A 15-year study of neuraminidase mutations and the increasing of S247N mutation in Spain by Iván Sanz-Muñoz, Alejandro Martín-Toribio, Adrián García-Concejo, Irene Arroyo-Hernantes, Marina Toquero-Asensio, Javier Sánchez-Martínez, Carla Rodríguez-Crespo, Silvia Rojo-Rello, Marta Domínguez-Gil, Eduardo Tamayo-Gómez, Marta Hernández-Pérez, José M Eiros

“…Our results showed that the occurrence of NA resistance mutations remained constant in the four viruses during the 15 seasons evaluated, being around 0.5–5 %. Most of the resistance was found in the A(H1N1)pdm09 subtype (around 70 %), especially from the 2023–2024 season onwards, when a significant increase in the occurrence of S247N mutation was observed. …”
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Prediction of Large Solar Flares Based on SHARP and High-energy-density Magnetic Field Parameters by Xuebao Li, Xuefeng Li, Yanfang Zheng, Ting Li, Pengchao Yan, Hongwei Ye, Shunhuang Zhang, Xiaotian Wang, Yongshang Lv, Xusheng Huang

“…Similarly, among the SHARP parameters, the R_VALUE stands out as the most effective parameter for both categorical and probabilistic forecasting.…”
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AdriE: a high-resolution ocean model ensemble for the Adriatic Sea under severe climate change conditions by D. Bonaldo, S. Carniel, R. R. Colucci, R. R. Colucci, C. Denamiel, C. Denamiel, P. Pranić, F. Raicich, A. Ricchi, A. Ricchi, L. Sangelantoni, I. Vilibić, I. Vilibić, M. L. Vitelletti

“…The model performances are mostly aligned with the state-of-the-art reference. …”
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The Construction of an Intrauterine Diagnosis and Treatment System and Comprehensive Lifecycle Health Service of Congenital Heart Disease: Xinhua Hospital Model by Shiwei Jiang, Jiajun Ye, Hualin Wang, Jian Wang, Sun Chen, Yongjun Zhang, Qing Du, Ling Yang, Lei Wang, Kun Sun

“…Congenital heart disease (CHD), as one of the most common congenital birth defects, is the leading cause of mortality in patients aged <5 years, and brings a heavy burden to both the affected families and society. …”
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Centrifugation method for rapid measurement of total soil water-soluble salt by Zhengyang Jia, Zi Chen, Hai Yang, Yun Li, Quanping Zhou, Yuehua Jiang, Yuanyuan Chen, Hong Zhang, Qiuju Qi, Lili Hou, Shijia Mei, Yang Jin

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Assessment of Urban Landscape Patterns to Measure the Effects of Urbanization on Landscape Structure (Case Study: Kermanshah City) by Gholam Reza Sabzghabaei, Soolmaz Dashti, Kaveh Jafarzadeh, Mojgan Bazmara Baleshti

“…1-Introduction The evolution of the spatial structure of a city is the result of economic-socio factors and natural (Tian et al., 2011). …”
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Insights from fifteen years of real-world development, testing and implementation of youth digital mental health interventions by Shane Cross, Shaminka Mangelsdorf, Lee Valentine, Shaunagh O'Sullivan, Carla McEnery, Isabelle Scott, Tamsyn Gilbertson, Shona Louis, Jon Myer, Ping Liu, Niel Mac Dhonnagáin, Tom Wren, Eleanor Carey, Daniela Cagliarini, Ross Jacobs, Roos Pot-Kolder, Imogen Bell, Jennifer Nicholas, Lucia Valmaggia, John Gleeson, Mario Alvarez-Jimenez

“…Drawing on the work of Orygen Digital, we outline the evolution of interventions including the Moderated Online Social Therapy (MOST) platform, the Mello app, and a suite of virtual reality-based therapies; all developed to meet the complex clinical, developmental, and service needs of youth aged 12 to 25.We identify ten key challenges and opportunities encountered in designing, developing and implementing these DMHIs: (1) meaningful co-design; (2) sustained user engagement; (3) personalization and transdiagnostic targeting; (4) optimizing intensities of human support; (5) leveraging peer support and social networking; (6) embedding DMHIs in clinical services; (7) blending digital and face-to-face care; (8) building data infrastructure and learning health systems; (9) developing sustainable and scalable business models; and (10) preparing DMHIs for large language models. …”
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Numerical simulation and experimental study of the temperature field of AlCoCrFeNi2.1 by selective laser melting by Congcong YUE, Ruixiang ZHANG, Wanting SUN, Dongzhou JIA, Ying FU, Xiangqing KONG

“…During SLM, parameters like laser power and scanning speed directly influence the thermal behavior of the molten pool, which in turn affects the microstructure and properties of the AlCoCrFeNi2.1 eutectic high-entropy alloy. Currently, most studies rely on experimental methods; however, complex thermophysical changes during SLM considerably impact the internal thermal behavior of the component. …”
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On Numerical Characteristics of а Simplex and their Estimates by M. V. Nevskii, A. Yu. Ukhalov

“…The authors identify traffic measurements using existing software tools as the most promising approach for traffic estimation, and use Intel Performance Counter Monitor for this purpose. …”
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Developing a multivariate drought index to assess drought characteristics based on the SWAT-Copula method in the Poyang Lake basin, China by Liping Guo, Fusheng Chen, Bin Wang, De Li Liu, Xiulong Chen, Hongsheng Huang, Hua Bai, Kaitao Liao, Zhiming Xia, Keyu Xiang, Linchao Li, Taihui Zheng, Qiang Yu

