System-Technology Co-Optimization for Dense Edge Architectures Using 3-D Integration and Nonvolatile Memory by Leandro M. Giacomini Rocha, Mohamed Naeim, Guilherme Paim, Moritz Brunion, Priya Venugopal, Dragomir Milojevic, James Myers, Mustafa Badaroglu, Marian Verhelst, Julien Ryckaert, Dwaipayan Biswas

“…Our exploration with two diverse workloads—image resolution enhancement (FSRCNN) and eye tracking (EDSNet)—shows that more resources allow better workload mapping possibilities, which are able to compensate peak system energy efficiency degradation on high memory capacity cases. …”
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Toward Fine Horizontal Resolution Global Simulations of Aerosol Sectional Microphysics: Advances Enabled by GCHP‐TOMAS by Betty Croft, Randall V. Martin, Rachel Y.‐W. Chang, Liam Bindle, Sebastian D. Eastham, Lucas A. Estrada, Bonne Ford, Chi Li, Michael S. Long, Elizabeth W. Lundgren, Saptarshi Sinha, Melissa P. Sulprizio, Yidan Tang, Aaron vanDonkelaar, Robert M. Yantosca, Dandan Zhang, Haihui Zhu, Jeffrey R. Pierce

“…GCHP's architecture allows massively parallel GCHP‐TOMAS simulations including on the cloud, using hundreds of computing cores, faster runtimes, more memory, and finer global horizontal resolution (e.g., 25 km × 25 km, 7.8 × 105 model columns) versus the previous single‐node capability of GEOS‐Chem‐TOMAS (tens of cores, 200 km × 250 km, 1.3 × 104 model columns). …”
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Laparoscopic Radical Colectomy with Complete Mesocolic Excision Offers Similar Results Compared with Open Surgery by Vasile V. Bintintan, Vlad Fagarasan, Radu I. Seicean, David Andras, Alexandru I. Ene, Romeo Chira, Adriana Bintintan, Georgiana Nagy, Cristina Petrisor, Simona Cocu, Elena Stefanescu, Ionut Negoi, Adrian Calborean, George C. Dindelegan, Ciprian Silaghi, Iulia Lupan, Gabriel Samasca

“…Laparoscopy has been proven to bring significant advantages to colorectal surgery but performing a laparoscopic CME (Lap-CME) for colonic cancer is even more technically demanding than CME in open surgery. …”
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Clinicopathological characterization of Switch/Sucrose-non-fermentable (Swi/Snf) complex (ARID1A, SMARCA2, SMARCA4)-deficient endocervical adenocarcinoma by Chao Cao, Zi-Yun Wu, Wei Liao, Li-Jun Wei, Hao-Yu Liang, Xia Yang, Rong-Zhen Luo, Li-Li Liu

“…Swi/Snf-deficient ECA demonstrated higher PD-L1 combined positive score (CPS) positivity (P < 0.001), and was more frequently associated with mismatch repair deficiency (MMRD, P < 0.001). …”
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Antitumor effect of a new human epidermal growth factor receptor inhibitor by O. I. Kit, I. P. Kodonidi, E. M. Frantsiyants, I. V. Kaplieva, A. A. Glushko, L. K. Trepitaki, E. I. Surikova, V. A. Bandovkina, Yu. A. Pogorelova, I. V. Neskubina, O. V. Bykadorova, E. V. Serdyukova

“…The dynamics of animal weight, dynamics of tumor node volume were evaluated, the tumor growth inhibition index (TGII) was calculated.Results. …”
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Tumor Deposits as an Adverse Prognostic Indicator in Stage III Colon Cancer: A Multicenter Database Study by Jeeyou Kim, MD, Dong Woon Lee, MD, Ji Won Park, MD, PhD, Seung-Bum Ryoo, MD, PhD, Heung-Kwon Oh, MD, PhD, Rumi Shin, MD, PhD, Jin Sun Choi, MD, Min Jung Kim, MD, Sung-Chan Park, MD, Duck-Woo Kim, MD, PhD, Seung Chul Heo, MD, PhD, Sung-Bum Kang, MD, PhD, Seung-Yong Jeong, MD, PhD, Kyu Joo Park, MD, PhD, Jae Hwan Oh, MD, PhD, On Behalf of the Seoul Colorectal Research Group (SECOG)

