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4961
Natural Bioactive Compounds Promote Cell Apoptosis in Gastric Cancer Treatment: Evidence from Network Pharmacological Study and Experimental Analysis
Published 2023-01-01“…Gastric cancer (GC) is one of the most lethal cancers. Shenlian capsule (SLC) is a Chinese patent medicine made from 11 herbs containing numerous plant-derived compounds, and the clinical trials of SLCs confirmed that they had effective adjuvant therapy for a variety of cancer such as lung cancer and gastric cancer. …”
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4962
Evaluating the Efficacy of MamaLift Plus Digital Therapeutic Mobile App for Postpartum Depression (SuMMER): Randomized, Placebo-Controlled Pivotal Trial
Published 2025-07-01“…The sham control mimicked the features, functionality, and user experience of the treatment. The most important difference between the 2 arms was that participants in the sham control app did not receive any Cognitive Behavioral Therapy. …”
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4963
Creatinine-modified Child-Turcotte-Pugh score is a good predictor of a short-term survival in patients with bleeding from esophageal varices
Published 2017-01-01“…Patients with bleeding from esophageal varices most often had CTP score rank C (46,9%). CTP score rank B had 37.5% patients, while the smallest percentage of patients had CTP rank A, 15.6% of them. …”
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4964
Nitric Oxide Therapeutics: New Hopes for More Effective Tuberculosis Treatment Combine with Targeted and Controlled Nanotechnology
Published 2025-07-01“…Additionally, it plays a role in modulating immune cell function, contributing to their anti-tuberculosis (anti-TB) effects by regulating macrophage activity. …”
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4965
Engineering n-Type and p-Type BiOI Nanosheets: Influence of Mannitol on Semiconductor Behavior and Photocatalytic Activity
Published 2024-12-01“…This transformation enhanced the density of holes (h<sup>+</sup>) as primary charge carriers and resulted in the most negative conduction band (CB) position (−0.822 V vs. …”
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4966
Tp53 determines the spatial dynamics of M1/M2 tumor-associated macrophages and M1-driven tumoricidal effects
Published 2025-01-01“…EGFR and TP53 are among the most frequently mutated genes in lung adenocarcinoma. …”
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4967
MicroRNAs in the miR-17 and miR-15 families are downregulated in chronic kidney disease with hypertension.
Published 2017-01-01“…In co-expression network analysis of miRNA, one module, which included 13 of the 14 significant miRNAs, had significant association with case status. …”
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4968
Using the Smath Computer Package in School Mathematics Lessons
Published 2025-03-01“…Examples include linear equations and their systems, quadratic equations, equations containing modules, and text problems leading to the construction of equations. …”
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4969
Tumour-associated macrophage infiltration differs in meningioma genotypes, and is important in tumour dynamics
Published 2025-05-01“…Abstract Background Meningiomas are the most common primary intracranial tumours, with clinical behaviours ranging from benign to highly aggressive forms. …”
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4970
Operation features of aviation tankers in the conditions of the Far North
Published 2023-10-01“…The most serious problems are the difficulties of operating a diesel-powered tractor at low temperatures. …”
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4971
NUDT21 regulates lysyl oxidase-like 2(LOXL2) to influence ECM protein cross-linking in silica-induced pulmonary fibrosis
Published 2025-01-01“…Silicosis is a disease caused by prolonged exposure to silica dust. It is the most typical, rapidly progressive, and fatal form of pneumoconiosis. …”
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4972
Serum Metabolomic Profiling in Healthy Dogs Supplemented with Increasing Levels of Purified Beta-1,3/1,6-Glucans
Published 2025-04-01“…Hierarchical heat map analysis revealed differences in metabolite intensity between treatments (<i>p</i> < 0.05). Additionally, the most relevant metabolic pathways were phenylalanine, tyrosine, and tryptophan metabolism; alanine, aspartate, and glutamate metabolism; and glyoxylate and dicarboxylate metabolism. …”
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4973
Three Circulating miRNAs Related to Non-Small-Cell Lung Cancer Progression: An Integrative Analysis of Their Biological Roles
Published 2025-04-01“…To elucidate their biological function, we identified the most significant differentially expressed miRNAs (DE-miRNAs)—hsa-miR-451a, hsa-miR-139-5p and hsa-miR-126-5p—using The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) datasets. …”
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4974
Large-Scale Apple Orchard Identification from Multi-Temporal Sentinel-2 Imagery
Published 2025-06-01“…Accurately extracting large-scale apple orchards from remote sensing imagery is of importance for orchard management. Most studies lack large-scale, high-resolution apple orchard maps due to sparse orchard distribution and similar crops, making mapping difficult. …”
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4975
Exploring immunological alterations of B cells in peripheral immunity via single-cell RNA sequencing: insights into primary membranous nephropathy
Published 2025-08-01“…Furthermore, targeting B cells, such as galectin-9, presents promising opportunities for modulating the immune response in patients with PMN.…”
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4976
Feasibility and acceptability of implementing the Global Scales for Early Development (GSED) package for children 0–3 years across three countries
Published 2025-02-01“…Assessor/supervisor concurrent scoring of assessments proved to be the most cost-effective and straightforward method for evaluating inter-rater reliability. …”
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4977
Primary care practices’ choice of implementation strategy for continuous glucose monitoring for patients with diabetes: a multiple methods study within a larger hybrid type-3 effec...
Published 2025-06-01“…Abstract Background Most diabetes care occurs in primary care. Continuous glucose monitoring (CGM) is associated with clinical, behavioral, and psychosocial benefits. …”
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4978
A high-risk gut microbiota configuration associates with fatal hyperinflammatory immune and metabolic responses to SARS-CoV-2
Published 2022-12-01“…Our study uncovered distinct mechanistic modules that link host and microbiome processes with fatal outcomes to SARS-CoV-2 infection. …”
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4979
Multi task detection method for operating status of belt conveyor based on DR-YOLOM
Published 2025-06-01“…Therefore, the Bottleneck structure in C2f modules of the backbone network P6 and P8 layers is replaced with an Extended Residual Module (DWR), reducing the number of parameters while improving the model's ability to extract multi-scale contextual semantic information. …”
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4980