Mitochondrial morphology in fertile and infertile men: image processing and morphometric analysis of the sperm midpiece by María Fernanda Skowronek, Santiago Pietroroia, Gabriel de Cola, Mauricio Ramos, Diego Silvera, Gabriela Casanova, Federico Lecumberry, Adriana Cassina, Adriana Cassina, Rossana Sapiro, Rossana Sapiro

“…Ultrastructural analysis further revealed that mitochondria in sperm from infertile men were significantly larger and more irregular in shape compared to those from fertile men. …”
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Hepatocellular carcinoma in Korea: an analysis of the 2016-2018 Korean Nationwide Cancer Registry by Jihyun An, Young Chang, Gwang Hyeon Choi, Won Sohn, Jeong Eun Song, Hyunjae Shin, Jae Hyun Yoon, Jun Sik Yoon, Hye Young Jang, Eun Ju Cho, Ji Won Han, Suk Kyun Hong, Ju-Yeon Cho, Kyu-Won Jung, Eun Hye Park, Eunyang Kim, Bo Hyun Kim

“…However, since approximately half of the patients remained diagnosed at an advanced stage, more rigorous and optimized HCC screening strategies should be implemented.…”
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Unveiling the role of TGF-β signaling pathway in breast cancer prognosis and immunotherapy by Yifan Zheng, Yifan Zheng, Li Li, Wenqian Cai, Lin Li, Rongxin Zhang, Wenbin Huang, Wenbin Huang, Yulun Cao

“…To assess patient risk, we used 101 machine learning algorithms to develop an optimal TGF-β pathway-related prognostic signature (TSPRS). …”
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Unique epitope–antibody interactions in the intrinsically disordered proteoglycan-like domain of human carbonic anhydrase IX defined by high-resolution NMR combined with yeast surf... by Feng Ni, Cunle Wu, Ping Xu, Ping Wang, Yves Fortin, Melanie Arbour, Luke Masson, Denis L’Abbé, Andrea Acel, Mylene Gosselin, Anne E.G. Lenferink

“…Carbonic anhydrase (CA)-IX is an extracellular enzyme that is essential in the adaptation of tumor cells to their increasingly more hypoxic and acidic microenvironment. Within the family of carbonic anhydrases, CA-IX is unique in that it is the only CA with an N-terminal intrinsically disordered region (IDR) containing a proteoglycan (PG)-like domain. …”
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Recent progress on functional hydrogels as biomaterial for biomedicine by Hepeng Yang, Taotao Zeng, Tao Jiang, Qin Wei, Seyed Dariush Taherzade, Xiaolan Peng, Junping Zhu, Zeyan Zhou

“…In the future, combined with 3D printing, microfluidic technology and functional design, hydrogels are expected to play a more important role in personalized medical care and complex tissue regeneration, becoming the next generation of core biomaterials.…”
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Effect of compressive creep in load transfer components on relaxation behavior of FRP cable extrusion anchorages by Jingyang Zhou, Haorui Xiang, Xin Wang, Leizhi Zhang, Xinquan Chang, Qiwei Xu, Zhishen Wu

“…Fibers reduced the 1000-hour creep coefficient more effectively than sand. Excessive stresses and volume fractions decreased strength retention after creep. …”
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Coronavac inactivated vaccine triggers durable, cross-reactive Fc-mediated phagocytosis activities by Lili Wang, Chuang Li, Wanting Li, Liwei Zhao, Tiantian Zhao, Lin Chen, Ming Li, Jing Fan, Jiayan Li, Chao Wu, Yuxin Chen

“…Of note, the ADCP and ADNP responses were more durable and cross-reactive than corresponding Spike-specific IgG titers and neutralizing activities. …”
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Comprehensive analysis on soil nitrogen prediction using near-infrared spectroscopy: Models, methods, and insights for precision agriculture by Xiaoyu Wang, Zhiyou Zhang, Yujiao Li, Jie Li, Qing Yang, Qiqi Liu, Zhijie Gong, Mengling Zhang, Xu Wang, Guanghui Xie

“…The R2c of the calibration set of the soil available nitrogen model ranged from 0.7500 to 0.9421, and RPDc and RPDp value were more significant than 1.5. This study highlights the critical role of soil particle size (optimal at 0.18–0.28 mm), spectral resolution, and preprocessing in enhancing model performance, providing actionable insights for advancing NIRS applications in precision agriculture.…”
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New insights into the mechanisms of electroconvulsive therapy in treatment-resistant depression by Ana C. Ruiz, Abdul Haseeb, William Baumgartner, Edison Leung, Giselli Scaini, Giselli Scaini, Giselli Scaini, Giselli Scaini, Joao Quevedo, Joao Quevedo, Joao Quevedo, Joao Quevedo, Joao Quevedo

“…Moving forward, future research guided by interaction mechanisms hypotheses could provide more insights into alternative neuromodulation techniques, optimize ECT procedures, and improve patient-specific treatment approaches to enhance therapeutic benefits while minimizing adverse effects.…”
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Advantages, applications, and future directions of in vivo aptamer SELEX: A review by Minchuan Lyu, Chi Ho Chan, Ziqi Chen, Yumeng Liu, Yuanyuan Yu

“…This strategy significantly enhances the specificity, functionality, and physiological relevance of the selected aptamers, making them more viable for therapeutic, diagnostic, and imaging applications. …”
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Predictive value of sub classification of focal segmental glomerular sclerosis in Oxford classification of IgA nephropathy by Fang Yu, Xuejing Zhu, Shuguang Yuan, Xiaojun Chen, Zheng Li, Zhong Qu, Hong Liu, Lin Sun, Fuyou Liu