“…Patients were classified according to the number of metastatic lymph nodes (LNs) (0/1–3/≥4) and the presence of TDs. Results:. …”
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Recent advances of photodiagnosis and treatment for head and neck squamous cell carcinoma by Yining Zhang, Zhenfang Li, Chengchi Zhang, Chengying Shao, Yanting Duan, Guowan Zheng, Yu Cai, Minghua Ge, Jiajie Xu

“…Due to the complex anatomy and the lack of intraoperative modalities to accurately determine the incision margins, surgeons are in a dilemma between extensive tumor removal and improving the quality of patient survival. As more knowledge is gained about HNSCC, the increasing recognition of the value of optical imaging has been emphasized. …”
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Molecular testing for cytologically suspicious and malignant (Bethesda V and VI) thyroid nodules to optimize the extent of surgical intervention: a retrospective chart review by Jessica Hier, Galit Avior, Marc Pusztaszeri, Joshua R. Krasner, Noura Alyouha, Veronique-Isabelle Forest, Michael P. Hier, Alex Mlynarek, Keith Richardson, Nader Sadeghi, Michael Tamilia, Richard J. Payne

“…The aim of this study was to determine whether patients who had molecular testing in Bethesda V and VI thyroid nodules had the optimal extent of surgery performed more often than patients who did not have molecular testing performed. …”
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GPR87 promotes invasion and migration through the RHO/ROCK pathway in non-small cell lung cancer by LIU Chenxi, HAN Lin, YANG Yi, ZHOU Han, LIU Yayun, SHENG Deqiao

“…Patients with higher expression of GPR87 had worse clinical stage and were more prone to lymph node metastasis, suggesting that GPR87 might be a key gene for the high invasiveness of NSCLC. …”
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Contemporary outcomes of patients undergoing robotic-assisted radical cystectomy: A comparative analysis between intracorporeal ileal conduit and neobladder urinary diversions by Jordan M. Rich, Shivaram Cumarasamy, Daniel Ranti, Etienne Lavallee, Kyrollis Attalla, John P. Sfakianos, Nikhil Waingankar, Peter N. Wiklund, Reza Mehrazin

“…The IC group had a higher proportion of patients with pathological tumor stage 2 (pT2) tumors (34 [17.9%] vs. 10 [14.1%], p=0.008) and pathological node stages pN2–N3 (28 [14.7%] vs. 3 [4.2%], p<0.001). …”
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Efficacy and safety of pyrotinib in the treatment of HER2-positive liver metastatic advanced breast cancer by Yongxia Li, Yongxia Li, Yong Li, Taolang Li, Mingyuan He, Mingyuan He, Jianying Chang, Jianying Chang, Hui Cao, Daiqin Luo, Daiqin Luo, Junyuan Lv, Yunbi Zou, Yuyan Zheng, Li Ran, Li Ran, Feiyue Yang, Li Huang, Xiaoming Cheng

“…Univariate analysis revealed that patients with younger age (&lt;60 years) (P &lt; 0.0001), negative progesterone receptor expression (P = 0.0028), higher Ki67 expression levels (P &lt; 0.0001), and absence of lymph node metastasis (P &lt; 0.0001) were more likely to benefit from pyrotinib treatment. …”
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Axillary adipose tissue–derived lymphatic endothelial cells exhibit distinct transcriptomic signatures reflecting lymphatic invasion status in breast cancer by Asumi Iesato, Jun Suzuka, Kazutaka Otsuji, Tomo Osako, Nami Yamashita, Yuka Inoue, Tetsuyo Maeda, Natsue Uehiro, Kazuyo Yoshida, Yoko Takahashi, Kohei Kumegawa, Sumito Saeki, Liying Yang, Ai Tsuchiya, Kana Sakiyama, Miwa Tanaka, Takehiko Sakai, Shinji Ohno, Tetsuo Noda, Takayuki Ueno, Reo Maruyama

“…This study emphasizes the importance of using patient-derived cells to accurately assess the tumor microenvironment, potentially leading to more personalized therapeutic approaches.…”
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BRCA1 promoter hypermethylation is not associated with germline variants in Polish breast cancer patients by Karolina Prajzendanc, Paweł Domagała, Jolanta Hybiak, Wojciech Kluźniak, Cezary Cybulski, Katarzyna Białkowska, Alicja Ogrodniczak, Janusz Ryś, Aleksandra Sejda, Marek Szwiec, Joanna Tomiczek-Szwiec, Tomasz Kluz, Roksana Dwornik, Dagmara Cylwik, Jacek Gronwald, Jan Lubiński, Anna Jakubowska

