HSP90 and HSP70: Implication in Inflammation Processes and Therapeutic Approaches for Myeloproliferative Neoplasms by Margaux Sevin, François Girodon, Carmen Garrido, Aurélie de Thonel

“…Besides their chaperone and cytoprotective functions, HSPs are key players during inflammation, hence the term “chaperokine.” …”
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The Flash Vacuum Expansion Process Increases the Bioaccessibility and Stability of Antioxidant Compounds in Papaya Puree During Digestion by Teresita de Jesús Castillo-Romero, Leticia Xochitl López-Martínez, Marco Antonio Salgado-Cervantes, Eber Addí Quintana-Obregón, Gustavo Adolfo González-Aguilar, Manuel Vargas-Ortiz

“…Our results show that the FVE process significantly enhances the bioaccessibility and stability of antioxidant compounds, providing a clear advantage over the conventional method. Fruit purees generated by FVE can be an ingredient that increases the functionality of foods (juices, nectars, purees, ice creams, and yogurt) aimed at people with digestive problems, baby food, or the use of fruits with low commercial value.…”
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AUV Online Path Planning Strategy Based on Sectorial Gridded Detection Area by Yang Liu, Jinxi Sun, Guojie Li, Xiujun Xu

“…Then, a comprehensive cost function combining safety, smoothness, and cost is utilized to generate the optimal heading. …”
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Investigation of Diabetes Care in Elder Individuals Using Artificial Intelligence by Sonali Vyas, Sachin Gupta, Sandhya Tarar, Batyrkhan Omarov, Bhasker Pant, Jyoti L. Bangare, Tapas Bhowmik

“…Patients with such ailments tend to generate more data and information related to the disease and health-related aspects. …”
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ALDH^High Breast Cancer Stem Cells Exhibit a Mesenchymal–Senescent Hybrid Phenotype, with Elevated Metabolic and Migratory Activities by Luis Larrea Murillo, Conor J. Sugden, Bela Ozsvari, Zahra Moftakhar, Ghada S. Hassan, Federica Sotgia, Michael P. Lisanti

“…Cancer stem cells (CSCs) account for 0.01 to 2% of the total tumor mass; however, they play a key role in tumor progression, metastasis and resistance to current cancer therapies. The generation and maintenance of CSCs are usually linked to the epithelial–mesenchymal transition (EMT), a dynamic process involved in reprogramming cancer cells towards a more aggressive and motile phenotype with increased stemness potential. …”
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Stimulus representation in human frontal cortex supports flexible control in working memory by Zhujun Shao, Mengya Zhang, Qing Yu

“…Here, we tested the hypothesis that stimulus representation persists in the frontal cortex to facilitate flexible control demands in WM. During functional MRI, participants flexibly switched between simple WM maintenance of visual stimulus or more complex rule-based categorization of maintained stimulus on a trial-by-trial basis. …”
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In-situ catalysis of green lubricants into graphitic carbon by iron single atoms to reduce friction and wear by Wei Song, Chongyang Zeng, Xiaoyang Ma, Janet S. S. Wong, Chuke Ouyang, Shouyi Sun, Weiwei Zhang, Jianbin Luo, Xing Chen, Jinjin Li

“…Due to its anti-friction and wear properties, DOM holds promise to replace conventional additives, and thus provides a green and more effective alternative for next-generation lubricant formulations.…”
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Traversability Analysis and Path Planning for Autonomous Wheeled Vehicles on Rigid Terrains by Nan Wang, Xiang Li, Zhe Suo, Jiuchen Fan, Jixin Wang, Dongxuan Xie

“…Afterward, the TV-Hybrid A* algorithm is proposed by redefining the path cost functions of the Hybrid A* algorithm through the simulation data and neural network method to generate a more cost-effective path. …”
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How Can We Engage Oncology Care Providers and Glioblastoma Patients in Conversations About Physical Activity: A Qualitative Descriptive Study Using the Theoretical Domains Framewor... by Jodi E. Langley, Grace Warner, Christine Cassidy, Robin Urquhart, Mary MacNeil, Melanie R. Keats

“…The data were then analyzed using a directed content analysis using a codebook generated using the TDF. Patients and family/friend caregivers appreciated hearing about PA from their OCPs, from initial diagnosis into follow-up appointments, and they saw PA as a way to take a break from cancer/medically focused care, and historical PA behaviours did not mean patients were more or less likely to be open about PA discussions. …”
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Importance of Target Gene Locus on the Stability of Recombinant Viruses in the Baculovirus Expression System by Jong Ho Lee, Dong-Hyun Lee, Hyuk-Jin Moon, Soo Dong Woo

“…In the baculovirus expression system, recombinant viruses generated via bacmids often exhibit reduced expression and genetic stability of target genes during serial passages. …”
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Integrating patient metadata and pathogen genomic data: advancing pandemic preparedness with a multi-parametric simulator by Bonjean Maxime, Ambroise Jérôme, Orchard Francisco, Sentis Alexis, Hurel Julie, Hayes Jessica S., Connolly Máire A., Jean-Luc Gala