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Navigating beyond the surface - prognostic significance of KRAS, NRAS, BRAF, PIK3CA, and TP53 mutations examined by exons by Vlad Adrian Afrăsânie, Vlad Adrian Afrăsânie, Mihai Vasile Marinca, Mihai Vasile Marinca, Bogdan Gafton, Bogdan Gafton, Alexandra Rusu, Eliza Maria Froicu, Eliza Maria Froicu, Daniel Sur, Daniel Sur, Cristian Virgil Lungulescu, Raluca Cezara Popa, Irina Afrăsânie, Anca Viorica Ivanov, Georgiana Emmanuela Gîlcă-Blanariu, Lucian Miron, Lucian Miron, Cristina Rusu, Teodora Alexa-Stratulat, Teodora Alexa-Stratulat

“…IntroductionMetastatic colorectal cancer (mCRC) is a disease with various molecular profiles that exhibit different evolution patterns. Although most mCRC patients receive the same chemotherapy drugs in the first-line setting, treatment response is heterogeneous suggesting some tumors are inherently resistant to oxaliplatin/fluoropyrimidine regimen. …”
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Research on dissimilation characteristics and control method of failure of surrounding rock in the roadway with repeated mining of steep and ultra-close multiple coal seam by Housheng JIA, Zhiming ZHANG, Shaowei LIU, Bo PENG, Hui YU, Shuaiqin SHAO, Yibo WANG

“…The internal dislocation position is greater than the distance, which is most favorable for the stability of the surrounding rock of the roadway. …”
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Tidal Debris Candidates from the ω Centauri Accretion Event and Its Role Building Up the Milky Way Halo by Borja Anguiano, Arik W. Mitschang, Takanobu Kirihara, Yutaka Hirai, Danny Horta, Sten Hasselquist, Ricardo P. Schiavon, Steven R. Majewski, Andrew C. Mason, Adrian M. Price-Whelan, Carlos Allende Prieto, Verne V. Smith, Katia Cunha, David L. Nidever

“…Some debris candidates show prograde or retrograde disk-like kinematics, but most show kinematics consistent with the accreted halo, showing high radial actions, J _R , values. …”
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Registry-based surveillance of paediatric home respiratory support in Switzerland: methodology and initial findings by Sophie Guerin, Christian Bieli, Regula Corbelli, Thomas Ferry, Miriam Giaranna, Matthias Horn, Silvia Miano, Nicolas Regamey, Daniel Trachsel, Sylvain Blanchon

“…RESULTS: The registry included 146 patients, and the prevalence of children with home respiratory support in Switzerland was estimated at 11.9/100,000 children (59% boys, 41% girls). The most common underlying medical conditions were related to neuro-muscular (38%) and central nervous system (25%) diseases. …”
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Two Ultralow-mass-ratio Binary Systems at Critical Evolutionary Stages by Di-Fu Guo, Kai Li, Fen Liu, Li-heng Wang, Huai-Zhen Li, Xu Chen, Xiang Gao

“…Notably, J175200 represents the most extreme mass ratio observed in contact binaries to date. …”
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A Catalog of Stellar and Dust Properties for 500,000 Stars in the Southwest Bar of the Small Magellanic Cloud by Petia Yanchulova Merica-Jones, Karl Gordon, Karin Sandstrom, Claire E. Murray, L. Clifton Johnson, Julianne J. Dalcanton, Julia Roman-Duval, Jeremy Chastenet, Benjamin F. Williams, Daniel R. Weisz, Andrew E. Dolphin

“…Our extinction measurements are also sensitive to the presence of the 2175 Å bump in the extinction curve toward UV bright stars. While most do not show evidence for the bump, we identify ∼200 lines of sight that are 2175 Å bump candidates. …”
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A 1985–2023 time series dataset of absolute reservoir storage in Mainland Southeast Asia (MSEA-Res) by S. S. Mahto, S. S. Mahto, S. Fatichi, S. Galelli

“…Such infrastructural evolution demands updates in water management strategies and hydrological models. …”
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Genomic insights into the population structure, antimicrobial resistance, and virulence of Brachyspira hyodysenteriae from diverse geographical regions by Maria Hakimi, Fangshu Ye, Anugrah Saxena, Xiao Hu, Huigang Shen, Paarthiphan Elankumaran, Chloe C. Stinman, Nubia Macedo, Orhan Sahin, Eric R. Burrough, Ganwu Li

“…Virulence factor analysis identified genes linked to hemolysin production, iron uptake, and survival in host environments in most isolates, with a subset of genes demonstrating lineage-specific associations that are further linked to pathogenic potential. …”
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Skeletal Muscle 31P MR Spectroscopy Surpasses CT in Predicting Patient Survival After Liver Transplantation by Denisa Kyselova, Irena Mikova, Petr Sedivy, Monika Dezortova, Milan Hajek, Jan Mares, Marek Tupy, Dana Kautznerova, Marek Kysela, Jiri Fronek, Julius Spicak, Pavel Trunecka

“…Resting muscle metabolism normalized 1 year after LT in most recipients.…”
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Pre-Hospital Point-of-Care Troponin: Is It Possible to Anticipate the Diagnosis? A Preliminary Report by Cristian Lazzari, Sara Montemerani, Cosimo Fabrizi, Cecilia Sacchi, Antoine Belperio, Marilena Fantacci, Giovanni Sbrana, Agostino Ognibene, Maurizio Zanobetti, Simone Nocentini

“…<b>Background</b>: Thanks to the evolution of laboratory medicine, point-of-care testing (POCT) for troponin levels in the blood (hs-cTn) has been greatly improved in order to quickly diagnose acute myocardial infarction (AMI) with an accuracy similar to standard laboratory tests. …”
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