Showing 21 - 40 results of 371 for search 'most modulating agents', query time: 0.12s Refine Results
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    Reviewing the Etiologic Agents, Microbe-Host Relationship, Immune Response, Diagnosis, and Treatment in Chromoblastomycosis by Luiz Felipe Domingues Passero, Italo Novais Cavallone, Walter Belda

    Published 2021-01-01
    “…Few advances in treatment have been made so far, but one of the most promising ones is based on the use of immunomodulators, such as imiquimod. …”
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    Article
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    Molecular monitoring of short- and long-term transcriptional effects of hair growth stimulating agents. by Sabrina K Henne, Lara M Hochfeld, Werner Bartmann, Thomas Welss, Markus M Nöthen, Stefanie Heilmann-Heimbach

    Published 2024-01-01
    “…Differential expression analyses identified 52 differentially expressed genes and 17 modulated pathways following treatment with the three hair growth stimulating agents. …”
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    Repurposed Antipsychotics as Potential Anticancer Agents: Clozapine Efficacy and Dopaminergic Pathways in Neuroblastoma and Glioblastoma by Catarina Moura, Maria João Gouveia, Nuno Vale

    Published 2025-07-01
    “…These findings support further investigation into dopamine-targeting drugs as potential therapeutic agents in neuro-oncology.…”
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    GOLD(I)-BASED COMPLEX AUDMAP: A PROMISING ANTIPROLIFERATIVE AGENT FOR MELANOMA TREATMENT by Isabela Carvalho Diniz, Fernanda Van Petten de Vasconcelos Azevedo, Camilla Abbehausen, Jennyfer Castro da Silva, Carmen Silvia Passos Lima

    Published 2025-05-01
    “…Introduction/Justification: Melanoma is the most aggressive type of skin cancer, with increasing global incidence. …”
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    Cystic fibrosis treatment; small molecule modulators vs genetic therapy by Salma Aly Elmallah, Raafat Soliman

    Published 2022-10-01
    “…Since the early 2010’s, the development of an actual therapy has reached great milestones including small molecule modulators and genetic therapy. Small molecule therapy depends on the development of small pharmacological agents that can bind to the mutated CFTR protein restoring its function. …”
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    Article
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    Computational discovery of novel aryl hydrocarbon receptor modulators for psoriasis therapy by Gianluca Santini, Laura Bonati, Stefano Motta

    Published 2025-06-01
    “…Among these, immune system modulation, as well as regulation of skin homeostasis and inflammation, make it a promising target for psoriasis therapy. …”
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    Article
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    How culture modulates anthropomorphism in Human-Robot Interaction: A review by Cecilia Roselli, Leonardo Lapomarda, Edoardo Datteri

    Published 2025-05-01
    “…Anthropomorphism is the tendency to attribute human-like characteristics to nonhuman agents, including robots. In the context of Human-Robot Interaction (HRI) research, it is relevant to understand what factors are at play in modulating individuals' anthropomorphism towards robots. …”
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    Cardioprotective effects of the estrogen receptors modulators in the conditions of experimental acute myocardial infarction by K. V. Levchenko, S. V. Gorbachova

    Published 2017-12-01
    “…All the drugs statistically significantly reduced oxidative stress marker products. The most marked effects were displayed by the selective estrogen receptors modulators toremifene and tamoxifen, which decreased in ST2 blood plasma level (by more than 46 %) providing realization of IL 33 cardioprotective properties. …”
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    Gold and Silver Nanoparticles Efficiently Modulate the Crosstalk Between Macrophages and Cancer Cells by Adamecz DI, Veres É, Papp C, Árva H, Rónavári A, Marton A, Vizler C, Gácser A, Kónya Z, Igaz N, Kiricsi M

    Published 2025-04-01
    “…Since it is fairly unknown how the promising anticancer agents, silver (AgNPs) and gold nanoparticles (AuNPs) affect the bidirectional communication and reprogramming in the tumor stroma, we examined the behavior, the tumor-supporting functions, and the expression of polarization and functional marker genes of TAMs to reveal how these are modulated upon interaction with nanoparticle-exposed cancer cells.Methods: We established co-cultures of murine immortalized J774 or primary bone marrow-derived macrophages with 4T1 breast cancer cells treated with AuNPs or AgNPs or with none of the nanoparticles. …”
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    Novel pyran-based anti-inflammatory agents: design, synthesis, and mechanistic studies in LPS-stimulated macrophages by Mei Tong He, Sung Jin Kim, Viet Duc Le, Su Ji Min, Heesu Lee, Jae Wook Lee, Myoung-Sook Shin

    Published 2025-08-01
    “…Our results demonstrate that compound 19 is a promising candidate for the development of novel anti-inflammatory agents.…”
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    Adaptation of Mycoplasmas to Fluoroquinolones: Modulation of Proteome and Genotoxicity of Extracellular Vesicles of Acholeplasma laidlawii by E.S. Medvedeva, T.Y Malygina, N.B. Baranova, А.А. Mouzykantov, M.N. Davydova, O.A. Chernova, V.M. Chernov

    Published 2017-06-01
    “…It has been shown that a significant part of vesicular proteome of A. laidlawii strains with differential sensitivity to ciprofloxacin represents the bacterial virulence factors, as well as that the vesicles of all strains exhibit genotoxicity to lymphocytes of human peripheral blood in vitro. The most important of these results is the fact that the development of resistance of A. laidlawii to ciprofloxacin is accompanied by a significant modulation of vesicular proteome and the increase of mitotoxicity to eukaryotic cells. …”
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    Black Mulberry (Morus nigra L.): A Review of Attributes as an Anticancer Agent to Encourage Pharmaceutical Development by Ana Paula Costa Rodrigues Ferraz, Patrícia de Oliveira Figueiredo, Nídia Cristiane Yoshida

    Published 2024-01-01
    “…Ethanol and methanol extraction methods appear to be the most effective in cancer management, offering compounds that facilitate the integration of apoptosis induction, cell growth inhibition, and cytotoxicity modulation. …”
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