Effect of short PSG peptide fragments on the cytokine profile in Wistar rats during allogeneic transplantation <i>in vivo</i> by V. P. Timganova, M. S. Bochkova, K. Yu. Shardina, S. V. Uzhviyuk, E. V. Gutina, M. B. Rayev, A. V. Lyubimov, S. A. Zamorina

“…Thus, it was shown that the use of PSG peptides upon development of immune response to BM allograft may promote a return to normal levels for the most cytokines studied, thus presuming the immunopharmacological potential of these peptides. …”
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Targeting autophagy and plasminogen activator inhibitor-1 increases survival and remodels the tumor microenvironment in glioblastoma by Sophie G. Shifman, Jennifer L. O’Connor, Daniel P. Radin, Aryan Sharma, Laura Infante, Francesca Ferraresso, Christian J. Kastrup, Daniel A. Lawrence, Stella E. Tsirka

“…Abstract Background Glioblastoma (GBM), the most common and aggressive type of primary brain tumor, engages multiple survival mechanisms, including autophagy. …”
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Mind the HAP: an initiative to improve the diagnosis, management and prevention of hospital-acquired pneumonia on the RBH elderly care wards by Charles McLaren, Apurba Chatterjee, Shabnam Iyer, Thanuja Nanayakkara, Patricia Knight, Tanya Demonne, Oscar Amarille, Amanda Adkins, Ruhel Miah

“…A comprehensive teaching module was developed tailored for multidisciplinary teams within the Elderly Care Department. …”
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Screening of potential markers for vitiligo based on bioinformatics and LASSO regression and prediction of Chinese medicine by Wei Liang, Minni Huang, Yue Sun, Shuyu Guan

“…Through weighted gene co-expression network analysis (WGCNA), the core genes in the module most closely related to vitiligo were identified, and an intersection analysis was conducted with the DEGs. …”
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The role of Ikaros transcriptional factor in normal hematopoiesis and leukemogenesis: biological and clinical aspects by V. S. Vshivkoo, A. N. Meleshko

“…Ikaros also normally modulates immune response and plays role of a tumor suppressor in lymphoid malignances. …”
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ARM-X: an adaptable mesenchymal stromal cell-based vaccination platform suitable for solid tumors by Jean Pierre Bikorimana, Nehme El-Hachem, Gabrielle A. Mandl, Daniela Stanga, Jamilah Abusarah, Roudy Farah, Marina P. Gonçalves, Perla Matar, Malak Lahrichi, Sebastien Talbot, Moutih Rafei

“…Results AccuTOX® can indeed trigger MSCs to cross-present antigens, even if pulsed with low doses of tumor antigens while retaining most of the innate properties of A1, including increased antigen uptake and processing, production of reactive oxygen species, endosomal escape and induction of the unfolded protein response (UPR). …”
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Correlation between Serum Levels of Some Immunological Biomarkers and Severity of Idiopathic Immune Thrombocytopenia by Ola A. Hashim, Rawaa N. Alchalabi, Bassam F. Matti, Yaseen I. Mamoori

“…Immune regulatory molecules, including cytokines and immune checkpoint markers, play a vital role in modulating the inflammatory environment and immune tolerance. …”
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MicroRNA: a clinician’s view of the state of the problem. Part 3: MicroRNA and approaches to the treatment of cardiovascular diseases by O. Iu. Mironova, M. V. Berdysheva, E. S. Deeva, E. M. Elfimova

“…Cardiovascular diseases  are one of the most common  causes of death in both developing and developed countries of the world. …”
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Integrative multiomics analysis reveals the subtypes and key mechanisms of platinum resistance in gastric cancer: identification of KLF9 as a promising therapeutic target by Pengcheng Zhang, Lexin Wang, Haonan Lin, Yihui Han, Jingfang Zhou, Hang Song, Peng Wang, Huanhuan Tan, Yajuan Fu

“…Patients with subtype CS2 also exhibited the most adverse therapeutic responses to docetaxel, cisplatin, and gemcitabine. …”
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Facility-Based Delivery during the Ebola Virus Disease Epidemic in Rural Liberia: Analysis from a Cross-Sectional, Population-Based Household Survey. by John Ly, Vidiya Sathananthan, Thomas Griffiths, Zahir Kanjee, Avi Kenny, Nicholas Gordon, Gaurab Basu, Dale Battistoli, Lorenzo Dorr, Breeanna Lorenzen, Dana R Thomson, Ami Waters, Uriah G Moore, Ruth Roberts, Wilmot L Smith, Mark J Siedner, John D Kraemer

“…<h4>Methods and findings</h4>We conducted a two-stage, cluster-sample household survey in Rivercess County, Liberia, in March-April 2015, which included a maternal and reproductive health module. We constructed a retrospective cohort of births beginning 4 y before the first day of survey administration (beginning March 24, 2011). …”
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Inflammatory bowel disease and multiple sclerosis by M. Dominguez-Gallego, V. Meca-Lallana, C. Ana Belén

