The role of VNTR aggrecan gene polymorphism in the development of osteoarthritis in women by D. A. Shapovalova, A. V. Tyurin, S. S. Litvinov, E. K. Khusnutdinova, R. I. Khusainova

“…Twelve allelic variants and 24 genotypes of the VNTR polymorphism of the aggrecan gene (ACAN) were identified, the most frequent variants were alleles with 27, 28 and 26 repeats. …”
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MATERIALS USED IN THE ROAD BASES: METHOD OF THE RESIDUAL DEFORMATIONS’ CALCULATION by A. S. Aleksandrov, T. V. Semenova, N. P. Aleksandrova

“…Therefore, the authors used integral calculus for analytical solution of the residual deformation’s dependence on the number of repeated loads and on the magnitude of the main stresses. …”
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Successful treatment of postoperative nonobstructive recurrent cholangitis by tract conversion surgery after total pancreatectomy: a case report by Masanori Odaira, Fumiki Toriumi, Shota Hoshino, Nozomi Iwama, Yasuhiro Ito, Takashi Endo, Hirohisa Harada

“…Abstract Background Postoperative cholangitis is a complication of biliary reconstruction during hepatobiliary pancreatic surgery. Most cases are associated with anastomotic stenosis, but there are also cases of cholangitis without stenosis, and treatment can be difficult, especially in patients with recurrent symptoms. …”
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Dynamics of anti-Strongyloides IgG antibody responses and implications for strongyloidiasis surveillance in rural Amazonians: A population-based panel data analysis. by Fabiana M de Paula, Bruna B Gomes, Dirce Mary C L Meisel, Mônica da-Silva Nunes, Carlos E Cavasini, Kézia K G Scopel, Ronaldo C B Gryschek, Marcelo U Ferreira

“…Long-lasting high-level IgG responses were most likely due to frequent re-exposure to infective S. stercoralis larvae, chronic carriage of adult worms in the absence of treatment, or both. …”
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Cannabis tolerance reduces symptom relief by Sarah S. Stith, Xiaoxue Li, Franco Brockelman, Keenan Keeling, Branden Hall, Jacob M. Vigil

“…Subsample regressions indicate that experienced users drive most of the effects. Analyses assessing side effects show that factors, such as THC and dose, that increased symptom relief also increased side effects experienced.Conclusion and implicationsThe findings suggest the majority of patients experience decreased symptom relief after repeated use of medical cannabis, counterbalanced by improvements in negative side effects. …”
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Clinical outcomes of participants of a TB prevalence survey with an abnormal chest X-ray but no evidence of TB disease after a median follow-up of 9 months in Zambia and South Afri... by Maria Ruperez, Jacob Busang, Linda Mureithi, Kwame Shanaube, Eveline Klinkenberg, Thomas Gachie, James M Burnett, Barry Kosloff, Petra de Haas, Richard Hayes, Sarah Fidler, Ab Schaap, Sian Floyd, Helen Ayles, TREATS study team

“…Of the 254 eligible TBPS participants 162 (65%) completed follow-up. Most of the participants self-reported previous TB (65% 105/162), were from Zambia (79%, 128/162,) and male (70%, 97/162). …”
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Epilation for minor trachomatous trichiasis: four-year results of a randomised controlled trial. by Esmael Habtamu, Saul N Rajak, Zerihun Tadesse, Tariku Wondie, Mulat Zerihun, Birhan Guadie, Teshome Gebre, Amir Bedri Kello, Kelly Callahan, David C W Mabey, Peng T Khaw, Clare E Gilbert, Helen A Weiss, Paul M Emerson, Matthew J Burton

“…<h4>Conclusions/ significance</h4>Most minor TT participants randomised to the epilation arm continued epilating and controlled their TT. …”
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Adaptive abilities of microscopic red alga <i>Porphyridium purpureum</i> (strain PP-AB11) under change of salinity in the medium by Nina A. Aizdaicher, Inna V. Stonik, Zhanna V. Markina

“…Adaptive abilities of the microscopic red alga Porphyridium purpureum (strain PP-AB11, isolated from the northwestern Japan Sea) are investigated experimentally by its repeated cultivation under various water salinity. …”
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Which Metrics Can I Monitor? Test-Retest Reliability of Countermovement Jump and Countermovement Rebound Jump Force-Time Metrics in Youth Soccer Players In-Season by Andrew Badby, Paul Comfort, Nicholas Ripley, Matthew Cuthbert, Francisco Robles-Palazón, Peter Mundy, John McMahon

“…Objective measures provide the most effective means of monitoring the magnitude and time course of changes in neuromuscular function (NMF) resulting from physical activity if measurements are repeatable (reliability). …”
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The vaccine-site microenvironment: impacts of antigen, adjuvant, and same-site vaccination on antigen presentation and immune signaling by Craig L Slingluff, Pankaj Kumar, Max O Meneveau, Kevin T Lynch, Sapna P Patel