“…Abstract Stakeholder training is essential for handling unexpected crises swiftly, safely, and effectively. Functional and tabletop exercises simulate potential public health crises using complex scenarios with realistic data. …”
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Combining 3‐D Probabilistic Kinematic Modeling With Thermal Resetting Measurements: An Approach to Reduce Uncertainty in Exhumation Histories by Sofia Brisson, Denise Degen, David Nathan, Florian Wellmann, Christoph vonHagke

“…The resulting, more robust model can then be used to re‐interpret the thermal resetting data. …”
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Infiltration Pattern of Blood Monocytes into the Central Nervous System during Experimental Herpes Simplex Virus Encephalitis. by Rafik Menasria, Coraline Canivet, Jocelyne Piret, Guy Boivin

“…To distinguish microglia from blood monocyte-derived macrophages, chimeras were generated by conditioning C57BL/6 recipient mice with chemotherapy regimen followed by transplantation of bone morrow-derived cells that expressed the green fluorescent protein. …”
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Tocilizumab in combination with corticosteroids: potential for managing cancer cachexia with systemic hyperinflammation by Ping Chen, Dingyi Wang, Zhouwei Zhan, Ling Chen, Yu Chen

“…Weight, body mass index, liver metastasis, Eastern Cooperative Oncology Group score, patient-generated subjective global assessments, the Anorexia/Cachexia Subscale of the Functional Assessment of Anorexia/Cachexia Therapy, handgrip strength, neutrophil-to-lymphocyte ratio, and the C-reactive protein, hemoglobin, prealbumin, and albumin levels were recorded in both groups.ResultsTocilizumab treatment favorably influenced the levels of patient biomarkers (p<0.05), ameliorated systemic inflammation, and demonstrated enhanced clinical short-term efficacy compared to the control group, including rates of symptomatic relief (60% vs. 20%, p = 0.024), improvement of serum PAB and ALB (70% vs. 25%, p = 0.004), weight gain >2% (45% vs. 15%, p = 0.038), and improvement of grip strength and 6-m walk speed (p<0.05). …”
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The Impact of Test Number on the Mechanical Properties of Dracaena Draco Cellulose Fibers for Composite Structures: Weibull Statistic by Abdelwaheb Hadou, Ahmed Belaadi, Messaouda Boumaaza, Boon Xian Chai, Mahmood M. S. Abdullah, Ibrahim M. H. Alshaikh, Amar Al-Khawlani, Djamel Ghernaout

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Analysis of Visitor Perceptions of Malang City Thematic Parks using a Text Mining Approach by Nur Izza Vania, Aisyah Larasati, Yuh-Wen Chen, Nikmatus Sholikha

“…City parks, as representations of GOS, can be enhanced through thematic development and place branding to improve user engagement and functional value. This study aims to analyze visitor perceptions of thematic parks by identifying high-frequency keywords extracted from user-generated reviews. …”
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Development of biometric systems for passenger identification based on noise-resistant coding means by A. A. Gladkikh, A. K. Volkov, T. G. Ulasyuk

“…The basic elements and the principle of the classical biometric system functioning are presented. On the basis of the International Civil Aviation Organization (ICAO) recommendations, the procedure features of pattern recognition are presented. …”
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Massively parallel sequencing reveals the complex structure of an irradiated human chromosome on a mouse background in the Tc1 model of Down syndrome. by Susan M Gribble, Frances K Wiseman, Stephen Clayton, Elena Prigmore, Elizabeth Langley, Fengtang Yang, Sean Maguire, Beiyuan Fu, Diana Rajan, Olivia Sheppard, Carol Scott, Heidi Hauser, Philip J Stephens, Lucy A Stebbings, Bee Ling Ng, Tomas Fitzgerald, Michael A Quail, Ruby Banerjee, Kai Rothkamm, Victor L J Tybulewicz, Elizabeth M C Fisher, Nigel P Carter

“…Here, the combination of next generation sequencing, array-CGH and fluorescence in situ hybridization technologies has enabled us to identify unsuspected rearrangements of Hsa21 in this mouse model; revealing one deletion, six duplications and more than 25 de novo structural rearrangements. …”
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A novel antibody against human properdin inhibits the alternative complement system and specifically detects properdin from blood samples. by Diana Pauly, Benedikt M Nagel, Jörg Reinders, Tobias Killian, Matthias Wulf, Susanne Ackermann, Boris Ehrenstein, Peter F Zipfel, Christine Skerka, Bernhard H F Weber

“…Thus, in vitro anti-properdin mAb 1340 was up to fifteen times more efficient in blocking the complement system as compared to anti-C5 or anti-Ba antibodies. …”
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Assessing the Influence of Selected Permeabilization Methods on Lymphocyte Single-Cell Multi-Omics by Shifan Ding, Na Lu, Hassan Abolhassani

“…(1) Background: Single-cell multi-omics is a powerful method for the dissection and detection of complicated immunologic functions and synapses. However, most currently available technologies merge datasets of different omics from separate portions of the same sample to generate combined multi-omics. …”
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