”
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Engineering of long-acting human growth hormone-Fc fusion proteins: Effects of valency, fusion position, and linker design on pharmacokinetics and efficacy. by Taekyeol Lee, Dongsop Lee, Eunee Jung, Mikyung Son, Kyohwan Koo, Jaehoon Choi

“…Bivalent hGH-Fc constructs with shorter linkers (0-1 GGGGS repeats) exhibited higher in vivo exposure (AUC) but lower in vitro activity than those with longer linkers (2-3 repeats). …”
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LIPID-LOWERING THERAPY IN OUTPATIENT PRACTICE (ACCORDING TO THE ARGO-2 STUDY) by N. M. Akhmedzhanov, D. V. Nebieridze, A. S. Safaryan, V. A. Vygodin, A. Yu. Shuraev, A. N. Tkacheva, A. S. Lishuta

“…Rosuvastatin treatment was recommended for all patients. Repeated TC level determination was performed in 7897 patients in an average after 33 days. …”
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The Life and Death of the Manghit Qarachi-bek, Divei by Bakhtin A.G.

“…To identify their role in political events in Eastern Europe and to establish the circumstances of the capture, stay in captivity, and the death of Divei – the most famous of these brothers. Research materials: Chronicles, Razriad books, diplomatic documents, folklore, and secondary materials of historical research. …”
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MMS exposure promotes increased MtDNA mutagenesis in the presence of replication-defective disease-associated DNA polymerase γ variants. by Jeffrey D Stumpf, William C Copeland

“…Disrupting exonuclease activity of mutant variants was not associated with increased spontaneous mutagenesis compared with exonuclease-proficient alleles, suggesting that most or all of the mtDNA was replicated by wild type Mip1. …”
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Safety and efficacy of abatacept among patients with refractory rheumatoid arthritis: Experience from a North Indian Tertiary Care Hospital by M N Arjun, Arun Hegde, Krishnan Shanmuganandan, Darshan S Bhakuni, Kavita Singh, Abhishek Kumar

“…Nearly 52.6% patients achieved primary end-point. Most common adverse effects reported during the study period were headache (14.2%) and upper respiratory tract infection (9.5%). …”
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