More than the barrier effect: Biodegradable Mg-Ag alloy membranes for guided bone/tissue regeneration by Sihui Ouyang, Xiong Wu, Li Meng, Xuerui Jing, Liying Qiao, Jia She, Kai Zheng, Xianhua Chen, Fusheng Pan

Get full text

Clinical features of patients with ankylosing spondylitis with inefficacy of two or more biological disease modifying antirheumatic drugs by Sh. F. Erdes, K. V. Sakharova, T. V. Dubinina, M. V. Cherkasova

“…The “Treat-to-target” (T2T) strategy for axial spondyloarthritis (axSpA) has made it possible to optimize therapy in most patients, but in some of them the treatment goals are not achieved.Objective: to analyze the clinical features of patients with ankylosing spondylitis (AS) with inefficacy of two or more biological disease modifying antirheumatic drugs (bDMARDs).Material and methods. …”
Get full text

Submovements in manual tracking: people with Parkinson’s disease produce more submovements than age-matched controls by Lior Noy, Sharon Hassin-Baer, Tsvia Fay-Karmon, Noora Kattouf, Simon Israeli-Korn, Robrecht van der Wel, Jason Friedman

“…On the one hand, as PwP move more slowly in day-to-day life, they may be better in a slow tracking task. …”
Get full text

PARP Inhibitors for Metastatic CRPC: More Answers than Questions, a Systematic Review and Meta-Analysis by Ray Manneh, Javier Molina-Cerrillo, Guillermo de Velasco, Linda Ibatá, Susan Martínez, Álvaro Ruiz-Granados, Teresa Alonso-Gordoa

“…PFS2 favored combination therapy (HR = 0.77; 95% CI: 0.64–0.91). Grade ≥3 AEs were more frequent (RR = 1.44; 95% CI: 1.20–1.73). Monotherapy improved rPFS in ITT (HR = 0.46; 95% CI: 0.20–0.81) and BRCAm (HR = 0.33; 95% CI: 0.15–0.75); OS benefit was seen only in BRCAm (HR = 0.73; 95% CI: 0.57–0.95). …”
Get full text

Replacing penalties by V. Stepashin

“…Replacing the punishment more severe as a result of malicious evasion from serving accused designated penalty requires the optimization of the following areas: 1) the selection of a substitute punishment; 2) replacement of proportionality is serving a sentence other (formalization of replacement); 3) ensuring the actual toughening penalties (deterioration of the legal status of the convict). …”
Get full text

Optimization Strategies for Atari Game Environments: Integrating Snake Optimization Algorithm and Energy Valley Optimization in Reinforcement Learning Models by Sadeq Mohammed Kadhm Sarkhi, Hakan Koyuncu

“…The existing research has concentrated more or less on basic DRL approaches though the utilization of advanced optimization methods. …”
Get full text

Judgment Criteria for Reliability Comparison of Three-Terminal Graphs with High Edge Failure Probability by Sun Xie, Haixing Zhao, Jun Yin, Jinyu Zou

“…In this paper, we focus on exploring the characteristics of more reliable three-terminal graphs when the edge failure probability approaches 1. …”
Get full text

Improved Quantum Particle Swarm Optimization of Optimal Diet for Diabetic Patients by Abdellah Ahourag, Zakaria Bouhanch, Karim El Moutaouakil, Abdellah Touhafi

“…Two variations of the particle swarm optimization (PSO) method, as well as random quantum process optimization (GQPSO), are introduced. …”
Get full text

Robotic optimization of powdered beverages leveraging computer vision and Bayesian optimization by Emilia Szymańska, Emilia Szymańska, Josie Hughes

“…Findings demonstrate the effectiveness of robotic automation in achieving high repeatability and enabling extensive exploration of system parameters, paving the way for more advanced and reliable food product development.…”
Get full text

Multi-Strategy Enhanced Parrot Optimizer: Global Optimization and Feature Selection by Tian Chen, Yuanyuan Yi

“…Optimization algorithms are pivotal in addressing complex problems across diverse domains, including global optimization and feature selection (FS). …”
Get full text

Unveiling diabetes onset: Optimized XGBoost with Bayesian optimization for enhanced prediction. by Muhammad Rizwan Khurshid, Sadaf Manzoor, Touseef Sadiq, Lal Hussain, Mohammed Shahbaz Khan, Ashit Kumar Dutta

“…Traditional prediction models, often limited by default parameters, have been superseded by more sophisticated approaches. Leveraging Bayesian optimization to fine-tune XGBoost, researchers can harness the power of complex data analysis to improve predictive accuracy. …”
Get full text

Interpretable Optimization: Why and How We Should Explain Optimization Models by Sara Lumbreras, Pedro Ciller

“…To address these challenges, we propose a framework for interpretable optimization built on three key pillars. First, simplification and surrogate modeling reduce problem complexity while preserving decision-relevant structures, allowing stakeholders to engage with more intuitive representations of optimization models. …”
Get full text

Network reconfiguration and optimal distributed generations allocation with whale optimizer algorithm by Ahmadreza Abdollahi Chirani

“… Power distribution networks have become more interested in Distributed Generations (DG) due to their potential for reducing power loss and improving system dependability. …”
Get full text

Characterization and optimization of heat engines: Pareto-optimal fronts and universal features by Gustavo A L Forão, Jonas Berx, Carlos E Fiore

“…Our results reveal a general trend: while simultaneous optimization over a few parameters typically yields convex Pareto fronts, these fronts become concave as more parameters are varied freely and non-conservative driving becomes significant. …”
Get full text

Assessing the feasibility of CRISPRa approaches to enhance protein-based biomaterial expression in bacterial systems for more efficient production by Pablo Rodríguez-Alonso, Viktoriya Chaskovska, Desiré Venegas-Bustos, Alba Herraiz, Matilde Alonso, Jose Carlos Rodríguez-Cabello

Get full text

Integrating <i>RHD</i> Genotyping for More Accurate Rh(D) Antigen Phenotyping: A Retrospective Study by Mohammad Barouqa, Nestor Dela Cruz

Get full text

How Measurement Affects Causal Inference: Attenuation Bias Is (Usually) More Important Than Outcome Scoring Weights by Joshua B. Gilbert

Get full text

Sudden Cardiac Death in Ischaemic Cardiomyopathy and the Primary Prevention ICD: Time for a More a Personalised Approach? by Saad M Ezad, Girish Babu, Peter O’Kane

“…Guidelines recommend primary prevention implantable cardioverter defibrillator (PPICD) for left ventricular ejection fraction (LVEF) <35% only after 3 months of optimal medical therapy (OMT) or 6 weeks after acute MI with persistent LVEF dysfunction. …”
Get full text

Facilitating the shift to more collaborative microgrids by alleviating demand volatility using a precontracted order updates strategy by Hanaa Feleafel, Jovana Radulovic, Michel Leseure

“…The main conclusion may be summarized as the transition towards more collaborative MGs may serve as the foundation for developing more decentralized electrical networks and integrating more renewable energy sources into the current electricity system.…”
Get full text

Single-dose radiotherapy is more effective than fractionation when combined with anti-PD-1 immunotherapy in glioblastoma by Carolina Cocito, Mylene Branchtein, Xi Kathy Zhou, Tatyana Gongora, Nadia Dahmane, Jeffrey Peter Greenfield

“…Our data show that the 10Gyx1 regimen is more effective than 2Gyx5 at inhibiting tumor cell proliferation and growth in vitro and in vivo. …”
Get full text