“…We used univariate and multivariate analyses to assess whether the subclassification of S score could refine risk prediction and clinical utility.Results We demonstrated that S lesion ≥ 25% was associated with a more rapid GFR loss and a lower rate of complete remission of proteinuria even adjusted for multiple clinic pathological variables, compared to S1a group (All p values <.05). …”
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Exploring the effect of different tea varieties on the quality of Sichuan Congou black tea based on metabolomic analysis and sensory science by Liran Yang, Xueping Luo, Qi Wang, Mingli Liu, Jingna Yan, Congming Wang, Yuanhua Xian, Kangli Peng, Kunyi Liu, Bin Jiang

“…However, research into optimal processing varieties remains insufficient. …”
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An Overview of 20 Years of Pisco Spirit Research: Trends and Gaps Revealed by a Systematic Review by Erick Saldaña, Jennifer Alvarez, Jaime Laqui-Estaña, Karina Eduardo, Juan D. Rios-Mera, César Augusto Napa-Almeyda, Jhony Mayta-Hancco

“…Moreover, it is important to highlight that the valorization of <i>Pisco</i> by-products opens opportunities for translation into the market, particularly in developing cosmetics, nutritional supplements, and bio-packaging materials, contributing to sustainability and innovation in new industries. However, a more holistic view is still needed in <i>Pisco</i> research. …”
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Deep learning radiomics nomogram predicts lymph node metastasis in laryngeal squamous cell carcinoma by Yun Liang, Yun Liang, Min He, Wenqing Chen, Wenqing Chen, Lizhen Li, Lizhen Li, Yumeng Dong, Yumeng Dong, Gang Liang, Hui Huangfu, Zengyu Jiang, Zengyu Jiang, Sheng He, Sheng He, Sheng He

“…Radiomics features were extracted from CT images, and 7 machine learning algorithms were used to develop 7 radiomics models, which were combined with deep learning features extracted from the ResNet50 deep learning network to form deep learning radiomics (DLR) models. The optimal DLR model was combined with significant clinical imaging features from CT scans to develop the predictive nomogram for LNM in LSCC.ResultsThe nomogram, under receiver operating characteristic (ROC) curve analyses, yielded areas under the curve (AUC) values of, respectively, 0.934 and 0.864 for training and validation sets, significantly higher than clinical imaging features (0.832 and 0.817), conventional radiomics (0.861 and 0.818), and DLR (0.913 and 0.864), indicating that it was significantly more accurate in predicting LNM in LSCC patients. …”
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Addressing the gap in preterm resuscitation practices in high-income and low-middle income countries: a multicenter survey of the Asian neonatal network collaboration by Rinawati Rohsiswatmo, Rizalya Dewi, Jennie Sutantio, Zubair Amin, Young-Ah Youn, Sae Yun Kim, Su Jin Cho, Yun Sil Chang, Satoshi Kusuda, Fuyu Miyake, Tetsuya Isayama

“…Further enhancements are imperative to narrow this gap and optimize neonatal outcomes.…”
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Concentrations and exposure risks of per- and polyfluoroalkyl substances in human milk from Southern China during the first 400 days of lactation by Meng-Tao Yang, Fei Yang, Qiu-Ye Lan, Si-Yu Huang, Xiao-Yan Chen, Ying-Zhen Qiu, Hui-Lian Zhu

“…However, breastfeeding remains the optimal choice due to its significant health benefits. …”
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Estimating Soil Attributes for Yield Gap Reduction in Africa Using Hyperspectral Remote Sensing Data with Artificial Intelligence Methods: An Extensive Review and Synthesis by Nadir El Bouanani, Ahmed Laamrani, Hicham Hajji, Mohamed Bourriz, Francois Bourzeix, Hamd Ait Abdelali, Ali El-Battay, Abdelhakim Amazirh, Abdelghani Chehbouni

“…Effective soil fertility management is an essential key factor for optimizing agricultural productivity while ensuring environmental sustainability. …”
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Incidence and risk factor of blood transfusion after abdominal radical hysterectomy for cervical cancer: a 10-year retrospective study of the US nationwide inpatient sample by Chuan Chen, BenLi Zhu, Youfeng Wang, Yangyang Zhao, Gang Chen, Ying Peng, Ying Peng, Xinyu Wang, Hao Xie, Ying Zhou, Juan Lin

“…Additionally, patients who received transfusions were more likely to experience postoperative delirium, deep vein thrombosis, and wound infection. …”
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Prognostic value of lymph node ratio in patients with non-small cell lung cancer: a systematic review and meta-analysis by Junhuang Zheng, Junhuang Zheng, Junhuang Zheng, Junhuang Zheng, Junhuang Zheng, Haoyu Zhong, Enxiang Quan, Zhiyan Gao, Songsong Ying, Songsong Ying, Songsong Ying, Songsong Ying

“…Background and purposeThe lymph node ratio (LNR), by indirectly quantifying the dynamic balance between metastatic burden and host immune clearance, may provide more accurate prognostic stratification information. …”
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Effects of interventions with resistance exercises on muscle strength, physical disability, and quality of life in systemic sclerosis patients: a systematic review with meta-analys... by André Luiz Silveira Mallmann, Daniel Nóbrega de Moraes, Lucas Denardi Dória, Leonardo Peterson dos Santos, Stephanie Pilotti, Mayra Angélica de Souza Antunes, Laura Fontana Steinmetz, Thauan Júnior Santos de Souza, Vanessa Hax, Jerri Luiz Ribeiro, Ricardo Machado Xavier, Rafael Mendonça da Silva Chakr

“…More robust studies are required to refine training methods and enhance clinical trial designs.…”
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