A Case of Inoperable Malignant Insulinoma with Resistant Hypoglycemia Who Experienced the Most Significant Clinical Improvement with Everolimus by Emre Bozkirli, Okan Bakiner, Huseyin Abali, Cagatay Andic, Ali Fuat Yapar, Fazilet Kayaselcuk, Eda Ertorer

“…Close blood sugar monitorization during these therapies showed the most favourable response with everolimus. Everolimus treatment resulted in rapid improvement of hypoglycemia episodes, letting us discontinue dextrose infusion and discharge the patient. …”
Get full text

Angiotensin II therapy in refractory septic shock: which patient can benefit most? A narrative review by Irene Coloretti, Andrea Genovese, J. Pedro Teixeira, Anusha Cherian, Ricard Ferrer, Giovanni Landoni, Marc Leone, Massimo Girardis, Nathan D. Nielsen

“…Abstract Patients with septic shock who experience refractory hypotension despite adequate fluid resuscitation and high-dose noradrenaline have high mortality rates. …”
Get full text

The Three Most Discussed Questions in Carotid Artery Surgery. Review of Russian and Foreign Studies in the Last Five Years by A. S Zharova, K. A. Naumets, V. S. Trishin, G. Yu. Kargatova, R. Yu. Lider, S. V. Artyukhov, A. V. Korotkikh, A. N. Kazantsev

“…This literature review analyzes Russian and foreign publications over the past five years on the three most discussed issues related to carotid artery surgery: 1.Which is more effective: eversion carotid endarterectomy or conventional carotid endarterectomy with patch closure? …”
Get full text

Multiple climate-related stressors in the tropics and beneficial changes in northern latitudes will mostly have emerged before 2050. by Audrey Brouillet, Benjamin Sultan

Get full text

Surgeons consider Rockwood classification the most important factor for decision‐making in acute, high‐grade acromioclavicular dislocations by Eduard Van Eecke, Arno Alexander Macken, Derek van Deurzen, Thibault Lafosse, Antoon van Raebroeckx, Geert Alexander Buijze, Michel van den Bekerom, AC Instability Collaborator Group

“…RW classification was considered the most important factor influencing surgical decision‐making for most surgeons (69%). …”
Get full text

Most TikTok Videos Regarding the Anterolateral Ligament of the Knee Are Posted by Patients and Have Little Educational Value by Riccardo D’Ambrosi, M.D., Thais Dutra Vieira, M.D., Bertrand Sonnery-Cottet, M.D., Ph.D.

“…Results: A total of 55 videos were included in the analysis, of which 4 (7.3%) were posted by physiotherapists; 7 (12.7%), doctors of osteopathic medicine; 38 (69.1%), patients; and 6 (10.9%), medical doctors. Most of the information concerned patient experience (36%-65.5%). …”
Get full text

Which novel teaching strategy is most recommended in medical education? A systematic review and network meta-analysis by Shuai-Long Zhang, Si-Jing Ren, Dong-Mei Zhu, Tian-Yao Liu, Lian Wang, Jing-Hui Zhao, Xiao-Tang Fan, Hong Gong

“…Furthermore, subgroup analysis indicated that CBL (SUCRA = 97.7%) and PBL (SUCRA = 60.3%) were the most effective method for enhancing learning effectiveness within clinical curricula. …”
Get full text

The Exploration of Student Emotion Experience and Learning Experience in E-learning Platform by Fitra Abdurrachman Bachtiar, Riza Setiawan Soetedjo, Joseph Ananda Sugihdarma, Retno Indah Rokhmawati, Lailil Muflikhah

“…Meanwhile, in two-sequence emotion, none of the emotion sequences contributed to the student learning experience. Lastly, three-sequence emotion models also showed that most sequences did not influence student learning experience. …”
Get full text

Foundational Patient Experience: Analyzing 10 Years of Patient Experience Research by Geoffrey Silvera, Courtney Haun, Varun Natarajan

“…The result of this analysis finds the top 10 most cited articles across the first decade of PX scholarship, each having important implications for the future of patient experience.…”
Get full text

Image–Music–Text: Operatic Experiments in the Age of the Audiovisual Essay by João Ricardo

Get full text

General “Maize” as One of the Failed Managerial Experiments of N. S. Khrushchev by A. I. Lushin

“…In turn, the total shortage of meat and dairy products and bakery products in most regions of the country, which has become essentially chronic, has shown the complete failure of some managerial experiments of the First Secretary of the CPSU Central Committee.Conclusions. …”
Get full text

Computational Experiments in Computer Science Research: A Literature Survey by Pablo Landeta-Lopez, Cathy Guevara-Vega

“…It is concluded that performance is the most important measurement in computational experiments and that it is necessary for researchers to rely on a framework so that these experiments can be replicated or refined.…”
Get full text

Experiments on long-term and short-term memory for pitch in musicians by Andrzej RAKOWSKI, Piotr ROGOWSKI

“…On that ground two of them, who revealed faultless, full absolute pitch and one who had most typical relative (non-absolute) pitch, were selected to take part in a case-study-type experiment on short-term memory for pitch. …”
Get full text

Encapsulation of menthol by cyclodextrins-comparison between experiments and molecular simulations by Sa Xu, Fang Wei, Ximing Xu, Rui Wang, Xiujuan Xu, Wu Fan, Guobi Chai, Qidong Zhang, Qingzhao Shi

“…Given the substantial structural differences among flavor ingredients, experimentally deriving the selection criteria for CDs suitable for these flavor substances is a time-consuming process. However, most existing literature relies on the embedding efficiency from practical experiments to evaluate the binding effect between flavor ingredients and CDs. …”
Get full text

Probing the general axion-nucleon interaction in water Cherenkov experiments by Maël Cavan-Piton, Diego Guadagnoli, Axel Iohner, Pablo Fernández-Menéndez, Ludovico Vittorio

“…Our calculations assume the most general axion-quark interactions, with couplings constrained either solely by experimental data, or by specific theory scenarios. …”
Get full text

The effect of rotenone contamination on high-resolution mitochondrial respiration experiments by Dale F. Taylor, Jia Li, Nicholas J. Saner, Jia Wei, Xu Yan, Elizabeth G. Reisman, Hanzhe Li, Matthew J-C Lee, Navabeh Zare, Andrew Garnham, Jujiao Kuang, David J. Bishop

“…Due to the low throughput and high cost of the most used respirometer, the Oroboros 2k (O2k), multiple experiments are often conducted within the same chamber in short succession. …”
Get full text

Reimplantation valve-sparing aortic root replacement is the most durable approach to facilitate aortic valve repairCentral Message by Tirone David, MD

Get full text

Food insecurity and food bank use: who is most at risk of severe food insecurity and who uses food banks? by Elisabeth A Garratt, Beth Armstrong

Get full text

Addressing “what matters most” to reduce mental health stigma in primary healthcare settings: a qualitative study in Lebanon by Racha Abi Hana, Eva Heim, Pim Cuijpers, Marit Sijbrandij, Rabih El Chammay, Brandon A. Kohrt

“…Abstract Background “What matters most” (WMM) is a theoretical framework based on medical anthropology and draws on cultural concepts of values and morals. …”
Get full text

Adventures with the β2-adrenoceptor Receptor: A Career Long Interest in Agonising One of the Most Widely Studied GPCRs by Robin A. Fairhurst

Get full text