“…Addition of pICLC to IFA + peptide induced an immunologically favorable VSME 1 week after injection but had little impact on the VSME after three injections, compared with IFA + peptide alone. Repeated same-site injection of IFA + peptide antigens induced a VSME with more dendritic cell activation, Th1 dominance, and TLR adaptor protein gene expression than that induced by injections at different, rotating skin locations.Conclusions These data suggest that the vaccine-site itself may be a critically important location contributing to vaccine immunity rather than just the draining lymph node, that IFA induces a favorable VSME with TLR agonist being most beneficial early in the vaccine course, and that same-site injections lead to persistent stimulation of immune pathways that may be beneficial in eliciting antigen specific T cell expansion.…”
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Systematic review and meta-analysis of artemisinin based therapies for the treatment and prevention of schistosomiasis. by Luis Pérez del Villar, Francisco J Burguillo, Julio López-Abán, Antonio Muro

“…<h4>Background</h4>Chemotherapy based on repeated doses of praziquantel is still the most effective control strategy against Schistosomiasis, however artemisinin derivatives emerged as a family of compounds with schistomicide activity. …”
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Pathogenesis of Autoimmunity/Systemic Lupus Erythematosus (SLE) by Shunichi Shiozawa

“…As to the cause of SLE, high levels of interferon α can induce SLE; however, interferon α in most patients did not reach this high level. BAFF (B cell activating factor of the TNF family) is increased in SLE. …”
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Comparative Analysis of the Complete Chloroplast Genomes of Eight <i>Salvia</i> Medicinal Species: Insights into the Deep Phylogeny of <i>Salvia</i> in East Asia by Yan Du, Yang Luo, Yuanyuan Wang, Jiaxin Li, Chunlei Xiang, Meiqing Yang

“…Codon usage favored A/T endings, with leucine (Leu) most frequent and cysteine (Cys) least. We identified 281 long sequence repeats (LSRs) and 345 simple sequence repeats (SSRs), mostly in non-coding regions. …”
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Genomic and protein structural maps of adaptive evolution of human influenza A virus to increased virulence in the mouse. by Jihui Ping, Liya Keleta, Nicole E Forbes, Samar Dankar, William Stecho, Shaun Tyler, Yan Zhou, Lorne Babiuk, Hana Weingartl, Rebecca A Halpin, Alex Boyne, Jayati Bera, Jessicah Hostetler, Nadia B Fedorova, Katie Proudfoot, Dan A Katzel, Tim B Stockwell, Elodie Ghedin, David J Spiro, Earl G Brown

“…Adaptive mutations that control host range and virulence were identified by their repeated selection to comprise a defined model for studying IAV evolution to increased virulence in the mouse.…”
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Trends and Medical Indications of Cesarean Section in the Public Health Sector by Rebar Yahya Abdullah, Harjeen Rasul Mohammed Ali

“…To address this issue, targeted strategies should be developed to reduce both primary and repeat cesarean sections while ensuring maternal and neonatal safety.…”
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Large Language Models can extract morphological data from taxonomic descriptions, but their stochastic nature makes automation challenging: a test on Australian Asteraceae by Alexander N. Schmidt-Lebuhn, Nunzio Knerr

“…However, no widely used central database for morphological data exists as it does for DNA sequences or specimen data. Most of these data are “locked up” in taxonomic literature. …”
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Clinical and Psychopathological Features of Mental Disorders in Patients with Poisoning by Hypotensive and Antiarrhythmic Drugs as a Result of Suicidal Acts by T. I. Dikaya, K. K. Ilyashenko, G. N. Sukhodolova, O. V. Zubareva, M. M. Potskhveriya

“…Among the forms of suicidal behavior, self-poisoning is the most common one, often occurring as a result of taking various medications, the second place among them is occupied by antihypertensive and antiarrhythmic drugs. …”
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Novel candidate genes may be possible predisposing factors revealed by whole exome sequencing in familial esophageal squamous cell carcinoma by Narjes Forouzanfar, Ancha Baranova, Saman Milanizadeh, Alireza Heravi-Moussavi, Amir Jebelli, Mohammad Reza Abbaszadegan

“…A more advanced method to identify new molecular biomarkers predicting disease prognosis can be whole exome sequencing. Here, we report the most effective genetic variants of the Notch signaling pathway in esophageal squamous cell carcinoma susceptibility by whole exome sequencing. …”
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How much missing data is too much to impute for longitudinal health indicators? A preliminary guideline for the choice of the extent of missing proportion to impute with multiple i... by K. P. Junaid, Tanvi Kiran, Madhu Gupta, Kamal Kishore, Sujata Siwatch

“…Results The Repeated Measures- Analysis of variance revealed significant differences between complete and imputed data, primarily in imputed data with over 50% missing proportions. …”
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Morphological and molecular re-assessment of European and Levantine species of the genus Hortiboletus (Boletaceae) by Alona Yu. Biketova, Tatyana Yu. Svetasheva, Andy F. S. Taylor, Giampaolo Simonini, Matteo Gelardi, Olga V. Morozova, Elias Polemis, José A. Muñoz, László Albert, Salvatore Saitta, Solomon P. Wasser, Eviatar Nevo, Georgios I. Zervakis, Alfredo Vizzini, Bálint Dima

“…Hortiboletus (the former Xerocomus rubellus species complex) is one of the most taxonomically critical and difficult genera for species identification in the family Boletaceae. …”
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