“…Nevertheless, a borderline association was observed between rs799905 and the occurrence of triple-negative breast cancer (TNBC) (p = 0.048) as well as lymph node (LN) metastases (p = 0.046). Among BRCA1 PV carriers, the GG genotype was significantly more frequent, while the CC genotype was 10 times less common compared to non-carriers (p = 0.003). …”
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SMART SPECIALISATION AS A BASIC COMPONENT OF SOCIO-ECONOMIC DEVELOPMENT by Olena Guzenko, Svitlana Nikolaichuk, Dmytro Ivanenko

“…The authors have set the task of formulating the main segments of the SS concept as a priority component of increasing the competitiveness of regions, improving their socio-economic climate and proposing a modernization of the conceptual category "SS of socio-economic development of regions" for a more substantive definition of the directions of innovative regional policy. …”
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Effectiveness of minimally invasive methods (laser-induced interstitial thermotherapy and percutaneous ethanol sclerotherapy) in the treatment of Plummer’s disease by O.A. Tovkai, V.O. Palamarchuk, N.V. Smolovyk, P.O. Lishchynskyi, L.V. Stotska, A.R. Yatsiv, V.V. Kuts

“…Clinical outcomes are significantly more favorable in small toxic adenomas than in large nodes…”
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Simulation analysis of path planning for workpiece clamping robots based on digital twin technology by Xin PAN, Min LIANG, Yanchao YIN, Zhong CHEN

“…Targeting feasible regions through elliptical constraints accelerates convergence toward optimal paths, while techniques such as redundant node elimination and initial path smoothing further improve path quality, resulting in shorter, smoother routes. …”
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Projections of Temperature and Precipitation Changes under CMIP6 Scenarios in Sistan-va-Baluchestan Province by S. Mirshekari, F. Yaghoubi, S.A. Hashemi

“…Extreme climatic conditions have become frequent and more intense in recent decades as a result of human activities. …”
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Depression, performance status, and discontinued treatment mediate an association of curability belief with prognosis in advanced cancer patients by Je-Yeon Yun, Ju Youn Jung, Bhumsuk Keam, Na-Ri Lee, Jung Hun Kang, Yu Jung Kim, Hyun-Jeong Shim, Kyung Hae Jung, Su-Jin Koh, Hyewon Ryu, Shin Hyu Yoo, EunKyo Kang, Young Ho Yun

“…In terms of healthcare utilization, patients with curability belief were more likely to receive standard or advanced anti-cancer therapy, while those without curability belief tended to suspend or discontinue therapy (P < 0.001). …”
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IGZO 2T1C DRAM With Low Operation Voltage and High Current Window by Wendong Lu, Kaifei Chen, Menggan Liu, Fuxi Liao, Zijing Wu, Naide Mao, Zihan Li, Xuanming Zhang, Congyan Lu, Jiebin Niu, Bok-Moon Kang, Jing-Hong Shi, Xie-Shuai Wu, Gui-Lei Wang, Zhengyong Zhu, Jiawei Wang, Lingfei Wang, Di Geng, Nianduan Lu, Guanhua Yang, Chao Zhao, Ling Li

“…Furthermore, the proposed novel 2T1C bit-cell provides a more reliable gate-controlled read scheme. This work paves the forward way for low voltage and reliable sensing IGZO DRAM application.…”
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Prognostic value of tertiary lymphoid structures in triple-negative breast cancer: integrated analysis with the tumor microenvironment and clinicopathological features by Florence Boissière-Michot, Marie-Christine Chateau, Simon Thézenas, Virginie Lafont, Evelyne Crapez, Evelyne Crapez, Priyanka Sharma, Angélique Bobrie, Angélique Bobrie, Pascal Roger, Séverine Guiu, Séverine Guiu, William Jacot, William Jacot, William Jacot, William Jacot

“…TNBC with higher PT-TLS abundance displayed more often a basal-like (p&lt;0.001) and not molecular-apocrine phenotype (p&lt;0.001). …”
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