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1102
Human lineage mutations regulate RNA-protein binding of conserved genes NTRK2 and ITPR1 involved in human evolution
Published 2024-06-01“…Background The role of human lineage mutations (HLMs) in human evolution through post-transcriptional modification is unclear.Aims To investigate the contribution of HLMs to human evolution through post-transcriptional modification.Methods We applied a deep learning model Seqweaver to predict how HLMs impact RNA-binding protein affinity.Results We found that only 0.27% of HLMs had significant impacts on RNA-binding proteins at the threshold of the top 1% of human common variations. …”
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1103
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Optimizing pyrolysis temperature of contaminated rice straw biochar: Heavy metal(loid) deportment, properties evolution, and Pb adsorption/immobilization
Published 2022-03-01“…We observed that increasing the temperature could volatilize the heavy metal(loid)s. Cd was the most volatile metal therein, followed by As, while Ni, Cu, and Pb were relatively refractory. …”
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1106
Évolution des températures au Burkina Faso entre 1956 et 2015 : cas de Ouagadougou et de Ouahigouya
Published 2018-02-01“…As in Ouagadougou, the freshness are less frequent and the heats more frequent, but the most striking fact here is the rise in minimum temperatures.…”
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1107
Prolonged outpatient parenteral antimicrobial treatment: frequency and evolution over a six-year period in a Swiss University Hospital
Published 2024-11-01“…The objective of this study was to evaluate the frequency and evolution of OPAT courses of ≥ 14 days over the years and determine the medical justification for those prolonged treatments. …”
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1108
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Influence of heating rate on the evolution of post-annealed microstructure in Nb–Ti microalloyed steel: Interplay with initial cold-rolled microstructure
Published 2024-11-01“…Key findings include that increasing the heating rate from 3 °C/s to 30 °C/s enhances the kinetics of reverse transformation to austenite, resulting in a larger fraction of new ferrite and thus a higher proportion of polygonal ferrite in the post-annealed microstructure in most cases. Interestingly, in scenarios where recrystallization can occur by altering the initial microstructure, the combined evolution of recrystallized and new ferrite enlarges the fraction of polygonal ferrite at slower heating rates of 3 °C/s. …”
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1111
Systematic comparison and base-editing-mediated directed protein evolution and functional screening yield superior auxin-inducible degron technology
Published 2025-07-01“…This analysis identifies OsTIR1-based AID 2.0 as the most robust system. However, AID 2.0’s higher degradation efficiency comes with target-specific basal degradation and slower recovery rates. …”
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1112
Similarity Model Test on the Spatiotemporal Evolution Law of Deformation and Failure of Surrounding Rock-Induced Caving in Multi-Mined-Out Areas
Published 2021-01-01“…Based on the monitoring results, it can also be seen that the deformation of overlying rock mass is most affected by the span of the cavity, and the vertical strain is inversely proportional to the depth. …”
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1113
The Evolution of Mechanical Properties and Cellular Structure of Apples During Freeze Drying Combined with Hot Air Drying (FD-HAD) Process
Published 2024-12-01“…Apples are one of the most popular fruits in the world and have a significant share in domestic and international fruit production. …”
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Thermal evolution trend of aromatic hydrocarbons in shales from Permian Dalong Formation in Sichuan Basin and its significance in thermal maturity
Published 2025-05-01“…It was found that the parameters of C-2 DBF-1/MDBF-1 and C-2 DBF-2/MDBF-1 are effective for evaluating shales at mature to over-mature stages (0.8% < Easy Ro < 4.5%), showing a stronger correlation with temperature in the high-temperature evolution stages. This suggests their potential for assessing high to over-mature shales.…”
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1115
SARS-CoV-2 Alchemy: Understanding the dynamics of age, vaccination, and geography in the evolution of SARS-CoV-2 in India.
Published 2025-03-01“…This study investigates the evolution of SARS-CoV-2 via mutation dynamics, focusing on distinct age cohorts, geographical location, and vaccination status within the Indian population, one of the nations most affected by COVID-19.…”
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The Genetic Background and Culture Medium Only Marginally Affect the In Vitro Evolution of <i>Pseudomonas aeruginosa</i> Toward Colistin Resistance
Published 2025-06-01“…Here, we examined whether the genetic background and culture conditions affect the evolution of high-level colistin resistance in this bacterium. …”
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Fly ash admixture originating from lignite combustion in construction mortars – Time evolution of technical parameters and heavy metals leachability
Published 2024-12-01“…The production of cement, the predominant construction binder, is associated with high energy consumption, enormous raw material depletion, and a large volume of CO2 emissions, making cement one of the most polluting materials. This study aims to contribute to the sustainability of the construction industry by significantly reducing the proportion of Portland cement (PC) in the composition of mortars. …”
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Harvesting solutions: Discover the evolution of agriculture wastewater treatment through comprehensive bibliometric analysis using scopus database 1971-2023
Published 2024-01-01“…The analysis also highlights influential authors, institutions, and countries driving research in this field, along with the most cited publications and journals. Additionally, the study identifies research gaps and suggests future research directions in wastewater treatment. …”
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Influence of Source Term Algorithm on Irradiation Induced Microstructure Evolution Based on Cascade Collision Defect Database by Cluster Dynamics Method
Published 2024-06-01“…Cluster dynamics (CD) method is one of the important methods for simulating the microstructure evolution of nuclear materials under high-energy particle irradiation. …”
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Engineering of l-threonine and l-proline biosensors by directed evolution of transcriptional regulator SerR and application for high-throughput screening
Published 2025-01-01“…Notably, six of the newly identified mutants exhibited similarities to the most effective mutants reported to date, indicating the promising application potential of the SerRF104I-based biosensor. …”
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