“…Natalizumab and sphingosine 1-phosphate modulators, such as ozanimod, constitute safer and more effective options for patients with IBD.Regarding treatments for IBD, TNF-α antagonists are contraindicated in patients with MS due to the associated risk of central nervous system demyelination. …”
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SegRD＋＋:Revisiting RD＋＋ for anomaly detection(SegRD++：重新审视基于RD++的异常检测) by 张浚然(ZHANG Junran), 曹俊杰(CAO Junjie)

“…However, the inference approach of RD++ is the same as most previous knowledge distillation methods, which still summarizes the feature differences between the teacher network and the student counterpart in an empirical way. …”
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Usage of an App-Based Addiction Prevention Program for German Vocational Students: Secondary Analysis of Data From a Cluster Randomized Controlled Trial by Diana Guertler, Anne Möhring, Dominic Bläsing, Christian Meyer, Hannah Schmidt, Florian Rehbein, Merten Neumann, Arne Dreißigacker, Anja Bischof, Gallus Bischof, Svenja Sürig, Lisa Hohls, Susanne Wurm, Stefan Borgwardt, Severin Haug, Hans-Jürgen Rumpf

“…On average, participants started 4.8 (SD 5.1) and completed 4.3 (SD 5.2) of 16 weekly in-app chats. Most students (n=903, 71.3%) completed no self-initiated chats, and 50.2% (n=636) stopped using the app before week 3. …”
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EXPLORING DISCOURSE MARKERS IN COMPLAINTS: A COMPARATIVE ANALYSIS OF NATIVE AND NON-NATIVE ITALIAN SPEAKERS by Anna De Marco, Emanuela Paone

“…Native speakers showed the most structured complaints and utilized a diverse array of DMs to balance the illocutionary force of their complaints. …”
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Characteristics and Evolution Trends of Extreme Precipitation in Southern Gaoligong Mountain from 1981 to 2020 by CHEN Wen-hua, ZHANG Ning, FENG Chun-hong, ZHAO Wei-hua, YANG Min

“…[Results] The results showed that except for a significant increase in CDD (3.9 d/(10 a) on the western slope and 0.7 d/(10 a) on the eastern slope), other EPIs exhibited decreasing trends, with PTOT decreasing most significantly (39.9 mm/(10 a) on the western slope and 46.1 mm/(10 a) on the eastern slope), indicating an intensifying drought risk in the region. …”
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Attention Mechanism and Weighted Trend Loss for Wind Speed Correction by Liu Xu, Yang Hao, Liang Xiaoyun, Chen Jing, Li Qiaoping, Li Ruqing, Chen Min

“…The model utilizes a sparse attention mechanism that reduces computational complexity by concentrating on the most relevant interactions within the input data. …”
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Efficient photocatalytic energy harvesting for air purification and electrical generation by Wei Wei, Niansi Li, Xuhui Cao, Guoyu Zhang, Bendong Yu, Jie Ji, Xudong Zhao

“…The photocatalytic interface effectively achieves a high pollutant removal ratio of 77% in the visible light range (<760 nm) and recovers 71.5% of solar energy, while the thermoelectric generator module reaches a maximum power generation efficiency of 0.4% under an irradiation of 1,000 W/m2. …”
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Meningeal malignant solitary fibrous tumor with multiple recurrence, extracranial extension, cervical lymph node metastases: case report and review of the literature by Rong He, Peng Zhong, Juntao Hu, Guangkuo Guo, He Xiao, Lin Lei, Yun Liu, Mingying Geng, Jungang Ma

“…After completion of the treatment course, significant regression of most lesions was observed. However, the patient discontinued clinical follow-up after July 2021. …”
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ADAPTIVE COMFORT PADA GRAND STUDIO PROGRAM STUDI ARSITEKTUR FAKULTAS TEKNIK UNIVERSITAS MALIKUSSALEH by Atthaillah Atthaillah, Eri Saputra, Muhammad Iqbal

“…The result showed that less than 40% of the time from the whole year was thermally comfortable.  The most comfortable and uncomfortable zones consecutively were zone 8 (East, no sun exposure) and zone 20 (South West, sun exposed) which revelead 39.23% and 33.53%  the comfortable time percentage of the whole year. …”
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Upregulated astrocyte HDAC7 induces Alzheimer-like tau pathologies via deacetylating transcription factor-EB and inhibiting lysosome biogenesis by Jinwang Ye, Suyue Zhong, Huali Wan, Xing Guo, Xuanbao Yao, Qiong Liu, Liming Chen, Jian-Zhi Wang, Shifeng Xiao

“…Abstract Background Astrocytes, the most abundant glial cell type in the brain, will convert into the reactive state in response to proteotoxic stress such as tau accumulation, a characteristic feature of Alzheimer's disease (AD) and other tauopathies. …”
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