Delayed Recovery After Exercise-Induced Pain in People with Chronic Widespread Muscle Pain Related to Cortical Connectivity by Mark D. Bishop, Meryl J. Alappattu, Priyanka Rana, Roland Staud, Jeff Boissoneault, Shelby Blaes, Yonah Joffe, Michael E. Robinson

“…Conclusions: A standardized muscle “injury” protocol resulted in more pain, a longer time to peak pain, and a longer time to resolve pain in the patient group compared to the NP group. …”
Get full text

Quantitative Systems Pharmacology Model to Predict Target Occupancy by Bruton Tyrosine Kinase Inhibitors in Patients With B‐Cell Malignancies by Oleg Demin Jr, Ying Ou, Galina Kolesova, Dmitry Shchelokov, Alexander Stepanov, Veronika Musatova, Sri Sahasranaman, Yating Zhao, Xiangyu Liu, Zhiyu Tang, William D. Hanley

“…This model describes pharmacokinetics of BTK inhibitors; intracellular concentration of BTK inhibitors in peripheral blood mononuclear cells (PBMCs), BM, and lymph nodes (LNs); binding of BTK inhibitors with BTK; and BTK turnover rate. …”
Get full text

Tumor Response to Neoadjuvant Long-Course Chemoradiotherapy Depends on the Rectal Cancer Patient Gender by Velda Smajlbegović, Snježana Ramić, Iva Kirac, Meliha Solak Mekić, Loris Ćurt, Danko Velimir Vrdoljak

“…The post-LCCRT pathologic finding showed that women had more positive lymph nodes (ypN, p=0.002) while no other pathologic parameter differed significantly between the genders. …”
Get full text

Missing value interpolation algorithm for long-term temperature observation data based on data augmentation multiple interpolation method by Xiaolin Liu, Bo Wang, Shuanglong Jin, Zongpeng Song

“…This method can provide a more accurate basis for subsequent data analysis and application.…”
Get full text

Constructing A Knowledge-driven and Data-driven Hybrid Decision Model for Etiological Diagnosis of Ventricular Tachycardia by WANG Min, HU Zhao, XU Xiaowei, ZHENG Si, LI Jiao, YAO Yan

“…The hybrid model adopted a knowledge-driven decision-making framework, embedding the XGBoost model into the decision nodes of a two-level classification. The precision, recall, and F1 scores of the three models were as follows: the knowledge-driven model achieved 80.4%, 79.1%, and 79.7%; the data-driven model achieved 88.4%, 88.5%, and 88.4%; and the hybrid model achieved 90.4%, 90.2%, and 90.3%.ConclusionsThe hybrid model integrating knowledge-driven and data-driven approaches demonstrated higher accuracy, and all its decision outcomes were based on evidence-based practices, aligning more closely with the actual diagnostic reasoning of clinicians. …”
Get full text

X-RAY MORPHOLOGICAL SEMIOTICS OF NON-TUBERCULOUS MYCOBACTERIAL PULMONARY DISEASE by R. B. Amansakhedov, L. N. Lepekha, L. I. Dmitrieva, I. Yu. Andrievskaya, A. T. Sigaev, N. N. Makar’yants, V. V. Romanov, A. E. Ergeshov

“…The dissemination foci in mycobacterial diseases were characterized by their location in the lung parenchyma with vascular and bronchial involvement and reactive changes in the pulmonary pleurae and intrathoracic lymph nodes (ITLN). In 92.7% of cases, the detected foci were predominantly centrilobular with endobronchial localization. …”
Get full text

Análisis de eficiencia de protocolos de enrutamiento en implementación de Red Inalámbrica Mesh en instalaciones de la Facultad de Ingeniería en Electricidad y Computación (FIEC) re... by E. Jiménez, J. Zerna, Patricia Chavez, Juan Carlos Basurto

“…However, one of the main challenges in the research of this kind of networks is to offer increased scalability, this is why the quality of service (QoS) plays an important factor on its implementation, because the increase of the nodes implies that there is an increase of delay, since the packets must pass through more nodes to their final destination. …”
Get full text

Novel role of microphthalmia-associated transcription factor in modulating the differentiation and immunosuppressive functions of myeloid-derived suppressor cells by Yoon Kyung Jeon, Aram Lee, Haesun Park, Soyoung Lim, Jihyun Lim, Jaemoon Koh, Young Yang, Myeong-Sok Lee, Jong-Seok Lim

“…Furthermore, IHC staining of human tumor tissues revealed that MITF+ MO-MDSCs are more frequently observed in tumor tissues than in tumor-free draining lymph nodes obtained from patients with cancer.Conclusions Our results indicate that MITF regulates the differentiation and function of MDSCs and can be a novel therapeutic target for modulating MDSC activity in immunosuppressive TMEs.…”
Get full text

Análisis de eficiencia de protocolos de enrutamiento en implementación de Red Inalámbrica Mesh en instalaciones de la Facultad de Ingeniería en Electricidad y Computación (FIEC) re... by E. Jiménez, J. Zerna, Patricia Chavez, Juan Carlos Basurto

“…However, one of the main challenges in the research of this kind of networks is to offer increased scalability, this is why the quality of service (QoS) plays an important factor on its implementation, because the increase of the nodes implies that there is an increase of delay, since the packets must pass through more nodes to their final destination. …”
Get full text

The comparison of the radiation load to the heart and the left anterior descending coronary artery for various modes of radiation treatment of the breast cancer patients by A. V. Bondarenko, L. I. Korytova, E. A. Maslyukova, O. V. Korytov, E. M. Muravnik

“…For each mode of radiation the doze-volume parameters of organs at risk were estimated: heart volume exposed to more than 25 Gy (V25 heart), mean dose (Dmean) to the heart and left anterior descending coronary artery (LAD).Results. …”
Get full text

Análisis de eficiencia de protocolos de enrutamiento en implementación de Red Inalámbrica Mesh en instalaciones de la Facultad de Ingeniería en Electricidad y Computación (FIEC) re... by E. Jiménez, J. Zerna, Patricia Chavez, Juan Carlos Basurto

“…However, one of the main challenges in the research of this kind of networks is to offer increased scalability, this is why the quality of service (QoS) plays an important factor on its implementation, because the increase of the nodes implies that there is an increase of delay, since the packets must pass through more nodes to their final destination. …”
Get full text

Two-Tier Marketplace with Multi-Resource Bidding and Strategic Pricing for Multi-QoS Services by Samira Habli, Rachid El-Azouzi, Essaid Sabir, Mandar Datar, Halima Elbiaze, Mohammed Sadik

“…However, allocating resources from heterogeneous fog nodes often faces limited capacity. To overcome these limitations, integrating fog nodes with cloud resources is crucial, ensuring that Service Providers (SPs) have adequate resources to deliver their services efficiently. …”
Get full text

The inhibitor of apoptosis proteins antagonist Debio 1143 promotes the PD-1 blockade-mediated HIV load reduction in blood and tissues of humanized mice. by Michael Bobardt, Joseph Kuo, Udayan Chatterji, Norbert Wiedemann, Gregoire Vuagniaux, Philippe Gallay

“…Anti-PD-1 mAb administration reduced HIV load in blood by 94%, and addition of D1143 further enhanced this reduction from 94 to 97%. D1143 also more profoundly promoted with the anti-PD-1-mediated reduction of HIV loads in all tissues analyzed including spleen (71 to 96.4%), lymph nodes (64.3 to 80%), liver (64.2 to 94.4), lung (64.3 to 80.1%) and thymic organoid (78.2 to 98.2%), achieving a >5 log reduction of HIV loads in CD4+ cells isolated from tissues 2 weeks after drug treatment interruption. …”
Get full text

Symptoms of herpesvirus infection in reproductive disorders in married couples by E. K. Shushakova, V. S. Markina, S. V. Nikolaeva, T. A. Ruzhencova

“…Gynecological examination of women with HSV-1, 2 more often revealed cracks in the posterior adhesions, vesicular erosive elements of the external genitalia, contact bleeding, enlargement of the uterus and enlargement of inguinal lymph nodes. …”
Get full text

Job system generation in grid taking into account user preferences by D. M. Yemelyanov, P. A. Potekhin, V. V. Toporkov

“…Distributed computing environments like Grid are characterized by heterogeneity, low cohesion and dynamic structure of computing nodes. This is why the task of resource scheduling in such environments is complex. …”
Get full text

Pattern of computed tomography scan findings in children with Wilms′ tumor in a tertiary hospital in Lagos, Nigeria by A Adegboyega Olukayode, I Osuoji Richard, A Akinola Rachael, O Balogun Babajide, O Faturoti Ireti, O Awosanya Gbolahan

“…The right sided tumors were slightly more than the left and nearly 25% were bilateral. …”
Get full text

Global determinants of breast cancer mortality: a comprehensive meta-analysis of clinical, demographic, and lifestyle risk factors by Zelalem G. Dessie, Temesgen Zewotir

“…By utilizing a large dataset, this review aims to provide a more robust understanding of the key determinants influencing breast cancer outcomes. …”
Get full text

EXPERIENCE OF SUCCESSFUL ACNEFORM ERUPTIONS TREATMENT IN PATIENT WITH MULTIPLE MELANOMA by O. V. Minkina, A. S. Dvornikov, P. A. Skripkina, T. A. Gaydina, E. V. Trushina

“…Subsequently, the patient was verified metastasis in the inginal lymph nodes, in the soft tissues of the hips, to liver. …”
Get full text

Intelligent design and implementation of blockchain and Internet of things–based traffic system by Qilei Ren, Ka Lok Man, Muqing Li, Bingjie Gao, Jieming Ma

“…In real-life traffic scenarios, it may generate more complex system and data security issues, which will be elaborated and analyzed at the end of this article. …”
Get full text

Less locus coeruleus degeneration and its enhanced influence on neural circuit in Parkinson's tremor by Junyan Sun, Lili Chen, Liang Li, Tao Wu, Tao Feng

“…Spectral dynamic causal modeling based on resting-state functional MRI accessed the effective connectivity from locus coeruleus to the cerebello-thalamo-cortical circuit. The pivotal nodes of cerebello-thalamo-cortical circuit included ventral intermediate nucleus, motor cortex, and cerebellum. …”
Get full text